Cytoskeleton Inc Activation Assay Validation Data and Citations

Activation Assay Citations

AuthorTitleJournalYearArticle Link
Gao, Fei et al.STARD13 is positively correlated with good prognosis and enhances 5-FU sensitivity via suppressing cancer stemness in hepatocellular carcinoma cellsOncoTargets and Therapy2018ISSN 1178-6930
Rafiq, Nisha Bte Mohd et al.Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNOThe Journal of cell biology2017ISSN 1540--8140
Rennoll-Bankert, Kristen E. et al.RalF-Mediated Activation of Arf6 ControlsRickettsia typhiInvasionby Co-Opting Phosphoinositol MetabolismInfect Immun2016PMID 27698019
Schultz, Mark L. et al.CLN3 Deficient Cells Display Defects in the ARF1-Cdc42 Pathway and Actin-Dependent EventsPLOS ONE2014ISSN 1932--6203
AuthorTitleJournalYearArticle Link
Borghesan, Elizabeth et al. A Brucella effector modulates the Arf6‐Rab8a GTPase cascade to promote intravacuolar replication The EMBO Journal2021ISSN 0261--4189
Jackson, Matilda R. et al.Heterozygous loss of function of IQSEC2/Iqsec2 leads to increased activated Arf6 and severe neurocognitive seizure phenotype in femalesLife Science Alliance2019ISSN 2575-1077
Rafiq, Nisha Bte Mohd et al.Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNOThe Journal of cell biology2017ISSN 1540--8140
Stepicheva, Nadezda A. et al.The small GTPase Arf6 regulates sea urchin morphogenesisDifferentiation; research in biological diversity2017ISSN 1432-0436
Biesemann, Anja et al.Rab35 protein regulates evoked exocytosis of endothelial Weibel-Palade bodiesThe Journal of biological chemistry2017ISSN 1083--351X
Rennoll-Bankert, Kristen E. et al.RalF-Mediated Activation of Arf6 ControlsRickettsia typhiInvasionby Co-Opting Phosphoinositol MetabolismInfect Immun2016PMID 27698019
Andrews, Allison M. et al.Mechanical Injury Induces Brain Endothelial-Derived Microvesicle Release: Implications for Cerebral Vascular Injury during Traumatic Brain InjuryFrontiers in Cellular Neuroscience2016ISSN 1662-5102
Marchesin, Valentina et al.ARF6 promotes the formation of Rac1 and WAVE-dependent ventral F-Actin rosettes in breast cancer cells in response to epidermal growth factorPLoS ONE2015ISSN 1932-6203
AuthorTitleJournalYearArticle Link
Liang, Bishan et al.Cdc42-driven endosomal cholesterol transport promotes collateral resistance in HER2-positive gastric cancerCancer Letters2024ISSN 0304--3835
St. Paul, Amanda et al.FXR1 regulates vascular smooth muscle cell cytoskeleton, VSMC contractility, and blood pressure by multiple mechanismsCell reports2023ISSN 2211-1247
Castillo-Azofeifa, David et al.A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signalingCell stem cell2023ISSN 1875--9777
Crespo, Grace Velez et al.The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancerMolecular Medicine2023ISSN 1528-3658
Zi, Jingjing et al.PFN1 Inhibits Myogenesis of Bovine Myoblast Cells via Cdc42-PAK/JNKCells2022ISSN 2073-4409
Meng, Zhipeng et al.The Hippo pathway mediates Semaphorin signalingScience Advances2022ISSN 2375-2548
Jiang, Ruiwei et al.CDC42 governs normal oviduct multiciliogenesis through activating AKT to ensure timely embryo transportCell Death & Disease 2022 13:92022ISSN 2041--4889
Ma, Yuanyuan et al.Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during tooth root developmentDevelopment (Cambridge)2021ISSN 1477-9129
Jozic, Ivan et al.Glucocorticoid-mediated induction of caveolin-1 disrupts cytoskeletal organization, inhibits cell migration and re-epithelialization of non-healing woundsCommunications Biology2021ISSN 2399-3642
Vallejo, Daniela et al.Wnt5a modulates dendritic spine dynamics through the regulation of Cofilin via small Rho GTPase activity in hippocampal neuronsJournal of Neurochemistry2021ISSN 1471-4159
Wurzer, Hannah et al.Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome In Vitro by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton RemodelingFrontiers in Immunology2021ISSN 1664-3224
Merlin, Johanna et al.Non-canonical glutamine transamination sustains efferocytosis by coupling redox buffering to oxidative phosphorylationNature Metabolism2021ISSN 2522-5812
Lee, DanielmiR‑769‑5p is associated with prostate cancer recurrence and modulates proliferation and apoptosis of cancer cellsExperimental and Therapeutic Medicine2021ISSN 1792--0981
Salameh, Joëlle et al.Cdc42 and its BORG2 and BORG3 effectors control the subcellular localization of septins between actin stress fibers and microtubulesCurrent Biology2021ISSN 1879-0445
Talamás-Lara, Daniel et al.Entamoeba histolytica and Entamoeba dispar: Morphological and Behavioral Differences Induced by Fibronectin through GTPases Activation and Actin-Binding ProteinsThe Journal of eukaryotic microbiology2020ISSN 1550--7408
Krueger, Irena et al.Reelin amplifies glycoprotein VI activation and alphaiib beta3 integrin outside-in signaling via PLC Gamma 2 and Rho GTPasesArteriosclerosis, Thrombosis, and Vascular Biology2020ISSN 1524-4636
Rong, Zhouyi et al.Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aβ42 in triggering receptor expressed on myeloid cells 2 loss-of-function murine modelsFASEB Journal2020ISSN 1530-6860
Andrews, Madeline G. et al.Mtor signaling regulates the morphology and migration of outer radial glia in developing human cortexeLife2020ISSN 2050-084X
Choraghe, Rohan P. et al.RHOA-mediated mechanical force generation through Dectin-1Journal of cell science2020ISSN 1477-9137
Malek, Natalia et al.Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) technique shows that non-muscle β and γ actin are not equal in relation to human melanoma cells’ motility and focal adhesion formationInternational Journal of Molecular Sciences2020ISSN 1422-0067
Wilson, Kitchener D. et al.Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human PrimatesDevelopmental Cell2020ISSN 1878-1551
Reyes-Miguel, Tania et al.CDC42 drives RHOA activity and actin polymerization during capacitationReproduction2020ISSN 1741-7899
Ursino, Gloria M et al.ABCA12 regulates insulin secretion from β‐cellsEMBO reports2020ISSN 1469--221X
Novak, Caymen M. et al.Compressive stimulation enhances ovarian cancer proliferation, invasion, chemoresistance, and mechanotransduction via cdc42 in a 3d bioreactorCancers2020ISSN 2072-6694
Wu, Huijuan et al.Progressive Pulmonary Fibrosis Is Caused by Elevated Mechanical Tension on Alveolar Stem CellsCell2020ISSN 1097-4172
Zhang, Xiao et al.Elevating EGFR-MAPK program by a nonconventional Cdc42 enhances intestinal epithelial survival and regenerationJCI Insight2020ISSN 2379-3708
Gorisse, Laetitia et al.Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42Journal of Biological Chemistry2020ISSN 1083-351X
Zanin, Juan P. et al.The p75NTR influences cerebellar circuit development and adult behavior via regulation of cell cycle duration of granule cell progenitorsJournal of Neuroscience2019ISSN 1529-2401
Wu, Xuping et al.Wnt5a induces ROR1 and ROR2 to activate RhoA in esophageal squamous cell carcinoma cellsCancer Management and Research2019ISSN 1179-1322
Santhana Kumar, Karthiga et al.TGF-β Determines the Pro-migratory Potential of bFGF Signaling in MedulloblastomaCell Reports2018ISSN 2211-1247
Yan, Ting et al.Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cellsJournal of Biological Chemistry2018ISSN 1083-351X
Suraneni, Praveen K. et al.Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activityBlood Advances2018ISSN 2473-9537
Mayer, Louisa et al.Nbeal2 interacts with Dock7, Sec16a, and Vac14Blood2018ISSN 1528-0020
Veluthakal, Rajakrishnan et al.Restoration of glucose-stimulated Cdc42-PAK1 activation and insulin secretion by a selective Epac activator in type 2 diabetic human isletsDiabetes2018ISSN 1939-327X
Gu, Changkyu et al.Dynamin autonomously regulates podocyte focal adhesion maturationJournal of the American Society of Nephrology2017ISSN 1533-3450
Ruggiero, Carmen et al.Dosage-dependent regulation of VAV2 expression by steroidogenic factor-1 drives adrenocortical carcinoma cell invasionScience Signaling2017ISSN 1937-9145
Kim, Jongshin et al.YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturationJournal of Clinical Investigation2017ISSN 1558-8238
Xiao, Bin et al.Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signalingOncotarget2016ISSN 1949-2553
Jones, Eleanor L. et al.Dendritic Cell Migration and Antigen Presentation Are Coordinated by the Opposing Functions of the Tetraspanins CD82 and CD37The Journal of Immunology2016ISSN 0022--1767
Sroka, Jolanta et al.Lamellipodia and membrane blebs drive efficient electrotactic migration of rat walker carcinosarcoma cells WC 256PLoS ONE2016ISSN 1932-6203
Zhao, Chen Ze et al.Inhibition of farnesyl pyrophosphate synthase improves pressure overload induced chronic cardiac remodelingScientific Reports2016ISSN 2045-2322
Tien, Sui Chih et al.The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42Nature Communications2016ISSN 2041-1723
Martins, Rui et al.Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functionsNature Immunology2016ISSN 1529-2916
Herrera-Martínez, Mayra et al.Antiamoebic activity of Adenophyllum aurantium (L.) strother and its effect on the actin cytoskeleton of Entamoeba histolyticaFrontiers in Pharmacology2016ISSN 1663-9812
Ochoa-Alvarez, Jhon A. et al.Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanismsOncotarget2015ISSN 1949-2553
Guo, Yuna et al.A novel pharmacologic activity of ketorolac for therapeutic benefit in ovarian cancer patientsClinical Cancer Research2015ISSN 1557-3265
Breslin, Jerome W. et al.Involvement of local lamellipodia in endothelial barrier functionPLoS ONE2015ISSN 1932-6203
Yan, Yi et al.Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5Nature Communications2015ISSN 2041-1723
Hanin, Geula et al.Competing targets of microRNA-608 affect anxiety and hypertensionHuman Molecular Genetics2014ISSN 1460-2083
Ahn, Bum Ju et al.Ninjurin1 enhances the basal motility and transendothelial migration of immune cells by inducing protrusive membrane dynamicsJournal of Biological Chemistry2014ISSN 1083-351X
Rigano, Luciano A. et al.Listeria monocytogenes antagonizes the human GTPase Cdc42 to promote bacterial spreadCellular Microbiology2014ISSN 1462-5822
Chakravarti, Bandana et al.Thioaryl naphthylmethanone oxime ether analogs as novel anticancer agentsJournal of Medicinal Chemistry2014ISSN 1520-4804
Kalia, Manjula et al.Japanese Encephalitis Virus Infects Neuronal Cells through a Clathrin-Independent Endocytic MechanismJournal of Virology2013ISSN 0022--538X
Yao, Honghong et al.Nonmuscle myosin light-chain kinase mediates microglial migration induced by HIV Tat: involvement of β1 integrinsFASEB journal : official publication of the Federation of American Societies for Experimental Biology2013ISSN 1530--6860
Dubash, Adi D. et al.The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1Journal of Cell Biology2013ISSN 0021-9525
Ramsay, Alan G. et al.Chronic lymphocytic leukemia cells induce defective LFA-1-directed T-cell motility by altering Rho GTPase signaling that is reversible with lenali******Blood2013ISSN 1528-0020
Bray, Kristi et al.Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migrationBreast Cancer Research2013ISSN 1465-5411
Chen, Bin et al.Alteration of mevalonate pathway related enzyme expressions in pressure overload-induced cardiac hypertrophy and associated heart failure with preserved ejection fractionCellular Physiology and Biochemistry2013ISSN 1421-9778
Yang, Jian et al.Cardiac-specific overexpression of farnesyl pyrophosphate synthase induces cardiac hypertrophy and dysfunction in miceCardiovascular Research2013ISSN 0008-6363
Valtcheva, Nadejda et al.The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42Journal of Biological Chemistry2013ISSN 0021-9258
Barrio, Laura et al.TLR4 Signaling Shapes B Cell Dynamics via MyD88-Dependent Pathways and Rac GTPasesThe Journal of Immunology2013ISSN 0022--1767
Chen, Guang et al.Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells (Journal of Biological Chemistry (2012) 2Journal of Biological Chemistry2012ISSN 0021-9258
Dhaliwal, Anandika et al.Cellular Cytoskeleton Dynamics Modulates Non-Viral Gene Delivery through RhoGTPases2012PMID 22509380
Eggers, Carrie M. et al.STE20-related kinase adaptor protein α (STRADα) regulates cell polarity and invasion through PAK1 signaling in LKB1-null cellsThe Journal of biological chemistry2012ISSN 1083--351X
Ramsay, Alan G. et al.Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenali******: Establishing a reversible immune evasion mechanism in human cancerBlood2012ISSN 1528-0020
Chen, Si Meng et al.Inhibition of tumor cell growth, proliferation and migration by X-387, a novel active-site inhibitor of mTORBiochemical Pharmacology2012ISSN 0006-2952
Elali, Ayman et al.Liver X receptor activation enhances blood-brain barrier integrity in the ischemic brain and increases the abundance of ATP-binding cassette transporters ABCB1 and ABCC1 on brain capillary cellsBrain Pathology2012ISSN 1015-6305
Martin-Granados, Cristina et al.A role for PP1/NIPP1 in steering migration of human cancer cellsPLoS ONE2012ISSN 1932-6203
Lichtenstein, Mathieu P. et al.Secretase-independent and RhoGTPase/PAK/ERK-dependent regulation of cytoskeleton dynamics in astrocytes by NSAIDs and derivativesJournal of Alzheimer's disease : JAD2010ISSN 1875--8908
McHenry, Peter R. et al.P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasisBreast Cancer Research2010ISSN 1465-5411
Romero, Ana M. et al.Chronic ethanol exposure alters the levels, assembly, and cellular organization of the actin cytoskeleton and microtubules in hippocampal neurons in primary cultureToxicological Sciences2010ISSN 1096-6080
Stankiewicz, Traci E. et al.GTPase activating protein function of p85 facilitates uptake and recycling of the β1 integrinBiochemical and biophysical research communications2010ISSN 0006-291X
Heckman-Stoddard, Brandy M. et al.Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression2009ISSN 1465-5411
Schlegel, Nicolas et al.Impaired cAMP and Rac 1 signaling contribute to TNF-alpha-induced endothelial barrier breakdown in microvascular endotheliumMicrocirculation (New York, N.Y. : 1994)2009ISSN 1549--8719
AuthorTitleJournalYearArticle Link
He, Yi et al.CdGAP is a talin-binding protein and a target of TGF-β signaling that promotes HER2-positive breast cancer growth and metastasisCell reports2023ISSN 2211--1247
Phuyal, Santosh et al.Mechanical strain stimulates COPII-dependent secretory trafficking via Rac1The EMBO Journal2022ISSN 1460--2075
Nath, Anu S. et al.Modulation of the cell membrane lipid milieu by peroxisomal β-oxidation induces Rho1 signaling to trigger inflammatory responsesCell Reports2022ISSN 2211-1247
Turgu, Busra et al.HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent mannerOncogene2021ISSN 1476-5594
Garitano-Trojaola, Andoni et al.Actin cytoskeleton deregulation confers midostaurin resistance in FLT3-mutant acute myeloid leukemiaCommunications biology2021ISSN 2399-3642
Zhu, Bili et al.Lipid oversupply induces CD36 sarcolemmal translocation via dual modulation of PKCζ and TBC1D1: An early event prior to insulin resistanceTheranostics2020ISSN 1838-7640
Berthenet, Kevin et al.Failed Apoptosis Enhances Melanoma Cancer Cell AggressivenessCell Reports2020ISSN 2211-1247
Crawford, Melissa et al.Essential Role for Integrin-Linked Kinase in Melanoblast Colonization of the SkinJournal of Investigative Dermatology2020ISSN 1523-1747
Elshaer, Sally L. et al.Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinal vascular permeability in mice via inhibition of inflammation and the RhoA kinase pathwayDiabetologia2019ISSN 1432-0428
El-Naggar, Amal M. et al.HACE1 is a potential tumor suppressor in osteosarcomaCell Death and Disease2019ISSN 2041-4889
Yan, Ting et al.Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cellsJournal of Biological Chemistry2018ISSN 1083-351X
Kang, Jeong Hun et al.Protein kinase Cα as a therapeutic target in cancerProtein Kinase C: Emerging Roles and Therapeutic Potential2018Article Link
Kai, Masahiro et al.Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancerMolecular Carcinogenesis2017ISSN 1098-2744
Jeong, Suk Yeong et al.Loss of Tpm4.1 leads to disruption of cell-cell adhesions and invasive behavior in breast epithelial cells via increased Rac1 signalingOncotarget2017ISSN 1949-2553
Ruggiero, Carmen et al.Dosage-dependent regulation of VAV2 expression by steroidogenic factor-1 drives adrenocortical carcinoma cell invasionScience Signaling2017ISSN 1937-9145
Kim, Jongshin et al.YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturationJournal of Clinical Investigation2017ISSN 1558-8238
Thuault, Sylvie et al.The RhoE/ROCK/ARHGAP25 signaling pathway controls cell invasion by inhibition of Rac activityMolecular Biology of the Cell2016ISSN 1939-4586
Sylow, Lykke et al.Rac1 governs exercise-stimulated glucose uptake in skeletal muscle through regulation of GLUT4 translocation in miceJournal of Physiology2016ISSN 1469-7793
Sarowar, Tasnuva et al.Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2Molecular Brain2016ISSN 1756-6606
Marchesin, Valentina et al.ARF6 promotes the formation of Rac1 and WAVE-dependent ventral F-Actin rosettes in breast cancer cells in response to epidermal growth factorPLoS ONE2015ISSN 1932-6203
Reyes-Reyes, E. Merit et al.Mechanistic studies of anticancer aptamer AS1411 reveal a novel role for nucleolin in regulating Rac1 activationMolecular Oncology2015ISSN 1878-0261
Yan, Yi et al.Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5Nature Communications2015ISSN 2041-1723
Sylow, Lykke et al.Rac1 - a novel regulator of contraction-stimulated glucose uptake in skeletal muscleExperimental Physiology2014ISSN 1469-445X
Radeva, Mariya Y. et al.PKA compartmentalization via AKAP220 and AKAP12 contributes to endothelial barrier regulationPLoS ONE2014ISSN 1932-6203
Nakajima, Chikako et al.The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular developmentDevelopment (Cambridge)2014ISSN 1477-9129
Kikuchi, K. et al.Protein kinase C iota as a therapeutic target in alveolar rhabdomyosarcomaOncogene2013ISSN 1476--5594
Bray, Kristi et al.Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migrationBreast Cancer Research2013ISSN 1465-5411
Sylow, Lykke et al.Rac1 signaling is required for insulin-stimulated glucose uptake and is dysregulated in insulin-resistant murine and human skeletal muscleDiabetes2013ISSN 0012-1797
Redhu, Naresh Singh et al.Thymic stromal lymphopoietin induces migration in human airway smooth muscle cellsScientific Reports2013ISSN 2045-2322
Eggers, Carrie M. et al.STE20-related kinase adaptor protein α (STRADα) regulates cell polarity and invasion through PAK1 signaling in LKB1-null cellsThe Journal of biological chemistry2012ISSN 1083--351X
Sayedyahossein, Samar et al.Essential role of integrin-linked kinase in regulation of phagocytosis in keratinocytesFASEB Journal2012ISSN 1530-6860
Vives, Virginie et al.The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts2011ISSN 1523--4681
Binker, Marcelo G. et al.TGF-β1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-κB/IL-6/MMP-2Biochemical and biophysical research communications2011ISSN 1090--2104
Kigel, Boaz et al.Plexin-A4 promotes tumor progression and tumor angiogenesis by enhancement of VEGF and bFGF signalingBlood2011ISSN 1528-0020
McHenry, Peter R. et al.P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasisBreast Cancer Research2010ISSN 1465-5411
Johanna, Gutiérrez Vargas et al.Rac1 activity changes are associated with neuronal pathology and spatial memory long-term recovery after global cerebral ischemiaNeurochemistry international2010ISSN 1872--9754
Kamai, Takao et al.Increased Rac1 activity and Pak1 overexpression are associated with lymphovascular invasion and lymph node metastasis of upper urinary tract cancerBMC Cancer2010ISSN 1471-2407
Baumer, Y. et al.Role of Rac 1 and cAMP in endothelial barrier stabilization and thrombin-induced barrier breakdownJournal of Cellular Physiology2009ISSN 1097--4652
Heckman-Stoddard, Brandy M. et al.Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression2009ISSN 1465-5411
Chastre, Eric et al.TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasivenessThe FASEB Journal2009ISSN 1530--6860
Moniz, Sónia et al.WNK2 modulates MEK1 activity through the Rho GTPase pathwayCellular signalling2008ISSN 0898--6568
Ramirez, Servio H. et al.Activation of Peroxisome Proliferator-Activated Receptor γ (PPARγ) Suppresses Rho GTPases in Human Brain Microvascular Endothelial Cells and Inhibits Adhesion and Transendothelial Migration of HIV-1 Infected MonocytesThe Journal of Immunology2008ISSN 0022--1767
Petroll, W. Matthew et al.Dynamic assessment of fibroblast mechanical activity during rac-induced cell spreading in 3-D cultureJournal of Cellular Physiology2008ISSN 0021-9541
Pontow, Suzanne et al.Antiviral Activity of a Rac GEF inhibitor Characterized with a Sensitive HIV/SIV Fusion AssayVirology2007ISSN 0042-6822
AuthorTitleJournalYearArticle Link
Moztarzadeh, Sina et al.Cortactin is in a complex with VE-cadherin and is required for endothelial adherens junction stability through Rap1/Rac1 activationScientific Reports 2024 14:12024ISSN 2045--2322
Wang, Yanan et al.PPP2R1A regulates migration persistence through the NHSL1-containing WAVE Shell ComplexNature Communications 2023 14:12023ISSN 2041--1723
Toffali, Lara et al.An isoform of the giant protein titin is a master regulator of human T lymphocyte traffickingCell reports2023ISSN 2211--1247
Turgu, Busra et al. The HACE1 E3 ligase mediates RAC1 ‐dependent control of mTOR signaling complexes EMBO reports2023ISSN 1469--221X
Bartos, Katalin et al.Renal FGF23 signaling depends on redox protein Memo1 and promotes orthovanadate-sensitive protein phosphotyrosyl phosphatase activityJournal of Cell Communication and Signaling2023ISSN 1873-961X
St. Paul, Amanda et al.FXR1 regulates vascular smooth muscle cell cytoskeleton, VSMC contractility, and blood pressure by multiple mechanismsCell reports2023ISSN 2211-1247
Castillo-Azofeifa, David et al.A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signalingCell stem cell2023ISSN 1875--9777
Dang, Iren et al.Key role for Rac in the early transcriptional response to extracellular matrix stiffness and stiffness-dependent repression of ATF3Journal of Cell Science2023ISSN 1477-9137
Tokarz, Victoria L. et al.Palmitate-induced insulin resistance causes actin filament stiffness and GLUT4 mis-sorting without altered Akt signallingJournal of Cell Science2023ISSN 1477-9137
Carbonell, Abigail U. et al.Comparing synaptic proteomes across five mouse models for autism reveals converging molecular similarities including deficits in oxidative phosphorylation and Rho GTPase signalingFrontiers in Aging Neuroscience2023
Crespo, Grace Velez et al.The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancerMolecular Medicine2023ISSN 1528-3658
Darp, Revati et al.Oncogenic BRAF induces whole-genome doubling through suppression of cytokinesisNature Communications 2022 13:12022ISSN 2041--1723
Harms, Julia et al.Pals1 functions in redundancy with SMAP1 to inhibit Arf6 in order to prevent Rac1-dependent colorectal cancer cell migration and invasionCancer Gene Therapy 20222022ISSN 1476--5500
Francis, Caitlin R. et al.Rab35 governs apicobasal polarity through regulation of actin dynamics during sprouting angiogenesisNature Communications 2022 13:12022ISSN 2041--1723
Kim, Seunghoon et al.Investigating the Anti-Inflammatory Effects of RCI001 for Treating Ocular Surface Diseases: Insight Into the Mechanism of ActionFrontiers in Immunology2022
Sugisawa, Erika et al.Nociceptor-derived Reg3γ prevents endotoxic death by targeting kynurenine pathway in microgliaCell Reports2022ISSN 2211-1247
Kim, Seunghoon et al.Investigating the Anti-Inflammatory Effects of RCI001 for Treating Ocular Surface Diseases: Insight Into the Mechanism of ActionFrontiers in Immunology2022ISSN 1664-3224
Ma, Yuanyuan et al.Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during tooth root developmentDevelopment (Cambridge)2021ISSN 1477-9129
Gurusamy, Malarvizhi et al.G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediatorsNature Communications2021ISSN 2041-1723
Kinsella, Sinéad et al.Attenuation of apoptotic cell detection triggers thymic regeneration after damageCell Reports2021ISSN 2211-1247
Mao, De Yu et al.CLIC1 and CLIC4 mediate endothelial S1P receptor signaling to facilitate Rac1 and RhoA activity and functionScience Signaling2021ISSN 1937-9145
Wegscheid, Michelle L. et al.Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesisCell Reports2021ISSN 2211-1247
Vallejo, Daniela et al.Wnt5a modulates dendritic spine dynamics through the regulation of Cofilin via small Rho GTPase activity in hippocampal neuronsJournal of Neurochemistry2021ISSN 1471-4159
Ma, Shang et al.A role of PIEZO1 in iron metabolism in mice and humansCell2021ISSN 1097-4172
Krueger, Irena et al.Reelin amplifies glycoprotein VI activation and alphaiib beta3 integrin outside-in signaling via PLC Gamma 2 and Rho GTPasesArteriosclerosis, Thrombosis, and Vascular Biology2020ISSN 1524-4636
Rong, Zhouyi et al.Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aβ42 in triggering receptor expressed on myeloid cells 2 loss-of-function murine modelsFASEB Journal2020ISSN 1530-6860
Kowluru, Renu A.Retinopathy in a diet-induced type 2 diabetic rat model and role of epigenetic modificationsDiabetes2020ISSN 1939-327X
Andrews, Madeline G. et al.Mtor signaling regulates the morphology and migration of outer radial glia in developing human cortexeLife2020ISSN 2050-084X
Sheftel, Celeste M. et al.Serotonin stimulated parathyroid hormone related protein induction in the mammary epithelia by transglutaminase-dependent serotonylationPLoS ONE2020ISSN 1932-6203
Choraghe, Rohan P. et al.RHOA-mediated mechanical force generation through Dectin-1Journal of cell science2020ISSN 1477-9137
Malek, Natalia et al.Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) technique shows that non-muscle β and γ actin are not equal in relation to human melanoma cells’ motility and focal adhesion formationInternational Journal of Molecular Sciences2020ISSN 1422-0067
Szrejder, Maria et al.Metformin reduces TRPC6 expression through AMPK activation and modulates cytoskeleton dynamics in podocytes under diabetic conditionsBiochimica et Biophysica Acta - Molecular Basis of Disease2020ISSN 1879-260X
Wilson, Kitchener D. et al.Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human PrimatesDevelopmental Cell2020ISSN 1878-1551
Angé, Marine et al.α1AMP-Activated Protein Kinase Protects against Lipopolysaccharide-Induced Endothelial Barrier Disruption via Junctional Reinforcement and Activation of the p38 MAPK/HSP27 PathwayInternational Journal of Molecular Sciences2020ISSN 1422-0067
Baker, Martin J. et al.P-REX1-independent, calcium-dependent RAC1 hyperactivation in prostate cancerCancers2020ISSN 2072-6694
Chen, Guo Ping et al.Geranylgeranyl Transferase-I Knockout Inhibits Oxidative Injury of Vascular Smooth Muscle Cells and Attenuates Diabetes-Accelerated AtherosclerosisJournal of Diabetes Research2020ISSN 2314-6753
Woida, Patrick J. et al.The Vibrio cholerae MARTX toxin silences the inflammatory response to cytoskeletal damage before inducing actin cytoskeleton collapseScience Signaling2020ISSN 1937-9145
Gokoffski, Kimberly K. et al.Physiologic electrical fields direct retinal ganglion cell axon growth in vitroInvestigative Ophthalmology and Visual Science2019ISSN 1552-5783
Wang, Baomei et al.Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced ColitisCell Reports2019ISSN 2211-1247
Haq, Naila et al.Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neuronsPLoS Biology2019ISSN 1545-7885
Zanin, Juan P. et al.The p75NTR influences cerebellar circuit development and adult behavior via regulation of cell cycle duration of granule cell progenitorsJournal of Neuroscience2019ISSN 1529-2401
Stefanelli, Victoria L. et al.Citrullination of fibronectin alters integrin clustering and focal adhesion stability promoting stromal cell invasionMatrix Biology2019ISSN 1569-1802
Laufer, Julia M. et al.Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac ActivationCell Reports2019ISSN 2211-1247
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Activation of RhoA in Alcohol-Induced Intestinal Barrier Dysfunction | Request PDFArticle Link
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