Cytoskeleton provides fully validated reagents for ubiquitin research. In particular a fully characterized affinity bead reagent for enriching mono- and poly-ubiquitin modified proteins (see Cat.# UBA01). In addition, a highly specific ubiquitin antibody is available for probing western blots and performing immuno-fluorescence in situ. The antibody was raised against full length bovine ubiquitin. The antibody has been shown to recognize polyubiquitin and free ubiquitin (Fig 1). Ubiquitin is a highly conserved protein and AUB01 is predicted to recognize ubiquitin from a wide range of species (5). AUB01 is purified by Protein G affinity chromatography and is supplied as a lyophilized white powder.