Cytoskeleton Inc Activation Assay Validation Data and Citations

Activation Assay Citations

AuthorTitleJournalYearArticle Link
Gao, Fei et al.STARD13 is positively correlated with good prognosis and enhances 5-FU sensitivity via suppressing cancer stemness in hepatocellular carcinoma cellsOncoTargets and Therapy2018ISSN 1178-6930
Rafiq, Nisha Bte Mohd et al.Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNOThe Journal of cell biology2017ISSN 1540--8140
Rennoll-Bankert, Kristen E. et al.RalF-Mediated Activation of Arf6 ControlsRickettsia typhiInvasionby Co-Opting Phosphoinositol MetabolismInfect Immun2016PMID 27698019
Schultz, Mark L. et al.CLN3 Deficient Cells Display Defects in the ARF1-Cdc42 Pathway and Actin-Dependent EventsPLOS ONE2014ISSN 1932--6203
AuthorTitleJournalYearArticle Link
Borghesan, Elizabeth et al. A Brucella effector modulates the Arf6‐Rab8a GTPase cascade to promote intravacuolar replication The EMBO Journal2021ISSN 0261--4189
Jackson, Matilda R. et al.Heterozygous loss of function of IQSEC2/Iqsec2 leads to increased activated Arf6 and severe neurocognitive seizure phenotype in femalesLife Science Alliance2019ISSN 2575-1077
Rafiq, Nisha Bte Mohd et al.Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNOThe Journal of cell biology2017ISSN 1540--8140
Stepicheva, Nadezda A. et al.The small GTPase Arf6 regulates sea urchin morphogenesisDifferentiation; research in biological diversity2017ISSN 1432-0436
Biesemann, Anja et al.Rab35 protein regulates evoked exocytosis of endothelial Weibel-Palade bodiesThe Journal of biological chemistry2017ISSN 1083--351X
Rennoll-Bankert, Kristen E. et al.RalF-Mediated Activation of Arf6 ControlsRickettsia typhiInvasionby Co-Opting Phosphoinositol MetabolismInfect Immun2016PMID 27698019
Andrews, Allison M. et al.Mechanical Injury Induces Brain Endothelial-Derived Microvesicle Release: Implications for Cerebral Vascular Injury during Traumatic Brain InjuryFrontiers in Cellular Neuroscience2016ISSN 1662-5102
Marchesin, Valentina et al.ARF6 promotes the formation of Rac1 and WAVE-dependent ventral F-Actin rosettes in breast cancer cells in response to epidermal growth factorPLoS ONE2015ISSN 1932-6203
AuthorTitleJournalYearArticle Link
Salameh, Joëlle et al.Cdc42 and its BORG2 and BORG3 effectors control the subcellular localization of septins between actin stress fibers and microtubulesCurrent Biology2021ISSN 1879-0445
Lee, DanielmiR‑769‑5p is associated with prostate cancer recurrence and modulates proliferation and apoptosis of cancer cellsExperimental and Therapeutic Medicine2021ISSN 1792--0981
Merlin, Johanna et al.Non-canonical glutamine transamination sustains efferocytosis by coupling redox buffering to oxidative phosphorylationNature Metabolism2021ISSN 2522-5812
Wurzer, Hannah et al.Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome In Vitro by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton RemodelingFrontiers in Immunology2021ISSN 1664-3224
Ma, Yuanyuan et al.Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during tooth root developmentDevelopment (Cambridge)2021ISSN 1477-9129
Vallejo, Daniela et al.Wnt5a modulates dendritic spine dynamics through the regulation of Cofilin via small Rho GTPase activity in hippocampal neuronsJournal of Neurochemistry2021ISSN 1471-4159
Jozic, Ivan et al.Glucocorticoid-mediated induction of caveolin-1 disrupts cytoskeletal organization, inhibits cell migration and re-epithelialization of non-healing woundsCommunications Biology2021ISSN 2399-3642
Gorisse, Laetitia et al.Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42Journal of Biological Chemistry2020ISSN 1083-351X
Andrews, Madeline G. et al.Mtor signaling regulates the morphology and migration of outer radial glia in developing human cortexeLife2020ISSN 2050-084X
Zhang, Xiao et al.Elevating EGFR-MAPK program by a nonconventional Cdc42 enhances intestinal epithelial survival and regenerationJCI Insight2020ISSN 2379-3708
Wu, Huijuan et al.Progressive Pulmonary Fibrosis Is Caused by Elevated Mechanical Tension on Alveolar Stem CellsCell2020ISSN 1097-4172
Novak, Caymen M. et al.Compressive stimulation enhances ovarian cancer proliferation, invasion, chemoresistance, and mechanotransduction via cdc42 in a 3d bioreactorCancers2020ISSN 2072-6694
Ursino, Gloria M et al.ABCA12 regulates insulin secretion from β‐cellsEMBO reports2020ISSN 1469--221X
Reyes-Miguel, Tania et al.CDC42 drives RHOA activity and actin polymerization during capacitationReproduction2020ISSN 1741-7899
Wilson, Kitchener D. et al.Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human PrimatesDevelopmental Cell2020ISSN 1878-1551
Choraghe, Rohan P. et al.RHOA-mediated mechanical force generation through Dectin-1Journal of cell science2020ISSN 1477-9137
Malek, Natalia et al.Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) technique shows that non-muscle β and γ actin are not equal in relation to human melanoma cells’ motility and focal adhesion formationInternational Journal of Molecular Sciences2020ISSN 1422-0067
Talamás-Lara, Daniel et al.Entamoeba histolytica and Entamoeba dispar: Morphological and Behavioral Differences Induced by Fibronectin through GTPases Activation and Actin-Binding ProteinsThe Journal of eukaryotic microbiology2020ISSN 1550--7408
Krueger, Irena et al.Reelin amplifies glycoprotein VI activation and alphaiib beta3 integrin outside-in signaling via PLC Gamma 2 and Rho GTPasesArteriosclerosis, Thrombosis, and Vascular Biology2020ISSN 1524-4636
Rong, Zhouyi et al.Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aβ42 in triggering receptor expressed on myeloid cells 2 loss-of-function murine modelsFASEB Journal2020ISSN 1530-6860
Wu, Xuping et al.Wnt5a induces ROR1 and ROR2 to activate RhoA in esophageal squamous cell carcinoma cellsCancer Management and Research2019ISSN 1179-1322
Zanin, Juan P. et al.The p75NTR influences cerebellar circuit development and adult behavior via regulation of cell cycle duration of granule cell progenitorsJournal of Neuroscience2019ISSN 1529-2401
Yan, Ting et al.Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cellsJournal of Biological Chemistry2018ISSN 1083-351X
Mayer, Louisa et al.Nbeal2 interacts with Dock7, Sec16a, and Vac14Blood2018ISSN 1528-0020
Suraneni, Praveen K. et al.Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activityBlood Advances2018ISSN 2473-9537
Santhana Kumar, Karthiga et al.TGF-β Determines the Pro-migratory Potential of bFGF Signaling in MedulloblastomaCell Reports2018ISSN 2211-1247
Veluthakal, Rajakrishnan et al.Restoration of glucose-stimulated Cdc42-PAK1 activation and insulin secretion by a selective Epac activator in type 2 diabetic human isletsDiabetes2018ISSN 1939-327X
Ruggiero, Carmen et al.Dosage-dependent regulation of VAV2 expression by steroidogenic factor-1 drives adrenocortical carcinoma cell invasionScience Signaling2017ISSN 1937-9145
Kim, Jongshin et al.YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturationJournal of Clinical Investigation2017ISSN 1558-8238
Gu, Changkyu et al.Dynamin autonomously regulates podocyte focal adhesion maturationJournal of the American Society of Nephrology2017ISSN 1533-3450
Jones, Eleanor L. et al.Dendritic Cell Migration and Antigen Presentation Are Coordinated by the Opposing Functions of the Tetraspanins CD82 and CD37The Journal of Immunology2016ISSN 0022--1767
Herrera-Martínez, Mayra et al.Antiamoebic activity of Adenophyllum aurantium (L.) strother and its effect on the actin cytoskeleton of Entamoeba histolyticaFrontiers in Pharmacology2016ISSN 1663-9812
Martins, Rui et al.Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functionsNature Immunology2016ISSN 1529-2916
Zhao, Chen Ze et al.Inhibition of farnesyl pyrophosphate synthase improves pressure overload induced chronic cardiac remodelingScientific Reports2016ISSN 2045-2322
Sroka, Jolanta et al.Lamellipodia and membrane blebs drive efficient electrotactic migration of rat walker carcinosarcoma cells WC 256PLoS ONE2016ISSN 1932-6203
Xiao, Bin et al.Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signalingOncotarget2016ISSN 1949-2553
Tien, Sui Chih et al.The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42Nature Communications2016ISSN 2041-1723
Breslin, Jerome W. et al.Involvement of local lamellipodia in endothelial barrier functionPLoS ONE2015ISSN 1932-6203
Yan, Yi et al.Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5Nature Communications2015ISSN 2041-1723
Guo, Yuna et al.A novel pharmacologic activity of ketorolac for therapeutic benefit in ovarian cancer patientsClinical Cancer Research2015ISSN 1557-3265
Ochoa-Alvarez, Jhon A. et al.Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanismsOncotarget2015ISSN 1949-2553
Ahn, Bum Ju et al.Ninjurin1 enhances the basal motility and transendothelial migration of immune cells by inducing protrusive membrane dynamicsJournal of Biological Chemistry2014ISSN 1083-351X
Hanin, Geula et al.Competing targets of microRNA-608 affect anxiety and hypertensionHuman Molecular Genetics2014ISSN 1460-2083
Chakravarti, Bandana et al.Thioaryl naphthylmethanone oxime ether analogs as novel anticancer agentsJournal of Medicinal Chemistry2014ISSN 1520-4804
Rigano, Luciano A. et al.Listeria monocytogenes antagonizes the human GTPase Cdc42 to promote bacterial spreadCellular Microbiology2014ISSN 1462-5822
Valtcheva, Nadejda et al.The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42Journal of Biological Chemistry2013ISSN 0021-9258
Barrio, Laura et al.TLR4 Signaling Shapes B Cell Dynamics via MyD88-Dependent Pathways and Rac GTPasesThe Journal of Immunology2013ISSN 0022--1767
Yao, Honghong et al.Nonmuscle myosin light-chain kinase mediates microglial migration induced by HIV Tat: involvement of β1 integrinsFASEB journal : official publication of the Federation of American Societies for Experimental Biology2013ISSN 1530--6860
Kalia, Manjula et al.Japanese Encephalitis Virus Infects Neuronal Cells through a Clathrin-Independent Endocytic MechanismJournal of Virology2013ISSN 0022--538X
Dubash, Adi D. et al.The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1Journal of Cell Biology2013ISSN 0021-9525
Ramsay, Alan G. et al.Chronic lymphocytic leukemia cells induce defective LFA-1-directed T-cell motility by altering Rho GTPase signaling that is reversible with lenalidomideBlood2013ISSN 1528-0020
Bray, Kristi et al.Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migrationBreast Cancer Research2013ISSN 1465-5411
Chen, Bin et al.Alteration of mevalonate pathway related enzyme expressions in pressure overload-induced cardiac hypertrophy and associated heart failure with preserved ejection fractionCellular Physiology and Biochemistry2013ISSN 1421-9778
Yang, Jian et al.Cardiac-specific overexpression of farnesyl pyrophosphate synthase induces cardiac hypertrophy and dysfunction in miceCardiovascular Research2013ISSN 0008-6363
Ramsay, Alan G. et al.Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: Establishing a reversible immune evasion mechanism in human cancerBlood2012ISSN 1528-0020
Elali, Ayman et al.Liver X receptor activation enhances blood-brain barrier integrity in the ischemic brain and increases the abundance of ATP-binding cassette transporters ABCB1 and ABCC1 on brain capillary cellsBrain Pathology2012ISSN 1015-6305
Chen, Si Meng et al.Inhibition of tumor cell growth, proliferation and migration by X-387, a novel active-site inhibitor of mTORBiochemical Pharmacology2012ISSN 0006-2952
Martin-Granados, Cristina et al.A role for PP1/NIPP1 in steering migration of human cancer cellsPLoS ONE2012ISSN 1932-6203
Eggers, Carrie M. et al.STE20-related kinase adaptor protein α (STRADα) regulates cell polarity and invasion through PAK1 signaling in LKB1-null cellsThe Journal of biological chemistry2012ISSN 1083--351X
Dhaliwal, Anandika et al.Cellular Cytoskeleton Dynamics Modulates Non-Viral Gene Delivery through RhoGTPases2012PMID 22509380
Chen, Guang et al.Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells (Journal of Biological Chemistry (2012) 2Journal of Biological Chemistry2012ISSN 0021-9258
McHenry, Peter R. et al.P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasisBreast Cancer Research2010ISSN 1465-5411
Lichtenstein, Mathieu P. et al.Secretase-independent and RhoGTPase/PAK/ERK-dependent regulation of cytoskeleton dynamics in astrocytes by NSAIDs and derivativesJournal of Alzheimer's disease : JAD2010ISSN 1875--8908
Romero, Ana M. et al.Chronic ethanol exposure alters the levels, assembly, and cellular organization of the actin cytoskeleton and microtubules in hippocampal neurons in primary cultureToxicological Sciences2010ISSN 1096-6080
Stankiewicz, Traci E. et al.GTPase activating protein function of p85 facilitates uptake and recycling of the β1 integrinBiochemical and biophysical research communications2010ISSN 0006-291X
Schlegel, Nicolas et al.Impaired cAMP and Rac 1 signaling contribute to TNF-alpha-induced endothelial barrier breakdown in microvascular endotheliumMicrocirculation (New York, N.Y. : 1994)2009ISSN 1549--8719
Heckman-Stoddard, Brandy M. et al.Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression2009ISSN 1465-5411
AuthorTitleJournalYearArticle Link
Nath, Anu S. et al.Modulation of the cell membrane lipid milieu by peroxisomal β-oxidation induces Rho1 signaling to trigger inflammatory responsesCell Reports2022ISSN 2211-1247
Turgu, Busra et al.HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent mannerOncogene2021ISSN 1476-5594
Garitano-Trojaola, Andoni et al.Actin cytoskeleton deregulation confers midostaurin resistance in FLT3-mutant acute myeloid leukemiaCommunications biology2021ISSN 2399-3642
Crawford, Melissa et al.Essential Role for Integrin-Linked Kinase in Melanoblast Colonization of the SkinJournal of Investigative Dermatology2020ISSN 1523-1747
Berthenet, Kevin et al.Failed Apoptosis Enhances Melanoma Cancer Cell AggressivenessCell Reports2020ISSN 2211-1247
Zhu, Bili et al.Lipid oversupply induces CD36 sarcolemmal translocation via dual modulation of PKCζ and TBC1D1: An early event prior to insulin resistanceTheranostics2020ISSN 1838-7640
Elshaer, Sally L. et al.Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinal vascular permeability in mice via inhibition of inflammation and the RhoA kinase pathwayDiabetologia2019ISSN 1432-0428
El-Naggar, Amal M. et al.HACE1 is a potential tumor suppressor in osteosarcomaCell Death and Disease2019ISSN 2041-4889
Kang, Jeong Hun et al.Protein kinase Cα as a therapeutic target in cancerProtein Kinase C: Emerging Roles and Therapeutic Potential2018Article Link
Yan, Ting et al.Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cellsJournal of Biological Chemistry2018ISSN 1083-351X
Ruggiero, Carmen et al.Dosage-dependent regulation of VAV2 expression by steroidogenic factor-1 drives adrenocortical carcinoma cell invasionScience Signaling2017ISSN 1937-9145
Jeong, Suk Yeong et al.Loss of Tpm4.1 leads to disruption of cell-cell adhesions and invasive behavior in breast epithelial cells via increased Rac1 signalingOncotarget2017ISSN 1949-2553
Kim, Jongshin et al.YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturationJournal of Clinical Investigation2017ISSN 1558-8238
Kai, Masahiro et al.Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancerMolecular Carcinogenesis2017ISSN 1098-2744
Sylow, Lykke et al.Rac1 governs exercise-stimulated glucose uptake in skeletal muscle through regulation of GLUT4 translocation in miceJournal of Physiology2016ISSN 1469-7793
Thuault, Sylvie et al.The RhoE/ROCK/ARHGAP25 signaling pathway controls cell invasion by inhibition of Rac activityMolecular Biology of the Cell2016ISSN 1939-4586
Sarowar, Tasnuva et al.Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2Molecular Brain2016ISSN 1756-6606
Reyes-Reyes, E. Merit et al.Mechanistic studies of anticancer aptamer AS1411 reveal a novel role for nucleolin in regulating Rac1 activationMolecular Oncology2015ISSN 1878-0261
Yan, Yi et al.Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5Nature Communications2015ISSN 2041-1723
Marchesin, Valentina et al.ARF6 promotes the formation of Rac1 and WAVE-dependent ventral F-Actin rosettes in breast cancer cells in response to epidermal growth factorPLoS ONE2015ISSN 1932-6203
Radeva, Mariya Y. et al.PKA compartmentalization via AKAP220 and AKAP12 contributes to endothelial barrier regulationPLoS ONE2014ISSN 1932-6203
Nakajima, Chikako et al.The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular developmentDevelopment (Cambridge)2014ISSN 1477-9129
Sylow, Lykke et al.Rac1 - a novel regulator of contraction-stimulated glucose uptake in skeletal muscleExperimental Physiology2014ISSN 1469-445X
Redhu, Naresh Singh et al.Thymic stromal lymphopoietin induces migration in human airway smooth muscle cellsScientific Reports2013ISSN 2045-2322
Sylow, Lykke et al.Rac1 signaling is required for insulin-stimulated glucose uptake and is dysregulated in insulin-resistant murine and human skeletal muscleDiabetes2013ISSN 0012-1797
Kikuchi, K. et al.Protein kinase C iota as a therapeutic target in alveolar rhabdomyosarcomaOncogene2013ISSN 1476--5594
Bray, Kristi et al.Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migrationBreast Cancer Research2013ISSN 1465-5411
Eggers, Carrie M. et al.STE20-related kinase adaptor protein α (STRADα) regulates cell polarity and invasion through PAK1 signaling in LKB1-null cellsThe Journal of biological chemistry2012ISSN 1083--351X
Sayedyahossein, Samar et al.Essential role of integrin-linked kinase in regulation of phagocytosis in keratinocytesFASEB Journal2012ISSN 1530-6860
Binker, Marcelo G. et al.TGF-β1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-κB/IL-6/MMP-2Biochemical and biophysical research communications2011ISSN 1090--2104
Kigel, Boaz et al.Plexin-A4 promotes tumor progression and tumor angiogenesis by enhancement of VEGF and bFGF signalingBlood2011ISSN 1528-0020
Vives, Virginie et al.The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts2011ISSN 1523--4681
Johanna, Gutiérrez Vargas et al.Rac1 activity changes are associated with neuronal pathology and spatial memory long-term recovery after global cerebral ischemiaNeurochemistry international2010ISSN 1872--9754
Kamai, Takao et al.Increased Rac1 activity and Pak1 overexpression are associated with lymphovascular invasion and lymph node metastasis of upper urinary tract cancerBMC Cancer2010ISSN 1471-2407
McHenry, Peter R. et al.P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasisBreast Cancer Research2010ISSN 1465-5411
Chastre, Eric et al.TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasivenessThe FASEB Journal2009ISSN 1530--6860
Heckman-Stoddard, Brandy M. et al.Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression2009ISSN 1465-5411
Baumer, Y. et al.Role of Rac 1 and cAMP in endothelial barrier stabilization and thrombin-induced barrier breakdownJournal of Cellular Physiology2009ISSN 1097--4652
Moniz, Sónia et al.WNK2 modulates MEK1 activity through the Rho GTPase pathwayCellular signalling2008ISSN 0898--6568
Petroll, W. Matthew et al.Dynamic assessment of fibroblast mechanical activity during rac-induced cell spreading in 3-D cultureJournal of Cellular Physiology2008ISSN 0021-9541
Ramirez, Servio H. et al.Activation of Peroxisome Proliferator-Activated Receptor γ (PPARγ) Suppresses Rho GTPases in Human Brain Microvascular Endothelial Cells and Inhibits Adhesion and Transendothelial Migration of HIV-1 Infected MonocytesThe Journal of Immunology2008ISSN 0022--1767
Pontow, Suzanne et al.Antiviral Activity of a Rac GEF inhibitor Characterized with a Sensitive HIV/SIV Fusion AssayVirology2007ISSN 0042-6822
AuthorTitleJournalYearArticle Link
Kim, Seunghoon et al.Investigating the Anti-Inflammatory Effects of RCI001 for Treating Ocular Surface Diseases: Insight Into the Mechanism of ActionFrontiers in Immunology2022ISSN 1664-3224
Borza, Corina M. et al.The Collagen Receptor Discoidin Domain Receptor 1b Enhances Integrin β1-Mediated Cell Migration by Interacting With Talin and Promoting Rac1 ActivationFrontiers in Cell and Developmental Biology2022Article Link
Sugisawa, Erika et al.Nociceptor-derived Reg3γ prevents endotoxic death by targeting kynurenine pathway in microgliaCell Reports2022ISSN 2211-1247
Wegscheid, Michelle L. et al.Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesisCell Reports2021ISSN 2211-1247
Mao, De Yu et al.CLIC1 and CLIC4 mediate endothelial S1P receptor signaling to facilitate Rac1 and RhoA activity and functionScience Signaling2021ISSN 1937-9145
Kinsella, Sinéad et al.Attenuation of apoptotic cell detection triggers thymic regeneration after damageCell Reports2021ISSN 2211-1247
Ma, Shang et al.A role of PIEZO1 in iron metabolism in mice and humansCell2021ISSN 1097-4172
Gurusamy, Malarvizhi et al.G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediatorsNature Communications2021ISSN 2041-1723
Vallejo, Daniela et al.Wnt5a modulates dendritic spine dynamics through the regulation of Cofilin via small Rho GTPase activity in hippocampal neuronsJournal of Neurochemistry2021ISSN 1471-4159
Merlin, Johanna et al.Non-canonical glutamine transamination sustains efferocytosis by coupling redox buffering to oxidative phosphorylationNature Metabolism2021ISSN 2522-5812
Ma, Yuanyuan et al.Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during tooth root developmentDevelopment (Cambridge)2021ISSN 1477-9129
Choraghe, Rohan P. et al.RHOA-mediated mechanical force generation through Dectin-1Journal of cell science2020ISSN 1477-9137
Szrejder, Maria et al.Metformin reduces TRPC6 expression through AMPK activation and modulates cytoskeleton dynamics in podocytes under diabetic conditionsBiochimica et Biophysica Acta - Molecular Basis of Disease2020ISSN 1879-260X
Sheftel, Celeste M. et al.Serotonin stimulated parathyroid hormone related protein induction in the mammary epithelia by transglutaminase-dependent serotonylationPLoS ONE2020ISSN 1932-6203
Andrews, Madeline G. et al.Mtor signaling regulates the morphology and migration of outer radial glia in developing human cortexeLife2020ISSN 2050-084X
Wilson, Kitchener D. et al.Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human PrimatesDevelopmental Cell2020ISSN 1878-1551
Kowluru, Renu A.Retinopathy in a diet-induced type 2 diabetic rat model and role of epigenetic modificationsDiabetes2020ISSN 1939-327X
Larribère, Lionel et al.NF1-RAC1 axis regulates migration of the melanocytic lineageTranslational Oncology2020ISSN 1936-5233
Rong, Zhouyi et al.Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aβ42 in triggering receptor expressed on myeloid cells 2 loss-of-function murine modelsFASEB Journal2020ISSN 1530-6860
Angé, Marine et al.α1AMP-Activated Protein Kinase Protects against Lipopolysaccharide-Induced Endothelial Barrier Disruption via Junctional Reinforcement and Activation of the p38 MAPK/HSP27 PathwayInternational Journal of Molecular Sciences2020ISSN 1422-0067
Malek, Natalia et al.Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) technique shows that non-muscle β and γ actin are not equal in relation to human melanoma cells’ motility and focal adhesion formationInternational Journal of Molecular Sciences2020ISSN 1422-0067
Krueger, Irena et al.Reelin amplifies glycoprotein VI activation and alphaiib beta3 integrin outside-in signaling via PLC Gamma 2 and Rho GTPasesArteriosclerosis, Thrombosis, and Vascular Biology2020ISSN 1524-4636
Woida, Patrick J. et al.The Vibrio cholerae MARTX toxin silences the inflammatory response to cytoskeletal damage before inducing actin cytoskeleton collapseScience Signaling2020ISSN 1937-9145
Chen, Guo Ping et al.Geranylgeranyl Transferase-I Knockout Inhibits Oxidative Injury of Vascular Smooth Muscle Cells and Attenuates Diabetes-Accelerated AtherosclerosisJournal of Diabetes Research2020ISSN 2314-6753
Baker, Martin J. et al.P-REX1-independent, calcium-dependent RAC1 hyperactivation in prostate cancerCancers2020ISSN 2072-6694
Stefanelli, Victoria L. et al.Citrullination of fibronectin alters integrin clustering and focal adhesion stability promoting stromal cell invasionMatrix Biology2019ISSN 1569-1802
Zanin, Juan P. et al.The p75NTR influences cerebellar circuit development and adult behavior via regulation of cell cycle duration of granule cell progenitorsJournal of Neuroscience2019ISSN 1529-2401
Haq, Naila et al.Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neuronsPLoS Biology2019ISSN 1545-7885
Wu, Wenjuan et al.Inhibition of Rac1-dependent forgetting alleviates memory deficits in animal models of Alzheimer’s diseaseProtein and Cell2019ISSN 1674-8018
Gokoffski, Kimberly K. et al.Physiologic electrical fields direct retinal ganglion cell axon growth in vitroInvestigative Ophthalmology and Visual Science2019ISSN 1552-5783
Soni, Upendra Kumar et al.A high level of TGF-B1 promotes endometriosis development via cell migration, adhesiveness, colonization, and invasivenessBiology of Reproduction2019ISSN 1529-7268
Wang, Baomei et al.Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced ColitisCell Reports2019ISSN 2211-1247
De Bessa, Tiphany Coralie et al.Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRasCell Death and Disease2019ISSN 2041-4889
Laufer, Julia M. et al.Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac ActivationCell Reports2019ISSN 2211-1247
Shi, Wei et al.EPHB6 controls catecholamine biosynthesis by up-regulating tyrosine hydroxylase transcription in adrenal gland chromaffin cellsJournal of Biological Chemistry2019ISSN 1083-351X
Saito-Reis, Chelsea A. et al.The tetraspanin CD82 regulates bone marrow homing and engraftment of hematopoietic stem and progenitor cellsMolecular Biology of the Cell2018ISSN 1939-4586
Duraisamy, Arul J. et al.Epigenetics and regulation of oxidative stress in diabetic retinopathyInvestigative Ophthalmology and Visual Science2018ISSN 1552-5783
Stierwalt, Harrison D. et al.Insulin-stimulated Rac1-GTP binding is not impaired by palmitate treatment in L6 myotubesPhysiological Reports2018ISSN 2051-817X
Proto, Jonathan D. et al.Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation ResolutionImmunity2018ISSN 1097-4180
Rachubik, Patrycja et al.The TRPC6-AMPK pathway is involved in insulin-dependent cytoskeleton reorganization and glucose uptake in cultured rat podocytesCellular Physiology and Biochemistry2018ISSN 1421-9778
Olabi, Safiah et al.Integrin-Rac signalling for mammary epithelial stem cell self-renewal 06 Biological Sciences 0601 Biochemistry and Cell BiologyBreast Cancer Research2018ISSN 1465-542X
Mayer, Louisa et al.Nbeal2 interacts with Dock7, Sec16a, and Vac14Blood2018ISSN 1528-0020
Suraneni, Praveen K. et al.Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activityBlood Advances2018ISSN 2473-9537
Peretti, Amanda S. et al.The R-Enantiomer of Ketorolac Delays Mammary Tumor Development in Mouse Mammary Tumor Virus-Polyoma Middle T Antigen (MMTV-PyMT) MiceAmerican Journal of Pathology2018ISSN 1525-2191
Santhana Kumar, Karthiga et al.TGF-β Determines the Pro-migratory Potential of bFGF Signaling in MedulloblastomaCell Reports2018ISSN 2211-1247
Caggia, Silvia et al.Novel role of Giα2 in cell migration: Downstream of PI3-kinase–AKT and Rac1 in prostate cancer cellsJournal of Cellular Physiology2018ISSN 1097-4652
Dyberg, Cecilia et al.Rho-associated kinase is a therapeutic target in neuroblastomaProceedings of the National Academy of Sciences of the United States of America2017ISSN 1091-6490
Hendricks, Louie et al.Milk fat globule-epidermal growth factor-factor VIII–derived peptide MSP68 is a cytoskeletal immunomodulator of neutrophils that inhibits Rac1Journal of Surgical Research2017ISSN 1095-8673
Moreno-Layseca, Paulina et al.The requirement of integrins for breast epithelial proliferationEuropean Journal of Cell Biology2017ISSN 1618-1298
Kumar, Vijay et al.Integrin beta8 (ITGB8) activates VAV-RAC1 signaling via FAK in the acquisition of endometrial epithelial cell receptivity for blastocyst implantationScientific Reports2017ISSN 2045-2322
Ubba, Vaibhave et al.RHOG-DOCK1-RAC1 Signaling Axis Is Perturbed in DHEA-Induced Polycystic Ovary in Rat ModelReproductive Sciences2017ISSN 1933-7205
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Birkl, Dorothee et al.TNFα promotes mucosal wound repair through enhanced platelet activating factor receptor signaling in the epitheliumMucosal Immunology2019ISSN 1935-3456
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Cheng, Lili et al.Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicityArchives of Toxicology2018ISSN 1432-0738
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Nishiyama, Kanako et al.CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTPLife Science Alliance2021ISSN 2575-1077
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Liang, Liang et al.The long noncoding RNA HOTAIRM1 controlled by AML1 enhances glucocorticoid resistance by activating RHOA/ROCK1 pathway through suppressing ARHGAP18Cell Death and Disease2021ISSN 2041-4889
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Activation of RhoA in Alcohol-Induced Intestinal Barrier Dysfunction | Request PDFArticle Link
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