Integrin-mediated redox control of beta-actin: PDI's Emergence

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Cell migration is an integral part of several biological processes including angiogenesis, wound healing, and immune surveillance(1).  Integrins are αβ heterodimeric transmembrane receptors that link a cell's dynamic interaction with the extracellular matrix (ECM) to the cytoskeletal rearrangements that are necessary to promote cell motility (See figure 1)... Click to read more


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daren young