Kinesin motor proteins regulate mitosis and anterograde cargo transport as exemplified by fast axonal transport (FAT) in neurons. Neurons depend on kinesins for cell cycle regulation, especially the assembly and function of the mitotic spindle, a macromolecular structure composed primarily of microtubules (MTs) that undergo cycles of polymerization and depolymerization to properly segregate duplicate chromosomes into separate daughter cells.
Also included in this newsletter:
- Kinesin & Dynein Proteins, Kits and Assays, and Microtubules
- Related Publications