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Small G-protein and signal transduction products
Cytoskeleton, Inc. has the widest line of G-protein related products on the market. Cytoskeleton sells purified proteins, a large number of Biochem Kits to assay the biology and biochemistry of small G-proteins as well as antibodies to G-proteins and related proteins. We also provide many of our purified proteins on agarose beads, ready for different affinity purification methods. See each individual product page for examples of uses.
Purified proteins
GTPases
Effector fragments
GTPase activating protein (GAPs)
Guanine nucleotide dissociation inhibitors (GDIs)
Guanine nucleotide exchange factors (GEFs)
Modifying enzymes
Small G-protein and signal transduction Biochem Kits
Antibodies to small G-proteins and related molecules
Purified proteins
GTPases
Cdc42 protein, GST-tagged, wild type [GST-Cdc42]
Cdc42 protein, His-tagged, wild type [His-Cdc42]
Cdc42 protein, His-tagged, constitutively active [His-Cdc42(Q61L)]
Cdc42 protein, GST-tagged, dominant negative [GST-Cdc42(T17N)]
H-Ras protein, His-tagged, wild type [His-H-Ras]
H-Ras protein, GST-tagged, constitutively active [GST-H-Ras(G12V)]
Rac1 protein, GST-tagged, wild type [GST-Rac1]
Rac1 protein, His-tagged, wild type [His-Rac1]
Rac1 protein, His-tagged, constitutively active [His-Rac1(Q61L)]
Rac1 protein, GST-tagged, dominant negative [GST-Rac1(T17N)]
Ran protein, His-tagged, wild type [His-Ran]
Ran protein, His-tagged, constitutively active [His-Ran(Q69L)]
Ran protein, His-tagged, dominant negative [His-Ran(T24N)]
Rap1a protein, His-tagged, wild type [His-Rap1a]
Rap1b protein, His-tagged, wild type [His-Rap1b]
RhoA protein, GST-tagged, wild type [GST-RhoA]
RhoA protein, His-tagged, wild type [His-RhoA]
RhoA protein, His-tagged, constitutively active [His-RhoA(Q63L)]
RhoC protein, His-tagged, wild type [His-RhoC]
GTP-gamma-S (non-hydrolyzable analog of GTP, for preparing "active conformation" of G-proteins
Effector fragments
PAK p21-binding domain protein, GST-tagged [GST-PAK-PBD]
PAK p21-binding domain protein on agarose beads, GST-tagged [GST-PAK-PBD beads]
Raf Ras-binding domain protein on agarose beads, GST-tagged [GST-Raf-RBD beads]
RanBP1 protein, His-tagged [His-RanBP1]
Rhotekin Rho-binding domain protein, GST-tagged [GST-Rhotekin-RBD]
Rhotekin Rho-binding domain protein on agarose beads, GST-tagged [GST-Rhotekin-RBD beads]
WASP Cdc42-binding domain protein on agarose beads, GST-tagged [GST-WASP-CBD beads]
GTPase activating protein (GAPs)
p50RhoGAP protein, GST-tagged, full length [GST-p50RhoGAP]
p50RhoGAP protein, GST-tagged, catalytic domain [GST-p50RhoGAP, catalytic]
Guanine nucleotide dissociation inhibitors (GDIs)
Rho guanine nucleotide dissociation inhibitor protein-1, GST-tagged [GST-RhoGDI-1]
Guanine nucleotide exchange factors (GEFs)
Dbs RhoGEF domain protein, His-tagged [His-Dbs-DH/PH]
Modifying enzymes
C3 transferase protein
Cell Permeable Rho Inhibitor
Small G-protein and signal transduction Biochem Kits
Cdc42 activation assay, pull down, (BK034)
EasyRad phosphate assay (BK055)
RhoA activation assay, G-LISA, absorbance based (BK124)
RhoA activation assay, G-LISA, luminometry based (BK121)
RhoA/B/C activation assay, G-LISA, absorbance based (BK123)
Rac1,2,3 activation assay, G-LISA, absorbance based (BK125)
Rac1 activation assay, G-LISA, luminometry based (BK126)
Rac activation assay, pull down, (BK035)
Ras activation assay, pull down, (BK008)
RhoA activation assay, pull down, (BK036)
RhoGAP assay (BK105)
RhoGEF exchange assay (BK100)
Antibodies to G-proteins and related molecules
Anti-pan-Rac, polyclonal (rabbit)
Anti-Rac1 specific, monoclonal (mouse)
Anti-Ras, monoclonal (mouse)
Anti-RhoA specific, monoclonal (mouse)
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