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In eukaryote cells, cytoplasmic dynein complex (CDC) and kinesin-14 family members are the only two types of motors known to move cargo to the minus-end of microtubules (MTs)1. This function is critical for cell metabolism, structure, and movement. The majority of these processes utilize CDC because of its high fidelity and steady processive movement. CDC’s wide range of roles is impressive and the roles are further defined by ancillary proteins which select cargo or an intracellular location... Click to read more

 

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daren young