Author | Title | Journal | Year | Article Link |
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Li, Fuxiang et al. | SIRT7 remodels the cytoskeleton via RAC1 to enhance host resistance to Mycobacterium tuberculosis | mBio | 2024 | |
Martin, Lee J. et al. | Nuclear Localization of Human SOD1 in Motor Neurons in Mouse Model and Patient Amyotrophic Lateral Sclerosis: Possible Links to Cholinergic Phenotype, NADPH Oxidase, Oxidative Stress, and DNA Damage | International Journal of Molecular Sciences | 2024 | |
Voglewede, Mikayla M. et al. | Loss of the polarity protein Par3 promotes dendritic spine neoteny and enhances learning and memory | iScience | 2024 | |
Falace, Antonio et al. | FLNA regulates neuronal maturation by modulating RAC1-Cofilin activity in the developing cortex | Neurobiology of Disease | 2024 | |
Bahcheli, Alexander T. et al. | Pan-cancer ion transport signature reveals functional regulators of glioblastoma aggression | The EMBO journal | 2024 | |
Hao, Jing et al. | Sema3C signaling is an alternative activator of the canonical WNT pathway in glioblastoma | Nature Communications 2023 14:1 | 2023 | |
Fu, Lisheng et al. | Septin11 promotes hepatocellular carcinoma cell motility by activating RhoA to regulate cytoskeleton and cell adhesion | Cell Death & Disease 2023 14:4 | 2023 | |
Chen, Di et al. | Knockdown of Porf-2 restores visual function after optic nerve crush injury | Cell Death & Disease | 2023 | |
Serwe, Guillaume et al. | CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signalling | Nature Communications | 2023 | |
Kamata, Tamihiro et al. | Statins mediate anti- and pro-tumourigenic functions by remodelling the tumour microenvironment | DMM Disease Models and Mechanisms | 2022 | |
Flores-Muñoz, Carolina et al. | The Long-Term Pannexin 1 Ablation Produces Structural and Functional Modifications in Hippocampal Neurons | Cells | 2022 | |
Chen, Bo et al. | Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor | Journal of Neuroinflammation | 2022 | |
Sha, Zhilin et al. | Hepatic Ischemia-reperfusion Injury in Mice was Alleviated by Rac1 Inhibition – More Than Just ROS-inhibition | Journal of Clinical and Translational Hepatology | 2022 | |
An, Ni et al. | Inhibition of Rac1 attenuates radiation-induced lung injury while suppresses lung tumor in mice | Cell Death Discovery | 2022 | |
Weddle, Erin A. et al. | The type three secretion system effector protein IpgB1 promotes Shigella flexneri cell-to-cell spread through double-membrane vacuole escape | PLoS Pathogens | 2022 | |
Li, Jingxuan et al. | Eva1a ameliorates atherosclerosis by promoting re-endothelialization of injured arteries via Rac1/Cdc42/Arpc1b | Cardiovascular Research | 2021 | |
Kalargyrou, Aikaterini A et al. | Nanotube‐like processes facilitate material transfer between photoreceptors | EMBO reports | 2021 | |
Romano, Roberta et al. | Alteration of the late endocytic pathway in Charcot-Marie-Tooth type 2B disease | Cellular and molecular life sciences : CMLS | 2021 | |
Romano, Roberta et al. | Alteration of the late endocytic pathway in Charcot–Marie–Tooth type 2B disease | Cellular and Molecular Life Sciences | 2021 | |
Afanasyeva, Elena A. et al. | Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma | Life Science Alliance | 2021 | |
Kim, Yeon Sun et al. | Cannabinoid and planar cell polarity signaling converges to direct placentation | Proceedings of the National Academy of Sciences of the United States of America | 2021 | |
Floerchinger, Alessia et al. | Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging | Cell Reports | 2021 | |
Pickering, K. A. et al. | A RAC-GEF network critical for early intestinal tumourigenesis | Nature Communications | 2021 | |
Miroshnikova, Yekaterina A. et al. | Calcium signaling mediates a biphasic mechanoadaptive response of endothelial cells to cyclic mechanical stretch | Molecular Biology of the Cell | 2021 | |
Arandjelovic, Sanja et al. | ELMO1 signaling is a promoter of osteoclast function and bone loss | Nature Communications | 2021 | |
Löber, Jens et al. | Vav family proteins constitute disparate branching points for distinct BCR signaling pathways | European Journal of Immunology | 2020 | |
Guo, Yaxiu et al. | Cytotoxic necrotizing factor 1 promotes bladder cancer angiogenesis through activating RhoC | FASEB Journal | 2020 | |
Won, So Yeon et al. | Fibulin 5, a human Wharton's jelly-derived mesenchymal stem cells-secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin-RAC1 signaling axis | Stem Cells | 2020 | |
Lo, Louisa Hoi Ying et al. | The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation | Cell Reports | 2020 | |
Fulmer, Diana et al. | Desert hedgehog-primary cilia cross talk shapes mitral valve tissue by organizing smooth muscle actin | Developmental Biology | 2020 | |
Kogler, Melanie et al. | HACE1 prevents lung carcinogenesis via inhibition of RAC-Family GTPases | Cancer Research | 2020 | |
Tilve, Sharada et al. | Phospholipid phosphatase related 1 (PLPPR1) increases cell adhesion through modulation of Rac1 activity | Experimental Cell Research | 2020 | |
Draicchio, Fulvia et al. | Integrin-associated ILK and PINCH1 protein content are reduced in skeletal muscle of maintenance haemodialysis patients | Journal of Physiology | 2020 | |
Fray, Michael A. et al. | Vav2 lacks Ca2+entry-promoting scaffolding functions unique to Vav1 and inhibits T cell activation via Cdc42 | Journal of Cell Science | 2020 | |
Lorenzo-Martín, L. Francisco et al. | Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor | Oncogene | 2020 | |
Frye, Maike et al. | Ephrinb2-ephb4 signalling provides rho-mediated homeostatic control of lymphatic endothelial cell junction integrity | eLife | 2020 | |
Goulielmaki, Evi et al. | Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage | Nature Communications | 2020 | |
D'Amore, Claudio et al. | “Janus” efficacy of CX-5011: CK2 inhibition and methuosis induction by independent mechanisms | Biochimica et Biophysica Acta - Molecular Cell Research | 2020 | |
Rodríguez-Fdez, Sonia et al. | Vav2 catalysis-dependent pathways contribute to skeletal muscle growth and metabolic homeostasis | Nature Communications | 2020 | |
Singh, Rajesh K. et al. | Dynamic Actin Reorganization and Vav/Cdc42-Dependent Actin Polymerization Promote Macrophage Aggregated LDL (Low-Density Lipoprotein) Uptake and Catabolism | Arteriosclerosis, Thrombosis, and Vascular Biology | 2019 | |
Balaji Ragunathrao, Vijay Avin et al. | Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling | Cell Reports | 2019 | |
Huang, Yuxing et al. | Arp2/3-branched actin maintains an active pool of GTP-RhoA and controls RhoA abundance | Cells | 2019 | |
Ramadass, Mahalakshmi et al. | The trafficking protein JFC1 regulates Rac1-GTP localization at the uropod controlling neutrophil chemotaxis and in vivo migration | Journal of Leukocyte Biology | 2019 | |
Wong, Bin Sheng et al. | A direct podocalyxin–dynamin-2 interaction regulates cytoskeletal dynamics to promote migration and metastasis in pancreatic cancer cells | Cancer Research | 2019 | |
Chellini, Lidia et al. | Regulation of extracellular matrix degradation and metastatic spread by IQGAP1 through endothelin-1 receptor signalling in ovarian cancer | Matrix Biology | 2019 | |
Dudvarski Stanković, Nevenka et al. | EGFL7 enhances surface expression of integrin α 5 β 1 to promote angiogenesis in malignant brain tumors | EMBO Molecular Medicine | 2018 | |
Hayes, Madeline N. et al. | Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma | Cell Stem Cell | 2018 | |
Wu, Yuqing et al. | Mycobacterial infection is promoted by neutral sphingomyelinase 2 regulating a signaling cascade leading to activation of β1-integrin | Cellular Physiology and Biochemistry | 2018 | |
Chen, Yuxiao et al. | Restoring striatal WAVE-1 improves maze exploration performance of GluN1 knockdown mice | PLoS ONE | 2018 | |
Murillo, Miguel M. et al. | Disruption of the Interaction of RAS with PI 3-Kinase Induces Regression of EGFR-Mutant-Driven Lung Cancer | Cell Reports | 2018 | |
Raun, Steffen H. et al. | Rac1 muscle knockout exacerbates the detrimental effect of high-fat diet on insulin-stimulated muscle glucose uptake independently of Akt | Journal of Physiology | 2018 | |
Stierwalt, Harrison D. et al. | Insulin-stimulated Rac1-GTP binding is not impaired by palmitate treatment in L6 myotubes | Physiological Reports | 2018 | |
Mills, Shirley C. et al. | Rac1 plays a role in CXCL12 but not CCL3-induced chemotaxis and Rac1 GEF inhibitor NSC23766 has off target effects on CXCR4 | Cellular Signalling | 2018 | |
Olthoff, John T. et al. | Loss of peroxiredoxin-2 exacerbates eccentric contraction-induced force loss in dystrophin-deficient muscle | Nature Communications | 2018 | |
Poudel, Kumud R. et al. | Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer Metastasis | Developmental Cell | 2018 | |
Cheng, Yuyan et al. | TNFα disrupts blood brain barrier integrity to maintain prolonged depressive-like behavior in mice | Brain, Behavior, and Immunity | 2018 | |
Bucka, Kenneth B. et al. | Local Arp2/3-dependent actin assembly modulates applied traction force during apCAM adhesion site maturation | Molecular Biology of the Cell | 2017 | |
Tarr, Joseph T. et al. | The pivotal role of CCN2 in mammalian palatogenesis | Journal of Cell Communication and Signaling | 2017 | |
Atala, Anthony | Re: AKT-Mediated Stabilization of Histone Methyltransferase WHSC1 Promotes Prostate Cancer Metastasis | The Journal of urology | 2017 | |
Gao, Jie et al. | The E3 ubiquitin ligase IDOL regulates synaptic ApoER2 levels and is important for plasticity and learning | eLife | 2017 | |
Margiotta, Azzurra et al. | Rab7a regulates cell migration through Rac1 and vimentin | Biochimica et Biophysica Acta - Molecular Cell Research | 2017 | |
Nakamuta, Shinichi et al. | Dual role for DOCK7 in tangential migration of interneuron precursors in the postnatal forebrain | Journal of Cell Biology | 2017 | |
Sylow, Lykke et al. | Rac1 and AMPK account for the majority of muscle glucose uptake stimulated by ex vivo contraction but not in vivo exercise | Diabetes | 2017 | |
Barrera-Chimal, Jonatan et al. | Benefit of mineralocorticoid receptor antagonism in AKI: Role of vascular smooth muscle Rac1 | Journal of the American Society of Nephrology | 2017 | |
Moodley, Serisha et al. | Stimulus-dependent dissociation between XB130 and Tks5 scaffold proteins promotes airway epithelial cell migration | Oncotarget | 2016 | |
Wang, Hui et al. | LOVTRAP: An optogenetic system for photoinduced protein dissociation | Nature Methods | 2016 | |
Sabbir, Mohammad G. et al. | Dlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activation | Biology Open | 2016 | |
Cui, Hong Yong et al. | CD147 regulates cancer migration via direct interaction with Annexin A2 and DOCK3-β-catenin-WAVE2 signaling | Oncotarget | 2016 | |
Gervais, Elise M. et al. | Par-1b is required for morphogenesis and differentiation of myoepithelial cells during salivary gland development | Organogenesis | 2016 | |
Müller, Alena et al. | Comparative study of antitumor effects of bromelain and papain in human cholangiocarcinoma cell lines | International Journal of Oncology | 2016 | |
Seidelin, Jakob Benedict et al. | Cellular inhibitor of apoptosis protein 2 controls human colonic epithelial restitution, migration, and Rac1 activation | American Journal of Physiology - Gastrointestinal and Liver Physiology | 2015 | |
Cao, Xuan et al. | A phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migration | Nature Communications | 2015 | |
Sun, Ling Ling et al. | A three-gene signature and clinical outcome in esophageal squamous cell carcinoma | International Journal of Cancer | 2015 | |
Stanley, Amanda C. et al. | The Rho GTPase Rac1 is required for recycling endosome-mediated secretion of TNF in macrophages | Immunology and Cell Biology | 2014 | |
Mackay, Joanna L. et al. | Simultaneous and independent tuning of RhoA and Rac1 activity with orthogonally inducible promoters | Integrative Biology (United Kingdom) | 2014 | |
Hori, Kei et al. | Cytoskeletal Regulation by AUTS2 in Neuronal Migration and Neuritogenesis | Cell Reports | 2014 | |
Galic, Milos et al. | Dynamic recruitment of the curvature-sensitive protein ArhGAP44 to nanoscale membrane deformations limits exploratory filopodia initiation in neurons | eLife | 2014 | |
Ezzine, Aymen et al. | Recombinant form of mammalian gp91phox is active in the absence of p22phox | Biochemical Journal | 2014 | |
Ko, Hyun Kyung et al. | Suppression of chemotaxis by SSeCKS via scaffolding of phosphoinositol phosphates and the recruitment of the Cdc42 GEF, frabin, to the leading edge | PLoS ONE | 2014 | |
Tong, Junfeng et al. | Phosphorylation of Rac1 T108 by extracellular signal-regulated kinase in response to epidermal growth factor: a novel mechanism to regulate Rac1 function | Molecular and cellular biology | 2013 | |
Buranda, Tione et al. | Rapid parallel flow cytometry assays of active GTPases using effector beads | Analytical Biochemistry | 2013 | |
Huelsenbeck, Stefanie C. et al. | Expression and cytoprotective activity of the small GTPase RhoB induced by the Escherichia coli cytotoxic necrotizing factor 1 | International Journal of Biochemistry and Cell Biology | 2013 | |
Floc'h, Audrey Le et al. | Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse | Journal of Experimental Medicine | 2013 | |
Golden, Sam A. et al. | Epigenetic regulation of RAC1 induces synaptic remodeling in stress disorders and depression | Nature Medicine | 2013 | |
Lehtinen, Laura et al. | 15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells | Journal of Pathology | 2012 | |
Wong, Hon Kit et al. | Merlin/NF2 regulates angiogenesis in schwannomas through a Rac1/semaphorin 3F-dependent mechanism | Neoplasia | 2012 | |
Vidaki, Marina et al. | Rac1-dependent cell cycle exit of MGE precursors and GABAergic interneuron migration to the cortex | Cerebral cortex (New York, N.Y. : 1991) | 2012 | |
Perez, Sylvia E. et al. | Rac1b increases with progressive tau pathology within cholinergic nucleus basalis neurons in alzheimer's disease | American Journal of Pathology | 2012 | |
Härmä, V. et al. | Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models | Oncogene | 2012 | |
Cheadle, Lucas et al. | The novel synaptogenic protein farp1 links postsynaptic cytoskeletal dynamics and transsynaptic organization | Journal of Cell Biology | 2012 | |
Khan, Omar M. et al. | Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice | Journal of Clinical Investigation | 2011 | |
Orange, Jordan S. et al. | IL-2 induces a WAVE2-dependent pathway for actin reorganization that enables WASp-independent human NK cell function | Journal of Clinical Investigation | 2011 | |
Castillo-Lluva, Sonia et al. | SUMOylation of the GTPase Rac1 is required for optimal cell migration | Nature Cell Biology | 2010 | |
Su, Shih Chi et al. | Annexin 2 regulates endothelial morphogenesis by controlling AKT activation and junctional integrity | Journal of Biological Chemistry | 2010 | |
Thomas, Penny S. et al. | Neural crest cell-specific deletion of Rac1 results in defective cell-matrix interactions and severe craniofacial and cardiovascular malformations | Developmental Biology | 2010 | |
Duan, Lei et al. | Distinct roles for Rho Versus Rac/Cdc42 GTPases downstream of Vav2 in regulating mammary epithelial acinar architecture | Journal of Biological Chemistry | 2010 | |
Ford-Speelman, Diana L. et al. | The rho-guanine nucleotide exchange factor domain of obscurin activates rhoA signaling in skeletal muscle | Molecular Biology of the Cell | 2009 | |
Hsu, Hsiang Hao et al. | Mechanisms of angiotensin II signaling on cytoskeleton of podocytes | Journal of Molecular Medicine | 2008 | |
Mitchell, Troy et al. | Primary granule exocytosis in human neutrophils is regulated by Rac-dependent actin remodeling | American Journal of Physiology - Cell Physiology | 2008 | |
Ivanov, Andrei I. et al. | Myosin II regulates the shape of three-dimensional intestinal epithelial cysts | Journal of Cell Science | 2008 | |