Signal-Seeker™: Identifying Potential PTM Crosstalk of Acetylated Mitochondrial Proteins


- Identification of endogenous Ub, SUMO 2/3, pY and Ac PTMs for 4 mitochondrial target proteins 

- Acetylation state validation of 10 mitochondrial target proteins

- Investigated changes in mitochondrial target proteins PTM profiles in response to hydrogen peroxide 

- Detected changes in mitochondrial protein acetylation by immunofluorescence  

        Products used:

        Signal-Seeker™ Phosphotyrosine Enrichment Kit (Cat. # BK160 or BK160-S)

        Signal-Seeker™ Ubiquitination Enrichment Kit (Cat. # BK161 or BK161-S)

        Signal-Seeker™ SUMOylation 2/3 Enrichment Kit (Cat. # BK162 or BK162-S)

        Signal-Seeker™ Acetyl-Lysine Enrichment Kit (Cat. # BK163 or BK163-S)

        For more specific information about Signal-Seeker™ protein modification detection tools please view our product pages, resource links, or contact technical support.