Author | Title | Journal | Year | Article Link |
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Ji, Juanjuan et al. | TMEM16A enhances the activity of the Cdc42-NWASP signaling pathway to promote invasion and metastasis in oral squamous cell carcinoma | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology | 2024 | |
Szigeti, Kinga et al. | CHRFAM7A diversifies human immune adaption through Ca2+ signalling and actin cytoskeleton reorganization | eBioMedicine | 2024 | |
Mendoza-Soto, Pablo et al. | Pharmacological Blockade of the Adenosine A2B Receptor Is Protective of Proteinuria in Diabetic Rats, through Affecting Focal Adhesion Kinase Activation and the Adhesion Dynamics of Podocytes | Cells | 2024 | |
Wu, Fei et al. | Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight | Nature Communications | 2024 | |
Lee, Choong Jae et al. | The dysadherin/FAK axis promotes individual cell migration in colon cancer | International Journal of Biological Sciences | 2024 | |
Liang, Bishan et al. | Cdc42-driven endosomal cholesterol transport promotes collateral resistance in HER2-positive gastric cancer | Cancer Letters | 2024 | |
Adhicary, Subhodip et al. | Rbpj Deficiency Disrupts Vascular Remodeling via Abnormal Apelin and Cdc42 (Cell Division Cycle 42) Activity in Brain Arteriovenous Malformation | Stroke | 2023 | |
Szigeti, Kinga et al. | Neuronal actin cytoskeleton gain of function in the human brain | eBioMedicine | 2023 | |
Xie, Wangkai et al. | ASAP1 activates the IQGAP1/CDC42 pathway to promote tumor progression and chemotherapy resistance in gastric cancer | Cell Death & Disease | 2023 | |
Punessen, Noelle C. et al. | A novel anti-apoptotic role for Cdc42/ACK-1 signaling in neurons | Molecular and Cellular Neuroscience | 2023 | |
St. Paul, Amanda et al. | FXR1 regulates vascular smooth muscle cell cytoskeleton, VSMC contractility, and blood pressure by multiple mechanisms | Cell reports | 2023 | |
Castillo-Azofeifa, David et al. | A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signaling | Cell stem cell | 2023 | |
Crespo, Grace Velez et al. | The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancer | Molecular Medicine | 2023 | |
Adhicary, Subhodip et al. | Rbpj Deficiency Disrupts Vascular Remodeling via Abnormal Apelin and Cdc42 (Cell Division Cycle 42) Activity in Brain Arteriovenous Malformation | Stroke | 2023 | |
Zi, Jingjing et al. | PFN1 Inhibits Myogenesis of Bovine Myoblast Cells via Cdc42-PAK/JNK | Cells | 2022 | |
Meng, Zhipeng et al. | The Hippo pathway mediates Semaphorin signaling | Science Advances | 2022 | |
Jiang, Ruiwei et al. | CDC42 governs normal oviduct multiciliogenesis through activating AKT to ensure timely embryo transport | Cell Death & Disease | 2022 | |
Ma, Yuanyuan et al. | Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during tooth root development | Development (Cambridge) | 2021 | |
Jozic, Ivan et al. | Glucocorticoid-mediated induction of caveolin-1 disrupts cytoskeletal organization, inhibits cell migration and re-epithelialization of non-healing wounds | Communications Biology | 2021 | |
Vallejo, Daniela et al. | Wnt5a modulates dendritic spine dynamics through the regulation of Cofilin via small Rho GTPase activity in hippocampal neurons | Journal of Neurochemistry | 2021 | |
Wurzer, Hannah et al. | Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome In Vitro by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton Remodeling | Frontiers in Immunology | 2021 | |
Merlin, Johanna et al. | Non-canonical glutamine transamination sustains efferocytosis by coupling redox buffering to oxidative phosphorylation | Nature Metabolism | 2021 | |
Lee, Daniel | miR‑769‑5p is associated with prostate cancer recurrence and modulates proliferation and apoptosis of cancer cells | Experimental and Therapeutic Medicine | 2021 | |
Salameh, Joëlle et al. | Cdc42 and its BORG2 and BORG3 effectors control the subcellular localization of septins between actin stress fibers and microtubules | Current Biology | 2021 | |
Talamás-Lara, Daniel et al. | Entamoeba histolytica and Entamoeba dispar: Morphological and Behavioral Differences Induced by Fibronectin through GTPases Activation and Actin-Binding Proteins | The Journal of eukaryotic microbiology | 2020 | |
Krueger, Irena et al. | Reelin amplifies glycoprotein VI activation and alphaiib beta3 integrin outside-in signaling via PLC Gamma 2 and Rho GTPases | Arteriosclerosis, Thrombosis, and Vascular Biology | 2020 | |
Rong, Zhouyi et al. | Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aβ42 in triggering receptor expressed on myeloid cells 2 loss-of-function murine models | FASEB Journal | 2020 | |
Andrews, Madeline G. et al. | Mtor signaling regulates the morphology and migration of outer radial glia in developing human cortex | eLife | 2020 | |
Choraghe, Rohan P. et al. | RHOA-mediated mechanical force generation through Dectin-1 | Journal of cell science | 2020 | |
Malek, Natalia et al. | Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) technique shows that non-muscle β and γ actin are not equal in relation to human melanoma cells’ motility and focal adhesion formation | International Journal of Molecular Sciences | 2020 | |
Wilson, Kitchener D. et al. | Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates | Developmental Cell | 2020 | |
Reyes-Miguel, Tania et al. | CDC42 drives RHOA activity and actin polymerization during capacitation | Reproduction | 2020 | |
Ursino, Gloria M et al. | ABCA12 regulates insulin secretion from β‐cells | EMBO reports | 2020 | |
Novak, Caymen M. et al. | Compressive stimulation enhances ovarian cancer proliferation, invasion, chemoresistance, and mechanotransduction via cdc42 in a 3d bioreactor | Cancers | 2020 | |
Wu, Huijuan et al. | Progressive Pulmonary Fibrosis Is Caused by Elevated Mechanical Tension on Alveolar Stem Cells | Cell | 2020 | |
Zhang, Xiao et al. | Elevating EGFR-MAPK program by a nonconventional Cdc42 enhances intestinal epithelial survival and regeneration | JCI Insight | 2020 | |
Gorisse, Laetitia et al. | Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42 | Journal of Biological Chemistry | 2020 | |
Zanin, Juan P. et al. | The p75NTR influences cerebellar circuit development and adult behavior via regulation of cell cycle duration of granule cell progenitors | Journal of Neuroscience | 2019 | |
Wu, Xuping et al. | Wnt5a induces ROR1 and ROR2 to activate RhoA in esophageal squamous cell carcinoma cells | Cancer Management and Research | 2019 | |
Santhana Kumar, Karthiga et al. | TGF-β Determines the Pro-migratory Potential of bFGF Signaling in Medulloblastoma | Cell Reports | 2018 | |
Yan, Ting et al. | Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells | Journal of Biological Chemistry | 2018 | |
Suraneni, Praveen K. et al. | Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activity | Blood Advances | 2018 | |
Mayer, Louisa et al. | Nbeal2 interacts with Dock7, Sec16a, and Vac14 | Blood | 2018 | |
Veluthakal, Rajakrishnan et al. | Restoration of glucose-stimulated Cdc42-PAK1 activation and insulin secretion by a selective Epac activator in type 2 diabetic human islets | Diabetes | 2018 | |
Gu, Changkyu et al. | Dynamin autonomously regulates podocyte focal adhesion maturation | Journal of the American Society of Nephrology | 2017 | |
Ruggiero, Carmen et al. | Dosage-dependent regulation of VAV2 expression by steroidogenic factor-1 drives adrenocortical carcinoma cell invasion | Science Signaling | 2017 | |
Kim, Jongshin et al. | YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation | Journal of Clinical Investigation | 2017 | |
Xiao, Bin et al. | Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling | Oncotarget | 2016 | |
Jones, Eleanor L. et al. | Dendritic Cell Migration and Antigen Presentation Are Coordinated by the Opposing Functions of the Tetraspanins CD82 and CD37 | The Journal of Immunology | 2016 | |
Sroka, Jolanta et al. | Lamellipodia and membrane blebs drive efficient electrotactic migration of rat walker carcinosarcoma cells WC 256 | PLoS ONE | 2016 | |
Zhao, Chen Ze et al. | Inhibition of farnesyl pyrophosphate synthase improves pressure overload induced chronic cardiac remodeling | Scientific Reports | 2016 | |
Tien, Sui Chih et al. | The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42 | Nature Communications | 2016 | |
Martins, Rui et al. | Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions | Nature Immunology | 2016 | |
Herrera-Martínez, Mayra et al. | Antiamoebic activity of Adenophyllum aurantium (L.) strother and its effect on the actin cytoskeleton of Entamoeba histolytica | Frontiers in Pharmacology | 2016 | |
Ochoa-Alvarez, Jhon A. et al. | Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanisms | Oncotarget | 2015 | |
Guo, Yuna et al. | A novel pharmacologic activity of keto***** for therapeutic benefit in ovarian cancer patients | Clinical Cancer Research | 2015 | |
Breslin, Jerome W. et al. | Involvement of local lamellipodia in endothelial barrier function | PLoS ONE | 2015 | |
Yan, Yi et al. | Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5 | Nature Communications | 2015 | |
Hanin, Geula et al. | Competing targets of microRNA-608 affect anxiety and hypertension | Human Molecular Genetics | 2014 | |
Ahn, Bum Ju et al. | Ninjurin1 enhances the basal motility and transendothelial migration of immune cells by inducing protrusive membrane dynamics | Journal of Biological Chemistry | 2014 | |
Rigano, Luciano A. et al. | Listeria monocytogenes antagonizes the human GTPase Cdc42 to promote bacterial spread | Cellular Microbiology | 2014 | |
Chakravarti, Bandana et al. | Thioaryl naphthylmethanone oxime ether analogs as novel anticancer agents | Journal of Medicinal Chemistry | 2014 | |
Kalia, Manjula et al. | Japanese Encephalitis Virus Infects Neuronal Cells through a Clathrin-Independent Endocytic Mechanism | Journal of Virology | 2013 | |
Yao, Honghong et al. | Nonmuscle myosin light-chain kinase mediates microglial migration induced by HIV Tat: involvement of β1 integrins | FASEB journal | 2013 | |
Dubash, Adi D. et al. | The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1 | Journal of Cell Biology | 2013 | |
Ramsay, Alan G. et al. | Chronic lymphocytic leukemia cells induce defective LFA-1-directed T-cell motility by altering Rho GTPase signaling that is reversible with lenali****** | Blood | 2013 | |
Bray, Kristi et al. | Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration | Breast Cancer Research | 2013 | |
Chen, Bin et al. | Alteration of mevalonate pathway related enzyme expressions in pressure overload-induced cardiac hypertrophy and associated heart failure with preserved ejection fraction | Cellular Physiology and Biochemistry | 2013 | |
Yang, Jian et al. | Cardiac-specific overexpression of farnesyl pyrophosphate synthase induces cardiac hypertrophy and dysfunction in mice | Cardiovascular Research | 2013 | |
Valtcheva, Nadejda et al. | The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42 | Journal of Biological Chemistry | 2013 | |
Barrio, Laura et al. | TLR4 Signaling Shapes B Cell Dynamics via MyD88-Dependent Pathways and Rac GTPases | The Journal of Immunology | 2013 | |
Chen, Guang et al. | Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells (Journal of Biological Chemistry (2012) 2 | Journal of Biological Chemistry | 2012 | |
Dhaliwal, Anandika et al. | Cellular Cytoskeleton Dynamics Modulates Non-Viral Gene Delivery through RhoGTPases | PLoS ONE | 2012 | |
Eggers, Carrie M. et al. | STE20-related kinase adaptor protein α (STRADα) regulates cell polarity and invasion through PAK1 signaling in LKB1-null cells | The Journal of biological chemistry | 2012 | |
Ramsay, Alan G. et al. | Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenali******: Establishing a reversible immune evasion mechanism in human cancer | Blood | 2012 | |
Chen, Si Meng et al. | Inhibition of tumor cell growth, proliferation and migration by X-387, a novel active-site inhibitor of mTOR | Biochemical Pharmacology | 2012 | |
Elali, Ayman et al. | Liver X receptor activation enhances blood-brain barrier integrity in the ischemic brain and increases the abundance of ATP-binding cassette transporters ABCB1 and ABCC1 on brain capillary cells | Brain Pathology | 2012 | |
Martin-Granados, Cristina et al. | A role for PP1/NIPP1 in steering migration of human cancer cells | PLoS ONE | 2012 | |
Lichtenstein, Mathieu P. et al. | Secretase-independent and RhoGTPase/PAK/ERK-dependent regulation of cytoskeleton dynamics in astrocytes by NSAIDs and derivatives | Journal of Alzheimer's disease : JAD | 2010 | |
McHenry, Peter R. et al. | P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis | Breast Cancer Research | 2010 | |
Romero, Ana M. et al. | Chronic ethanol exposure alters the levels, assembly, and cellular organization of the actin cytoskeleton and microtubules in hippocampal neurons in primary culture | Toxicological Sciences | 2010 | |
Stankiewicz, Traci E. et al. | GTPase activating protein function of p85 facilitates uptake and recycling of the β1 integrin | Biochemical and biophysical research communications | 2010 | |
Heckman-Stoddard, Brandy M. et al. | Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression | | 2009 | |
Schlegel, Nicolas et al. | Impaired cAMP and Rac 1 signaling contribute to TNF-alpha-induced endothelial barrier breakdown in microvascular endothelium | Microcirculation (New York, N.Y. : 1994) | 2009 | |