- Home
- Activation Assay Validation Data and Citations
Cytoskeleton Inc Activation Assay Validation Data and Citations
Activation Assay Citations
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Gao, Fei et al. | STARD13 is positively correlated with good prognosis and enhances 5-FU sensitivity via suppressing cancer stemness in hepatocellular carcinoma cells | OncoTargets and Therapy | 2018 | ISSN 1178-6930 |
| Rafiq, Nisha Bte Mohd et al. | Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO | The Journal of cell biology | 2017 | ISSN 1540--8140 |
| Rennoll-Bankert, Kristen E. et al. | RalF-Mediated Activation of Arf6 ControlsRickettsia typhiInvasionby Co-Opting Phosphoinositol Metabolism | Infect Immun | 2016 | PMID 27698019 |
| Schultz, Mark L. et al. | CLN3 Deficient Cells Display Defects in the ARF1-Cdc42 Pathway and Actin-Dependent Events | PLOS ONE | 2014 | ISSN 1932--6203 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Borghesan, Elizabeth et al. | A Brucella effector modulates the Arf6‐Rab8a GTPase cascade to promote intravacuolar replication | The EMBO Journal | 2021 | ISSN 0261--4189 |
| Jackson, Matilda R. et al. | Heterozygous loss of function of IQSEC2/Iqsec2 leads to increased activated Arf6 and severe neurocognitive seizure phenotype in females | Life Science Alliance | 2019 | ISSN 2575-1077 |
| Rafiq, Nisha Bte Mohd et al. | Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO | The Journal of cell biology | 2017 | ISSN 1540--8140 |
| Stepicheva, Nadezda A. et al. | The small GTPase Arf6 regulates sea urchin morphogenesis | Differentiation; research in biological diversity | 2017 | ISSN 1432-0436 |
| Biesemann, Anja et al. | Rab35 protein regulates evoked exocytosis of endothelial Weibel-Palade bodies | The Journal of biological chemistry | 2017 | ISSN 1083--351X |
| Rennoll-Bankert, Kristen E. et al. | RalF-Mediated Activation of Arf6 ControlsRickettsia typhiInvasionby Co-Opting Phosphoinositol Metabolism | Infect Immun | 2016 | PMID 27698019 |
| Andrews, Allison M. et al. | Mechanical Injury Induces Brain Endothelial-Derived Microvesicle Release: Implications for Cerebral Vascular Injury during Traumatic Brain Injury | Frontiers in Cellular Neuroscience | 2016 | ISSN 1662-5102 |
| Marchesin, Valentina et al. | ARF6 promotes the formation of Rac1 and WAVE-dependent ventral F-Actin rosettes in breast cancer cells in response to epidermal growth factor | PLoS ONE | 2015 | ISSN 1932-6203 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Zi, Jingjing et al. | PFN1 Inhibits Myogenesis of Bovine Myoblast Cells via Cdc42-PAK/JNK | Cells | 2022 | ISSN 2073-4409 |
| Jiang, Ruiwei et al. | CDC42 governs normal oviduct multiciliogenesis through activating AKT to ensure timely embryo transport | Cell Death & Disease 2022 13:9 | 2022 | ISSN 2041--4889 |
| Meng, Zhipeng et al. | The Hippo pathway mediates Semaphorin signaling | Science Advances | 2022 | ISSN 2375-2548 |
| Merlin, Johanna et al. | Non-canonical glutamine transamination sustains efferocytosis by coupling redox buffering to oxidative phosphorylation | Nature Metabolism | 2021 | ISSN 2522-5812 |
| Ma, Yuanyuan et al. | Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during tooth root development | Development (Cambridge) | 2021 | ISSN 1477-9129 |
| Vallejo, Daniela et al. | Wnt5a modulates dendritic spine dynamics through the regulation of Cofilin via small Rho GTPase activity in hippocampal neurons | Journal of Neurochemistry | 2021 | ISSN 1471-4159 |
| Wurzer, Hannah et al. | Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome In Vitro by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton Remodeling | Frontiers in Immunology | 2021 | ISSN 1664-3224 |
| Jozic, Ivan et al. | Glucocorticoid-mediated induction of caveolin-1 disrupts cytoskeletal organization, inhibits cell migration and re-epithelialization of non-healing wounds | Communications Biology | 2021 | ISSN 2399-3642 |
| Salameh, Joëlle et al. | Cdc42 and its BORG2 and BORG3 effectors control the subcellular localization of septins between actin stress fibers and microtubules | Current Biology | 2021 | ISSN 1879-0445 |
| Lee, Daniel | miR‑769‑5p is associated with prostate cancer recurrence and modulates proliferation and apoptosis of cancer cells | Experimental and Therapeutic Medicine | 2021 | ISSN 1792--0981 |
| Novak, Caymen M. et al. | Compressive stimulation enhances ovarian cancer proliferation, invasion, chemoresistance, and mechanotransduction via cdc42 in a 3d bioreactor | Cancers | 2020 | ISSN 2072-6694 |
| Andrews, Madeline G. et al. | Mtor signaling regulates the morphology and migration of outer radial glia in developing human cortex | eLife | 2020 | ISSN 2050-084X |
| Reyes-Miguel, Tania et al. | CDC42 drives RHOA activity and actin polymerization during capacitation | Reproduction | 2020 | ISSN 1741-7899 |
| Wilson, Kitchener D. et al. | Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates | Developmental Cell | 2020 | ISSN 1878-1551 |
| Wu, Huijuan et al. | Progressive Pulmonary Fibrosis Is Caused by Elevated Mechanical Tension on Alveolar Stem Cells | Cell | 2020 | ISSN 1097-4172 |
| Zhang, Xiao et al. | Elevating EGFR-MAPK program by a nonconventional Cdc42 enhances intestinal epithelial survival and regeneration | JCI Insight | 2020 | ISSN 2379-3708 |
| Malek, Natalia et al. | Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) technique shows that non-muscle β and γ actin are not equal in relation to human melanoma cells’ motility and focal adhesion formation | International Journal of Molecular Sciences | 2020 | ISSN 1422-0067 |
| Choraghe, Rohan P. et al. | RHOA-mediated mechanical force generation through Dectin-1 | Journal of cell science | 2020 | ISSN 1477-9137 |
| Ursino, Gloria M et al. | ABCA12 regulates insulin secretion from β‐cells | EMBO reports | 2020 | ISSN 1469--221X |
| Gorisse, Laetitia et al. | Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42 | Journal of Biological Chemistry | 2020 | ISSN 1083-351X |
| Rong, Zhouyi et al. | Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aβ42 in triggering receptor expressed on myeloid cells 2 loss-of-function murine models | FASEB Journal | 2020 | ISSN 1530-6860 |
| Talamás-Lara, Daniel et al. | Entamoeba histolytica and Entamoeba dispar: Morphological and Behavioral Differences Induced by Fibronectin through GTPases Activation and Actin-Binding Proteins | The Journal of eukaryotic microbiology | 2020 | ISSN 1550--7408 |
| Krueger, Irena et al. | Reelin amplifies glycoprotein VI activation and alphaiib beta3 integrin outside-in signaling via PLC Gamma 2 and Rho GTPases | Arteriosclerosis, Thrombosis, and Vascular Biology | 2020 | ISSN 1524-4636 |
| Wu, Xuping et al. | Wnt5a induces ROR1 and ROR2 to activate RhoA in esophageal squamous cell carcinoma cells | Cancer Management and Research | 2019 | ISSN 1179-1322 |
| Zanin, Juan P. et al. | The p75NTR influences cerebellar circuit development and adult behavior via regulation of cell cycle duration of granule cell progenitors | Journal of Neuroscience | 2019 | ISSN 1529-2401 |
| Yan, Ting et al. | Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells | Journal of Biological Chemistry | 2018 | ISSN 1083-351X |
| Santhana Kumar, Karthiga et al. | TGF-β Determines the Pro-migratory Potential of bFGF Signaling in Medulloblastoma | Cell Reports | 2018 | ISSN 2211-1247 |
| Veluthakal, Rajakrishnan et al. | Restoration of glucose-stimulated Cdc42-PAK1 activation and insulin secretion by a selective Epac activator in type 2 diabetic human islets | Diabetes | 2018 | ISSN 1939-327X |
| Mayer, Louisa et al. | Nbeal2 interacts with Dock7, Sec16a, and Vac14 | Blood | 2018 | ISSN 1528-0020 |
| Suraneni, Praveen K. et al. | Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activity | Blood Advances | 2018 | ISSN 2473-9537 |
| Kim, Jongshin et al. | YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation | Journal of Clinical Investigation | 2017 | ISSN 1558-8238 |
| Ruggiero, Carmen et al. | Dosage-dependent regulation of VAV2 expression by steroidogenic factor-1 drives adrenocortical carcinoma cell invasion | Science Signaling | 2017 | ISSN 1937-9145 |
| Gu, Changkyu et al. | Dynamin autonomously regulates podocyte focal adhesion maturation | Journal of the American Society of Nephrology | 2017 | ISSN 1533-3450 |
| Jones, Eleanor L. et al. | Dendritic Cell Migration and Antigen Presentation Are Coordinated by the Opposing Functions of the Tetraspanins CD82 and CD37 | The Journal of Immunology | 2016 | ISSN 0022--1767 |
| Sroka, Jolanta et al. | Lamellipodia and membrane blebs drive efficient electrotactic migration of rat walker carcinosarcoma cells WC 256 | PLoS ONE | 2016 | ISSN 1932-6203 |
| Herrera-Martínez, Mayra et al. | Antiamoebic activity of Adenophyllum aurantium (L.) strother and its effect on the actin cytoskeleton of Entamoeba histolytica | Frontiers in Pharmacology | 2016 | ISSN 1663-9812 |
| Martins, Rui et al. | Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions | Nature Immunology | 2016 | ISSN 1529-2916 |
| Xiao, Bin et al. | Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling | Oncotarget | 2016 | ISSN 1949-2553 |
| Zhao, Chen Ze et al. | Inhibition of farnesyl pyrophosphate synthase improves pressure overload induced chronic cardiac remodeling | Scientific Reports | 2016 | ISSN 2045-2322 |
| Tien, Sui Chih et al. | The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42 | Nature Communications | 2016 | ISSN 2041-1723 |
| Breslin, Jerome W. et al. | Involvement of local lamellipodia in endothelial barrier function | PLoS ONE | 2015 | ISSN 1932-6203 |
| Guo, Yuna et al. | A novel pharmacologic activity of ketorolac for therapeutic benefit in ovarian cancer patients | Clinical Cancer Research | 2015 | ISSN 1557-3265 |
| Yan, Yi et al. | Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5 | Nature Communications | 2015 | ISSN 2041-1723 |
| Ochoa-Alvarez, Jhon A. et al. | Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanisms | Oncotarget | 2015 | ISSN 1949-2553 |
| Hanin, Geula et al. | Competing targets of microRNA-608 affect anxiety and hypertension | Human Molecular Genetics | 2014 | ISSN 1460-2083 |
| Rigano, Luciano A. et al. | Listeria monocytogenes antagonizes the human GTPase Cdc42 to promote bacterial spread | Cellular Microbiology | 2014 | ISSN 1462-5822 |
| Chakravarti, Bandana et al. | Thioaryl naphthylmethanone oxime ether analogs as novel anticancer agents | Journal of Medicinal Chemistry | 2014 | ISSN 1520-4804 |
| Ahn, Bum Ju et al. | Ninjurin1 enhances the basal motility and transendothelial migration of immune cells by inducing protrusive membrane dynamics | Journal of Biological Chemistry | 2014 | ISSN 1083-351X |
| Kalia, Manjula et al. | Japanese Encephalitis Virus Infects Neuronal Cells through a Clathrin-Independent Endocytic Mechanism | Journal of Virology | 2013 | ISSN 0022--538X |
| Barrio, Laura et al. | TLR4 Signaling Shapes B Cell Dynamics via MyD88-Dependent Pathways and Rac GTPases | The Journal of Immunology | 2013 | ISSN 0022--1767 |
| Valtcheva, Nadejda et al. | The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42 | Journal of Biological Chemistry | 2013 | ISSN 0021-9258 |
| Dubash, Adi D. et al. | The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1 | Journal of Cell Biology | 2013 | ISSN 0021-9525 |
| Ramsay, Alan G. et al. | Chronic lymphocytic leukemia cells induce defective LFA-1-directed T-cell motility by altering Rho GTPase signaling that is reversible with lenali****** | Blood | 2013 | ISSN 1528-0020 |
| Yao, Honghong et al. | Nonmuscle myosin light-chain kinase mediates microglial migration induced by HIV Tat: involvement of β1 integrins | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 2013 | ISSN 1530--6860 |
| Chen, Bin et al. | Alteration of mevalonate pathway related enzyme expressions in pressure overload-induced cardiac hypertrophy and associated heart failure with preserved ejection fraction | Cellular Physiology and Biochemistry | 2013 | ISSN 1421-9778 |
| Bray, Kristi et al. | Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration | Breast Cancer Research | 2013 | ISSN 1465-5411 |
| Yang, Jian et al. | Cardiac-specific overexpression of farnesyl pyrophosphate synthase induces cardiac hypertrophy and dysfunction in mice | Cardiovascular Research | 2013 | ISSN 0008-6363 |
| Dhaliwal, Anandika et al. | Cellular Cytoskeleton Dynamics Modulates Non-Viral Gene Delivery through RhoGTPases | 2012 | PMID 22509380 | |
| Chen, Guang et al. | Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells (Journal of Biological Chemistry (2012) 2 | Journal of Biological Chemistry | 2012 | ISSN 0021-9258 |
| Chen, Si Meng et al. | Inhibition of tumor cell growth, proliferation and migration by X-387, a novel active-site inhibitor of mTOR | Biochemical Pharmacology | 2012 | ISSN 0006-2952 |
| Martin-Granados, Cristina et al. | A role for PP1/NIPP1 in steering migration of human cancer cells | PLoS ONE | 2012 | ISSN 1932-6203 |
| Elali, Ayman et al. | Liver X receptor activation enhances blood-brain barrier integrity in the ischemic brain and increases the abundance of ATP-binding cassette transporters ABCB1 and ABCC1 on brain capillary cells | Brain Pathology | 2012 | ISSN 1015-6305 |
| Eggers, Carrie M. et al. | STE20-related kinase adaptor protein α (STRADα) regulates cell polarity and invasion through PAK1 signaling in LKB1-null cells | The Journal of biological chemistry | 2012 | ISSN 1083--351X |
| Ramsay, Alan G. et al. | Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenali******: Establishing a reversible immune evasion mechanism in human cancer | Blood | 2012 | ISSN 1528-0020 |
| Lichtenstein, Mathieu P. et al. | Secretase-independent and RhoGTPase/PAK/ERK-dependent regulation of cytoskeleton dynamics in astrocytes by NSAIDs and derivatives | Journal of Alzheimer's disease : JAD | 2010 | ISSN 1875--8908 |
| Stankiewicz, Traci E. et al. | GTPase activating protein function of p85 facilitates uptake and recycling of the β1 integrin | Biochemical and biophysical research communications | 2010 | ISSN 0006-291X |
| Romero, Ana M. et al. | Chronic ethanol exposure alters the levels, assembly, and cellular organization of the actin cytoskeleton and microtubules in hippocampal neurons in primary culture | Toxicological Sciences | 2010 | ISSN 1096-6080 |
| McHenry, Peter R. et al. | P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis | Breast Cancer Research | 2010 | ISSN 1465-5411 |
| Heckman-Stoddard, Brandy M. et al. | Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression | 2009 | ISSN 1465-5411 | |
| Schlegel, Nicolas et al. | Impaired cAMP and Rac 1 signaling contribute to TNF-alpha-induced endothelial barrier breakdown in microvascular endothelium | Microcirculation (New York, N.Y. : 1994) | 2009 | ISSN 1549--8719 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Phuyal, Santosh et al. | Mechanical strain stimulates COPII-dependent secretory trafficking via Rac1 | The EMBO Journal | 2022 | ISSN 1460--2075 |
| Nath, Anu S. et al. | Modulation of the cell membrane lipid milieu by peroxisomal β-oxidation induces Rho1 signaling to trigger inflammatory responses | Cell Reports | 2022 | ISSN 2211-1247 |
| Garitano-Trojaola, Andoni et al. | Actin cytoskeleton deregulation confers midostaurin resistance in FLT3-mutant acute myeloid leukemia | Communications biology | 2021 | ISSN 2399-3642 |
| Turgu, Busra et al. | HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner | Oncogene | 2021 | ISSN 1476-5594 |
| Crawford, Melissa et al. | Essential Role for Integrin-Linked Kinase in Melanoblast Colonization of the Skin | Journal of Investigative Dermatology | 2020 | ISSN 1523-1747 |
| Berthenet, Kevin et al. | Failed Apoptosis Enhances Melanoma Cancer Cell Aggressiveness | Cell Reports | 2020 | ISSN 2211-1247 |
| Zhu, Bili et al. | Lipid oversupply induces CD36 sarcolemmal translocation via dual modulation of PKCζ and TBC1D1: An early event prior to insulin resistance | Theranostics | 2020 | ISSN 1838-7640 |
| El-Naggar, Amal M. et al. | HACE1 is a potential tumor suppressor in osteosarcoma | Cell Death and Disease | 2019 | ISSN 2041-4889 |
| Elshaer, Sally L. et al. | Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinal vascular permeability in mice via inhibition of inflammation and the RhoA kinase pathway | Diabetologia | 2019 | ISSN 1432-0428 |
| Yan, Ting et al. | Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells | Journal of Biological Chemistry | 2018 | ISSN 1083-351X |
| Kang, Jeong Hun et al. | Protein kinase Cα as a therapeutic target in cancer | Protein Kinase C: Emerging Roles and Therapeutic Potential | 2018 | Article Link |
| Kai, Masahiro et al. | Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancer | Molecular Carcinogenesis | 2017 | ISSN 1098-2744 |
| Kim, Jongshin et al. | YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation | Journal of Clinical Investigation | 2017 | ISSN 1558-8238 |
| Ruggiero, Carmen et al. | Dosage-dependent regulation of VAV2 expression by steroidogenic factor-1 drives adrenocortical carcinoma cell invasion | Science Signaling | 2017 | ISSN 1937-9145 |
| Jeong, Suk Yeong et al. | Loss of Tpm4.1 leads to disruption of cell-cell adhesions and invasive behavior in breast epithelial cells via increased Rac1 signaling | Oncotarget | 2017 | ISSN 1949-2553 |
| Sylow, Lykke et al. | Rac1 governs exercise-stimulated glucose uptake in skeletal muscle through regulation of GLUT4 translocation in mice | Journal of Physiology | 2016 | ISSN 1469-7793 |
| Sarowar, Tasnuva et al. | Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2 | Molecular Brain | 2016 | ISSN 1756-6606 |
| Thuault, Sylvie et al. | The RhoE/ROCK/ARHGAP25 signaling pathway controls cell invasion by inhibition of Rac activity | Molecular Biology of the Cell | 2016 | ISSN 1939-4586 |
| Yan, Yi et al. | Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5 | Nature Communications | 2015 | ISSN 2041-1723 |
| Reyes-Reyes, E. Merit et al. | Mechanistic studies of anticancer aptamer AS1411 reveal a novel role for nucleolin in regulating Rac1 activation | Molecular Oncology | 2015 | ISSN 1878-0261 |
| Marchesin, Valentina et al. | ARF6 promotes the formation of Rac1 and WAVE-dependent ventral F-Actin rosettes in breast cancer cells in response to epidermal growth factor | PLoS ONE | 2015 | ISSN 1932-6203 |
| Nakajima, Chikako et al. | The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development | Development (Cambridge) | 2014 | ISSN 1477-9129 |
| Sylow, Lykke et al. | Rac1 - a novel regulator of contraction-stimulated glucose uptake in skeletal muscle | Experimental Physiology | 2014 | ISSN 1469-445X |
| Radeva, Mariya Y. et al. | PKA compartmentalization via AKAP220 and AKAP12 contributes to endothelial barrier regulation | PLoS ONE | 2014 | ISSN 1932-6203 |
| Redhu, Naresh Singh et al. | Thymic stromal lymphopoietin induces migration in human airway smooth muscle cells | Scientific Reports | 2013 | ISSN 2045-2322 |
| Bray, Kristi et al. | Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration | Breast Cancer Research | 2013 | ISSN 1465-5411 |
| Kikuchi, K. et al. | Protein kinase C iota as a therapeutic target in alveolar rhabdomyosarcoma | Oncogene | 2013 | ISSN 1476--5594 |
| Sylow, Lykke et al. | Rac1 signaling is required for insulin-stimulated glucose uptake and is dysregulated in insulin-resistant murine and human skeletal muscle | Diabetes | 2013 | ISSN 0012-1797 |
| Sayedyahossein, Samar et al. | Essential role of integrin-linked kinase in regulation of phagocytosis in keratinocytes | FASEB Journal | 2012 | ISSN 1530-6860 |
| Eggers, Carrie M. et al. | STE20-related kinase adaptor protein α (STRADα) regulates cell polarity and invasion through PAK1 signaling in LKB1-null cells | The Journal of biological chemistry | 2012 | ISSN 1083--351X |
| Binker, Marcelo G. et al. | TGF-β1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-κB/IL-6/MMP-2 | Biochemical and biophysical research communications | 2011 | ISSN 1090--2104 |
| Vives, Virginie et al. | The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts | 2011 | ISSN 1523--4681 | |
| Kigel, Boaz et al. | Plexin-A4 promotes tumor progression and tumor angiogenesis by enhancement of VEGF and bFGF signaling | Blood | 2011 | ISSN 1528-0020 |
| Johanna, Gutiérrez Vargas et al. | Rac1 activity changes are associated with neuronal pathology and spatial memory long-term recovery after global cerebral ischemia | Neurochemistry international | 2010 | ISSN 1872--9754 |
| Kamai, Takao et al. | Increased Rac1 activity and Pak1 overexpression are associated with lymphovascular invasion and lymph node metastasis of upper urinary tract cancer | BMC Cancer | 2010 | ISSN 1471-2407 |
| McHenry, Peter R. et al. | P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis | Breast Cancer Research | 2010 | ISSN 1465-5411 |
| Baumer, Y. et al. | Role of Rac 1 and cAMP in endothelial barrier stabilization and thrombin-induced barrier breakdown | Journal of Cellular Physiology | 2009 | ISSN 1097--4652 |
| Heckman-Stoddard, Brandy M. et al. | Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression | 2009 | ISSN 1465-5411 | |
| Chastre, Eric et al. | TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasiveness | The FASEB Journal | 2009 | ISSN 1530--6860 |
| Ramirez, Servio H. et al. | Activation of Peroxisome Proliferator-Activated Receptor γ (PPARγ) Suppresses Rho GTPases in Human Brain Microvascular Endothelial Cells and Inhibits Adhesion and Transendothelial Migration of HIV-1 Infected Monocytes | The Journal of Immunology | 2008 | ISSN 0022--1767 |
| Petroll, W. Matthew et al. | Dynamic assessment of fibroblast mechanical activity during rac-induced cell spreading in 3-D culture | Journal of Cellular Physiology | 2008 | ISSN 0021-9541 |
| Moniz, Sónia et al. | WNK2 modulates MEK1 activity through the Rho GTPase pathway | Cellular signalling | 2008 | ISSN 0898--6568 |
| Pontow, Suzanne et al. | Antiviral Activity of a Rac GEF inhibitor Characterized with a Sensitive HIV/SIV Fusion Assay | Virology | 2007 | ISSN 0042-6822 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Darp, Revati et al. | Oncogenic BRAF induces whole-genome doubling through suppression of cytokinesis | Nature Communications 2022 13:1 | 2022 | ISSN 2041--1723 |
| Francis, Caitlin R. et al. | Rab35 governs apicobasal polarity through regulation of actin dynamics during sprouting angiogenesis | Nature Communications 2022 13:1 | 2022 | ISSN 2041--1723 |
| Kim, Seunghoon et al. | Investigating the Anti-Inflammatory Effects of RCI001 for Treating Ocular Surface Diseases: Insight Into the Mechanism of Action | Frontiers in Immunology | 2022 | |
| Sugisawa, Erika et al. | Nociceptor-derived Reg3γ prevents endotoxic death by targeting kynurenine pathway in microglia | Cell Reports | 2022 | ISSN 2211-1247 |
| Borza, Corina M. et al. | The Collagen Receptor Discoidin Domain Receptor 1b Enhances Integrin β1-Mediated Cell Migration by Interacting With Talin and Promoting Rac1 Activation | Frontiers in Cell and Developmental Biology | 2022 | Article Link |
| Kim, Seunghoon et al. | Investigating the Anti-Inflammatory Effects of RCI001 for Treating Ocular Surface Diseases: Insight Into the Mechanism of Action | Frontiers in Immunology | 2022 | ISSN 1664-3224 |
| Harms, Julia et al. | Pals1 functions in redundancy with SMAP1 to inhibit Arf6 in order to prevent Rac1-dependent colorectal cancer cell migration and invasion | Cancer Gene Therapy 2022 | 2022 | ISSN 1476--5500 |
| Ma, Shang et al. | A role of PIEZO1 in iron metabolism in mice and humans | Cell | 2021 | ISSN 1097-4172 |
| Gurusamy, Malarvizhi et al. | G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators | Nature Communications | 2021 | ISSN 2041-1723 |
| Kinsella, Sinéad et al. | Attenuation of apoptotic cell detection triggers thymic regeneration after damage | Cell Reports | 2021 | ISSN 2211-1247 |
| Vallejo, Daniela et al. | Wnt5a modulates dendritic spine dynamics through the regulation of Cofilin via small Rho GTPase activity in hippocampal neurons | Journal of Neurochemistry | 2021 | ISSN 1471-4159 |
| Ma, Yuanyuan et al. | Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during tooth root development | Development (Cambridge) | 2021 | ISSN 1477-9129 |
| Wegscheid, Michelle L. et al. | Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesis | Cell Reports | 2021 | ISSN 2211-1247 |
| Merlin, Johanna et al. | Non-canonical glutamine transamination sustains efferocytosis by coupling redox buffering to oxidative phosphorylation | Nature Metabolism | 2021 | ISSN 2522-5812 |
| Mao, De Yu et al. | CLIC1 and CLIC4 mediate endothelial S1P receptor signaling to facilitate Rac1 and RhoA activity and function | Science Signaling | 2021 | ISSN 1937-9145 |
| Andrews, Madeline G. et al. | Mtor signaling regulates the morphology and migration of outer radial glia in developing human cortex | eLife | 2020 | ISSN 2050-084X |
| Choraghe, Rohan P. et al. | RHOA-mediated mechanical force generation through Dectin-1 | Journal of cell science | 2020 | ISSN 1477-9137 |
| Sheftel, Celeste M. et al. | Serotonin stimulated parathyroid hormone related protein induction in the mammary epithelia by transglutaminase-dependent serotonylation | PLoS ONE | 2020 | ISSN 1932-6203 |
| Angé, Marine et al. | α1AMP-Activated Protein Kinase Protects against Lipopolysaccharide-Induced Endothelial Barrier Disruption via Junctional Reinforcement and Activation of the p38 MAPK/HSP27 Pathway | International Journal of Molecular Sciences | 2020 | ISSN 1422-0067 |
| Szrejder, Maria et al. | Metformin reduces TRPC6 expression through AMPK activation and modulates cytoskeleton dynamics in podocytes under diabetic conditions | Biochimica et Biophysica Acta - Molecular Basis of Disease | 2020 | ISSN 1879-260X |
| Wilson, Kitchener D. et al. | Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates | Developmental Cell | 2020 | ISSN 1878-1551 |
| Baker, Martin J. et al. | P-REX1-independent, calcium-dependent RAC1 hyperactivation in prostate cancer | Cancers | 2020 | ISSN 2072-6694 |
| Chen, Guo Ping et al. | Geranylgeranyl Transferase-I Knockout Inhibits Oxidative Injury of Vascular Smooth Muscle Cells and Attenuates Diabetes-Accelerated Atherosclerosis | Journal of Diabetes Research | 2020 | ISSN 2314-6753 |
| Woida, Patrick J. et al. | The Vibrio cholerae MARTX toxin silences the inflammatory response to cytoskeletal damage before inducing actin cytoskeleton collapse | Science Signaling | 2020 | ISSN 1937-9145 |
| Larribère, Lionel et al. | NF1-RAC1 axis regulates migration of the melanocytic lineage | Translational Oncology | 2020 | ISSN 1936-5233 |
| Kowluru, Renu A. | Retinopathy in a diet-induced type 2 diabetic rat model and role of epigenetic modifications | Diabetes | 2020 | ISSN 1939-327X |
| Malek, Natalia et al. | Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) technique shows that non-muscle β and γ actin are not equal in relation to human melanoma cells’ motility and focal adhesion formation | International Journal of Molecular Sciences | 2020 | ISSN 1422-0067 |
| Krueger, Irena et al. | Reelin amplifies glycoprotein VI activation and alphaiib beta3 integrin outside-in signaling via PLC Gamma 2 and Rho GTPases | Arteriosclerosis, Thrombosis, and Vascular Biology | 2020 | ISSN 1524-4636 |
| Rong, Zhouyi et al. | Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aβ42 in triggering receptor expressed on myeloid cells 2 loss-of-function murine models | FASEB Journal | 2020 | ISSN 1530-6860 |
| Zanin, Juan P. et al. | The p75NTR influences cerebellar circuit development and adult behavior via regulation of cell cycle duration of granule cell progenitors | Journal of Neuroscience | 2019 | ISSN 1529-2401 |
| Shi, Wei et al. | EPHB6 controls catecholamine biosynthesis by up-regulating tyrosine hydroxylase transcription in adrenal gland chromaffin cells | Journal of Biological Chemistry | 2019 | ISSN 1083-351X |
| Gokoffski, Kimberly K. et al. | Physiologic electrical fields direct retinal ganglion cell axon growth in vitro | Investigative Ophthalmology and Visual Science | 2019 | ISSN 1552-5783 |
| Wang, Baomei et al. | Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced Colitis | Cell Reports | 2019 | ISSN 2211-1247 |
| Soni, Upendra Kumar et al. | A high level of TGF-B1 promotes endometriosis development via cell migration, adhesiveness, colonization, and invasiveness | Biology of Reproduction | 2019 | ISSN 1529-7268 |
| Laufer, Julia M. et al. | Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation | Cell Reports | 2019 | ISSN 2211-1247 |
| Stefanelli, Victoria L. et al. | Citrullination of fibronectin alters integrin clustering and focal adhesion stability promoting stromal cell invasion | Matrix Biology | 2019 | ISSN 1569-1802 |
| Wu, Wenjuan et al. | Inhibition of Rac1-dependent forgetting alleviates memory deficits in animal models of Alzheimer’s disease | Protein and Cell | 2019 | ISSN 1674-8018 |
| Haq, Naila et al. | Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neurons | PLoS Biology | 2019 | ISSN 1545-7885 |
| De Bessa, Tiphany Coralie et al. | Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRas | Cell Death and Disease | 2019 | ISSN 2041-4889 |
| Saito-Reis, Chelsea A. et al. | The tetraspanin CD82 regulates bone marrow homing and engraftment of hematopoietic stem and progenitor cells | Molecular Biology of the Cell | 2018 | ISSN 1939-4586 |
| Rachubik, Patrycja et al. | The TRPC6-AMPK pathway is involved in insulin-dependent cytoskeleton reorganization and glucose uptake in cultured rat podocytes | Cellular Physiology and Biochemistry | 2018 | ISSN 1421-9778 |
| Santhana Kumar, Karthiga et al. | TGF-β Determines the Pro-migratory Potential of bFGF Signaling in Medulloblastoma | Cell Reports | 2018 | ISSN 2211-1247 |
| Suraneni, Praveen K. et al. | Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activity | Blood Advances | 2018 | ISSN 2473-9537 |
| Caggia, Silvia et al. | Novel role of Giα2 in cell migration: Downstream of PI3-kinase–AKT and Rac1 in prostate cancer cells | Journal of Cellular Physiology | 2018 | ISSN 1097-4652 |
| Duraisamy, Arul J. et al. | Epigenetics and regulation of oxidative stress in diabetic retinopathy | Investigative Ophthalmology and Visual Science | 2018 | ISSN 1552-5783 |
| Olabi, Safiah et al. | Integrin-Rac signalling for mammary epithelial stem cell self-renewal 06 Biological Sciences 0601 Biochemistry and Cell Biology | Breast Cancer Research | 2018 | ISSN 1465-542X |
| Mayer, Louisa et al. | Nbeal2 interacts with Dock7, Sec16a, and Vac14 | Blood | 2018 | ISSN 1528-0020 |
| Stierwalt, Harrison D. et al. | Insulin-stimulated Rac1-GTP binding is not impaired by palmitate treatment in L6 myotubes | Physiological Reports | 2018 | ISSN 2051-817X |
| Proto, Jonathan D. et al. | Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution | Immunity | 2018 | ISSN 1097-4180 |
| Dyberg, Cecilia et al. | Rho-associated kinase is a therapeutic target in neuroblastoma | Proceedings of the National Academy of Sciences of the United States of America | 2017 | ISSN 1091-6490 |
| Hendricks, Louie et al. | Milk fat globule-epidermal growth factor-factor VIII–derived peptide MSP68 is a cytoskeletal immunomodulator of neutrophils that inhibits Rac1 | Journal of Surgical Research | 2017 | ISSN 1095-8673 |
| Moreno-Layseca, Paulina et al. | The requirement of integrins for breast epithelial proliferation | European Journal of Cell Biology | 2017 | ISSN 1618-1298 |
| Kumar, Vijay et al. | Integrin beta8 (ITGB8) activates VAV-RAC1 signaling via FAK in the acquisition of endometrial epithelial cell receptivity for blastocyst implantation | Scientific Reports | 2017 | ISSN 2045-2322 |
| Ubba, Vaibhave et al. | RHOG-DOCK1-RAC1 Signaling Axis Is Perturbed in DHEA-Induced Polycystic Ovary in Rat Model | Reproductive Sciences | 2017 | ISSN 1933-7205 |
| Chen, Guo Ping et al. | Inhibition of farnesyl pyrophosphate synthase attenuates high glucose-induced vascular smooth muscle cells proliferation | Molecular Medicine Reports | 2017 | ISSN 1791-3004 |
| Gu, Changkyu et al. | Dynamin autonomously regulates podocyte focal adhesion maturation | Journal of the American Society of Nephrology | 2017 | ISSN 1533-3450 |
| Baranov, Maksim V. et al. | SWAP70 Organizes the Actin Cytoskeleton and Is Essential for Phagocytosis | Cell Reports | 2016 | ISSN 2211-1247 |
| Valdez, Chris M. et al. | The Rac-GAP alpha2-chimaerin regulates hippocampal dendrite and spine morphogenesis | Molecular and Cellular Neuroscience | 2016 | ISSN 1095-9327 |
| Sayyad, Wasim A. et al. | The role of Rac1 in the growth cone dynamics and force generation of DRG neurons | PLoS ONE | 2016 | ISSN 1932-6203 |
| Lampi, Marsha C. et al. | Simvastatin ameliorates matrix stiffness-mediated endothelial monolayer disruption | PLoS ONE | 2016 | ISSN 1932-6203 |
| Jones, Eleanor L. et al. | Dendritic Cell Migration and Antigen Presentation Are Coordinated by the Opposing Functions of the Tetraspanins CD82 and CD37 | The Journal of Immunology | 2016 | ISSN 0022--1767 |
| Zhao, Chen Ze et al. | Inhibition of farnesyl pyrophosphate synthase improves pressure overload induced chronic cardiac remodeling | Scientific Reports | 2016 | ISSN 2045-2322 |
| Sroka, Jolanta et al. | Lamellipodia and membrane blebs drive efficient electrotactic migration of rat walker carcinosarcoma cells WC 256 | PLoS ONE | 2016 | ISSN 1932-6203 |
| Rom, Slava et al. | PARP inhibition in leukocytes diminishes inflammation via effects on integrins/cytoskeleton and protects the blood-brain barrier | Journal of Neuroinflammation | 2016 | ISSN 1742-2094 |
| Hamers, Anouk A.J. et al. | Nur77-deficiency in bone marrow-derived macrophages modulates inflammatory responses, extracellular matrix homeostasis, phagocytosis and tolerance | BMC Genomics | 2016 | ISSN 1471-2164 |
| Xiao, Bin et al. | Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling | Oncotarget | 2016 | ISSN 1949-2553 |
| Herberich, Stefanie E. et al. | ANKS1B Interacts with the cerebral cavernous malformation protein-1 and controls endothelial permeability but not sprouting angiogenesis | PLoS ONE | 2015 | ISSN 1932-6203 |
| Caution, Kyle et al. | Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance | Scientific Reports | 2015 | ISSN 2045-2322 |
| Ochoa-Alvarez, Jhon A. et al. | Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanisms | Oncotarget | 2015 | ISSN 1949-2553 |
| Rom, Slava et al. | Poly(ADP-ribose) polymerase-1 inhibition in brain endothelium protects the blood-brain barrier under physiologic and neuroinflammatory conditions | Journal of Cerebral Blood Flow and Metabolism | 2015 | ISSN 1559-7016 |
| Zeineddine, Rafaa et al. | SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation | Molecular Neurodegeneration | 2015 | ISSN 1750-1326 |
| Guo, Yuna et al. | A novel pharmacologic activity of ketorolac for therapeutic benefit in ovarian cancer patients | Clinical Cancer Research | 2015 | ISSN 1557-3265 |
| Rom, Slava et al. | The dual action of poly(ADP-ribose) polymerase -1 (PARP-1) inhibition in HIV-1 infection: HIV-1 ltr inhibition and diminution in Rho GTPase activity | Frontiers in Microbiology | 2015 | ISSN 1664-302X |
| Breslin, Jerome W. et al. | Involvement of local lamellipodia in endothelial barrier function | PLoS ONE | 2015 | ISSN 1932-6203 |
| Rigano, Luciano A. et al. | Listeria monocytogenes antagonizes the human GTPase Cdc42 to promote bacterial spread | Cellular Microbiology | 2014 | ISSN 1462-5822 |
| Maurya, Vineet Kumar et al. | Expression and activity of Rac1 is negatively affected in the dehydroepiandrosterone induced polycystic ovary of mouse | Journal of Ovarian Research | 2014 | ISSN 1757-2215 |
| Marinković, Goran et al. | Inhibition of GTPase Rac1 in Endothelium by 6-Mercaptopurine Results in Immunosuppression in Nonimmune Cells: New Target for an Old Drug | The Journal of Immunology | 2014 | ISSN 0022--1767 |
| Mackay, Joanna L. et al. | Simultaneous and independent tuning of RhoA and Rac1 activity with orthogonally inducible promoters | Integrative Biology (United Kingdom) | 2014 | ISSN 1757-9708 |
| Aguilar, Helena et al. | VAV3 mediates resistance to breast cancer endocrine therapy | Breast Cancer Research | 2014 | ISSN 1465-542X |
| Marinković, Goran et al. | 6-mercaptopurine reduces macrophage activation and gut epithelium proliferation through inhibition of GTPase Rac1 | Inflammatory Bowel Diseases | 2014 | ISSN 1536-4844 |
| Dubash, Adi D. et al. | The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1 | Journal of Cell Biology | 2013 | ISSN 0021-9525 |
| Yang, Jian et al. | Cardiac-specific overexpression of farnesyl pyrophosphate synthase induces cardiac hypertrophy and dysfunction in mice | Cardiovascular Research | 2013 | ISSN 0008-6363 |
| Buranda, Tione et al. | Rapid parallel flow cytometry assays of active GTPases using effector beads | Analytical Biochemistry | 2013 | ISSN 1096-0309 |
| Kalia, Manjula et al. | Japanese Encephalitis Virus Infects Neuronal Cells through a Clathrin-Independent Endocytic Mechanism | Journal of Virology | 2013 | ISSN 0022--538X |
| Papke, Christina L. et al. | Smooth muscle hyperplasia due to loss of smooth muscle α-actin is driven by activation of focal adhesion kinase, altered p53 localization and increased levels of platelet-derived growth factor receptor-β | Human Molecular Genetics | 2013 | ISSN 0964-6906 |
| Rom, Slava et al. | Selective activation of cannabinoid receptor 2 in leukocytes suppresses their engagement of the brain endothelium and protects the blood-brain barrier | American Journal of Pathology | 2013 | ISSN 0002-9440 |
| Ramsay, Alan G. et al. | Chronic lymphocytic leukemia cells induce defective LFA-1-directed T-cell motility by altering Rho GTPase signaling that is reversible with lenali****** | Blood | 2013 | ISSN 1528-0020 |
| Chen, Bin et al. | Alteration of mevalonate pathway related enzyme expressions in pressure overload-induced cardiac hypertrophy and associated heart failure with preserved ejection fraction | Cellular Physiology and Biochemistry | 2013 | ISSN 1421-9778 |
| Chen, Guang et al. | Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells (Journal of Biological Chemistry (2012) 2 | Journal of Biological Chemistry | 2012 | ISSN 0021-9258 |
| Sánchez, Elena G. et al. | African swine fever virus uses macropinocytosis to enter host cells | PLoS Pathogens | 2012 | ISSN 1553-7374 |
| Antonov, Alexander S. et al. | Regulation of endothelial barrier function by TGF-β type I receptor ALK5: potential role of contractile mechanisms and heat shock protein 90 | Journal of cellular physiology | 2012 | ISSN 1097--4652 |
| Greco, Carolina M. et al. | Chemotactic effect of prorenin on human aortic smooth muscle cells: a novel function of the (pro)renin receptor | Cardiovascular Research | 2012 | ISSN 0008--6363 |
| Ramsay, Alan G. et al. | Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenali******: Establishing a reversible immune evasion mechanism in human cancer | Blood | 2012 | ISSN 1528-0020 |
| Oshikawa, Jin et al. | Novel role of p66Shc in ROS-dependent VEGF signaling and angiogenesis in endothelial cells | American Journal of Physiology - Heart and Circulatory Physiology | 2012 | ISSN 0363-6135 |
| Arpaia, E. et al. | The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk | Oncogene | 2012 | ISSN 0950-9232 |
| Montalvo-Ortiz, Brenda L. et al. | Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase | The Journal of biological chemistry | 2012 | ISSN 1083--351X |
| Chen, Si Meng et al. | Inhibition of tumor cell growth, proliferation and migration by X-387, a novel active-site inhibitor of mTOR | Biochemical Pharmacology | 2012 | ISSN 0006-2952 |
| Stefanini, Lucia et al. | Rap1-Rac1 circuits potentiate platelet activation | Arteriosclerosis, thrombosis, and vascular biology | 2012 | ISSN 1524--4636 |
| Rom, Slava et al. | Glycogen synthase kinase 3β inhibition prevents monocyte migration across brain endothelial cells via Rac1-GTPase suppression and down-regulation of active integrin conformation | American Journal of Pathology | 2012 | ISSN 0002-9440 |
| Vives, Virginie et al. | The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts | 2011 | ISSN 1523--4681 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Talwar, Shefali et al. | Mechanosensitive smooth muscle cell phenotypic plasticity emerging from a null state and the balance between Rac and Rho | Cell Reports | 2021 | ISSN 2211-1247 |
| Lagresle-Peyrou, Chantal et al. | A gain-of-function RAC2 mutation is associated with bone marrow hypoplasia and an autosomal dominant form of severe combined immunodeficiency | Haematologica | 2021 | ISSN 1592-8721 |
| Talamás-Lara, Daniel et al. | Entamoeba histolytica and Entamoeba dispar: Morphological and Behavioral Differences Induced by Fibronectin through GTPases Activation and Actin-Binding Proteins | The Journal of eukaryotic microbiology | 2020 | ISSN 1550--7408 |
| Cash, Jennifer N. et al. | Discovery of small molecules that target the phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent Rac exchanger 1 (P-Rex1) PIP3-binding site and inhibit p-Rex1-dependent functions in neutrophils | Molecular Pharmacology | 2020 | ISSN 1521-0111 |
| Wu, Xuping et al. | Wnt5a induces ROR1 and ROR2 to activate RhoA in esophageal squamous cell carcinoma cells | Cancer Management and Research | 2019 | ISSN 1179-1322 |
| Tsitsilashvili, Elene et al. | Myelin basic protein charge isomers change macrophage polarization | Journal of inflammation research | 2019 | ISSN 1178--7031 |
| Roman-Garcia, Sara et al. | Distinct roles for Bruton's Tyrosine Kinase in B cell immune synapse formation | Frontiers in Immunology | 2018 | ISSN 1664-3224 |
| Hu, Shuling et al. | Mesenchymal Stem Cell Microvesicles Restore Protein Permeability Across Primary Cultures of Injured Human Lung Microvascular Endothelial Cells | Stem cells translational medicine | 2018 | ISSN 2157--6564 |
| Herrera-Martínez, Mayra et al. | Antiamoebic activity of Adenophyllum aurantium (L.) strother and its effect on the actin cytoskeleton of Entamoeba histolytica | Frontiers in Pharmacology | 2016 | ISSN 1663-9812 |
| Güntert, Tanja et al. | Temporal Rac1 - HIF-1 crosstalk modulates hypoxic survival of aged neurons | Brain Research | 2016 | ISSN 1872-6240 |
| Chen, Lihua et al. | Smooth muscle-alpha actin inhibits vascular smooth muscle cell proliferation and migration by inhibiting rac1 activity | PLoS ONE | 2016 | ISSN 1932-6203 |
| Ahn, Bum Ju et al. | Ninjurin1 enhances the basal motility and transendothelial migration of immune cells by inducing protrusive membrane dynamics | Journal of Biological Chemistry | 2014 | ISSN 1083-351X |
| Kalia, Manjula et al. | Japanese Encephalitis Virus Infects Neuronal Cells through a Clathrin-Independent Endocytic Mechanism | Journal of Virology | 2013 | ISSN 0022--538X |
| Teplova, Irina et al. | ATG proteins mediate efferocytosis and suppress inflammation in mammary involution | Autophagy | 2013 | ISSN 1554-8635 |
| Barrio, Laura et al. | TLR4 Signaling Shapes B Cell Dynamics via MyD88-Dependent Pathways and Rac GTPases | The Journal of Immunology | 2013 | ISSN 0022--1767 |
| Ninkovi, Jana et al. | Morphine decreases bacterial phagocytosis by inhibiting actin polymerization through cAMP-, Rac-1-, and p38 MAPK-dependent mechanisms | American Journal of Pathology | 2012 | ISSN 0002-9440 |
| Dhaliwal, Anandika et al. | Cellular Cytoskeleton Dynamics Modulates Non-Viral Gene Delivery through RhoGTPases | 2012 | PMID 22509380 | |
| Ridgway, Lon D. et al. | Heparanase-induced GEF-H1 signaling regulates the cytoskeletal dynamics of brain metastatic breast cancer cells | Molecular Cancer Research | 2012 | ISSN 1541-7786 |
| Halpert, Michal et al. | Rac-dependent doubling of HeLa cell area and impairment of cell migration and cell cycle by compounds from Iris germanica | Protoplasma | 2011 | ISSN 0033-183X |
| May, James M. | The SLC23 family of ascorbate transporters: ensuring that you get and keep your daily dose of vitamin C | British Journal of Pharmacology | 2011 | ISSN 0007-1188 |
| Vives, Virginie et al. | The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts | 2011 | ISSN 1523--4681 | |
| Johanna, Gutiérrez Vargas et al. | Rac1 activity changes are associated with neuronal pathology and spatial memory long-term recovery after global cerebral ischemia | Neurochemistry international | 2010 | ISSN 1872--9754 |
| Fang, Xiaohui et al. | Allogeneic human mesenchymal stem cells restore epithelial protein permeability in cultured human alveolar type II cells by secretion of angiopoietin-1 | Journal of Biological Chemistry | 2010 | ISSN 0021-9258 |
| Romero, Ana M. et al. | Chronic ethanol exposure alters the levels, assembly, and cellular organization of the actin cytoskeleton and microtubules in hippocampal neurons in primary culture | Toxicological Sciences | 2010 | ISSN 1096-6080 |
| Zhu, Jianxin et al. | P21-Activated Kinases Regulate Actin Remodeling in Glomerular Podocytes | American Journal of Physiology - Renal Physiology | 2010 | ISSN 0363-6127 |
| Ridgway, Lon D. et al. | Modulation of GEF-H1 Induced Signaling by Heparanase in Brain Metastatic Melanoma Cells | Journal of cellular biochemistry | 2010 | ISSN 0730-2312 |
| Lichtenstein, Mathieu P. et al. | Secretase-independent and RhoGTPase/PAK/ERK-dependent regulation of cytoskeleton dynamics in astrocytes by NSAIDs and derivatives | Journal of Alzheimer's disease : JAD | 2010 | ISSN 1875--8908 |
| Chastre, Eric et al. | TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasiveness | The FASEB Journal | 2009 | ISSN 1530--6860 |
| Baumer, Y. et al. | Role of Rac 1 and cAMP in endothelial barrier stabilization and thrombin-induced barrier breakdown | Journal of Cellular Physiology | 2009 | ISSN 1097--4652 |
| Abu-Elneel, Kawther et al. | No Title | 2008 | PMID 18809680 | |
| Mercer, Jason et al. | Vaccinia virus uses macropinocytosis and apoptotic mimicry to enter host cells | Science (New York, N.Y.) | 2008 | ISSN 1095--9203 |
| Pontow, Suzanne et al. | Antiviral Activity of a Rac GEF inhibitor Characterized with a Sensitive HIV/SIV Fusion Assay | Virology | 2007 | ISSN 0042-6822 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Hiatt, Susan M. et al. | De novo mutations in the GTP/GDP-binding region of RALA, a RAS-like small GTPase, cause intellectual disability and developmental delay | PLoS Genetics | 2018 | ISSN 1553-7404 |
| Gu, Chunming et al. | RalA, a GTPase targeted by miR‑181a, promotes transformation and progression by activating the Ras‑related signaling pathway in chronic myelogenous leukemia | Oncotarget | 2016 | ISSN 1949--2553 |
| Papini, Diana et al. | TD-60 links RalA GTPase function to the CPC in mitosis | Nature Communications 2015 6:1 | 2015 | ISSN 2041--1723 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Nataraj, Nishanth Belugali et al. | Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors | Cell Reports | 2022 | ISSN 2211--1247 |
| Nataraj, Nishanth Belugali et al. | Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors | Cell Reports | 2022 | ISSN 2211-1247 |
| Swaminathan, Bhairavi et al. | Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration | Scientific Reports | 2022 | ISSN 2045-2322 |
| Mao, De Yu et al. | CLIC1 and CLIC4 mediate endothelial S1P receptor signaling to facilitate Rac1 and RhoA activity and function | Science Signaling | 2021 | ISSN 1937-9145 |
| Hofmann, Marco H. et al. | Bi-3406, a potent and selective sos1–kras interaction inhibitor, is effective in kras-driven cancers through combined mek inhibition | Cancer Discovery | 2021 | ISSN 2159-8290 |
| Tisi, Renata et al. | The Multi-Level Mechanism of Action of a Pan-Ras Inhibitor Explains its Antiproliferative Activity on Cetux****-Resistant Cancer Cells | Frontiers in Molecular Biosciences | 2021 | ISSN 2296-889X |
| Wang, Xuesong et al. | Sevof****** inhibits growth factor-induced angiogenesis through suppressing Rac1/paxillin/FAK and Ras/Akt/mTOR | Future oncology (London, England) | 2020 | ISSN 1744--8301 |
| Kim, Jin Hee et al. | Rational design of small molecule RHOA inhibitors for gastric cancer | The Pharmacogenomics Journal 2020 20:4 | 2020 | ISSN 1473--1150 |
| Lu, Hengyu et al. | Research paper resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR | Oncotarget | 2020 | ISSN 1949-2553 |
| Morgan, Chase J. et al. | Endogenous IQGAP1 and IQGAP3 do not functionally interact with Ras | Scientific Reports | 2019 | ISSN 2045-2322 |
| Zhao, Tuo et al. | Simulated Microgravity Reduces Focal Adhesions and Alters Cytoskeleton and Nuclear Positioning Leading to Enhanced Apoptosis via Suppressing FAK/RhoA-Mediated mTORC1/NF-κB and ERK1/2 Pathways | International Journal of Molecular Sciences | 2018 | ISSN 1422-0067 |
| Casique-Aguirre, Diana et al. | KRas4B-PDE6δ complex stabilization by small molecules obtained by virtual screening affects Ras signaling in pancreatic cancer 06 Biological Sciences 0601 Biochemistry and Cell Biology | BMC Cancer | 2018 | ISSN 1471-2407 |
| Wong, Gabrielle S. et al. | Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition letter | Nature Medicine | 2018 | ISSN 1546-170X |
| Li, Qing fen et al. | Activation of Ras in the Vascular Endothelium Induces Brain Vascular Malformations and Hemorrhagic Stroke | Cell Reports | 2018 | ISSN 2211-1247 |
| Huang, Jia Lin et al. | Lipoprotein-biomimetic nanostructure enables efficient targeting delivery of siRNA to Ras-activated glioblastoma cells via macropinocytosis | Nature Communications | 2017 | ISSN 2041-1723 |
| Chen, Guo Ping et al. | Inhibition of farnesyl pyrophosphate synthase attenuates high glucose-induced vascular smooth muscle cells proliferation | Molecular Medicine Reports | 2017 | ISSN 1791-3004 |
| Zhao, Chen Ze et al. | Inhibition of farnesyl pyrophosphate synthase improves pressure overload induced chronic cardiac remodeling | Scientific Reports | 2016 | ISSN 2045-2322 |
| Chen, Bin et al. | Alteration of mevalonate pathway related enzyme expressions in pressure overload-induced cardiac hypertrophy and associated heart failure with preserved ejection fraction | Cellular Physiology and Biochemistry | 2013 | ISSN 1421-9778 |
| Camargo, Livia De Lucca et al. | Endo-PDI is required for TNFα-induced angiogenesis | Free Radical Biology and Medicine | 2013 | ISSN 0891--5849 |
| Lee, Sei Jung et al. | Regulation of Hypoxia-inducible Factor 1α (HIF-1α) by Lysophosphatidic Acid Is Dependent on Interplay between p53 and Krüppel-like Factor 5 | The Journal of Biological Chemistry | 2013 | ISSN 0021-9258 |
| Gil-Henn, H. et al. | Arg/Abl2 promotes invasion and attenuates proliferation of breast cancer in vivo | Oncogene | 2013 | ISSN 0950-9232 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Nataraj, Nishanth Belugali et al. | Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors | Cell Reports | 2022 | ISSN 2211--1247 |
| Hassin, Ori et al. | Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients | Nature Communications 2022 13:1 | 2022 | ISSN 2041--1723 |
| Nataraj, Nishanth Belugali et al. | Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors | Cell Reports | 2022 | ISSN 2211-1247 |
| Walter, Lisa Marie et al. | Profilin2 regulates actin rod assembly in neuronal cells | Scientific Reports | 2021 | ISSN 2045-2322 |
| Rogg, Manuel et al. | SRGAP1 controls small rho GTPases to regulate podocyte foot process maintenance | Journal of the American Society of Nephrology | 2021 | ISSN 1533-3450 |
| Ghosh, Soma et al. | PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR | Cell Reports | 2021 | ISSN 2211-1247 |
| Rodríguez-Fdez, Sonia et al. | Lysine Acetylation Reshapes the Downstream Signaling Landscape of Vav1 in Lymphocytes | Cells | 2020 | ISSN 2073-4409 |
| Hung, Pei Shan et al. | The inhibition of Wnt restrain KRASG12V-driven metastasis in non-small-cell lung cancer | Cancers | 2020 | ISSN 2072-6694 |
| Lorenzo-Martín, L. Francisco et al. | VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma | Nature Communications | 2020 | ISSN 2041-1723 |
| Lee, Mi Nam et al. | The primary cilium directs osteopontin-induced migration of mesenchymal stem cells by regulating CD44 signaling and Cdc42 activation | Stem Cell Research | 2020 | ISSN 1876-7753 |
| Lorenzo-Martín, L. Francisco et al. | Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor | Oncogene | 2020 | ISSN 1476-5594 |
| Atala, Anthony | Re: MicroRNA-141 Suppresses Prostate Cancer Stem Cells and Metastasis by Targeting a Cohort of Pro-Metastasis Genes | The Journal of urology | 2017 | ISSN 1527-3792 |
| Cerikan, Berati et al. | Cell-Intrinsic Adaptation Arising from Chronic Ablation of a Key Rho GTPase Regulator | Developmental Cell | 2016 | ISSN 1878-1551 |
| Sarowar, Tasnuva et al. | Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2 | Molecular Brain | 2016 | ISSN 1756-6606 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Lee, Sang Joon et al. | AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence | Nature | 2021 | ISSN 1476-4687 |
| Simonetti, Manuela et al. | The impact of Semaphorin 4C/Plexin-B2 signaling on fear memory via remodeling of neuronal and synaptic morphology | Molecular Psychiatry | 2021 | ISSN 1476-5578 |
| dos Santos, Marlus Alves et al. | Human B cells infected by Trypanosoma cruzi undergo F-actin disruption and cell death via caspase-7 activation and cleavage of phospholipase Cγ1 | Immunobiology | 2020 | ISSN 1878--3279 |
| Talamás-Lara, Daniel et al. | Entamoeba histolytica and Entamoeba dispar: Morphological and Behavioral Differences Induced by Fibronectin through GTPases Activation and Actin-Binding Proteins | The Journal of eukaryotic microbiology | 2020 | ISSN 1550--7408 |
| Algaber, Anwar et al. | MicroRNA-340-5p inhibits colon cancer cell migration via targeting of RhoA | Scientific Reports 2020 10:1 | 2020 | ISSN 2045--2322 |
| Mei, Jie et al. | A DAAM1 3′-UTR SNP mutation regulates breast cancer metastasis through affecting miR-208a-5p-DAAM1-RhoA axis | Cancer Cell International | 2019 | ISSN 1475-2867 |
| Wu, Xuping et al. | Wnt5a induces ROR1 and ROR2 to activate RhoA in esophageal squamous cell carcinoma cells | Cancer Management and Research | 2019 | ISSN 1179-1322 |
| Elshaer, Sally L. et al. | Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinal vascular permeability in mice via inhibition of inflammation and the RhoA kinase pathway | Diabetologia | 2019 | ISSN 1432-0428 |
| Yan, Ting et al. | Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells | Journal of Biological Chemistry | 2018 | ISSN 1083-351X |
| Alizadeh, Javad et al. | Detection of small gtpase prenylation and gtp binding using membrane fractionation and gtpase-linked immunosorbent assay | Journal of Visualized Experiments | 2018 | ISSN 1940-087X |
| Kim, Jongshin et al. | YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation | Journal of Clinical Investigation | 2017 | ISSN 1558-8238 |
| Ruggiero, Carmen et al. | Dosage-dependent regulation of VAV2 expression by steroidogenic factor-1 drives adrenocortical carcinoma cell invasion | Science Signaling | 2017 | ISSN 1937-9145 |
| Paldy, Eszter et al. | Semaphorin 4C Plexin-B2 signaling in peripheral sensory neurons is pronociceptive in a model of inflammatory pain | Nature Communications | 2017 | ISSN 2041-1723 |
| López-Contreras, Luilli et al. | Structural and functional characterization of the divergent Entamoeba Src using Src inhibitor-1 | Parasites and Vectors | 2017 | ISSN 1756-3305 |
| Itano, Seiji et al. | Colchicine attenuates renal fibrosis in a murine unilateral ureteral obstruction model | Molecular Medicine Reports | 2017 | ISSN 1791-3004 |
| Nour-Eldine, Wared et al. | Adiponectin attenuates angiotensin II-induced vascular smooth muscle cell remodeling through nitric oxide and the RhoA/ROCK pathway | Frontiers in Pharmacology | 2016 | ISSN 1663-9812 |
| Park, Yong Hwan et al. | Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS | Nature Immunology | 2016 | ISSN 1529-2916 |
| Herrera-Martínez, Mayra et al. | Antiamoebic activity of Adenophyllum aurantium (L.) strother and its effect on the actin cytoskeleton of Entamoeba histolytica | Frontiers in Pharmacology | 2016 | ISSN 1663-9812 |
| Yan, Yi et al. | Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5 | Nature Communications | 2015 | ISSN 2041-1723 |
| Ajima, Rieko et al. | DAAM1 and DAAM2 are co-required for myocardial maturation and sarcomere assembly | Developmental Biology | 2015 | ISSN 1095-564X |
| Nakajima, Chikako et al. | The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development | Development (Cambridge) | 2014 | ISSN 1477-9129 |
| Lasgorceix, M. et al. | In vitro and in vivo evaluation of silicated hydroxyapatite and impact of insulin adsorption | Journal of Materials Science: Materials in Medicine | 2014 | ISSN 1573-4838 |
| Naraoka, Masato et al. | Suppression of the Rho/Rho-Kinase Pathway and Prevention of Cerebral Vasospasm by Combination Treatment with Statin and Fasudil After Subarachnoid Hemorrhage in Rabbit | Translational Stroke Research | 2013 | ISSN 1868-4483 |
| Herrera-Martínez, M. et al. | Actin, RhoA, and Rab11 participation during encystment in entamoeba invadens | BioMed Research International | 2013 | ISSN 2314-6133 |
| Bai, Xue et al. | The smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertension | Nature Communications | 2013 | ISSN 2041-1723 |
| Veeramah, Krishna R. et al. | Exome sequencing reveals new causal mutations in children with epileptic encephalopathies | Epilepsia | 2013 | ISSN 0013-9580 |
| Moniz, Sónia et al. | Loss of WNK2 expression by promoter gene methylation occurs in adult gliomas and triggers Rac1-mediated tumour cell invasiveness | Human molecular genetics | 2013 | ISSN 1460--2083 |
| Bray, Kristi et al. | Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration | Breast Cancer Research | 2013 | ISSN 1465-5411 |
| Nobe, Koji et al. | Two distinct dysfunctions in diabetic mouse mesenteric artery contraction are caused by changes in the Rho A-Rho kinase signaling pathway | European journal of pharmacology | 2012 | ISSN 1879--0712 |
| Wang, Jiping et al. | RhoA/ROCK-dependent moesin phosphorylation regulates AGE-induced endothelial cellular response | Cardiovascular Diabetology | 2012 | ISSN 1475-2840 |
| Zuo, Yufeng et al. | Cdc42 negatively regulates intrinsic migration of highly aggressive breast cancer cells | Journal of cellular physiology | 2012 | ISSN 1097--4652 |
| Doherty, Jason T. et al. | Skeletal muscle differentiation and fusion are regulated by the BAR-containing Rho-GTPase-activating Protein (Rho-GAP), GRAF | Journal of Biological Chemistry | 2011 | ISSN 0021-9258 |
| Alvarez, S. M. et al. | Failure of Bay K 8644 to induce RhoA kinase-dependent calcium sensitization in rabbit blood vessels | British journal of pharmacology | 2010 | ISSN 1476--5381 |
| Heckman-Stoddard, Brandy M. et al. | Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression | 2009 | ISSN 1465-5411 | |
| Chastre, Eric et al. | TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasiveness | The FASEB Journal | 2009 | ISSN 1530--6860 |
| Hammar, Eva et al. | Role of the Rho-ROCK (Rho-Associated Kinase) Signaling Pathway in the Regulation of Pancreatic β-Cell Function | Endocrinology | 2009 | ISSN 0013--7227 |
| Iesato, Ken et al. | Tiotropium bromide attenuates respiratory syncytial virus replication in epithelial cells | Respiration; international review of thoracic diseases | 2008 | ISSN 1423--0356 |
| Kinoshita, Nagatoki et al. | Apical Accumulation of Rho in the Neural Plate Is Important for Neural Plate Cell Shape Change and Neural Tube Formation | Molecular Biology of the Cell | 2008 | ISSN 1059-1524 |
| Moniz, Sónia et al. | WNK2 modulates MEK1 activity through the Rho GTPase pathway | Cellular signalling | 2008 | ISSN 0898--6568 |
| Schreibelt, Gerty et al. | Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 2007 | ISSN 1530--6860 |
| Scott, Glynis A. et al. | Lysophosphatidylcholine mediates melanocyte dendricity through PKCzeta activation | The Journal of investigative dermatology | 2007 | ISSN 1523--1747 |
| Tanaka, Shigeru et al. | Neural expression of G protein-coupled receptors GPR3, GPR6, and GPR12 up-regulates cyclic AMP levels and promotes neurite outgrowth | The Journal of biological chemistry | 2007 | ISSN 0021--9258 |
| Higashibata, Akira et al. | Influence of simulated microgravity on the activation of the small GTPase Rho involved in cytoskeletal formation - Molecular cloning and sequencing of bovine leukemia-associated guanine nucleotide exchange factor | BMC Biochemistry | 2006 | ISSN 1471-2091 |
| Woods, Anita et al. | RhoA/ROCK Signaling Regulates Chondrogenesis in a Context-dependent Manner * | Journal of Biological Chemistry | 2006 | ISSN 0021--9258 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Anastasaki, Corina et al. | Generation of human induced pluripotent stem cell-derived cerebral organoids for cellular and molecular characterization | STAR Protocols | 2022 | ISSN 2666--1667 |
| Vadakumchery, Anila et al. | The Small GTPase RHOA Links SLP65 Activation to PTEN Function in Pre B Cells and Is Essential for the Generation and Survival of Normal and Malignant B Cells | Frontiers in Immunology | 2022 | ISSN 1664-3224 |
| Zanin, Juan P. et al. | p75NTR prevents the onset of cerebellar granule cell migration via RhoA activation | eLife | 2022 | ISSN 2050-084X |
| Nath, Anu S. et al. | Modulation of the cell membrane lipid milieu by peroxisomal β-oxidation induces Rho1 signaling to trigger inflammatory responses | Cell Reports | 2022 | ISSN 2211-1247 |
| Kumar, Akhilesh et al. | Essential role of Rnd1 in innate immunity during viral and bacterial infections | Cell Death & Disease | 2022 | Article Link |
| Francis, Caitlin R. et al. | Rab35 governs apicobasal polarity through regulation of actin dynamics during sprouting angiogenesis | Nature Communications 2022 13:1 | 2022 | ISSN 2041--1723 |
| Xue, Tan et al. | Effects of Aster B-mediated intracellular accumulation of cholesterol on inflammatory process and myocardial cells in acute myocardial infarction | Hellenic Journal of Cardiology | 2022 | |
| Hauke, Michael et al. | Active RhoA Exerts an Inhibitory Effect on the Homeostasis and Angiogenic Capacity of Human Endothelial Cells | Journal of the American Heart Association | 2022 | ISSN 2047-9980 |
| Darp, Revati et al. | Oncogenic BRAF induces whole-genome doubling through suppression of cytokinesis | Nature Communications 2022 13:1 | 2022 | ISSN 2041--1723 |
| Meng, Zhipeng et al. | The Hippo pathway mediates Semaphorin signaling | Science Advances | 2022 | ISSN 2375-2548 |
| de Vallière, Cheryl et al. | pH-Sensing G Protein-Coupled Receptor OGR1 (GPR68) Expression and Activation Increases in Intestinal Inflammation and Fibrosis | International Journal of Molecular Sciences | 2022 | ISSN 1422-0067 |
| Wang, Kankai et al. | PTBP1 knockdown promotes neural differentiation of glioblastoma cells through UNC5B receptor | Theranostics | 2022 | ISSN 1838-7640 |
| Kumar, Akhilesh et al. | Essential role of Rnd1 in innate immunity during viral and bacterial infections | Cell Death & Disease 2022 13:6 | 2022 | ISSN 2041--4889 |
| Yadav, Vikas et al. | Increased MARCKS Activity in BRAF Inhibitor-Resistant Melanoma Cells Is Essential for Their Enhanced Metastatic Behavior Independent of Elevated WNT5A and IL-6 Signaling | Cancers | 2022 | ISSN 2072-6694 |
| Weder, Bruce et al. | New Therapeutic Approach for Intestinal Fibrosis Through Inhibition of pH-Sensing Receptor GPR4 | Inflammatory Bowel Diseases | 2022 | ISSN 1078--0998 |
| Sánchez-de la Torre, Aníbal et al. | Cannabinoid CB1 receptor gene inactivation in oligodendrocyte precursors disrupts oligodendrogenesis and myelination in mice | Cell Death & Disease 2022 13:7 | 2022 | ISSN 2041--4889 |
| Ma, Yuanyuan et al. | Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during tooth root development | Development (Cambridge) | 2021 | ISSN 1477-9129 |
| Zhou, Qun et al. | Inflammatory Immune Cytokine TNF-α Modulates Ezrin Protein Activation via FAK/RhoA Signaling Pathway in PMVECs Hyperpermeability | Frontiers in Pharmacology | 2021 | ISSN 1663-9812 |
| Jozic, Ivan et al. | Glucocorticoid-mediated induction of caveolin-1 disrupts cytoskeletal organization, inhibits cell migration and re-epithelialization of non-healing wounds | Communications Biology | 2021 | ISSN 2399-3642 |
| Gurusamy, Malarvizhi et al. | G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators | Nature Communications | 2021 | ISSN 2041-1723 |
| Shoda, Tetsuo et al. | Desmoplakin and periplakin genetically and functionally contribute to eosinophilic esophagitis | Nature Communications | 2021 | ISSN 2041-1723 |
| Krueger, Irena et al. | Reelin amplifies glycoprotein VI activation and alphaiib beta3 integrin outside-in signaling via PLC Gamma 2 and Rho GTPases | Arteriosclerosis, Thrombosis, and Vascular Biology | 2020 | ISSN 1524-4636 |
| Salgado-Lucio, Monica L. et al. | FAK regulates actin polymerization during sperm capacitation via the ERK2/GEF-H1/RhoA signaling pathway | Journal of Cell Science | 2020 | ISSN 1477-9137 |
| Lachowski, Dariusz et al. | G Protein-Coupled Estrogen Receptor Regulates Actin Cytoskeleton Dynamics to Impair Cell Polarization | Frontiers in Cell and Developmental Biology | 2020 | ISSN 2296-634X |
| Rong, Zhouyi et al. | Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aβ42 in triggering receptor expressed on myeloid cells 2 loss-of-function murine models | FASEB Journal | 2020 | ISSN 1530-6860 |
| Fox, Megan E. et al. | Dendritic remodeling of D1 neurons by RhoA/Rho-kinase mediates depression-like behavior | Molecular Psychiatry | 2020 | ISSN 1476-5578 |
| Hasan, Wan Nuraini Wan et al. | Annatto-derived tocotrienol promotes mineralization of MC3T3-E1 cells by enhancing BMP-2 protein expression via inhibiting RhoA activation and HMG-CoA reductase gene expression | Drug Design, Development and Therapy | 2020 | ISSN 1177-8881 |
| Bhosle, Vikrant K. et al. | SLIT2/ROBO1-signaling inhibits macropinocytosis by opposing cortical cytoskeletal remodeling | Nature Communications | 2020 | ISSN 2041-1723 |
| Porter, Lauren et al. | SUN1/2 Are Essential for RhoA/ROCK-Regulated Actomyosin Activity in Isolated Vascular Smooth Muscle Cells | Cells | 2020 | ISSN 2073-4409 |
| Dias Gomes, Martim et al. | Polarity signaling ensures epidermal homeostasis by coupling cellular mechanics and genomic integrity | Nature Communications | 2019 | ISSN 2041-1723 |
| Majolée, Jisca et al. | CSN5 inhibition triggers inflammatory signaling and Rho/ROCK-dependent loss of endothelial integrity | Scientific Reports | 2019 | ISSN 2045-2322 |
| Santhana Kumar, Karthiga et al. | TGF-β Determines the Pro-migratory Potential of bFGF Signaling in Medulloblastoma | Cell Reports | 2018 | ISSN 2211-1247 |
| Li, Xu et al. | A positive feedback loop of profilin-1 and RhoA/ROCK1 promotes endothelial dysfunction and oxidative stress | Oxidative Medicine and Cellular Longevity | 2018 | ISSN 1942-0994 |
| Schillaci, Odessa et al. | Exosomes from metastatic cancer cells transfer amoeboid phenotype to non-metastatic cells and increase endothelial permeability: Their emerging role in tumor heterogeneity | Scientific Reports | 2017 | ISSN 2045-2322 |
| Rom, Slava et al. | PARP inhibition in leukocytes diminishes inflammation via effects on integrins/cytoskeleton and protects the blood-brain barrier | Journal of Neuroinflammation | 2016 | ISSN 1742-2094 |
| Jackson, William D. et al. | Very-low and low-density lipoproteins induce neutral lipid accumulation and impair migration in monocyte subsets | Scientific Reports | 2016 | ISSN 2045-2322 |
| López-Posadas, Rocío et al. | Rho-A prenylation and signaling link epithelial homeostasis to intestinal inflammation | Journal of Clinical Investigation | 2016 | ISSN 1558-8238 |
| Yu, Yonghao et al. | Hydrogen-rich medium ameliorates lipopolysaccharide-induced barrier dysfunction via rhoa-mdia1 signaling in caco-2 cells | Shock | 2016 | ISSN 1540-0514 |
| Patra, Vijay Kumar et al. | The Skin Microbiome: Is It Affected by UV-induced Immune Suppression? | Frontiers in Microbiology | 2016 | ISSN 1664-302X |
| Lu, Wen Juan et al. | Senescence Mediated by p16INK4a Impedes Reprogramming of Human Corneal Endothelial Cells into Neural Crest Progenitors | Scientific Reports | 2016 | ISSN 2045-2322 |
| Rom, Slava et al. | The dual action of poly(ADP-ribose) polymerase -1 (PARP-1) inhibition in HIV-1 infection: HIV-1 ltr inhibition and diminution in Rho GTPase activity | Frontiers in Microbiology | 2015 | ISSN 1664-302X |
| Ochoa-Alvarez, Jhon A. et al. | Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanisms | Oncotarget | 2015 | ISSN 1949-2553 |
| Aifuwa, Ivie et al. | Senescent stromal cells induce cancer cell migration via inhibition of RhoA/ROCK/myosin-based cell contractility | Oncotarget | 2015 | ISSN 1949-2553 |
| Freeman, Spencer A. et al. | Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor | Nature Communications | 2015 | ISSN 2041-1723 |
| Tang, Xiao et al. | HCLOCK Causes Rho-Kinase-Mediated Endothelial Dysfunction and NF-κ B-Mediated Inflammatory Responses | Oxidative Medicine and Cellular Longevity | 2015 | ISSN 1942-0994 |
| Skrbic, Biljana et al. | Lack of collagen VIII reduces fibrosis and promotes early mortality and cardiac dilatation in pressure overload in mice | Cardiovascular Research | 2015 | ISSN 1755-3245 |
| Manukyan, Arkadi et al. | A complex of p190RhoGAP-A and anillin modulates RhoA-GTP and the cytokinetic furrow in human cells | Journal of Cell Science | 2015 | ISSN 1477-9137 |
| Rom, Slava et al. | Poly(ADP-ribose) polymerase-1 inhibition in brain endothelium protects the blood-brain barrier under physiologic and neuroinflammatory conditions | Journal of Cerebral Blood Flow and Metabolism | 2015 | ISSN 1559-7016 |
| Biechler V., Stefanie V. et al. | The impact of flow-induced forces on the morphogenesis of the outflow tract | Frontiers in Physiology | 2014 | ISSN 1664-042X |
| Mackay, Joanna L. et al. | Simultaneous and independent tuning of RhoA and Rac1 activity with orthogonally inducible promoters | Integrative Biology (United Kingdom) | 2014 | ISSN 1757-9708 |
| Chen, Xiaofei et al. | The TMEFF2 tumor suppressor modulates integrin expression, RhoA activation and migration of prostate cancer cells | Biochimica et Biophysica Acta - Molecular Cell Research | 2014 | ISSN 1879-2596 |
| Herr, Michael J. et al. | Tetraspanin CD9 regulates cell contraction and actin arrangement via RhoA in human vascular smooth muscle cells | PLoS ONE | 2014 | ISSN 1932-6203 |
| Zhu, Ying Ting et al. | Knockdown of both p120 catenin and kaiso promotes expansion of human corneal endothelial monolayers via rhoa-rock-noncanonical BMP-NFκB pathway | Investigative Ophthalmology and Visual Science | 2014 | ISSN 1552-5783 |
| Dubash, Adi D. et al. | The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1 | Journal of Cell Biology | 2013 | ISSN 0021-9525 |
| DiScipio, Richard G. et al. | Complement C3a signaling mediates production of angiogenic factors in mesenchymal stem cells | Journal of Biomedical Science and Engineering | 2013 | ISSN 1937--6871 |
| Rom, Slava et al. | Selective activation of cannabinoid receptor 2 in leukocytes suppresses their engagement of the brain endothelium and protects the blood-brain barrier | American Journal of Pathology | 2013 | ISSN 0002-9440 |
| Yang, Jian et al. | Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced cardiac hypertrophy and fibrosis in vivo | International Journal of Biochemistry and Cell Biology | 2013 | ISSN 1357-2725 |
| Papke, Christina L. et al. | Smooth muscle hyperplasia due to loss of smooth muscle α-actin is driven by activation of focal adhesion kinase, altered p53 localization and increased levels of platelet-derived growth factor receptor-β | Human Molecular Genetics | 2013 | ISSN 0964-6906 |
| Tan, Hong et al. | Fluid flow forces and rhoA regulate fibrous development of the atrioventricular valves | Developmental Biology | 2013 | ISSN 1095-564X |
| Kalia, Manjula et al. | Japanese Encephalitis Virus Infects Neuronal Cells through a Clathrin-Independent Endocytic Mechanism | Journal of Virology | 2013 | ISSN 0022--538X |
| Kanazawa, Yasushi et al. | The Rho-kinase inhibitor fasudil restores normal motor nerve conduction velocity in diabetic rats by assuring the proper localization of adhesion-related molecules in myelinating Schwann cells | Experimental neurology | 2013 | ISSN 1090--2430 |
| Zhou, Zhigang et al. | HSV-mediated gene transfer of C3 transferase inhibits Rho to promote axonal regeneration | Experimental Neurology | 2012 | ISSN 0014--4886 |
| Ramsay, Alan G. et al. | Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenali******: Establishing a reversible immune evasion mechanism in human cancer | Blood | 2012 | ISSN 1528-0020 |
| Chen, Si Meng et al. | Inhibition of tumor cell growth, proliferation and migration by X-387, a novel active-site inhibitor of mTOR | Biochemical Pharmacology | 2012 | ISSN 0006-2952 |
| Takefuji, Mikito et al. | G13-mediated signaling pathway is required for pressure overload-induced cardiac remodeling and heart failure | Circulation | 2012 | ISSN 0009-7322 |
| Howe, Grant A. et al. | RhoB controls endothelial cell morphogenesis in part via negative regulation of RhoA | Vascular Cell | 2012 | ISSN 2045--824X |
| Zhu, Ying Ting et al. | Nuclear p120 catenin unlocks mitotic block of contactinhibited human corneal endothelial monolayers without disrupting adherent junctions | Journal of Cell Science | 2012 | ISSN 0021-9533 |
| Yang, Seungwon et al. | The RhoA-ROCK-PTEN pathway as a molecular switch for anchorage dependent cell behavior | Biomaterials | 2012 | ISSN 1878--5905 |
| McCoy, Kelly L. et al. | Protease-activated receptor 1 (PAR1) coupling to G(q/11) but not to G(i/o) or G(12/13) is mediated by discrete amino acids within the receptor second intracellular loop | Cellular signalling | 2012 | ISSN 1873--3913 |
| Ramseyer, Vanesa D. et al. | Tumor necrosis factor α decreases nitric oxide synthase type 3 expression primarily via Rho/Rho kinase in the thick ascending limb | Hypertension (Dallas, Tex. : 1979) | 2012 | ISSN 1524--4563 |
| Dhaliwal, Anandika et al. | Cellular Cytoskeleton Dynamics Modulates Non-Viral Gene Delivery through RhoGTPases | 2012 | PMID 22509380 | |
| Greco, Carolina M. et al. | Chemotactic effect of prorenin on human aortic smooth muscle cells: a novel function of the (pro)renin receptor | Cardiovascular Research | 2012 | ISSN 0008--6363 |
| Chen, Guang et al. | Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells (Journal of Biological Chemistry (2012) 2 | Journal of Biological Chemistry | 2012 | ISSN 0021-9258 |
| Elali, Ayman et al. | Liver X receptor activation enhances blood-brain barrier integrity in the ischemic brain and increases the abundance of ATP-binding cassette transporters ABCB1 and ABCC1 on brain capillary cells | Brain Pathology | 2012 | ISSN 1015-6305 |
| Garrido‐Gómez, Tamara et al. | Annexin A2 is critical for embryo adhesiveness to the human endometrium by RhoA activation through F‐actin regulation | The FASEB Journal | 2012 | ISSN 0892--6638 |
| Ganguly, Riya et al. | Adiponectin Increases LPL Activity via RhoA/ROCK-Mediated Actin Remodelling in Adult Rat Cardiomyocytes | Endocrinology | 2011 | ISSN 0013--7227 |
| Mammoto, Tadanori et al. | Mechanochemical Control of Mesenchymal Condensation and Embryonic Tooth Organ Formation | Developmental Cell | 2011 | ISSN 1534-5807 |
| Aguilar, Hector N. et al. | Phos-tag-based analysis of myosin regulatory light chain phosphorylation in human uterine myocytes | PLoS ONE | 2011 | ISSN 1932-6203 |
| Jin, Wanzhu et al. | Increased SRF transcriptional activity in human and mouse skeletal muscle is a signature of insulin resistance | Journal of Clinical Investigation | 2011 | ISSN 0021-9738 |
| Musso, Alessandra et al. | Relevance of the mevalonate biosynthetic pathway in the regulation of bone marrow mesenchymal stromal cell-mediated effects on T-cell proliferation and B-cell survival | Haematologica | 2011 | ISSN 1592--8721 |
| Ridgway, Lon D. et al. | Modulation of GEF-H1 Induced Signaling by Heparanase in Brain Metastatic Melanoma Cells | Journal of cellular biochemistry | 2010 | ISSN 0730-2312 |
| Rapier, Rebecca et al. | The extracellular matrix microtopography drives critical changes in cellular motility and Rho A activity in colon cancer cells | Cancer Cell International | 2010 | ISSN 1475-2867 |
| Lichtenstein, Mathieu P. et al. | Secretase-independent and RhoGTPase/PAK/ERK-dependent regulation of cytoskeleton dynamics in astrocytes by NSAIDs and derivatives | Journal of Alzheimer's disease : JAD | 2010 | ISSN 1875--8908 |
| Yang, Enyue et al. | Fluoride induces vascular contraction through activation of RhoA/Rho kinase pathway in isolated rat aortas | Environmental toxicology and pharmacology | 2010 | ISSN 1872--7077 |
| Nini, Lylia et al. | Accurate and reproducible measurements of RhoA activation in small samples of primary cells | Analytical biochemistry | 2010 | ISSN 1096--0309 |
| Romero, Ana M. et al. | Chronic ethanol exposure alters the levels, assembly, and cellular organization of the actin cytoskeleton and microtubules in hippocampal neurons in primary culture | Toxicological Sciences | 2010 | ISSN 1096-6080 |
| Chastre, Eric et al. | TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasiveness | The FASEB Journal | 2009 | ISSN 1530--6860 |
| Hammar, Eva et al. | Role of the Rho-ROCK (Rho-Associated Kinase) Signaling Pathway in the Regulation of Pancreatic β-Cell Function | Endocrinology | 2009 | ISSN 0013--7227 |
| Seifert, Jennifer L. et al. | Differential activation of Rac1 and RhoA in neuroblastoma cell fractions | Neuroscience letters | 2009 | ISSN 0304--3940 |
| Mercer, Jason et al. | Vaccinia virus uses macropinocytosis and apoptotic mimicry to enter host cells | Science (New York, N.Y.) | 2008 | ISSN 1095--9203 |
| Kinoshita, Nagatoki et al. | Apical Accumulation of Rho in the Neural Plate Is Important for Neural Plate Cell Shape Change and Neural Tube Formation | Molecular Biology of the Cell | 2008 | ISSN 1059-1524 |
| Korobova, Farida et al. | Arp2/3 complex is important for filopodia formation, growth cone motility, and neuritogenesis in neuronal cells | Molecular biology of the cell | 2008 | ISSN 1939--4586 |
| Ramirez, Servio H. et al. | Activation of Peroxisome Proliferator-Activated Receptor γ (PPARγ) Suppresses Rho GTPases in Human Brain Microvascular Endothelial Cells and Inhibits Adhesion and Transendothelial Migration of HIV-1 Infected Monocytes | The Journal of Immunology | 2008 | ISSN 0022--1767 |
| Moore, Simon W. et al. | Rho inhibition recruits DCC to the neuronal plasma membrane and enhances axon chemoattraction to netrin 1 | Development | 2008 | ISSN 0950--1991 |
| Sequeira, Linda et al. | Rho GTPases in PC-3 prostate cancer cell morphology, invasion and tumor cell diapedesis | Clinical & experimental metastasis | 2008 | ISSN 0262--0898 |
| Schreibelt, Gerty et al. | Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 2007 | ISSN 1530--6860 |
| Rupp, Paul A. et al. | A role for RhoA in the two-phase migratory pattern of post-otic neural crest cells | Developmental Biology | 2007 | ISSN 0012-1606 |
| Keely, Patricia J. et al. | Investigating integrin regulation and signaling events in three-dimensional systems | Methods in enzymology | 2007 | ISSN 0076--6879 |
| Tanaka, Shigeru et al. | Neural expression of G protein-coupled receptors GPR3, GPR6, and GPR12 up-regulates cyclic AMP levels and promotes neurite outgrowth | The Journal of biological chemistry | 2007 | ISSN 0021--9258 |
| Bradley, William D. et al. | Integrin Signaling through Arg Activates p190RhoGAP by Promoting Its Binding to p120RasGAP and Recruitment to the Membrane | Molecular Biology of the Cell | 2006 | ISSN 1059-1524 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Lee, Sang Joon et al. | AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence | Nature | 2021 | ISSN 1476-4687 |
| Porter, Lauren et al. | SUN1/2 Are Essential for RhoA/ROCK-Regulated Actomyosin Activity in Isolated Vascular Smooth Muscle Cells | Cells | 2020 | ISSN 2073-4409 |
| Ngai, David et al. | DDR1 (Discoidin Domain Receptor-1)-RhoA (Ras Homolog Family Member A) Axis Senses Matrix Stiffness to Promote Vascular Calcification | Arteriosclerosis, Thrombosis, and Vascular Biology | 2020 | ISSN 1524-4636 |
| Lachowski, Dariusz et al. | G Protein-Coupled Estrogen Receptor Regulates Actin Cytoskeleton Dynamics to Impair Cell Polarization | Frontiers in Cell and Developmental Biology | 2020 | ISSN 2296-634X |
| Chronopoulos, Antonios et al. | Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway | Nature Materials | 2020 | ISSN 1476-4660 |
| Haq, Naila et al. | Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neurons | PLoS Biology | 2019 | ISSN 1545-7885 |
| Dér, Bálint et al. | NK2 receptor-mediated detrusor muscle contraction involves Gq/11-dependent activation of voltage-dependent Ca2+ channels and the RhoA-Rho kinase pathway | American Journal of Physiology - Renal Physiology | 2019 | ISSN 1522-1466 |
| Zhang, Xiaoqing et al. | Alterations of MEK1/2-ERK1/2, IFNγ and Smad2/3 associated Signalling pathways during cryopreservation of ASCs affect their differentiation towards VSMC-like cells | Stem Cell Research | 2018 | ISSN 1876-7753 |
| Giannini, Marianna et al. | Nano-topography: Quicksand for cell cycle progression? | Nanomedicine: Nanotechnology, Biology, and Medicine | 2018 | ISSN 1549-9642 |
| Peng, Jing Hua et al. | Geniposide and Chlorogenic Acid Combination Ameliorates Non-alcoholic Steatohepatitis Involving the Protection on the Gut Barrier Function in Mouse Induced by High-Fat Diet | Frontiers in Pharmacology | 2018 | ISSN 1663-9812 |
| Tod, Jo et al. | Pro-migratory and TGF-β-activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switch | Journal of Pathology | 2017 | ISSN 1096-9896 |
| Schillaci, Odessa et al. | Exosomes from metastatic cancer cells transfer amoeboid phenotype to non-metastatic cells and increase endothelial permeability: Their emerging role in tumor heterogeneity | Scientific Reports | 2017 | ISSN 2045-2322 |
| Kempf, Anissa et al. | Control of Cell Shape, Neurite Outgrowth, and Migration by a Nogo-A/HSPG Interaction | Developmental Cell | 2017 | ISSN 1878-1551 |
| Dyberg, Cecilia et al. | Rho-associated kinase is a therapeutic target in neuroblastoma | Proceedings of the National Academy of Sciences of the United States of America | 2017 | ISSN 1091-6490 |
| Park, Yong Hwan et al. | Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS | Nature Immunology | 2016 | ISSN 1529-2916 |
| Al-Shboul, Othman | The role of the RhoA/ROCK pathway in gender-dependent differences in gastric smooth muscle contraction | Journal of Physiological Sciences | 2016 | ISSN 1880-6546 |
| Jiang, Lisheng et al. | Selective activation of CB2 receptor improves efferocytosis in cultured macrophages | Life Sciences | 2016 | ISSN 1879-0631 |
| Yuan, Xue et al. | Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation | Nature Communications | 2016 | ISSN 2041-1723 |
| Escuin, Sarah et al. | Rho-kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closure | Journal of Cell Science | 2015 | ISSN 1477-9137 |
| Skrbic, Biljana et al. | Lack of collagen VIII reduces fibrosis and promotes early mortality and cardiac dilatation in pressure overload in mice | Cardiovascular Research | 2015 | ISSN 1755-3245 |
| Suen, J. Y. et al. | Pathway-selective antagonism of proteinase activated receptor 2 | British Journal of Pharmacology | 2014 | ISSN 1476-5381 |
| Herr, Michael J. et al. | Tetraspanin CD9 regulates cell contraction and actin arrangement via RhoA in human vascular smooth muscle cells | PLoS ONE | 2014 | ISSN 1932-6203 |
| Biechler V., Stefanie V. et al. | The impact of flow-induced forces on the morphogenesis of the outflow tract | Frontiers in Physiology | 2014 | ISSN 1664-042X |
| Tan, Hong et al. | Fluid flow forces and rhoA regulate fibrous development of the atrioventricular valves | Developmental Biology | 2013 | ISSN 1095-564X |
| Valtcheva, Nadejda et al. | The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42 | Journal of Biological Chemistry | 2013 | ISSN 0021-9258 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Flores-Muñoz, Carolina et al. | The Long-Term Pannexin 1 Ablation Produces Structural and Functional Modifications in Hippocampal Neurons | Cells | 2022 | ISSN 2073-4409 |
| Moreiras, Hugo et al. | Melanocore uptake by keratinocytes occurs through phagocytosis and involves protease-activated receptor-2 internalization | Traffic | 2022 | ISSN 1600--0854 |
| Liu, Yao et al. | Exosomes derived from stem cells from apical papilla promote craniofacial soft tissue regeneration by enhancing Cdc42-mediated vascularization | Stem Cell Research and Therapy | 2021 | ISSN 1757-6512 |
| Bian, Rui et al. | Research paper rac gtpase activating protein 1 promotes gallbladder cancer via binding DNA ligase 3 to reduce apoptosis | International Journal of Biological Sciences | 2021 | ISSN 1449-2288 |
| Qi, Yan et al. | Rhoa/rock pathway activation is regulated by at1 receptor and participates in smooth muscle migration and dedifferentiation via promoting actin cytoskeleton polymerization | International Journal of Molecular Sciences | 2020 | ISSN 1422-0067 |
| Frye, Maike et al. | Ephrinb2-ephb4 signalling provides rho-mediated homeostatic control of lymphatic endothelial cell junction integrity | eLife | 2020 | ISSN 2050-084X |
| Brisson, Lucie et al. | P2X7 receptor promotes mouse mammary cancer cell invasiveness and tumour progression, and is a target for anticancer treatment | Cancers | 2020 | ISSN 2072-6694 |
| Dupraz, Sebastian et al. | RhoA Controls Axon Extension Independent of Specification in the Developing Brain | Current Biology | 2019 | ISSN 0960-9822 |
| Birkl, Dorothee et al. | TNFα promotes mucosal wound repair through enhanced platelet activating factor receptor signaling in the epithelium | Mucosal Immunology | 2019 | ISSN 1935-3456 |
| Tang, Lian et al. | RhoA/ROCK signaling regulates smooth muscle phenotypic modulation and vascular remodeling via the JNK pathway and vimentin cytoskeleton | Pharmacological Research | 2018 | ISSN 1096-1186 |
| Cheng, Lili et al. | Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity | Archives of Toxicology | 2018 | ISSN 1432-0738 |
| Tiwari, Richa et al. | Depletion of keratin 8/18 modulates oncogenic potential by governing multiple signaling pathways | FEBS Journal | 2018 | ISSN 1742-4658 |
| Pan, Yu et al. | Dissection of glomerular transcriptional profile in patients with diabetic nephropathy: SRGAP2a protects podocyte structure and function | Diabetes | 2018 | ISSN 1939-327X |
| Li, Yan et al. | Aerobic exercise regulates Rho/cofilin pathways to rescue synaptic loss in aged rats | PLoS ONE | 2017 | ISSN 1932-6203 |
| Majumder, Piyali et al. | Cellular levels of Grb2 and cytoskeleton stability are correlated in a neurodegenerative scenario | DMM Disease Models and Mechanisms | 2017 | ISSN 1754-8411 |
| Bon, Emeline et al. | SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancer | Nature Communications | 2016 | ISSN 2041-1723 |
| Zhang, Liang et al. | A lateral signalling pathway coordinates shape volatility during cell migration | Nature Communications | 2016 | ISSN 2041-1723 |
| Liu, Chunqiao et al. | A secreted WNT-ligand-binding domain of FZD5 generated by a frameshift mutation causes autosomal dominant coloboma | Human Molecular Genetics | 2016 | ISSN 1460-2083 |
| Medapati, Manoj Reddy et al. | RAGE mediates the pro-migratory response of extracellular S100A4 in human thyroid cancer cells | Thyroid | 2015 | ISSN 1557-9077 |
| Tang, Jianjun et al. | Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer | Oncotarget | 2014 | ISSN 1949-2553 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Nawrotek, Agata et al. | PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling | Nature Chemical Biology | 2019 | ISSN 1552-4469 |
| Abdul-Salam, Vahitha B. et al. | CLIC4/Arf6 Pathway: A New Lead in BMPRII Inhibition in Pulmonary Hypertension | Circulation Research | 2019 | ISSN 1524-4571 |
| Romani, Patrizia et al. | Extracellular matrix mechanical cues regulate lipid metabolism through Lipin-1 and SREBP | Nature Cell Biology | 2019 | ISSN 1476-4679 |
| Yu, Qingfeng et al. | A NAV2729-sensitive mechanism promotes adrenergic smooth muscle contraction and growth of stromal cells in the human prostate | Journal of Biological Chemistry | 2019 | ISSN 1083-351X |
| Sasai, Miwa et al. | Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense | Nature Immunology | 2017 | ISSN 1529-2916 |
| Ríos, Amelia et al. | Participation of Rho, ROCK-2, and GAP activities during actin microfilament rearrangements in Entamoeba histolytica induced by fibronectin signaling | Cell Biology International | 2008 | ISSN 1065-6995 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Wang, Yilin et al. | Cytohesin-2/ARNO: A Novel Bridge Between Cell Migration and Immunoregulation in Synovial Fibroblasts | Frontiers in Immunology | 2022 | |
| Oga, Takafumi et al. | Genomic profiles of colorectal carcinoma with liver metastases and newly identified fusion genes | Cancer science | 2019 | ISSN 1349--7006 |
| Abdul-Salam, Vahitha B. et al. | CLIC4/Arf6 Pathway: A New Lead in BMPRII Inhibition in Pulmonary Hypertension | Circulation Research | 2019 | ISSN 1524-4571 |
| Yu, Qingfeng et al. | A NAV2729-sensitive mechanism promotes adrenergic smooth muscle contraction and growth of stromal cells in the human prostate | Journal of Biological Chemistry | 2019 | ISSN 1083-351X |
| Früh, Simon et al. | The catalytic function of the gephyrin-binding protein IQSEC3 regulates neurotransmitter-specific matching of pre- and post-synaptic structures in primary hippocampal cultures | Journal of Neurochemistry | 2018 | ISSN 1471-4159 |
| Krey, Jocelyn F. et al. | ELMOD1 stimulates ARF6-GTP hydrolysis to stabilize apical structures in developing vestibular hair cells | Journal of Neuroscience | 2018 | ISSN 1529-2401 |
| Herlemann, Annika et al. | Inhibition of smooth muscle contraction and ARF6 activity by the inhibitor for cytohesin GEFs, secinH3, in the human prostate | American Journal of Physiology - Renal Physiology | 2018 | ISSN 1522-1466 |
| Chen, Yu Ju et al. | RAS SF4 controls SOCE and ER-PM junctions through regulation of PI(4,5)P2 | Journal of Cell Biology | 2017 | ISSN 1540-8140 |
| Berg-Larsen, Axel et al. | Differential Regulation of Rab GTPase Expression in Monocyte-Derived Dendritic Cells upon Lipopolysaccharide Activation: A Correlation to Maturation-Dependent Functional Properties | PLoS ONE | 2013 | ISSN 1932-6203 |
| Ríos, Amelia et al. | Participation of Rho, ROCK-2, and GAP activities during actin microfilament rearrangements in Entamoeba histolytica induced by fibronectin signaling | Cell Biology International | 2008 | ISSN 1065-6995 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Spel, Lotte et al. | CDC42 regulates PYRIN inflammasome assembly | Cell Reports | 2022 | ISSN 2211--1247 |
| Khan, Alamzeb et al. | ArhGEF12 activates Rap1A and not RhoA in human dermal microvascular endothelial cells to reduce tumor necrosis factor-induced leak | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 2022 | ISSN 1530-6860 |
| Li, Xiaopeng et al. | Hhex inhibits cell migration via regulating RHOA/CDC42-CFL1 axis in human lung cancer cells | Cell Communication and Signaling | 2021 | ISSN 1478-811X |
| McCray, Brett A. et al. | Neuropathy-causing TRPV4 mutations disrupt TRPV4-RhoA interactions and impair neurite extension | Nature Communications | 2021 | ISSN 2041-1723 |
| Zhou, Yongjie et al. | Congenital biliary atresia is correlated with disrupted cell junctions and polarity caused by Cdc42 insufficiency in the liver | Theranostics | 2021 | ISSN 1838-7640 |
| Li, Chunsen et al. | GEFT Inhibits Autophagy and Apoptosis in Rhabdomyosarcoma via Activation of the Rac1/Cdc42-mTOR Signaling Pathway | Frontiers in Oncology | 2021 | ISSN 2234-943X |
| Hosseini, Kamran et al. | EMT-Induced Cell-Mechanical Changes Enhance Mitotic Rounding Strength | Advanced Science | 2020 | ISSN 2198-3844 |
| Zhang, Jiawei et al. | In vivo and in vitro activation of dormant primordial follicles by EGF treatment in mouse and human | Clinical and Translational Medicine | 2020 | ISSN 2001--1326 |
| Lian, Eric Y. et al. | RET isoforms contribute differentially to invasive processes in pancreatic ductal adenocarcinoma | Oncogene | 2020 | ISSN 1476-5594 |
| Chen, Lixia et al. | CSRP2 suppresses colorectal cancer progression via p130Cas/Rac1 axis-meditated ERK, PAK, and HIPPO signaling pathways | Theranostics | 2020 | ISSN 1838-7640 |
| Gu, Jiawen et al. | Rho-GEF trio regulates osteoclast differentiation and function by Rac1/Cdc42 | Experimental Cell Research | 2020 | ISSN 1090-2422 |
| Lang, Yue et al. | MiR-30 family prevents uPAR-ITGB3 signaling activation through calcineurin-NFATC pathway to protect podocytes | Cell Death and Disease | 2019 | ISSN 2041-4889 |
| Liu, Chunxia et al. | Epigenetically upregulated GEFT-derived invasion and metastasis of rhabdomyosarcoma via epithelial mesenchymal transition promoted by the Rac1/Cdc42-PAK signalling pathway | EBioMedicine | 2019 | ISSN 2352-3964 |
| Zhou, Yi Fan et al. | Sema3E/PlexinD1 signaling inhibits postischemic angiogenesis by regulating endothelial DLL4 and filopodia formation in a rat model of ischemic stroke | FASEB Journal | 2019 | ISSN 1530-6860 |
| Dagliyan, Onur et al. | Engineering proteins for allosteric control by light or ligands | Nature Protocols | 2019 | ISSN 1750-2799 |
| Carvalho, J. R. et al. | Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration | eLife | 2019 | ISSN 2050-084X |
| Veluthakal, Rajakrishnan et al. | Restoration of glucose-stimulated Cdc42-PAK1 activation and insulin secretion by a selective Epac activator in type 2 diabetic human islets | Diabetes | 2018 | ISSN 1939-327X |
| Sepúlveda-Ramírez, Silvia P. et al. | Cdc42 controls primary mesenchyme cell morphogenesis in the sea urchin embryo | Developmental Biology | 2018 | ISSN 1095-564X |
| Chavali, Manideep et al. | Non-canonical Wnt signaling regulates neural stem cell quiescence during homeostasis and after demyelination | Nature Communications | 2018 | ISSN 2041-1723 |
| Yang, Huan et al. | Cytotoxic Necrotizing Factor 1 Downregulates CD36 Transcription in Macrophages to Induce Inflammation During Acute Urinary Tract Infections | Frontiers in Immunology | 2018 | ISSN 1664-3224 |
| Saito, Masaki et al. | Tctex‐1 controls ciliary resorption by regulating branched actin polymerization and endocytosis | EMBO reports | 2017 | ISSN 1469--221X |
| Tormos, Ana M. et al. | P38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging | PLoS ONE | 2017 | ISSN 1932-6203 |
| Guo, Yaxiu et al. | Cytotoxic necrotizing factor 1 promotes prostate cancer progression through activating the Cdc42–PAK1 axis | Journal of Pathology | 2017 | ISSN 1096-9896 |
| Sunkavalli, Ushasree et al. | Analysis of host microRNA function uncovers a role for miR-29b-2-5p in Shigella capture by filopodia | PLoS Pathogens | 2017 | ISSN 1553-7374 |
| Vidal-Quadras, Maite et al. | Endocytic turnover of Rab8 controls cell polarization | Journal of Cell Science | 2017 | ISSN 1477-9137 |
| Yao, Zhihui et al. | P311 Accelerates Skin Wound Reepithelialization by Promoting Epidermal Stem Cell Migration Through RhoA and Rac1 Activation | Stem Cells and Development | 2017 | ISSN 1557-8534 |
| Zhan, Rixing et al. | Nitric oxide promotes epidermal stem cell migration via cGMP-Rho GTPase signalling | Scientific Reports | 2016 | ISSN 2045-2322 |
| Jia, L. et al. | KLF5 promotes breast cancer proliferation, migration and invasion in part by upregulating the transcription of TNFAIP2 | Oncogene | 2016 | ISSN 1476-5594 |
| Moodley, Serisha et al. | Stimulus-dependent dissociation between XB130 and Tks5 scaffold proteins promotes airway epithelial cell migration | Oncotarget | 2016 | ISSN 1949-2553 |
| Zhan, Rixing et al. | Nitric oxide enhances keratinocyte cell migration by regulating Rho GTPase via cGMP-PKG signalling | PLoS ONE | 2015 | ISSN 1932-6203 |
| Tang, Xiaoyun et al. | Lipid phosphate phosphatase-1 expression in cancer cells attenuates tumor growth and metastasis in mice | Journal of Lipid Research | 2014 | ISSN 1539-7262 |
| Ricotti, Leonardo et al. | Boron nitride nanotube-mediated stimulation modulates F/G-actin ratio and mechanical properties of human dermal fibroblasts | Journal of Nanoparticle Research | 2014 | ISSN 1388-0764 |
| Knowles, Byron C. et al. | Myosin Vb uncoupling from RAB8A and RAB11A elicits microvillus inclusion disease | Journal of Clinical Investigation | 2014 | ISSN 1558-8238 |
| Nithipatikom, Kasem et al. | Cannabinoid receptor type 1 (CB1) activation inhibits small GTPase RhoA activity and regulates motility of prostate carcinoma cells | Endocrinology | 2012 | ISSN 1945--7170 |
| Sakabe, Isamu et al. | Age-related guanine nucleotide exchange factor, mouse Zizimin2, induces filopodia in bone marrow-derived dendritic cells | Immunity and Ageing | 2012 | ISSN 1742-4933 |
| Nikolic, Damjan S. et al. | HIV-1 activates Cdc42 and induces membrane extensions in immature dendritic cells to facilitate cell-to-cell virus propagation | Blood | 2011 | ISSN 1528-0020 |
| Asai, Akira et al. | Involvement of Rac GTPase activation in phosphatidylcholine hydroperoxide-induced THP-1 cell adhesion to ICAM-1 | Biochemical and biophysical research communications | 2011 | ISSN 1090--2104 |
| Abu-Elneel, Kawther et al. | No Title | 2008 | PMID 18809680 | |
| Broman, Michael T. et al. | Cdc42 regulates adherens junction stability and endothelial permeability by inducing α-catenin interaction with the vascular endothelial cadherin complex | Circulation Research | 2006 | ISSN 0009-7330 |
| Slice, Lee W. et al. | Angiotensin II and epidermal growth factor induce cyclooxygenase-2 expression in intestinal epithelial cells through small GTPases using distinct signaling pathways | The Journal of biological chemistry | 2005 | ISSN 0021--9258 |
| Nur-E-Kamal, Alam et al. | Three dimensional nanofibrillar surfaces induce activation of Rac | Biochemical and biophysical research communications | 2005 | ISSN 0006--291X |
| Chellaiah, Meenakshi A. | Regulation of actin ring formation by Rho GTPases in osteoclasts | Journal of Biological Chemistry | 2005 | ISSN 0021-9258 |
| Tang, Dale D. et al. | The adapter protein CrkII regulates neuronal Wiskott-Aldrich syndrome protein, actin polymerization, and tension development during contractile stimulation of smooth muscle | Journal of Biological Chemistry | 2005 | ISSN 0021-9258 |
| Tang, Dale D. et al. | The small GTPase Cdc42 regulates actin polymerization and tension development during contractile stimulation of smooth muscle | Journal of Biological Chemistry | 2004 | ISSN 0021-9258 |
| Sasai, Noriaki et al. | The neurotrophin-receptor-related protein NRH1 is essential for convergent extension movements | 2004 | PMID 15258592 | |
| Liu, Xiu-Fen et al. | Nucleotide Exchange Factor ECT2 Interacts with the Polarity Protein Complex Par6/Par3/Protein Kinase Cζ (PKCζ) and Regulates PKCζ Activity | Molecular and Cellular Biology | 2004 | ISSN 0270--7306 |
| Vogl, Thomas et al. | MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes | Blood | 2004 | ISSN 0006-4971 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Ding, Jiuyang et al. | Low and high dose methamphetamine differentially regulate synaptic structural plasticity in cortex and hippocampus | Frontiers in Cellular Neuroscience | 2022 | ISSN 1662-5102 |
| Posor, York et al. | Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover | Developmental Cell | 2022 | ISSN 1534--5807 |
| Lei, Bo et al. | Social experiences switch states of memory engrams through regulating hippocampal Rac1 activity | Proceedings of the National Academy of Sciences of the United States of America | 2022 | ISSN 1091-6490 |
| Xu, Weiyi et al. | Paxillin promotes breast tumor collective cell invasion through maintenance of adherens junction integrity | Molecular biology of the cell | 2022 | ISSN 1939-4586 |
| Xu, Weiyi et al. | Paxillin promotes breast tumor collective cell invasion through maintenance of adherens junction integrity | Molecular Biology of the Cell | 2022 | ISSN 1939-4586 |
| Jiang, Lizhu et al. | Time of Day-Dependent Alteration of Hippocampal Rac1 Activation Regulates Contextual Fear Memory in Rats | Frontiers in Molecular Neuroscience | 2022 | ISSN 1662-5099 |
| Alalem, Mohamed et al. | Mutant p53 Depletion by Novel Inhibitors for HSP40/J-Domain Proteins Derived from the Natural Compound Plumbagin | Cancers | 2022 | ISSN 2072-6694 |
| Afanasyeva, Elena A. et al. | Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma | Life Science Alliance | 2021 | ISSN 2575-1077 |
| Lo, Louisa Hoi Ying et al. | The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation | Cell Reports | 2020 | ISSN 2211-1247 |
| Ramírez-Ramírez, Danelia et al. | Rac1 is necessary for capacitation and acrosome reaction in guinea pig spermatozoa | Journal of cellular biochemistry | 2020 | ISSN 1097--4644 |
| Wu, Wenjuan et al. | Inhibition of Rac1-dependent forgetting alleviates memory deficits in animal models of Alzheimer’s disease | Protein and Cell | 2019 | ISSN 1674-8018 |
| Lv, Li et al. | Interplay between α2-chimaerin and Rac1 activity determines dynamic maintenance of long-term memory | Nature Communications | 2019 | ISSN 2041-1723 |
| Huang, Yuxing et al. | Arp2/3-branched actin maintains an active pool of GTP-RhoA and controls RhoA abundance | Cells | 2019 | ISSN 2073-4409 |
| Liu, Yunlong et al. | Social Isolation Induces Rac1-Dependent Forgetting of Social Memory | Cell Reports | 2018 | ISSN 2211-1247 |
| Wang, Jinyang et al. | Rho A Regulates Epidermal Growth Factor-Induced Human Osteosarcoma MG63 Cell Migration | International journal of molecular sciences | 2018 | ISSN 1422--0067 |
| Morrison Joly, Meghan et al. | Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis | Breast Cancer Research | 2017 | ISSN 1465-542X |
| Li, Shufeng et al. | Microtopographical features generated by photopolymerization recruit RhoA/ROCK through TRPV1 to direct cell and neurite growth | Biomaterials | 2015 | ISSN 1878-5905 |
| Allison, Patrick et al. | Type III TGFβ receptor and Src direct hyaluronan-mediated invasive cell motility | Cellular Signalling | 2015 | ISSN 1873-3913 |
| Mattias, Leino et al. | The effects of artificial E-cadherin matrix-induced embryonic stem cell scattering on paxillin and RhoA activation via α-catenin | Biomaterials | 2014 | ISSN 1878-5905 |
| Sabbatini, Maria Eugenia et al. | Cholecystokinin-Mediated RhoGDI Phosphorylation via PKCα Promotes both RhoA and Rac1 Signaling | PLoS ONE | 2013 | ISSN 1932-6203 |
| Castillo-Pichardo, Linette et al. | Dietary grape polyphenol resveratrol increases mammary tumor growth and metastasis in immunocompromised mice | 2013 | PMID 23298290 | |
| Gray, Jason D. et al. | LRP6 exerts non-canonical effects on Wnt signaling during neural tube closure | Human Molecular Genetics | 2013 | ISSN 0964-6906 |
| Zou, Wenying et al. | AKT-mediated regulation of polarization in differentiated human neutrophil-like HL-60 cells | Inflammation research : official journal of the European Histamine Research Society ... [et al.] | 2012 | ISSN 1420--908X |
| Ladhani, Omar et al. | Pigment Epithelium-Derived Factor Blocks Tumor Extravasation by Suppressing Amoeboid Morphology and Mesenchymal Proteolysis | Neoplasia (New York, N.Y.) | 2011 | ISSN 1476-5586 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Morretton, Jean-Philippe et al. | A catalog of numerical centrosome defects in epithelial ovarian cancers | EMBO Molecular Medicine | 2022 | ISSN 1757--4684 |
| Singh, Neeraj et al. | BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1 | Science Advances | 2022 | ISSN 2375-2548 |
| Wang, Yuting et al. | EPS8L1 promotes migration and metastasis of ovarian cancer by activating Rac1/MAPK signaling pathway via upregulating TIAM2 | Authorea Preprints | 2022 | Article Link |
| Adan, Hanad et al. | Activated Src requires Cadherin-11, Rac, and gp130 for Stat3 activation and survival of mouse Balb/c3T3 fibroblasts | Cancer Gene Therapy 2022 29:10 | 2022 | ISSN 1476--5500 |
| Usuki, Seigo et al. | Konjac Ceramide (kCer)-Mediated Signal Transduction of the Sema3A Pathway Promotes HaCaT Keratinocyte Differentiation | Biology | 2022 | ISSN 2079-7737 |
| Karthikeyan, Subbulakshmi et al. | RAB4A GTPase regulates epithelial-to-mesenchymal transition by modulating RAC1 activation | Breast Cancer Research | 2022 | ISSN 1465-542X |
| Adan, H et al. | Activated Src requires Cadherin-11, Rac, and gp130 for Stat3 activation and survival of mouse Balb/c3T3 fibroblasts | Cancer Gene … | 2022 | Article Link |
| Khan, Alamzeb et al. | ArhGEF12 activates Rap1A and not RhoA in human dermal microvascular endothelial cells to reduce tumor necrosis factor-induced leak | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 2022 | ISSN 1530-6860 |
| Masi, Ilenia et al. | Endothelin-1 drives invadopodia and interaction with mesothelial cells through ILK | Cell Reports | 2021 | ISSN 2211-1247 |
| Wang, Junyi et al. | Rho-GEF Trio regulates osteosarcoma progression and osteogenic differentiation through Rac1 and RhoA | Cell Death and Disease | 2021 | ISSN 2041-4889 |
| Guo, Shuyu et al. | Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development | Theranostics | 2021 | ISSN 1838-7640 |
| Wang, Jiang Lin et al. | Spinophilin modulates pain through suppressing dendritic spine morphogenesis via negative control of Rac1-ERK signaling in rat spinal dorsal horn | Neurobiology of Disease | 2021 | ISSN 1095-953X |
| Zhou, Wenqing et al. | Mitofusin 2 regulates neutrophil adhesive migration and the actin cytoskeleton | Journal of Cell Science | 2021 | ISSN 1477-9137 |
| Bai, Xiaoyuan et al. | Induction of cyclophilin A by influenza A virus infection facilitates group A Streptococcus coinfection | Cell Reports | 2021 | ISSN 2211-1247 |
| Li, Chunsen et al. | GEFT Inhibits Autophagy and Apoptosis in Rhabdomyosarcoma via Activation of the Rac1/Cdc42-mTOR Signaling Pathway | Frontiers in Oncology | 2021 | ISSN 2234-943X |
| Agbaegbu Iweka, Chinyere et al. | The lipid phosphatase-like protein PLPPR1 associates with RhoGDI1 to modulate RhoA activation in response to axon growth inhibitory molecules | Journal of Neurochemistry | 2021 | ISSN 1471-4159 |
| Floerchinger, Alessia et al. | Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging | Cell Reports | 2021 | ISSN 2211-1247 |
| McCray, Brett A. et al. | Neuropathy-causing TRPV4 mutations disrupt TRPV4-RhoA interactions and impair neurite extension | Nature Communications | 2021 | ISSN 2041-1723 |
| Romano, Roberta et al. | Alteration of the late endocytic pathway in Charcot–Marie–Tooth type 2B disease | Cellular and Molecular Life Sciences | 2021 | ISSN 1420-9071 |
| Barabutis, Nektarios et al. | Protective mechanism of the selective vasopressin V1A receptor agonist selepressin against endothelial barrier dysfunction | Journal of Pharmacology and Experimental Therapeutics | 2020 | ISSN 1521-0103 |
| Fulmer, Diana et al. | Desert hedgehog-primary cilia cross talk shapes mitral valve tissue by organizing smooth muscle actin | Developmental Biology | 2020 | ISSN 1095-564X |
| Wei, Yiju et al. | NEDD 4L‐mediated Merlin ubiquitination facilitates Hippo pathway activation | EMBO reports | 2020 | ISSN 1469--221X |
| Danelon, Victor et al. | Modular and Distinct Plexin-A4/FARP2/Rac1 Signaling Controls Dendrite Morphogenesis | Journal of Neuroscience | 2020 | ISSN 1529-2401 |
| Aladowicz, Ewa et al. | Shcd binds dock4, promotes ameboid motility and metastasis dissemination, predicting poor prognosis in melanoma | Cancers | 2020 | ISSN 2072-6694 |
| Won, So Yeon et al. | Fibulin 5, a human Wharton's jelly-derived mesenchymal stem cells-secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin-RAC1 signaling axis | Stem Cells | 2020 | ISSN 1549-4918 |
| Wang, Ruixiao et al. | Rac1 silencing, NSC23766 and EHT1864 reduce growth and actin organization of bladder smooth muscle cells | Life Sciences | 2020 | ISSN 1879-0631 |
| Moody, Jasmine C. et al. | The Rho-GEF PIX-1 directs assembly or stability of lateral attachment structures between muscle cells | Nature Communications | 2020 | ISSN 2041-1723 |
| Smalley, Tracess et al. | The Atypical Protein Kinase C Small Molecule Inhibitor ζ-Stat, and Its Effects on Invasion Through Decreases in PKC-ζ Protein Expression | Frontiers in Oncology | 2020 | ISSN 2234-943X |
| Shin, Seung Kak et al. | Exogenous 8-hydroxydeoxyguanosine ameliorates liver fibrosis through the inhibition of Rac1-NADPH oxidase signaling | Journal of gastroenterology and hepatology | 2020 | ISSN 1440--1746 |
| Benz, Peter M. et al. | AKAP12 deficiency impairs VEGF-induced endothelial cell migration and sprouting | Acta physiologica (Oxford, England) | 2020 | ISSN 1748--1716 |
| Li, Zean et al. | The metastatic promoter DEPDC1B induces epithelial‐mesenchymal transition and promotes prostate cancer cell proliferation via Rac1‐PAK1 signaling | Clinical and Translational Medicine | 2020 | ISSN 2001--1326 |
| Joshi, Rakesh et al. | DLC1 SAM domain-binding peptides inhibit cancer cell growth and migration by inactivating RhoA | Journal of Biological Chemistry | 2020 | ISSN 1083-351X |
| Chen, Lixia et al. | CSRP2 suppresses colorectal cancer progression via p130Cas/Rac1 axis-meditated ERK, PAK, and HIPPO signaling pathways | Theranostics | 2020 | ISSN 1838-7640 |
| Larribère, Lionel et al. | NF1-RAC1 axis regulates migration of the melanocytic lineage | Translational Oncology | 2020 | ISSN 1936-5233 |
| Lian, Eric Y. et al. | RET isoforms contribute differentially to invasive processes in pancreatic ductal adenocarcinoma | Oncogene | 2020 | ISSN 1476-5594 |
| Thamilselvan, Vijayalakshmi et al. | P-Rex1 Mediates Glucose-Stimulated Rac1 Activation and Insulin Secretion in Pancreatic β-Cells | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2020 | ISSN 1421--9778 |
| Ichikawa, Takehiko et al. | Non-junctional role of Cadherin3 in cell migration and contact inhibition of locomotion via domain-dependent, opposing regulation of Rac1 | Scientific Reports | 2020 | ISSN 2045-2322 |
| Yu, Qingfeng et al. | A NAV2729-sensitive mechanism promotes adrenergic smooth muscle contraction and growth of stromal cells in the human prostate | Journal of Biological Chemistry | 2019 | ISSN 1083-351X |
| Liu, Chunxia et al. | Epigenetically upregulated GEFT-derived invasion and metastasis of rhabdomyosarcoma via epithelial mesenchymal transition promoted by the Rac1/Cdc42-PAK signalling pathway | EBioMedicine | 2019 | ISSN 2352-3964 |
| Park, Jin Seok et al. | Switch-like enhancement of epithelial-mesenchymal transition by YAP through feedback regulation of WT1 and Rho-family GTPases | Nature Communications | 2019 | ISSN 2041-1723 |
| Tsygankova, Oxana M. et al. | A unique role for clathrin light chain A in cell spreading and migration | Journal of Cell Science | 2019 | ISSN 1477-9137 |
| Lang, Yue et al. | MiR-30 family prevents uPAR-ITGB3 signaling activation through calcineurin-NFATC pathway to protect podocytes | Cell Death and Disease | 2019 | ISSN 2041-4889 |
| Dagliyan, Onur et al. | Engineering proteins for allosteric control by light or ligands | Nature Protocols | 2019 | ISSN 1750-2799 |
| Zhou, Yi Fan et al. | Sema3E/PlexinD1 signaling inhibits postischemic angiogenesis by regulating endothelial DLL4 and filopodia formation in a rat model of ischemic stroke | FASEB Journal | 2019 | ISSN 1530-6860 |
| Wong, Bin Sheng et al. | A direct podocalyxin–dynamin-2 interaction regulates cytoskeletal dynamics to promote migration and metastasis in pancreatic cancer cells | Cancer Research | 2019 | ISSN 1538-7445 |
| Amato, Clelia et al. | WASP Restricts Active Rac to Maintain Cells’ Front-Rear Polarization | Current Biology | 2019 | ISSN 0960-9822 |
| Herlemann, Annika et al. | Inhibition of smooth muscle contraction and ARF6 activity by the inhibitor for cytohesin GEFs, secinH3, in the human prostate | American Journal of Physiology - Renal Physiology | 2018 | ISSN 1522-1466 |
| Wu, Yuqing et al. | Mycobacterial infection is promoted by neutral sphingomyelinase 2 regulating a signaling cascade leading to activation of β1-integrin | Cellular Physiology and Biochemistry | 2018 | ISSN 1421-9778 |
| Zago, Giulia et al. | Ralb directly triggers invasion downstream ras by mobilizing the wave complex | eLife | 2018 | ISSN 2050-084X |
| Barabutis, Nektarios et al. | Wild-type p53 enhances endothelial barrier function by mediating RAC1 signalling and RhoA inhibition | Journal of Cellular and Molecular Medicine | 2018 | ISSN 1582-1838 |
| Hayashi, Kentaro et al. | Intracellular calcium signal at the leading edge regulates mesodermal sheet migration during Xenopus gastrulation | Scientific Reports | 2018 | ISSN 2045-2322 |
| Shang, Wanjing et al. | Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation | Proceedings of the National Academy of Sciences of the United States of America | 2018 | ISSN 1091-6490 |
| Liu, Yunlong et al. | Social Isolation Induces Rac1-Dependent Forgetting of Social Memory | Cell Reports | 2018 | ISSN 2211-1247 |
| Hayes, Madeline N. et al. | Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma | Cell Stem Cell | 2018 | ISSN 1875-9777 |
| McQueeney, Kelley E. et al. | Targeting ovarian cancer and endothelium with an allosteric PTP4A3 phosphatase inhibitor | Oncotarget | 2018 | ISSN 1949-2553 |
| Shi, Hao et al. | Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R-STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity | Immunity | 2018 | ISSN 1097-4180 |
| Yang, Huan et al. | Cytotoxic Necrotizing Factor 1 Downregulates CD36 Transcription in Macrophages to Induce Inflammation During Acute Urinary Tract Infections | Frontiers in Immunology | 2018 | ISSN 1664-3224 |
| Tarr, Joseph T. et al. | The pivotal role of CCN2 in mammalian palatogenesis | Journal of Cell Communication and Signaling | 2017 | ISSN 1873-961X |
| Yao, Zhihui et al. | P311 Accelerates Skin Wound Reepithelialization by Promoting Epidermal Stem Cell Migration Through RhoA and Rac1 Activation | Stem Cells and Development | 2017 | ISSN 1557-8534 |
| Guo, Yaxiu et al. | Cytotoxic necrotizing factor 1 promotes prostate cancer progression through activating the Cdc42–PAK1 axis | Journal of Pathology | 2017 | ISSN 1096-9896 |
| Gao, Jie et al. | The E3 ubiquitin ligase IDOL regulates synaptic ApoER2 levels and is important for plasticity and learning | eLife | 2017 | ISSN 2050-084X |
| Margiotta, Azzurra et al. | Rab7a regulates cell migration through Rac1 and vimentin | Biochimica et Biophysica Acta - Molecular Cell Research | 2017 | ISSN 1879-2596 |
| Tormos, Ana M. et al. | P38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging | PLoS ONE | 2017 | ISSN 1932-6203 |
| Zhan, Rixing et al. | Nitric oxide promotes epidermal stem cell migration via cGMP-Rho GTPase signalling | Scientific Reports | 2016 | ISSN 2045-2322 |
| Han, Jie et al. | Farnesyl pyrophosphate synthase inhibitor, ibandronate, improves endothelial function in spontaneously hypertensive rats | Molecular Medicine Reports | 2016 | ISSN 1791-3004 |
| Tie, S. R. et al. | Regulation of sarcoma cell migration, invasion and invadopodia formation by AFAP1L1 through a phosphotyrosine-dependent pathway | Oncogene | 2016 | ISSN 1476-5594 |
| Wang, Yan et al. | Involvement of Rac1 signalling pathway in the development and maintenance of acute inflammatory pain induced by bee venom injection | British Journal of Pharmacology | 2016 | ISSN 1476-5381 |
| Wang, Y. et al. | Inhibition of prostate smooth muscle contraction and prostate stromal cell growth by the inhibitors of Rac, NSC23766 and EHT1864 | British Journal of Pharmacology | 2015 | ISSN 1476-5381 |
| Wang, Shi Jie et al. | CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells | Oncotarget | 2015 | ISSN 1949-2553 |
| Zhan, Rixing et al. | Nitric oxide enhances keratinocyte cell migration by regulating Rho GTPase via cGMP-PKG signalling | PLoS ONE | 2015 | ISSN 1932-6203 |
| Tang, Xiaoyun et al. | Lipid phosphate phosphatase-1 expression in cancer cells attenuates tumor growth and metastasis in mice | Journal of Lipid Research | 2014 | ISSN 1539-7262 |
| Hara, Yusuke et al. | Directional migration of leading-edge mesoderm generates physical forces: Implication in Xenopus notochord formation during gastrulation | Developmental Biology | 2013 | ISSN 1095-564X |
| Zallocchi, Marisa et al. | α1β1 Integrin/rac1-dependent mesangial invasion of glomerular capillaries in alport syndrome | American Journal of Pathology | 2013 | ISSN 0002-9440 |
| Geletu, M. et al. | Classical cadherins control survival through the gp130/Stat3 axis | Biochimica et Biophysica Acta - Molecular Cell Research | 2013 | ISSN 0167-4889 |
| Han, Gangwen et al. | Preventive and therapeutic effects of Smad7 on radiation-induced oral mucositis | Nature Medicine | 2013 | ISSN 1078-8956 |
| Lee, Wonhwa et al. | Barrier protective effects of withaferin A in HMGB1-induced inflammatory responses in both cellular and animal models | Toxicology and applied pharmacology | 2012 | ISSN 1096--0333 |
| Nithipatikom, Kasem et al. | Cannabinoid receptor type 1 (CB1) activation inhibits small GTPase RhoA activity and regulates motility of prostate carcinoma cells | Endocrinology | 2012 | ISSN 1945--7170 |
| Ninkovi, Jana et al. | Morphine decreases bacterial phagocytosis by inhibiting actin polymerization through cAMP-, Rac-1-, and p38 MAPK-dependent mechanisms | American Journal of Pathology | 2012 | ISSN 0002-9440 |
| Wong, Hon Kit et al. | Merlin/NF2 regulates angiogenesis in schwannomas through a Rac1/semaphorin 3F-dependent mechanism | Neoplasia | 2012 | ISSN 1476-5586 |
| Syed, Ismail et al. | L-threo-C 6 -pyridinium-ceramide bromide, a novel cationic ceramide, induces NADPH oxidase activation, mitochondrial dysfunction and loss in cell viability in INS 832/13 β-cells | Cellular Physiology and Biochemistry | 2012 | ISSN 1421-9778 |
| Gastonguay, Adam et al. | The role of Rac1 in the regulation of NF-kB activity, cell proliferation, and cell migration in non-small cell lung carcinoma | Cancer Biology & Therapy | 2012 | ISSN 1538--4047 |
| Jayaram, Bhavaani et al. | Isoprenylcysteine carboxyl methyltransferase facilitates glucose-induced Rac1 activation, ROS generation and insulin secretion in INS 832/13 β-cells | Islets | 2011 | ISSN 1938-2014 |
| Souma, Tomokazu et al. | Luminal alkalinization attenuates proteinuria-induced oxidative damage in proximal tubular cells | Journal of the American Society of Nephrology | 2011 | ISSN 1046-6673 |
| Vidal-Quadras, Maite et al. | Rac1 and Calmodulin Interactions Modulate Dynamics of ARF6-Dependent Endocytosis | Traffic | 2011 | ISSN 1398-9219 |
| Balanis, Nikolas et al. | β3 integrin-EGF receptor cross-talk activates p190RhoGAP in mouse mammary gland epithelial cells | Molecular Biology of the Cell | 2011 | ISSN 1059-1524 |
| Garkavtsev, Igor et al. | Dehydro-α-lapachone, a plant product with antivascular activity | Proceedings of the National Academy of Sciences of the United States of America | 2011 | ISSN 0027-8424 |
| McAuley, Erin M. et al. | Phenylboronic acid is a more potent inhibitor than boric acid of key signaling networks involved in cancer cell migration | Cell Adhesion and Migration | 2011 | ISSN 1933-6926 |
| Ock, Chan Young et al. | A novel approach for stress-induced gastritis based on paradoxical anti-oxidative and anti-inflammatory action of exogenous 8-hydroxydeoxyguanosine | Biochemical pharmacology | 2011 | ISSN 1873--2968 |
| Skalski, Michael et al. | SNARE-mediated membrane traffic is required for focal adhesion kinase signaling and Src-regulated focal adhesion turnover | Biochimica et Biophysica Acta - Molecular Cell Research | 2011 | ISSN 0167-4889 |
| Kobayashi, Takashi et al. | Activation of Rac1 is closely related to androgen-independent cell proliferation of prostate cancer cells both in vitro and in vivo | Molecular Endocrinology | 2010 | ISSN 0888-8809 |
| Medhora, Meetha et al. | 20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2008 | ISSN 1040-0605 |
| Bergstrom, R. A. et al. | Agrin induced morphological and structural changes in growth cones of cultured hippocampal neurons | Neuroscience | 2007 | ISSN 0306-4522 |
| Wang, Guoyan et al. | Genetic ablation of Rac1 in cartilage results in chondrodysplasia | Developmental Biology | 2007 | ISSN 0012-1606 |
| Slice, Lee W. et al. | Angiotensin II and epidermal growth factor induce cyclooxygenase-2 expression in intestinal epithelial cells through small GTPases using distinct signaling pathways | The Journal of biological chemistry | 2005 | ISSN 0021--9258 |
| Vogl, Thomas et al. | MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes | Blood | 2004 | ISSN 0006-4971 |
| Sasai, Noriaki et al. | The neurotrophin-receptor-related protein NRH1 is essential for convergent extension movements | 2004 | PMID 15258592 | |
| Yang, Seun Ah et al. | Rho and Rho-kinase mediate thrombin-induced phosphatidylinositol 4-phosphate 5-kinase trafficking in platelets | Journal of Biological Chemistry | 2004 | ISSN 0021-9258 |
| Zhang, Yongjun et al. | Distinct roles of two structurally closely related focal adhesion proteins, alpha-parvins and beta-parvins, in regulation of cell morphology and survival | The Journal of biological chemistry | 2004 | ISSN 0021--9258 |
| Chromy, Brett A. et al. | Self-assembly of Abeta(1-42) into globular neurotoxins | Biochemistry | 2003 | ISSN 0006--2960 |
| Quadri, Sadiqa K. et al. | Endothelial Barrier Strengthening by Activation of Focal Adhesion Kinase * | Journal of Biological Chemistry | 2003 | ISSN 0021--9258 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Long, Yufei et al. | FOXD1-dependent RalA-ANXA2-Src complex promotes CTC formation in breast cancer | Journal of Experimental and Clinical Cancer Research | 2022 | ISSN 1756-9966 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Cruz-Nova, Pedro et al. | 131I-C19 Iodide Radioisotope and Synthetic I-C19 Compounds as K-Ras4B–PDE6δ Inhibitors: A Novel Approach against Colorectal Cancer—Biological Characterization, Biokinetics and Dosimetry | Molecules 2022, Vol. 27, Page 5446 | 2022 | ISSN 1420--3049 |
| Jeon, S M et al. | Blockade of PD-L1/PD-1 signaling promotes osteo-/odontogenic differentiation through Ras activation | International Journal of … | 2022 | Article Link |
| Kirolos, Sara A. et al. | A chemorepellent inhibits local Ras activation to inhibit pseudopod formation to bias cell movement away from the chemorepellent | Molecular Biology of the Cell | 2022 | ISSN 1939-4586 |
| Carnevale, Julia et al. | RASA2 ablation in T cells boosts antigen sensitivity and long-term function | Nature 2022 609:7925 | 2022 | ISSN 1476--4687 |
| Jeon, So Mi et al. | Blockade of PD-L1/PD-1 signaling promotes osteo-/odontogenic differentiation through Ras activation | International Journal of Oral Science 2022 14:1 | 2022 | ISSN 2049--3169 |
| Song, Dan et al. | NSUN2-mediated mRNA m5C Modification Regulates the Progression of Hepatocellular Carcinoma | Genomics, Proteomics & Bioinformatics | 2022 | ISSN 1672--0229 |
| Bortolami, Alessandro et al. | Integrin-KCNB1 potassium channel complexes regulate neocortical neuronal development and are implicated in epilepsy | Cell Death & Differentiation 2022 | 2022 | ISSN 1476--5403 |
| Zhu, Dantong et al. | Loss of PTEN-Induced Kinase 1 Regulates Oncogenic Ras-Driven Tumor Growth By Inhibiting Mitochondrial Fission | Frontiers in Oncology | 2022 | ISSN 2234-943X |
| Kirolos, Sara A. et al. | A chemorepellent inhibits local Ras activation to inhibit pseudopod formation to bias cell movement away from the chemorepellent | Molecular biology of the cell | 2022 | ISSN 1939-4586 |
| Tulpule, Asmin et al. | Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules | Cell | 2021 | ISSN 1097-4172 |
| Ablain, Julien et al. | SPRED1 deletion confers resistance to MAPK inhibition in melanoma | The Journal of experimental medicine | 2021 | ISSN 1540-9538 |
| Wiley, Christopher D. et al. | Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis | Cell Metabolism | 2021 | ISSN 1932-7420 |
| Yan, Wupeng et al. | Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR | Cell Reports | 2020 | ISSN 2211-1247 |
| Cai, Diana et al. | Identification and characterization of oncogenic SOS1 mutations in lung adenocarcinoma | Molecular Cancer Research | 2019 | ISSN 1557-3125 |
| Cocco, Emiliano et al. | Resistance to TRK inhibition mediated by convergent MAPK pathway activation | Nature Medicine | 2019 | ISSN 1546-170X |
| Brandt, Raphael et al. | Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium | Nature Communications | 2019 | ISSN 2041-1723 |
| Hood, Fiona E. et al. | Isoform-specific Ras signaling is growth factor dependent | Molecular Biology of the Cell | 2019 | ISSN 1939-4586 |
| Rijal, Ramesh et al. | An endogenous chemorepellent directs cell movement by inhibiting pseudopods at one side of cells | Molecular Biology of the Cell | 2019 | ISSN 1939-4586 |
| Pilling, Darrell et al. | Different Isoforms of the Neuronal Guidance Molecule Slit2 Directly Cause Chemoattraction or Chemorepulsion of Human Neutrophils | The Journal of Immunology | 2019 | ISSN 0022--1767 |
| Saikia, Minakshi et al. | Heteronemin, a marine natural product, sensitizes acute myeloid leukemia cells towards cytarabine chemotherapy by regulating farnesylation of Ras | Oncotarget | 2018 | ISSN 1949-2553 |
| Dardaei, Leila et al. | SHP2 inhibition restores sensitivity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors | Nature Medicine | 2018 | ISSN 1546-170X |
| Smolkin, Tatyana et al. | Complexes of plexin-A4 and plexin-D1 convey semaphorin-3C signals to induce cytoskeletal collapse in the absence of neuropilins | Journal of Cell Science | 2018 | ISSN 1477-9137 |
| Lu, Xinyuan et al. | MET exon 14 mutation encodes an actionable therapeutic target in lung adenocarcinoma | Cancer Research | 2017 | ISSN 1538-7445 |
| Whiteside, Theresa L. | Therapeutic targeting of oncogenic KRAS in pancreatic cancer by engineered exosomes | Translational Cancer Research | 2017 | ISSN 2219-6803 |
| Malchers, Florian et al. | Mechanisms of primary drug resistance in FGFR1-amplified lung cancer | Clinical Cancer Research | 2017 | ISSN 1557-3265 |
| Walton, Josephine B. et al. | CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity | Scientific Reports | 2017 | ISSN 2045-2322 |
| Ilinskaya, Olga N. et al. | Direct inhibition of oncogenic KRAS by Bacillus pumilus ribonuclease (binase) | Biochimica et Biophysica Acta - Molecular Cell Research | 2016 | ISSN 1879-2596 |
| Hrustanovic, Gorjan et al. | RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer | Nature Medicine | 2015 | ISSN 1546-170X |
| Larribere, Lionel et al. | NF1 loss induces senescence during human melanocyte differentiation in an iPSC-based model | Pigment Cell and Melanoma Research | 2015 | ISSN 1755-148X |
| Yan, Chao et al. | Discovery and characterization of small molecules that target the GTPase Ral | 2014 | ISSN 1476--4687 | |
| Du, Chang Qing et al. | Inhibition of farnesyl pyrophosphate synthase prevents norepinephrine- induced fibrotic responses in vascular smooth muscle cells from spontaneously hypertensive rats | Hypertension Research | 2014 | ISSN 0916-9636 |
| Ciaglia, Elena et al. | N6-isopentenyladenosine, an endogenous isoprenoid end product, directly affects cytotoxic and regulatory functions of human NK cells through FDPS modulation | Journal of Leukocyte Biology | 2013 | ISSN 1938--3673 |
| Stoppa, Giovanna et al. | Ras signaling contributes to survival of human T-cell leukemia/lymphoma virus type 1 (HTLV-1) Tax-positive T-cells | Apoptosis : an international journal on programmed cell death | 2012 | ISSN 1573--675X |
| Kern, F. et al. | Essential, non-redundant roles of B-Raf and Raf-1 in Ras-driven skin tumorigenesis | Oncogene 2013 32:19 | 2012 | ISSN 1476--5594 |
| Kowluru, Renu A. | Role of Matrix Metalloproteinase-9 in the Development of Diabetic Retinopathy and Its Regulation by H-Ras | Investigative Ophthalmology & Visual Science | 2010 | ISSN 0146-0404 |
| Jiang, Xiao Sheng et al. | Activation of Rho GTPases in Smith-Lemli-Opitz syndrome: pathophysiological and clinical implications | Human molecular genetics | 2010 | ISSN 1460--2083 |
| Rose, A. et al. | Stimulatory effects of the multi-kinase inhibitor sorafenib on human bladder cancer cells | British Journal of Pharmacology | 2010 | ISSN 0007-1188 |
| Lito, Piro et al. | Evidence that sprouty 2 is necessary for sarcoma formation by H-Ras oncogene-transformed human fibroblasts | The Journal of biological chemistry | 2008 | ISSN 0021--9258 |
| Wasylyk, Christine et al. | Inhibition of the Ras-Net (Elk-3) pathway by a novel pyrazole that affects microtubules | Cancer Research | 2008 | ISSN 0008-5472 |
| Wang, J. X. et al. | Investigation of the immunosuppressive activity of artemether on T-cell activation and proliferation | British Journal of Pharmacology | 2007 | ISSN 0007-1188 |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Spel, Lotte et al. | CDC42 regulates PYRIN inflammasome assembly | Cell Reports | 2022 | ISSN 2211--1247 |
| Almarán, Beatriz et al. | Rnd3 Is a Crucial Mediator of the Invasive Phenotype of Glioblastoma Cells Downstream of Receptor Tyrosine Kinase Signalling | Cells | 2022 | ISSN 2073-4409 |
| Zheng, Cankun et al. | CX3CL1 Worsens Cardiorenal Dysfunction and Serves as a Therapeutic Target of Canagliflozin for Cardiorenal Syndrome | Frontiers in Pharmacology | 2022 | ISSN 1663-9812 |
| Soda, Tomohiro et al. | Loss of KAP3 decreases intercellular adhesion and impairs intracellular transport of laminin in signet ring cell carcinoma of the stomach | Scientific Reports | 2022 | ISSN 2045-2322 |
| Kholmanskikh, Stanislav et al. | Activation of RhoC by regulatory ubiquitination is mediated by LNX1 and suppressed by LIS1 | Scientific Reports 2022 12:1 | 2022 | ISSN 2045--2322 |
| Xu, Weiyi et al. | Paxillin promotes breast tumor collective cell invasion through maintenance of adherens junction integrity | Molecular Biology of the Cell | 2022 | ISSN 1939-4586 |
| Loria, Rossella et al. | SEMA6A/RhoA/YAP axis mediates tumor-stroma interactions and prevents response to dual BRAF/MEK inhibition in BRAF-mutant melanoma | Journal of Experimental and Clinical Cancer Research | 2022 | ISSN 1756-9966 |
| Soda, Tomohiro et al. | Loss of KAP3 decreases intercellular adhesion and impairs intracellular transport of laminin in signet ring cell carcinoma of the stomach | Scientific Reports 2022 12:1 | 2022 | ISSN 2045--2322 |
| Qian, Zhanyang et al. | Activation of glucagon-like peptide-1 receptor in microglia attenuates neuroinflammation-induced glial scarring via rescuing Arf and Rho GAP adapter protein 3 expressions after nerve injury | International Journal of Biological Sciences | 2022 | ISSN 1449-2288 |
| Shin, Yuna et al. | NPFFR2 Contributes to the Malignancy of Hepatocellular Carcinoma Development by Activating RhoA/YAP Signaling | Cancers | 2022 | ISSN 2072-6694 |
| Mahly, Adnan et al. | Anillin governs mitotic rounding during early epidermal development | BMC Biology | 2022 | ISSN 1741-7007 |
| Swiatlowska, Pamela et al. | Pressure and stiffness sensing together regulate vascular smooth muscle cell phenotype switching | Science Advances | 2022 | ISSN 2375-2548 |
| Yokoyama, Yusuke et al. | Crumbs3 is expressed in oral squamous cell carcinomas and promotes cell migration and proliferation by affecting RhoA activity | Oncology Letters | 2022 | ISSN 1792-1082 |
| Usuki, Seigo et al. | Konjac Ceramide (kCer)-Mediated Signal Transduction of the Sema3A Pathway Promotes HaCaT Keratinocyte Differentiation | Biology | 2022 | ISSN 2079-7737 |
| Vittoria, Marc A. et al. | Inactivation of the Hippo tumor suppressor pathway promotes melanoma | Nature Communications 2022 13:1 | 2022 | ISSN 2041--1723 |
| Rackow, Ashley R. et al. | The Novel Small Molecule BTB Inhibits Pro-Fibrotic Fibroblast Behavior though Inhibition of RhoA Activity | International Journal of Molecular Sciences | 2022 | ISSN 1422-0067 |
| Hamuro, Junji et al. | Repressed miR-34a Expression Dictates the Cell Fate to Corneal Endothelium Failure | Investigative Ophthalmology & Visual Science | 2022 | ISSN 1552--5783 |
| Seetharaman, Shailaja et al. | Microtubules tune mechanosensitive cell responses | Nature Materials | 2022 | ISSN 1476-4660 |
| Lee, Jiyoung et al. | Role of MCP-1 and IL-8 in viral anterior uveitis, and contractility and fibrogenic activity of trabecular meshwork cells | Scientific Reports | 2021 | ISSN 2045-2322 |
| Miao, Chunhui et al. | An infection-induced RhoB-Beclin 1-Hsp90 complex enhances clearance of uropathogenic Escherichia coli | Nature Communications | 2021 | ISSN 2041-1723 |
| Guo, Shuyu et al. | Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development | Theranostics | 2021 | ISSN 1838-7640 |
| Wang, Junyi et al. | Rho-GEF Trio regulates osteosarcoma progression and osteogenic differentiation through Rac1 and RhoA | Cell Death and Disease | 2021 | ISSN 2041-4889 |
| Zhan, Fangbiao et al. | RhoA enhances osteosarcoma resistance to MPPa-PDT via the Hippo/YAP signaling pathway | Cell and Bioscience | 2021 | ISSN 2045-3701 |
| Chen, Lei et al. | The adenosine A2A receptor alleviates postoperative delirium-like behaviors by restoring blood cerebrospinal barrier permeability in rats | Journal of Neurochemistry | 2021 | ISSN 1471-4159 |
| Ko, Eunsun et al. | Nrf2 regulates cell motility through RhoA–ROCK1 signalling in non-small-cell lung cancer cells | Scientific Reports | 2021 | ISSN 2045-2322 |
| Nishiyama, Kanako et al. | CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP | Life Science Alliance | 2021 | ISSN 2575-1077 |
| Sharma, Pawan et al. | Diacylglycerol kinase inhibition reduces airway contraction by negative feedback regulation of gq-signaling | American Journal of Respiratory Cell and Molecular Biology | 2021 | ISSN 1535-4989 |
| Agbaegbu Iweka, Chinyere et al. | The lipid phosphatase-like protein PLPPR1 associates with RhoGDI1 to modulate RhoA activation in response to axon growth inhibitory molecules | Journal of Neurochemistry | 2021 | ISSN 1471-4159 |
| De Belly, Henry et al. | Membrane Tension Gates ERK-Mediated Regulation of Pluripotent Cell Fate | Cell Stem Cell | 2021 | ISSN 1875-9777 |
| Rolle, Irene Giulia et al. | Heart failure impairs the mechanotransduction properties of human cardiac pericytes | Journal of Molecular and Cellular Cardiology | 2021 | ISSN 0022--2828 |
| Wang, Ying et al. | Murine epsins play an integral role in podocyte function | Journal of the American Society of Nephrology | 2020 | ISSN 1533-3450 |
| Wee, Kenneth et al. | Snail induces epithelial cell extrusion by regulating RhoA contractile signalling and cell–matrix adhesion | Journal of Cell Science | 2020 | ISSN 1477-9137 |
| Wang, Xiaobo et al. | Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis | Cell Metabolism | 2020 | ISSN 1932-7420 |
| Hellinger, Johanna W. et al. | Identification of drivers of breast cancer invasion by secretome analysis: insight into CTGF signaling | Scientific Reports | 2020 | ISSN 2045-2322 |
| Kitchen, Gareth B. et al. | The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia | Proceedings of the National Academy of Sciences of the United States of America | 2020 | ISSN 1091-6490 |
| Wang, Ruixiao et al. | Rac1 silencing, NSC23766 and EHT1864 reduce growth and actin organization of bladder smooth muscle cells | Life Sciences | 2020 | ISSN 1879-0631 |
| Moodley, Serisha et al. | RET isoform-specific interaction with scaffold protein Ezrin promotes cell migration and chemotaxis in lung adenocarcinoma | Lung cancer (Amsterdam, Netherlands) | 2020 | ISSN 1872--8332 |
| Kumagai, Shogo et al. | An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells | Immunity | 2020 | ISSN 1097-4180 |
| Barabutis, Nektarios et al. | Protective mechanism of the selective vasopressin V1A receptor agonist selepressin against endothelial barrier dysfunction | Journal of Pharmacology and Experimental Therapeutics | 2020 | ISSN 1521-0103 |
| Wang, Qinglian et al. | Thymol alleviates AGEs-induced podocyte injury by a pleiotropic effect via NF-κB-mediated by RhoA/ROCK signalling pathway | Cell Adhesion and Migration | 2020 | ISSN 1933-6926 |
| Guo, Yaxiu et al. | Cytotoxic necrotizing factor 1 promotes bladder cancer angiogenesis through activating RhoC | FASEB Journal | 2020 | ISSN 1530-6860 |
| Ramírez-Ramírez, Danelia et al. | Rac1 is necessary for capacitation and acrosome reaction in guinea pig spermatozoa | Journal of cellular biochemistry | 2020 | ISSN 1097--4644 |
| Grun, Daniel et al. | NRP-1 interacts with GIPC1 and SYX to activate p38 MAPK signaling and cancer stem cell survival | Molecular Carcinogenesis | 2019 | ISSN 1098-2744 |
| Akula, Murali K. et al. | Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions | Nature Communications | 2019 | ISSN 2041-1723 |
| Schipper, Koen et al. | Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin | Nature Communications | 2019 | ISSN 2041-1723 |
| Jiao, Yi et al. | Mechanism of H2S‑mediated ROCK inhibition of total flavones of Rhododendra against myocardial ischemia injury | Experimental and Therapeutic Medicine | 2019 | ISSN 1792--0981 |
| Tanga, Naomi et al. | The PTN-PTPRZ signal activates the AFAP1L2-dependent PI3K-AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice | Glia | 2019 | ISSN 1098-1136 |
| Yu, Minhao et al. | Increased proton-sensing receptor GPR4 signalling promotes colorectal cancer progression by activating the hippo pathway | EBioMedicine | 2019 | ISSN 2352-3964 |
| Lee, Sung Kyoung et al. | Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity | Cell Reports | 2018 | ISSN 2211-1247 |
| Cai, Jing et al. | A RhoA–YAP–c-Myc signaling axis promotes the development of polycystic kidney disease | Genes and Development | 2018 | ISSN 1549-5477 |
| Zhang, Xin et al. | Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2 | Cell Death and Disease | 2018 | ISSN 2041-4889 |
| Ma, Teng jiao et al. | CLOCK and BMAL1 stabilize and activate RHOA to promote F-actin formation in cancer cells | Experimental and Molecular Medicine | 2018 | ISSN 2092-6413 |
| Brauer, Philip R. et al. | Krüppel-like factor 4 mediates cellular migration and invasion by altering RhoA activity | Cell Communication and Adhesion | 2018 | ISSN 1543-5180 |
| Zhang, Lei et al. | Calcium-Sensing Receptor Stimulation in Cultured Glomerular Podocytes Induces TRPC6-Dependent Calcium Entry and RhoA Activation | Cellular Physiology and Biochemistry | 2018 | ISSN 1421-9778 |
| Lehman, Heather L. et al. | NFkB hyperactivation causes invasion of esophageal squamous cell carcinoma with EGFR overexpression and p120-catenin down-regulation | Oncotarget | 2018 | ISSN 1949-2553 |
| Haemmerle, Monika et al. | Platelets reduce anoikis and promote metastasis by activating YAP1 signaling | Nature Communications | 2017 | ISSN 2041-1723 |
| Goodman, Linda et al. | Integrin α8 and Pcdh15 act as a complex to regulate cilia biogenesis in sensory cells | Journal of Cell Science | 2017 | ISSN 1477-9137 |
| Xue, Li et al. | Duration of simulated microgravity affects the differentiation of mesenchymal stem cells | Molecular Medicine Reports | 2017 | ISSN 1791-3004 |
| Islam, Salman Ul et al. | PRPF overexpression induces drug resistance through actin cytoskeleton rearrangement and epithelial-mesenchymal transition | Oncotarget | 2017 | ISSN 1949-2553 |
| Cho, Soo Young et al. | Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers | Gastroenterology | 2017 | ISSN 1528-0012 |
| Watts, Bruns A. et al. | High-mobility group box 1 inhibits HCO3_ absorption in the medullary thick ascending limb through RAGE-rho-ROCK-mediated inhibition of basolateral Na+/H+ exchange | American Journal of Physiology - Renal Physiology | 2016 | ISSN 1522-1466 |
| Gilbert, James et al. | The X-linked autism protein KIAA2022/KIDLIA regulates neurite outgrowth via N-cadherin and δ-catenin signaling | eNeuro | 2016 | ISSN 2373-2822 |
| Priya, Rashmi et al. | Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions | Nature Cell Biology | 2015 | ISSN 1476-4679 |
| Wang, Y. et al. | Inhibition of prostate smooth muscle contraction and prostate stromal cell growth by the inhibitors of Rac, NSC23766 and EHT1864 | British Journal of Pharmacology | 2015 | ISSN 1476-5381 |
| Du, Chang Qing et al. | Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced fibrotic responses in vascular smooth muscle cells | International Journal of Molecular Medicine | 2015 | ISSN 1791-244X |
| Parker, William H. et al. | Intracellular sscorbate prevents endothelial barrier permeabilization by thrombin | Journal of Biological Chemistry | 2015 | ISSN 1083-351X |
| Inoue-Mochita, Miyuki et al. | P38 MAP kinase inhibitor suppresses transforming growth factor-β2-induced type 1 collagen production in trabecular meshwork cells | PLoS ONE | 2015 | ISSN 1932-6203 |
| Wang, Shi Jie et al. | CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells | Oncotarget | 2015 | ISSN 1949-2553 |
| Su, Chien Chia et al. | Phenotypes of trypsin- and collagenase-prepared bovine corneal endothelial cells in the presence of a selective rho kinase inhibitor, Y-27632 | Molecular Vision | 2015 | ISSN 1090-0535 |
| Stankiewicz, Trisha R. et al. | Rho family GTPases: Key players in neuronal development, neuronal survival, and neurodegeneration | Frontiers in Cellular Neuroscience | 2014 | ISSN 1662-5102 |
| Yan, Chao et al. | Discovery and characterization of small molecules that target the GTPase Ral | 2014 | ISSN 1476--4687 | |
| Xie, Xi et al. | Activation of RhoA/ROCK regulates NF-κB signaling pathway in experimental diabetic nephropathy | Molecular and cellular endocrinology | 2013 | ISSN 1872--8057 |
| Zhan, Hong et al. | The effect of an NgR1 antagonist on the neuroprotection of cortical axons after cortical infarction in rats | Neurochemical Research | 2013 | ISSN 0364-3190 |
| Hara, Yusuke et al. | Directional migration of leading-edge mesoderm generates physical forces: Implication in Xenopus notochord formation during gastrulation | Developmental Biology | 2013 | ISSN 1095-564X |
| Xu, Jie et al. | RhoGAPs Attenuate Cell Proliferation by Direct Interaction with p53 Tetramerization Domain | Cell Reports | 2013 | ISSN 2211-1247 |
| Tsuboi, Naoko et al. | The effect of monocyte chemoattractant protein-1/CC chemokine ligand 2 on aqueous humor outflow facility | Investigative Ophthalmology and Visual Science | 2012 | ISSN 0146-0404 |
| Nithipatikom, Kasem et al. | Cannabinoid receptor type 1 (CB1) activation inhibits small GTPase RhoA activity and regulates motility of prostate carcinoma cells | Endocrinology | 2012 | ISSN 1945--7170 |
| Lee, Wonhwa et al. | Barrier protective effects of withaferin A in HMGB1-induced inflammatory responses in both cellular and animal models | Toxicology and applied pharmacology | 2012 | ISSN 1096--0333 |
| Dong, Ming et al. | Increased Rho kinase activity in congestive heart failure | European Journal of Heart Failure | 2012 | ISSN 1388-9842 |
| Cheng, Haoran et al. | Infrasonic noise induces axonal degeneration of cultured neurons via a Ca²⁺ influx pathway | Toxicology letters | 2012 | ISSN 1879--3169 |
| Gastonguay, Adam et al. | The role of Rac1 in the regulation of NF-kB activity, cell proliferation, and cell migration in non-small cell lung carcinoma | Cancer Biology & Therapy | 2012 | ISSN 1538--4047 |
| Li, B. et al. | RhoA triggers a specific signaling pathway that generates transforming microvesicles in cancer cells | Oncogene | 2012 | ISSN 1476--5594 |
| Eitaki, Masato et al. | Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cells | BMC Cancer | 2012 | ISSN 1471-2407 |
| Borah, Sapan et al. | The Rho1 GTPase-activating protein CgBem2 is required for survival of azole stress in Candida glabrata | Journal of Biological Chemistry | 2011 | ISSN 0021-9258 |
| Khan, Omar M. et al. | Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice | Journal of Clinical Investigation | 2011 | ISSN 0021-9738 |
| Balanis, Nikolas et al. | β3 integrin-EGF receptor cross-talk activates p190RhoGAP in mouse mammary gland epithelial cells | Molecular Biology of the Cell | 2011 | ISSN 1059-1524 |
| Hu, Yi et al. | Effects of ischemic preconditioning on vascular reactivity and calcium sensitivity after hemorrhagic shock and their relationship to the RhoA–Rho-kinase pathway in rats | Journal of cardiovascular pharmacology | 2011 | ISSN 1533--4023 |
| Du, Hui et al. | Phenylephrine induces elevated RhoA activation and smooth muscle α-actin expression in Pkd2+/-vascular smooth muscle cells | Hypertension Research | 2010 | ISSN 0916-9636 |
| Xing, Dongmei et al. | Effect of cAMP on TGFβ1-induced corneal keratocyte-myofibroblast transformation | Investigative Ophthalmology and Visual Science | 2009 | ISSN 0146-0404 |
| Xing, Dongmei et al. | Hypoxia reduces TGFβ1-induced corneal keratocyte myofibroblast transformation | Molecular Vision | 2009 | ISSN 1090-0535 |
| Ríos, Amelia et al. | Participation of Rho, ROCK-2, and GAP activities during actin microfilament rearrangements in Entamoeba histolytica induced by fibronectin signaling | Cell Biology International | 2008 | ISSN 1065-6995 |
| Cheng, Zhi Jie et al. | Distinct mechanisms of clathrin-independent endocytosis have unique sphingolipid requirements | Molecular Biology of the Cell | 2006 | ISSN 1059-1524 |
| Pixley, Fiona J. et al. | BCL6 suppresses RhoA activity to alter macrophage morphology and motility | Journal of cell science | 2005 | ISSN 0021--9533 |
| Sasai, Noriaki et al. | The neurotrophin-receptor-related protein NRH1 is essential for convergent extension movements | 2004 | PMID 15258592 | |
| Birukova, Anna A. et al. | Protein kinase A attenuates endothelial cell barrier dysfunction induced by microtubule disassembly | American journal of physiology. Lung cellular and molecular physiology | 2004 | ISSN 1040--0605 |
| Cetin, Selma et al. | Endotoxin inhibits intestinal epithelial restitution through activation of Rho-GTPase and increased focal adhesions | The Journal of biological chemistry | 2004 | ISSN 0021--9258 |
| Yang, Seun Ah et al. | Rho and Rho-kinase mediate thrombin-induced phosphatidylinositol 4-phosphate 5-kinase trafficking in platelets | Journal of Biological Chemistry | 2004 | ISSN 0021-9258 |
| Orr, Anthony Wayne et al. | Thrombospondin Induces RhoA Inactivation through FAK-dependent Signaling to Stimulate Focal Adhesion Disassembly | Journal of Biological Chemistry | 2004 | ISSN 0021--9258 |
| Setiadi, Hendra et al. | Signal-dependent distribution of cell surface P-selectin in clathrin-coated pits affects leukocyte rolling under flow | Journal of Cell Biology | 2003 | ISSN 0021--9525 |
| Activation of RhoA in Alcohol-Induced Intestinal Barrier Dysfunction | Request PDF | Article Link |
| Author | Title | Journal | Year | Article Link |
|---|---|---|---|---|
| Leguay, Kévin et al. | Interphase microtubule disassembly is a signaling cue that drives cell rounding at mitotic entry | Journal of Cell Biology | 2022 | ISSN 1540-8140 |
| Khan, Alamzeb et al. | ArhGEF12 activates Rap1A and not RhoA in human dermal microvascular endothelial cells to reduce tumor necrosis factor-induced leak | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 2022 | ISSN 1530-6860 |
| You, Jae Sung et al. | ARHGEF3 Regulates Skeletal Muscle Regeneration and Strength through Autophagy | Cell Reports | 2021 | ISSN 2211-1247 |
| Afanasyeva, Elena A. et al. | Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma | Life Science Alliance | 2021 | ISSN 2575-1077 |
| Liang, Xiaoting et al. | Acetylation dependent functions of Rab22a-NeoF1 Fusion Protein in Osteosarcoma | Theranostics | 2020 | ISSN 1838-7640 |
| Addis, Dylan R. et al. | Vascular permeability disruption explored in the proteomes of mouse lungs and human microvascular cells following acute bromine exposure | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2020 | ISSN 1522-1504 |
| Evans, Frances et al. | Signaling pathways in cytoskeletal responses to plasma membrane depolarization in corneal endothelial cells | Journal of Cellular Physiology | 2020 | ISSN 1097-4652 |
| Huang, Yuxing et al. | Arp2/3-branched actin maintains an active pool of GTP-RhoA and controls RhoA abundance | Cells | 2019 | ISSN 2073-4409 |
| Choi, Michael Y. et al. | Phase I Trial: Cirmtuzumab Inhibits ROR1 Signaling and Stemness Signatures in Patients with Chronic Lymphocytic Leukemia | Cell Stem Cell | 2018 | ISSN 1875-9777 |
| Yu, Lixia et al. | C-Maf inducing protein inhibits coflin-1 activity and alters podocyte cytoskeleton organization | Molecular Medicine Reports | 2017 | ISSN 1791-3004 |
| Kempf, Anissa et al. | Control of Cell Shape, Neurite Outgrowth, and Migration by a Nogo-A/HSPG Interaction | Developmental Cell | 2017 | ISSN 1878-1551 |
| Li, Shufeng et al. | Microtopographical features generated by photopolymerization recruit RhoA/ROCK through TRPV1 to direct cell and neurite growth | Biomaterials | 2015 | ISSN 1878-5905 |
| Gray, Jason D. et al. | LRP6 exerts non-canonical effects on Wnt signaling during neural tube closure | Human Molecular Genetics | 2013 | ISSN 0964-6906 |
| Xu, Jie et al. | RhoGAPs Attenuate Cell Proliferation by Direct Interaction with p53 Tetramerization Domain | Cell Reports | 2013 | ISSN 2211-1247 |
| Buranda, Tione et al. | Rapid parallel flow cytometry assays of active GTPases using effector beads | Analytical Biochemistry | 2013 | ISSN 1096-0309 |
| Sabbatini, Maria Eugenia et al. | Cholecystokinin-Mediated RhoGDI Phosphorylation via PKCα Promotes both RhoA and Rac1 Signaling | PLoS ONE | 2013 | ISSN 1932-6203 |
| Zhang, Y. et al. | High glucose-induced RhoA activation requires caveolae and PKCβ1-mediated ROS generation | American journal of physiology. Renal physiology | 2012 | ISSN 1522--1466 |
| Ponsaerts, Raf et al. | RhoA GTPase switch controls Cx43-hemichannel activity through the contractile system | PLoS ONE | 2012 | ISSN 1932-6203 |
| Cartier-Michaud, Amandine et al. | Matrix-bound PAI-1 supports cell blebbing via RhoA/rock1 signaling | PLoS ONE | 2012 | ISSN 1932-6203 |
| Kyrkou, A. et al. | RhoD participates in the regulation of cell-cycle progression and centrosome duplication | Oncogene 2013 32:14 | 2012 | ISSN 1476--5594 |
| Ladhani, Omar et al. | Pigment Epithelium-Derived Factor Blocks Tumor Extravasation by Suppressing Amoeboid Morphology and Mesenchymal Proteolysis | Neoplasia (New York, N.Y.) | 2011 | ISSN 1476-5586 |
| Chacon, Pedro J. et al. | Inhibition of RhoA GTPase and the subsequent activation of PTP1B protects cultured hippocampal neurons against amyloid β toxicity | Molecular Neurodegeneration | 2011 | ISSN 1750-1326 |
| Bi, Yan et al. | A role for Rho and Rac in secretagogue-induced amylase release by pancreatic acini | American journal of physiology. Cell physiology | 2005 | ISSN 0363--6143 |
| Ishii, Satoshi et al. | Identification of T cell death-associated gene 8 (TDAG8) as a novel acid sensing G-protein-coupled receptor | The Journal of biological chemistry | 2005 | ISSN 0021--9258 |
| Wang, Shizhen Emily et al. | Transforming Growth Factor β (TGF-β)-Smad Target Gene Protein Tyrosine Phosphatase Receptor Type Kappa Is Required for TGF-β Function | Molecular and Cellular Biology | 2005 | ISSN 0270--7306 |
| Saito, Shin'ichi et al. | Deregulation and mislocalization of the cytokinesis regulator ECT2 activate the Rho signaling pathways leading to malignant transformation | The Journal of biological chemistry | 2004 | ISSN 0021--9258 |
| Wang, Qin et al. | Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells | The Journal of biological chemistry | 2004 | ISSN 0021--9258 |
| Zhang, Xiao Feng et al. | Rho-Dependent Contractile Responses in the Neuronal Growth Cone Are Independent of Classical Peripheral Retrograde Actin Flow | Neuron | 2003 | ISSN 0896-6273 |