Dynamic remodeling of the actin cytoskeleton [i.e., rapid cycling between filamentous actin (F-actin) and monomer actin (G-actin)] is required for multiple physiological functions, including intracellular transport, cell growth, morphology, motility, trafficking, polarity, cell-to-cell contacts, and cytokinesis1,2. Correspondingly, dysfunctional actin cytoskeletal dynamics are a pathophysiological feature of many human diseases, including those with oncogenic, neurodegenerative, or cardiovascular origins3-9. For these reasons, there is continuing interest in F-actin live cell imaging probes to study actin cytoskeletal dynamics in cell culture models of health and disease.
Also included in this newsletter:
- Tubulin and Actin Live Cell Reagents, G-LISA Activation Assay Kits, Tubulin Kits, Actin Biochem Kits
- Related Publications