Author | Title | Journal | Year | Article Link |
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Popescu, Bogdan et al. | Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML | Cell reports. Medicine | 2023 | ISSN 2666--3791 |
Li, Tianxia et al. | Developing SHP2-based combination therapy for KRAS-amplified cancer | JCI Insight | 2023 | ISSN 2379-3708 |
Baltanás, Fernando C. et al. | Critical requirement of SOS1 for tumor development and microenvironment modulation in KRASG12D-driven lung adenocarcinoma | Nature Communications 2023 14:1 | 2023 | ISSN 2041--1723 |
Peng, Ke et al. | Development of Combination Strategies for Focal Adhesion Kinase Inhibition in Diffuse Gastric Cancer | Clinical Cancer Research | 2023 | ISSN 1557-3265 |
Nataraj, Nishanth Belugali et al. | Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors | Cell Reports | 2022 | ISSN 2211--1247 |
Swaminathan, Bhairavi et al. | Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration | Scientific Reports | 2022 | ISSN 2045-2322 |
Nataraj, Nishanth Belugali et al. | Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors | Cell Reports | 2022 | ISSN 2211-1247 |
Tisi, Renata et al. | The Multi-Level Mechanism of Action of a Pan-Ras Inhibitor Explains its Antiproliferative Activity on Cetuximab-Resistant Cancer Cells | Frontiers in Molecular Biosciences | 2021 | ISSN 2296-889X |
Mao, De Yu et al. | CLIC1 and CLIC4 mediate endothelial S1P receptor signaling to facilitate Rac1 and RhoA activity and function | Science Signaling | 2021 | ISSN 1937-9145 |
Tisi, Renata et al. | The Multi-Level Mechanism of Action of a Pan-Ras Inhibitor Explains its Antiproliferative Activity on Cetux****-Resistant Cancer Cells | Frontiers in Molecular Biosciences | 2021 | ISSN 2296-889X |
Hofmann, Marco H. et al. | Bi-3406, a potent and selective sos1–kras interaction inhibitor, is effective in kras-driven cancers through combined mek inhibition | Cancer Discovery | 2021 | ISSN 2159-8290 |
Wang, Xuesong et al. | Sevof****** inhibits growth factor-induced angiogenesis through suppressing Rac1/paxillin/FAK and Ras/Akt/mTOR | Future oncology (London, England) | 2020 | ISSN 1744--8301 |
Kim, Jin Hee et al. | Rational design of small molecule RHOA inhibitors for gastric cancer | The Pharmacogenomics Journal 2020 20:4 | 2020 | ISSN 1473--1150 |
Lu, Hengyu et al. | Research paper resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR | Oncotarget | 2020 | ISSN 1949-2553 |
Morgan, Chase J. et al. | Endogenous IQGAP1 and IQGAP3 do not functionally interact with Ras | Scientific Reports | 2019 | ISSN 2045-2322 |
Casique-Aguirre, Diana et al. | KRas4B-PDE6δ complex stabilization by small molecules obtained by virtual screening affects Ras signaling in pancreatic cancer 06 Biological Sciences 0601 Biochemistry and Cell Biology | BMC Cancer | 2018 | ISSN 1471-2407 |
Li, Qing fen et al. | Activation of Ras in the Vascular Endothelium Induces Brain Vascular Malformations and Hemorrhagic Stroke | Cell Reports | 2018 | ISSN 2211-1247 |
Zhao, Tuo et al. | Simulated Microgravity Reduces Focal Adhesions and Alters Cytoskeleton and Nuclear Positioning Leading to Enhanced Apoptosis via Suppressing FAK/RhoA-Mediated mTORC1/NF-κB and ERK1/2 Pathways | International Journal of Molecular Sciences | 2018 | ISSN 1422-0067 |
Wong, Gabrielle S. et al. | Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition letter | Nature Medicine | 2018 | ISSN 1546-170X |
Chen, Guo Ping et al. | Inhibition of farnesyl pyrophosphate synthase attenuates high glucose-induced vascular smooth muscle cells proliferation | Molecular Medicine Reports | 2017 | ISSN 1791-3004 |
Huang, Jia Lin et al. | Lipoprotein-biomimetic nanostructure enables efficient targeting delivery of siRNA to Ras-activated glioblastoma cells via macropinocytosis | Nature Communications | 2017 | ISSN 2041-1723 |
Zhao, Chen Ze et al. | Inhibition of farnesyl pyrophosphate synthase improves pressure overload induced chronic cardiac remodeling | Scientific Reports | 2016 | ISSN 2045-2322 |
Lee, Sei Jung et al. | Regulation of Hypoxia-inducible Factor 1α (HIF-1α) by Lysophosphatidic Acid Is Dependent on Interplay between p53 and Krüppel-like Factor 5 | The Journal of Biological Chemistry | 2013 | ISSN 0021-9258 |
Camargo, Livia De Lucca et al. | Endo-PDI is required for TNFα-induced angiogenesis | Free Radical Biology and Medicine | 2013 | ISSN 0891--5849 |
Chen, Bin et al. | Alteration of mevalonate pathway related enzyme expressions in pressure overload-induced cardiac hypertrophy and associated heart failure with preserved ejection fraction | Cellular Physiology and Biochemistry | 2013 | ISSN 1421-9778 |
Gil-Henn, H. et al. | Arg/Abl2 promotes invasion and attenuates proliferation of breast cancer in vivo | Oncogene | 2013 | ISSN 0950-9232 |