Ras and Rho Prenylation News


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Ras and Rho GTPases are small G-proteins that cycle between an active GTP-bound form and inactive GDP-bound form.  Ras proteins, known for their role in cell proliferation, and Rho proteins, known for their involvement in cell morphology, have common post-translational modifications (PTMs) that have been identified as contributors to oncogenesis1,2.  Understanding Ras and Rho PTMs have been of interest for drug discovery groups for many years.  Recent studies of signaling pathways mediated by the Ras and Rho PTMs prenylation and/or palmitoylation have identified potential cancer drug targets1,2... Click to read more

 

Also included in this newsletter:

 

  • Ras and Rho Related Publications

 

  • Ras and Rho Protein Research Tools

 

Posted in News By

daren young