Cytoskeleton Inc Antibody Validation Data and Citations

Antibody Citations

AuthorTitleJournalYearArticle Link
Chen, Yihe et al.The BK Channel Limits the Pro-Inflammatory Activity of MacrophagesCells2024
Reedy, Jennifer L. et al.Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxingNature Communications 2024
Eberhard, Daniel et al.Semaphorin-3A regulates liver sinusoidal endothelial cell porosity and promotes hepatic steatosisNature Cardiovascular Research 2024
Przyklenk, Matthias et al.ANTXR1 deficiency promotes fibroblast senescence: implications for GAPO syndrome as a progeroid disorderScientific Reports 2024
Song, Yang et al.Biphasic regulation of epigenetic state by matrix stiffness during cell reprogrammingScience Advances2024
Politiek, Frouwkje A. et al.Molecular and cellular consequences of mevalonate kinase deficiencyBiochimica et Biophysica Acta (BBA)2024
Müller, Lisa et al.Plakophilin 4 controls the spatio-temporal activity of RhoA at adherens junctions to promote cortical actin ring formation and tissue tensionCellular and Molecular Life Sciences2024
Liu, Xiaomin et al.RABV induces biphasic actin cytoskeletal rearrangement through Rac1 activity modulationJournal of Virology2024
Wang, Kui et al.Vascular endothelial cellular mechanics under hyperglycemia and its role in tissue regenerationRegenerative Biomaterials2024
Sen, Buer et al.Nuclear actin structure regulates chromatin accessibilityNature Communications2024
Baudouin, Lucas et al.Antagonistic actions of PAK1 and NF2/Merlin drive myelin membrane expansion in oligodendrocytesGLIA2024
Gao, Da Peng et al.Chronic Alcohol Exposure Alters the Levels and Assembly of the Actin Cytoskeleton and Microtubules in the Adult Mouse HippocampusJournal of Integrative Neuroscience2024
Kamnev, Anton et al.Coordinated ARP2/3 and glycolytic activities regulate the morphological and functional fitness of human CD8+ T cellsCell reports2024
Yin, Xiufeng et al.CFL1 is Implicated in Chronic Myeloid Leukemia Response during Imatinib TherapyJournal of Cancer2024
Medina-Dols, Aina et al.Role of PATJ in stroke prognosis by modulating endothelial to mesenchymal transition through the Hippo/Notch/PI3K axisCell Death Discovery 2024
Li, Yuan Bao et al.Fimbrin associated with Pmk1 to regulate the actin assembly during Magnaporthe oryzae hyphal growth and infectionStress Biology2024
Wang, Lingling et al.Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actinReproductive Biology and Endocrinology 2024
Yu, Jinhan et al.Inhibiting F-Actin Polymerization Impairs the Internalization of Moraxella catarrhalisMicroorganisms 2024
Kinnart, Inge et al.Elevated α-synuclein levels inhibit mitophagic fluxnpj Parkinson's Disease2024
Omer, Safia et al.Ninein promotes F-actin cup formation and inward phagosome movement during phagocytosis in macrophagesMolecular biology of the cell2024
Gorshkova, Irina N. et al.Human apoA-I[Lys107del] mutation affects lipid surface behavior of apoA-I and its ability to form large nascent HDLJournal of Lipid Research2023
Prasad, Vibhu et al.Enhanced SARS-CoV-2 entry via UPR-dependent AMPK-related kinase NUAK2Molecular cell2023
Rakotomamonjy, Jennifer et al.PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid modelCell reports2023
Du, William W. et al.Nuclear Actin Polymerization Regulates Cell Epithelial-Mesenchymal TransitionAdvanced Science2023
Levy-Myers, Reuben et al.An independent regulator of global release pathways in astrocytes generates a subtype of extracellular vesicles required for postsynaptic functionScience Advances2023
Faria, Lídia et al.Activation of an actin signaling pathway in pre-malignant mammary epithelial cells by P-cadherin is essential for transformationDisease Models & Mechanisms2023
Romero, Luis O. et al.Linoleic acid improves PIEZO2 dysfunction in a mouse model of Angelman SyndromeNature Communications2023
Lohraseb, Iman et al.Global ubiquitinome profiling identifies NEDD4 as a regulator of Profilin 1 and actin remodelling in neural crest cellsNature Communications2022
Fang, Shi et al.RhoBTB1 reverses established arterial stiffness in angiotensin II–induced hypertension by promoting actin depolymerizationJCI Insight2022
Garcia, Alix et al.miR-204-5p and Platelet Function Regulation: Insight into a Mechanism Mediated by CDC42 and GPIIbIIIaThrombosis and haemostasis2021
Nanamatsu, Azuma et al.Vas******** Induces Urinary Uromodulin Secretion by Activating PKA (Protein Kinase A)Hypertension2021
Wang, Dawei et al.Capping protein regulates endosomal trafficking by controlling f-actin density around endocytic vesicles and recruiting rab5 effectorseLife2021
AuthorTitleJournalYearArticle Link
Romero, Ana M. et al.Chronic alcohol alters dendritic spine development in neurons in primary cultureNeurotoxicity research2013
Osiak, Anna Eleonor et al.Subconfluent endothelial cells form podosomes downstream of cytokine and RhoGTPase signalingExperimental cell research2005
Hernández-Deviez, Delia J. et al.ARNO and ARF6 regulate axonal elongation and branching through downstream activation of phosphatidylinositol 4-phosphate 5-kinase alphaMolecular biology of the cell2004
Innocenti, Metello et al.Abi1 is essential for the formation and activation of a WAVE2 signalling complexNature cell biology2004
Tang, Dale D. et al.Role of Crk-Associated Substrate in the Regulation of Vascular Smooth Muscle ContractionHypertension2003
Tang, Dale D. et al.Downregulation of profilin with antisense oligodeoxynucleotides inhibits force development during stimulation of smooth muscleAmerican journal of physiology. Heart and circulatory physiology2003
AuthorTitleJournalYearArticle Link
Son, Sung Min et al.p300 nucleocytoplasmic shuttling underlies mTORC1 hyperactivation in Hutchinson–Gilford progeria syndromeNature Cell Biology 2024 26:22024
Martins, Vitor F. et al.p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytesJCI Insight2022
Martins, Vitor F. et al.p300 or CBP is required for insulinstimulated glucose uptake in skeletal muscle and adipocytesJCI Insight2022
Martins, Vitor F. et al.Germline or inducible knockout of p300 or cbp in skeletal muscle does not alter insulin sensitivityAmerican Journal of Physiology - Endocrinology and Metabolism2019
Sharma, Monica et al.Acetylation of conserved DVL-1 lysines regulates its nuclear translocation and binding to gene promoters in triple-negative breast cancerScientific Reports2019
Ishihara, Akinori et al.Seasonal acclimatization and thermal acclimation induce global histone epigenetic changes in liver of bullfrog (Lithobates catesbeianus) tadpoleComparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology2019
Yang, Youyun et al.Identification of acetylated proteins in Borrelia burgdorferiMethods in Molecular Biology2018
Horita, Henrick et al.Utilizing a comprehensive immunoprecipitation enrichment system to identify an endogenous post-translational modification profile for target proteinsJournal of Visualized Experiments2018
Horita, Henrick et al.A simple toolset to identify endogenous post-translational modifications for a target protein: A snapshot of the EGFR signaling pathwayBioscience Reports2017
Horita, Henrick et al.Identifying Regulatory Posttranslational Modifications of PD-L1: A Focus on MonoubiquitinatonNeoplasia (United States)2017
LaBarge, Samuel A. et al.P300 is not required for metabolic adaptation to endurance exercise trainingFASEB Journal2016
AuthorTitleJournalYearArticle Link
Ahmed, Farjana et al.Human N-Alpha-Acetyltransferase 60 Promotes Influenza A Virus Infection by Dampening the Interferon Alpha SignalingFrontiers in Immunology2022
Ahmed, Farjana et al.Human N-Alpha-Acetyltransferase 60 Promotes Influenza A Virus Infection by Dampening the Interferon Alpha SignalingFrontiers in Immunology2022
Vega, Maria E. et al.Stimulation of Fibronectin Matrix Assembly by Lysine AcetylationCells2020
Aon, Miguel A. et al.Untangling Determinants of Enhanced Health and Lifespan through a Multi-omics Approach in MiceCell Metabolism2020
Elhassan, Yasir S. et al.Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory SignaturesCell Reports2019
Horita, Henrick et al.Utilizing optimized tools to investigate PTM crosstalk: Identifying potential PTM crosstalk of acetylated mitochondrial proteinsProteomes2018
AuthorTitleJournalYearArticle Link
Yasuda, Tatsuki et al.Mitochondrial dynamics define muscle fiber type by modulating cellular metabolic pathwaysCell Reports2023
Horita, Henrick et al.Utilizing optimized tools to investigate PTM crosstalk: Identifying potential PTM crosstalk of acetylated mitochondrial proteinsProteomes2018
AuthorTitleJournalYearArticle Link
Vega, Maria E. et al.Stimulation of Fibronectin Matrix Assembly by Lysine AcetylationCells2020
Aon, Miguel A. et al.Untangling Determinants of Enhanced Health and Lifespan through a Multi-omics Approach in MiceCell Metabolism2020
AuthorTitleJournalYearArticle Link
Ahler, Ethan et al.A Combined Approach Reveals a Regulatory Mechanism Coupling Src's Kinase Activity, Localization, and Phosphotransferase-Independent FunctionsMolecular Cell2019
Kline, Ashley et al.The Misshapen kinase regulates the size and stability of the germline ring canals in the Drosophila egg chamberDevelopmental Biology2018
Seki, Takahiro et al.Ablation of endothelial VEG FR1 improves metabolic dysfunction by inducing adipose tissue browningJournal of Experimental Medicine2018
Cheng, Larry C. et al.Phosphopeptide enrichment coupled with label-free quantitative mass spectrometry to investigate the phosphoproteome in prostate cancerJournal of Visualized Experiments2018
Horita, Henrick et al.Utilizing a comprehensive immunoprecipitation enrichment system to identify an endogenous post-translational modification profile for target proteinsJournal of Visualized Experiments2018
Horita, Henrick et al.Utilizing optimized tools to investigate PTM crosstalk: Identifying potential PTM crosstalk of acetylated mitochondrial proteinsProteomes2018
Horita, Henrick et al.A simple toolset to identify endogenous post-translational modifications for a target protein: A snapshot of the EGFR signaling pathwayBioscience Reports2017
Horita, Henrick et al.Identifying Regulatory Posttranslational Modifications of PD-L1: A Focus on MonoubiquitinatonNeoplasia (United States)2017
Kaukonen, Riina et al.Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcriptionNature Communications2016
AuthorTitleJournalYearArticle Link
Colussi, Claudia et al.Cytoplasmic HDAC4 recovers synaptic function in the 3×Tg mouse model of Alzheimer's diseaseNeuropathology and Applied Neurobiology2023
AuthorTitleJournalYearArticle Link
Garvin, Alexander J. et al.SUMO monoclonal antibodies vary in sensitivity, specificity, and ability to detect types of SUMO conjugateScientific Reports2022
Garvin, Alexander J. et al.SUMO monoclonal antibodies vary in sensitivity, specificity, and ability to detect types of SUMO conjugateScientific Reports2022
Zhao, Rongwei et al.Chemical dimerization-induced protein condensates on telomeresJournal of Visualized Experiments2021
Juncker, Meredith et al.ISG15 attenuates post-translational modifications of mitofusins and congression of damaged mitochondria in Ataxia Telangiectasia cellsBiochimica et Biophysica Acta - Molecular Basis of Disease2021
Pronot, Marie et al.Proteomic Identification of an Endogenous Synaptic SUMOylome in the Developing Rat BrainFrontiers in Molecular Neuroscience2021
Kim, Catherine et al.SUMOylation of mitofusins: A potential mechanism for perinuclear mitochondrial congression in cells treated with mitochondrial stressorsBiochimica et Biophysica Acta - Molecular Basis of Disease2021
Zhou, Liwen et al.SUMOylation stabilizes hSSB1 and enhances the recruitment of NBS1 to DNA damage sitesSignal Transduction and Targeted Therapy2020
Yan, Yao Long et al.DPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate zygotic transcriptional programPLoS Biology2019
AuthorTitleJournalYearArticle Link
Juncker, Meredith et al.ISG15 attenuates post-translational modifications of mitofusins and congression of damaged mitochondria in Ataxia Telangiectasia cellsBiochimica et Biophysica Acta - Molecular Basis of Disease2021
Kim, Catherine et al.SUMOylation of mitofusins: A potential mechanism for perinuclear mitochondrial congression in cells treated with mitochondrial stressorsBiochimica et Biophysica Acta - Molecular Basis of Disease2021
Zhou, Liwen et al.SUMOylation stabilizes hSSB1 and enhances the recruitment of NBS1 to DNA damage sitesSignal Transduction and Targeted Therapy2020
AuthorTitleJournalYearArticle Link
Garvin, Alexander J. et al.SUMO monoclonal antibodies vary in sensitivity, specificity, and ability to detect types of SUMO conjugateScientific Reports2022
Kim, Catherine et al.SUMOylation of mitofusins: A potential mechanism for perinuclear mitochondrial congression in cells treated with mitochondrial stressorsBiochimica et Biophysica Acta - Molecular Basis of Disease2021
AuthorTitleJournalYearArticle Link
Plooy, Lukas M. du et al.A fungal ubiquitin ligase and arrestin binding partner contribute to pathogenesis and survival during cellular stressmBio2024
Pino-Belmar, Camila et al.An Intrinsic Host Defense against HSV-1 Relies on the Activation of Xenophagy with the Active Clearance of Autophagic ReceptorsCells 2024
Takeda, Kenji et al.A Novel Approach: Investigating the Intracellular Clearance Mechanism of Glyceraldehyde-Derived Advanced Glycation End-Products Using the Artificial Checkpoint Kinase 1 d270KD Mutant as a Substrate ModelCells2023
Martin, Thomas G. et al.Dysregulated Autophagy and Sarcomere Dysfunction in Patients With Heart Failure With Co-Occurrence of P63A and P380S BAG3 VariantsJournal of the American Heart Association2023
Wang, Longlong et al.Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathwaysCell Reports2022
Martin, Thomas G. et al.Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnoverNature Communications2021
Manzione, Maria Giulia et al.Co-regulation of the antagonistic RepoMan:Aurora-B pair in proliferating cellsMolecular Biology of the Cell2020
Rivas, José et al.KCTD5, a novel TRPM4-regulatory protein required for cell migration as a new predictor for breast cancer prognosisFASEB Journal2020
Wenzel, H. Jürgen et al.Astroglial-targeted expression of the fragile X CGG repeat premutation in mice yields RAN translation, motor deficits and possible evidence for cell-to-cell propagation of FXTAS pathologyActa neuropathologica communications2019
Álvarez, Alhejandra et al.KCTD5 and ubiquitin proteasome signaling are required for Helicobacter pylori adherenceFrontiers in Cellular and Infection Microbiology2017
Braganza, Andrea et al.UBE3B is a calmodulin-regulated, mitochondrion-associated E3 ubiquitin ligaseJournal of Biological Chemistry2017
Horita, Henrick et al.Identifying Regulatory Posttranslational Modifications of PD-L1: A Focus on MonoubiquitinatonNeoplasia (United States)2017
Hukema, Renate K. et al.Reversibility of neuropathology and motor deficits in an inducible mouse model for FXTASHuman Molecular Genetics2015
AuthorTitleJournalYearArticle Link
Liu, Fan et al.BAK1 protects the receptor-like kinase BIR2 from SNIPER2a/b-mediated degradation to promote pattern-triggered immunity in Nicotiana benthamianaThe Plant Cell2023
de Mello, Aline Haas et al.Hydrogen Sulfide Donor GYY4137 Rescues NRF2 Activation in Respiratory Syncytial Virus InfectionAntioxidants2022
Horita, Henrick et al.Identifying Regulatory Posttranslational Modifications of PD-L1: A Focus on MonoubiquitinatonNeoplasia (United States)2017
AuthorTitleJournalYearArticle Link
Jayabal, Panneerselvam et al.Roles of USP1 in Ewing sarcomaGenes & Cancer2024
Ledoux, Benjamin et al.Plasma membrane nanodeformations promote actin polymerization through CIP4/CDC42 recruitment and regulate type II IFN signalingScience Advances2023
Fu, Lisheng et al.Septin11 promotes hepatocellular carcinoma cell motility by activating RhoA to regulate cytoskeleton and cell adhesionCell Death & Disease 2023 14:42023
Serwe, Guillaume et al.CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signallingNature Communications2023
Kamata, Tamihiro et al.Statins mediate anti- and pro-tumourigenic functions by remodelling the tumour microenvironmentDMM Disease Models and Mechanisms2022
Flores-Muñoz, Carolina et al.The Long-Term Pannexin 1 Ablation Produces Structural and Functional Modifications in Hippocampal NeuronsCells2022
Chen, Bo et al.Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptorJournal of Neuroinflammation2022
Tyckaert, François et al.Rac1, the actin cytoskeleton and microtubules are key players in clathrin-independent endophilin-A3-mediated endocytosisJournal of cell science2022
Kamata, Tamihiro et al.Statins mediate anti- and pro-tumourigenic functions by remodelling the tumour microenvironmentDMM Disease Models and Mechanisms2022
Li, Jingxuan et al.Eva1a ameliorates atherosclerosis by promoting re-endothelialization of injured arteries via Rac1/Cdc42/Arpc1bCardiovascular Research2021
Barbera, Stefano et al.The C-type lectin CD93 controls endothelial cell migration via activation of the Rho family of small GTPasesMatrix Biology2021
Jayabal, Panneerselvam et al.NELL2-cdc42 signaling regulates BAF complexes and Ewing sarcoma cell growthCell Reports2021
Howden, Jake D. et al.α2β1 integrins spatially restrict Cdc42 activity to stabilise adherens junctionsBMC biology2021
Hosseini, Kamran et al.EMT-Induced Cell-Mechanical Changes Enhance Mitotic Rounding StrengthAdvanced Science2020
Gorisse, Laetitia et al.Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42Journal of Biological Chemistry2020
Oni, Tobiloba E. et al.SOAT1 promotes mevalonate pathway dependency in pancreatic cancerJournal of Experimental Medicine2020
Gu, Jiawen et al.Rho-GEF trio regulates osteoclast differentiation and function by Rac1/Cdc42Experimental Cell Research2020
Singh, Rajesh K. et al.Dynamic Actin Reorganization and Vav/Cdc42-Dependent Actin Polymerization Promote Macrophage Aggregated LDL (Low-Density Lipoprotein) Uptake and CatabolismArteriosclerosis, Thrombosis, and Vascular Biology2019
Huang, Yuxing et al.Arp2/3-branched actin maintains an active pool of GTP-RhoA and controls RhoA abundanceCells2019
Dupraz, Sebastian et al.RhoA Controls Axon Extension Independent of Specification in the Developing BrainCurrent Biology2019
Vestre, Katharina et al.Rab6 regulates cell migration and invasion by recruiting Cdc42 and modulating its activityCellular and Molecular Life Sciences2019
MacKeil, Jodi L. et al.Phosphodiesterase 3B (PDE3B) antagonizes the anti-angiogenic actions of PKA in human and murine endothelial cellsCellular Signalling2019
Dudvarski Stanković, Nevenka et al. EGFL7 enhances surface expression of integrin α 5 β 1 to promote angiogenesis in malignant brain tumors EMBO Molecular Medicine2018
Wu, Nan et al.RCC2 over-expression in tumor cells alters apoptosis and drug sensitivity by regulating Rac1 activationBMC Cancer2018
Peretti, Amanda S. et al.The R-Enantiomer of Keto***** Delays Mammary Tumor Development in Mouse Mammary Tumor Virus-Polyoma Middle T Antigen (MMTV-PyMT) MiceAmerican Journal of Pathology2018
Liu, Xiaolei et al.Rasip1 controls lymphatic vessel lumen maintenance by regulating endothelial cell junctionsDevelopment (Cambridge)2018
Lam, Jonathan G.T. et al.Host cell perforation by listeriolysin O (LLO) activates a Ca2+-dependent cPKC/Rac1/Arp2/3 signaling pathway that promotes Listeria monocytogenes internalization independently of membrane resealingMolecular Biology of the Cell2018
Li, Cao et al.Regulation of staphylococcus aureus infection of macrophages by CD44, reactive oxygen species, and acid sphingomyelinaseAntioxidants and Redox Signaling2018
Ghézali, Grégory et al.Connexin 30 controls astroglial polarization during postnatal brain developmentDevelopment (Cambridge)2018
Kawasaki, Natsumi et al.TUFT1 interacts with RABGAP1 and regulates mTORC1 signalingCell Discovery2018
Stypulkowski, Ewa et al.The depalmitoylase APT1 directs the asymmetric partitioning of Notch and Wnt signaling during cell divisionScience Signaling2018
Vodicska, Barbara et al.MISP regulates the IQGAP1/Cdc42 complex to collectively orchestrate spindle orientation and mitotic progressionScientific Reports2018
Bucka, Kenneth B. et al.Local Arp2/3-dependent actin assembly modulates applied traction force during apCAM adhesion site maturationMolecular Biology of the Cell2017
Chang, Ting Ya et al.Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machineryeLife2017
Saito, Masaki et al.Tctex‐1 controls ciliary resorption by regulating branched actin polymerization and endocytosisEMBO reports2017
Takeuchi, Hiroki et al.Intracellular periodontal pathogen exploits recycling pathway to exit from infected cellsCellular Microbiology2016
Seidelin, Jakob Benedict et al.Cellular inhibitor of apoptosis protein 2 controls human colonic epithelial restitution, migration, and Rac1 activationAmerican Journal of Physiology - Gastrointestinal and Liver Physiology2015
Thomas, Audrey et al.Involvement of the Rac1-IRSp53-Wave2-Arp2/3 Signaling Pathway in HIV-1 Gag Particle Release in CD4 T CellsJournal of Virology2015
Liu, Chunqiao et al.Null and hypomorph Prickle1 alleles in mice phenocopy human Robinow syndrome and disrupt signaling downstream of Wnt5aBiology Open2014
David, Muriel D. et al.The RhoGAP ARHGAP19 controls cytokinesis and chromosome segregation in T lymphocytesJournal of Cell Science2014
Valtcheva, Nadejda et al.The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42Journal of Biological Chemistry2013
Barrio, Laura et al.TLR4 Signaling Shapes B Cell Dynamics via MyD88-Dependent Pathways and Rac GTPasesThe Journal of Immunology2013
Steele, Brian M. et al.WNT-3a modulates platelet function by regulating small GTPase activityFEBS Letters2012
Mercer, Jason et al.Vaccinia virus strains use distinct forms of macropinocytosis for host-cell entryProceedings of the National Academy of Sciences of the United States of America2010
AuthorTitleJournalYearArticle Link
Li, Fuxiang et al.SIRT7 remodels the cytoskeleton via RAC1 to enhance host resistance to Mycobacterium tuberculosismBio2024
Martin, Lee J. et al.Nuclear Localization of Human SOD1 in Motor Neurons in Mouse Model and Patient Amyotrophic Lateral Sclerosis: Possible Links to Cholinergic Phenotype, NADPH Oxidase, Oxidative Stress, and DNA DamageInternational Journal of Molecular Sciences2024
Voglewede, Mikayla M. et al.Loss of the polarity protein Par3 promotes dendritic spine neoteny and enhances learning and memoryiScience2024
Falace, Antonio et al.FLNA regulates neuronal maturation by modulating RAC1-Cofilin activity in the developing cortexNeurobiology of Disease2024
Bahcheli, Alexander T. et al.Pan-cancer ion transport signature reveals functional regulators of glioblastoma aggressionThe EMBO journal2024
Hao, Jing et al.Sema3C signaling is an alternative activator of the canonical WNT pathway in glioblastomaNature Communications 2023 14:12023
Fu, Lisheng et al.Septin11 promotes hepatocellular carcinoma cell motility by activating RhoA to regulate cytoskeleton and cell adhesionCell Death & Disease 2023 14:42023
Chen, Di et al.Knockdown of Porf-2 restores visual function after optic nerve crush injuryCell Death & Disease2023
Serwe, Guillaume et al.CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signallingNature Communications2023
Kamata, Tamihiro et al.Statins mediate anti- and pro-tumourigenic functions by remodelling the tumour microenvironmentDMM Disease Models and Mechanisms2022
Flores-Muñoz, Carolina et al.The Long-Term Pannexin 1 Ablation Produces Structural and Functional Modifications in Hippocampal NeuronsCells2022
Chen, Bo et al.Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptorJournal of Neuroinflammation2022
Sha, Zhilin et al.Hepatic Ischemia-reperfusion Injury in Mice was Alleviated by Rac1 Inhibition – More Than Just ROS-inhibitionJournal of Clinical and Translational Hepatology2022
An, Ni et al.Inhibition of Rac1 attenuates radiation-induced lung injury while suppresses lung tumor in miceCell Death Discovery2022
Weddle, Erin A. et al.The type three secretion system effector protein IpgB1 promotes Shigella flexneri cell-to-cell spread through double-membrane vacuole escapePLoS Pathogens2022
Li, Jingxuan et al.Eva1a ameliorates atherosclerosis by promoting re-endothelialization of injured arteries via Rac1/Cdc42/Arpc1bCardiovascular Research2021
Kalargyrou, Aikaterini A et al.Nanotube‐like processes facilitate material transfer between photoreceptorsEMBO reports2021
Romano, Roberta et al.Alteration of the late endocytic pathway in Charcot-Marie-Tooth type 2B diseaseCellular and molecular life sciences : CMLS2021
Romano, Roberta et al.Alteration of the late endocytic pathway in Charcot–Marie–Tooth type 2B diseaseCellular and Molecular Life Sciences2021
Afanasyeva, Elena A. et al.Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastomaLife Science Alliance2021
Kim, Yeon Sun et al.Cannabinoid and planar cell polarity signaling converges to direct placentationProceedings of the National Academy of Sciences of the United States of America2021
Floerchinger, Alessia et al.Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imagingCell Reports2021
Pickering, K. A. et al.A RAC-GEF network critical for early intestinal tumourigenesisNature Communications2021
Miroshnikova, Yekaterina A. et al.Calcium signaling mediates a biphasic mechanoadaptive response of endothelial cells to cyclic mechanical stretchMolecular Biology of the Cell2021
Arandjelovic, Sanja et al.ELMO1 signaling is a promoter of osteoclast function and bone lossNature Communications2021
Löber, Jens et al.Vav family proteins constitute disparate branching points for distinct BCR signaling pathwaysEuropean Journal of Immunology2020
Guo, Yaxiu et al.Cytotoxic necrotizing factor 1 promotes bladder cancer angiogenesis through activating RhoCFASEB Journal2020
Won, So Yeon et al.Fibulin 5, a human Wharton's jelly-derived mesenchymal stem cells-secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin-RAC1 signaling axisStem Cells2020
Lo, Louisa Hoi Ying et al.The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine MaturationCell Reports2020
Fulmer, Diana et al.Desert hedgehog-primary cilia cross talk shapes mitral valve tissue by organizing smooth muscle actinDevelopmental Biology2020
Kogler, Melanie et al.HACE1 prevents lung carcinogenesis via inhibition of RAC-Family GTPasesCancer Research2020
Tilve, Sharada et al.Phospholipid phosphatase related 1 (PLPPR1) increases cell adhesion through modulation of Rac1 activityExperimental Cell Research2020
Draicchio, Fulvia et al.Integrin-associated ILK and PINCH1 protein content are reduced in skeletal muscle of maintenance haemodialysis patientsJournal of Physiology2020
Fray, Michael A. et al.Vav2 lacks Ca2+entry-promoting scaffolding functions unique to Vav1 and inhibits T cell activation via Cdc42Journal of Cell Science2020
Lorenzo-Martín, L. Francisco et al.Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factorOncogene2020
Frye, Maike et al.Ephrinb2-ephb4 signalling provides rho-mediated homeostatic control of lymphatic endothelial cell junction integrityeLife2020
Goulielmaki, Evi et al.Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damageNature Communications2020
D'Amore, Claudio et al.“Janus” efficacy of CX-5011: CK2 inhibition and methuosis induction by independent mechanismsBiochimica et Biophysica Acta - Molecular Cell Research2020
Rodríguez-Fdez, Sonia et al.Vav2 catalysis-dependent pathways contribute to skeletal muscle growth and metabolic homeostasisNature Communications2020
Singh, Rajesh K. et al.Dynamic Actin Reorganization and Vav/Cdc42-Dependent Actin Polymerization Promote Macrophage Aggregated LDL (Low-Density Lipoprotein) Uptake and CatabolismArteriosclerosis, Thrombosis, and Vascular Biology2019
Balaji Ragunathrao, Vijay Avin et al.Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic SignalingCell Reports2019
Huang, Yuxing et al.Arp2/3-branched actin maintains an active pool of GTP-RhoA and controls RhoA abundanceCells2019
Ramadass, Mahalakshmi et al.The trafficking protein JFC1 regulates Rac1-GTP localization at the uropod controlling neutrophil chemotaxis and in vivo migrationJournal of Leukocyte Biology2019
Wong, Bin Sheng et al.A direct podocalyxin–dynamin-2 interaction regulates cytoskeletal dynamics to promote migration and metastasis in pancreatic cancer cellsCancer Research2019
Chellini, Lidia et al.Regulation of extracellular matrix degradation and metastatic spread by IQGAP1 through endothelin-1 receptor signalling in ovarian cancerMatrix Biology2019
Dudvarski Stanković, Nevenka et al. EGFL7 enhances surface expression of integrin α 5 β 1 to promote angiogenesis in malignant brain tumors EMBO Molecular Medicine2018
Hayes, Madeline N. et al.Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in RhabdomyosarcomaCell Stem Cell2018
Wu, Yuqing et al.Mycobacterial infection is promoted by neutral sphingomyelinase 2 regulating a signaling cascade leading to activation of β1-integrinCellular Physiology and Biochemistry2018
Chen, Yuxiao et al.Restoring striatal WAVE-1 improves maze exploration performance of GluN1 knockdown micePLoS ONE2018
Murillo, Miguel M. et al.Disruption of the Interaction of RAS with PI 3-Kinase Induces Regression of EGFR-Mutant-Driven Lung CancerCell Reports2018
Raun, Steffen H. et al.Rac1 muscle knockout exacerbates the detrimental effect of high-fat diet on insulin-stimulated muscle glucose uptake independently of AktJournal of Physiology2018
Stierwalt, Harrison D. et al.Insulin-stimulated Rac1-GTP binding is not impaired by palmitate treatment in L6 myotubesPhysiological Reports2018
Mills, Shirley C. et al.Rac1 plays a role in CXCL12 but not CCL3-induced chemotaxis and Rac1 GEF inhibitor NSC23766 has off target effects on CXCR4Cellular Signalling2018
Olthoff, John T. et al.Loss of peroxiredoxin-2 exacerbates eccentric contraction-induced force loss in dystrophin-deficient muscleNature Communications2018
Poudel, Kumud R. et al.Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer MetastasisDevelopmental Cell2018
Cheng, Yuyan et al.TNFα disrupts blood brain barrier integrity to maintain prolonged depressive-like behavior in miceBrain, Behavior, and Immunity2018
Bucka, Kenneth B. et al.Local Arp2/3-dependent actin assembly modulates applied traction force during apCAM adhesion site maturationMolecular Biology of the Cell2017
Tarr, Joseph T. et al.The pivotal role of CCN2 in mammalian palatogenesisJournal of Cell Communication and Signaling2017
Atala, AnthonyRe: AKT-Mediated Stabilization of Histone Methyltransferase WHSC1 Promotes Prostate Cancer MetastasisThe Journal of urology2017
Gao, Jie et al.The E3 ubiquitin ligase IDOL regulates synaptic ApoER2 levels and is important for plasticity and learningeLife2017
Margiotta, Azzurra et al.Rab7a regulates cell migration through Rac1 and vimentinBiochimica et Biophysica Acta - Molecular Cell Research2017
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