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Cytoskeleton Inc ECM Validation Data and Citations

ECM Product Citations

Fibronection Products

FNR01: Rhodamine Fibronectin

AuthorTitleJournalYearArticle Link
Lacroix, Mathilde et al.Emergence of bidirectional cell laning from collective contact guidanceNature Physics2024
Lo Vecchio, S. et al.Spontaneous rotations in epithelia as an interplay between cell polarity and boundariesNature Physics2024
Stinson, Matthew W. et al.Macrophage migration is differentially regulated by fibronectin and laminin through altered adhesion and myosin II localizationMolecular Biology of the Cell2024
Lichtenberg, Jessanne Y. et al.Leader cells mechanically respond to aligned collagen architecture to direct collective migrationPLOS ONE2024
Caillier, Alexia et al.T cells use focal adhesions to pull themselves through confined environmentsJournal of Cell Biology2024
Jana, Aniket et al.Mitotic outcomes and errors in fibrous environmentsProceedings of the National Academy of Sciences2023
Graybill, Philip M. et al.Ultra-thin and ultra-porous nanofiber networks as a basement-membrane mimicLab on a Chip2023
Sakai, Koji et al.Small-artery-mimicking multi-layered 3D co-culture in a self-folding porous graphene-based filmNanoscale Horizons2023
Mukherjee, Apratim et al.Actin Filaments Couple the Protrusive Tips to the Nucleus through the I-BAR Domain Protein IRSp53 during the Migration of Cells on 1D FibersAdvanced Science2023
Comelles, Jordi et al.Soft topographical patterns trigger a stiffness-dependent cellular response to contact guidanceMaterials Today Bio2023
Sadhu, Raj Kumar et al.Experimental and theoretical model for the origin of coiling of cellular protrusions around fibersNature Communications2023
Gibson, Shayin V. et al.ADAMTS3 restricts cancer invasion in models of early breast cancer progression through enhanced fibronectin degradationMatrix Biology2023
Dickinson, Richard B. et al.Viscous shaping of the compliant cell nucleusAPL Bioengineering2022
Van Der Putten, Cas et al.Protein Micropatterning in 2.5D: An Approach to Investigate Cellular Responses in Multi-Cue EnvironmentsACS Applied Materials and Interfaces2021
Lauko, Domokos I. et al.Baculovirus actin-rearrangement-inducing factor arif-1 induces the formation of dynamic invadosome clustersMolecular Biology of the Cell2021
Naka, Y. et al.Wholly vascularized millimeter-sized engineered tissues by cell-sized microscaffoldsMaterials Today Bio2020
Summerbell, Emily R. et al.Epigenetically heterogeneous tumor cells direct collective invasion through filopodia-driven fibronectin micropatterningScience Advances2020
Sundararaman, Ananthalakshmy et al.RhoJ Regulates α5β1 Integrin Trafficking to Control Fibronectin Remodeling during AngiogenesisCurrent Biology2020
Lo Vecchio, Simon et al.Collective Dynamics of Focal Adhesions Regulate Direction of Cell MotionCell Systems2020
Garbett, Damien et al.T-Plastin reinforces membrane protrusions to bridge matrix gaps during cell migrationNature Communications2020
Roveimiab, Ziba et al.Traction and attraction: Haptotaxis substrates collagen and fibronectin interact with chemotaxis by HGF to regulate myoblast migration in a microfluidic deviceAmerican Journal of Physiology - Cell Physiology2020
Horvath, Aron N. et al.The Protein Mat(ters) - Revealing the Biologically Relevant Mechanical Contribution of Collagen- And Fibronectin-Coated MicropatternsACS Applied Materials and Interfaces2019
Tomba, Caterina et al.Laser-Assisted Strain Engineering of Thin Elastomer Films to Form Variable Wavy Substrates for Cell CultureSmall2019
Rafiq, Nisha Bte Mohd et al.A mechano-signalling network linking microtubules, myosin IIA filaments and integrin-based adhesionsNature Materials2019
De Vos, Ivo J.H.M. et al.Functional analysis of a hypomorphic allele shows that MMP14 catalytic activity is the prime determinant of the Winchester syndrome phenotypeHuman Molecular Genetics2018
Hasan, Muhammad M. et al.Invadosome-mediated human extracellular matrix degradation by Entamoeba histolyticaInfection and Immunity2018
Varadaraj, Archana et al.TGF-β triggers rapid fibrillogenesis via a novel TβRII-dependent fibronectin-trafficking mechanismMolecular Biology of the Cell2017
Funano, Shun Ichi et al.Vapor-based micro/nano-partitioning of fluoro-functional group immobilization for long-term stable cell patterningRSC Advances2016
Mana, Giulia et al.PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesisNature Communications2016
Blehm, Benjamin H. et al.Deconstructing the role of the ECM microenvironment on drug efficacy targeting MAPK signaling in a pre-clinical platform for cutaneous melanomaBiomaterials2015
Wood, SheilaDifferentiation of Borrelia Microbes from Collagen Debris and Collagen Fibrils in Blood CulturesJournal of Microbiology & Experimentation2015
Comelles, Jordi et al.Cells as Active Particles in Asymmetric Potentials: Motility under External GradientsBiophysical Journal2014
Steele, Amanda N. et al.Tandem zyxin LIM sequences do not enhance force sensitive accumulationBiochemical and Biophysical Research Communications2012
Nakayama, Masamichi et al.Thermoresponsive poly(N-isopropylacrylamide)-based block copolymer coating for optimizing cell sheet fabricationMacromolecular bioscience2012
Nagase, Kenichi et al.Thermo-responsive polymer brushes as intelligent biointerfaces: preparation via ATRP and characterizationMacromolecular bioscience2011
Steward, Robert L. et al.Mechanical stretch and shear flow induced reorganization and recruitment of fibronectin in fibroblastsScientific Reports2011
Robinson, Elizabeth E. et al.Fibronectin Matrix Assembly Regulates α5β1-mediated Cell CohesionMolecular Biology of the Cell2004
Brock, Amy et al.Geometric Determinants of Directional Cell Motility Revealed Using Microcontact Printing†Langmuir2003

FNR02: Green Fluorescent Fibronectin

AuthorTitleJournalYearArticle Link
Islam, Md Mydul et al.Single-pericyte nanomechanics measured by contraction cytometryAPL Bioengineering2024
Sewid, Alaa H. et al.Distinguishing characteristics of Staphylococcus schleiferi and Staphylococcus coagulans of human and canine originPLOS ONE2024
Bittenbinder, Mátyás A. et al.Monitoring Snake Venom-Induced Extracellular Matrix Degradation and Identifying Proteolytically Active Venom Toxins Using Fluorescently Labeled SubstratesBiology2023
Xia, Qiaoxi et al.A protein complex of LCN2, LOXL2 and MMP9 facilitates tumour metastasis in oesophageal cancerMolecular Oncology2023
Baschieri, Francesco et al.Fibroblasts generate topographical cues that steer cancer cell migrationScience Advances2023
Han, Zuoning et al.Integrin aVβ1 regulates procollagen i production through a non-canonical transforming growth factor β signaling pathway in human hepatic stellate cellsBiochemical Journal2021
Pal, Kaushik et al.Ubiquitous membrane-bound DNase activity in podosomes and invadopodiaJournal of Cell Biology2021
Li, Wenhong et al.Differential cellular responses to adhesive interactions with galectin-8- And fibronectin-coated substratesJournal of Cell Science2021
Rong, Zhouyi et al.Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aβ42 in triggering receptor expressed on myeloid cells 2 loss-of-function murine modelsFASEB Journal2020
Huang, Yuxing et al.Arp2/3-branched actin maintains an active pool of GTP-RhoA and controls RhoA abundanceCells2019
Stanton, Alice E. et al.Biochemical Ligand Density Regulates Yes-Associated Protein Translocation in Stem Cells through Cytoskeletal Tension and IntegrinsACS Applied Materials and Interfaces2019
Foxall, Elizabeth et al.PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid CellsCell Reports2019
Sala, Laura et al.Abrogation of myofibroblast activities in metastasis and fibrosis by methyltransferase inhibitionInternational Journal of Cancer2019
Rafiq, Nisha Bte Mohd et al.Forces and constraints controlling podosome assembly and disassemblyPhilosophical Transactions of the Royal Society B: Biological Sciences2019
Sun, Xiaoyu et al.Replication of biocompatible, nanotopographic surfacesScientific Reports2018
Werley, Christopher A. et al.Geometry-dependent functional changes in iPSC-derived cardiomyocytes probed by functional imaging and RNA sequencingPLoS ONE2017
Kim, Jiyun et al.Three-dimensional patterning of the ECM microenvironment using magnetic nanoparticle self assemblyCurrent Protocols in Cell Biology2016
Kim, Jiyun et al.Independent Control of Topography for 3D Patterning of the ECM MicroenvironmentAdvanced Materials2016
Torr, Elizabeth E. et al.Myofibroblasts exhibit enhanced fibronectin assembly that is intrinsic to their contractile phenotypeJournal of Biological Chemistry2015
Stanisavljevic, Jelena et al.Snail1-expressing fibroblasts in the tumor microenvironment display mechanical properties that support metastasisCancer Research2015
Lively, Starlee et al.The microglial activation state regulates migration and roles of matrix-dissolving enzymes for invasionJournal of Neuroinflammation2013
Jacob, Abitha et al.Rab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cellsJournal of cell science2013

FNR03: Biotinylated Fibronectin

AuthorTitleJournalYearArticle Link
Wu, Maddalena Alessandra et al.Unlocking endothelial barrier restoration: FX06 in systemic capillary leak syndrome and beyondBiomedicine & Pharmacotherapy2024
Fedele, Giorgia et al.The Effects of Sirolimus and Magnesium on Primary Human Coronary Endothelial Cells: An In Vitro StudyInternational Journal of Molecular Sciences2023
Phillips, Andrew T. et al.USP10 promotes fibronectin recycling, secretion, and organizationInvestigative Ophthalmology and Visual Science2021
Varadaraj, Archana et al.Deoxycholate Fractionation of Fibronectin (FN) and Biotinylation Assay to Measure Recycled FN Fibrils in Epithelial CellsBio-Protocol2018
Varadaraj, Archana et al.TGF-β triggers rapid fibrillogenesis via a novel TβRII-dependent fibronectin-trafficking mechanismMolecular Biology of the Cell2017
Wang, Qiang et al.The human blood parasite Schistosoma mansoni expresses extracellular tegumental calpains that cleave the blood clotting protein fibronectinScientific Reports2017
Rodriguez, Natalia M. et al.Micropatterned multicolor dynamically adhesive substrates to control cell adhesion and multicellular organizationLangmuir2014

Laminin Products

LMN01: Rhodamine Laminin

AuthorTitleJournalYearArticle Link
Bittenbinder, Mátyás A. et al.Monitoring Snake Venom-Induced Extracellular Matrix Degradation and Identifying Proteolytically Active Venom Toxins Using Fluorescently Labeled SubstratesBiology2023
Kechagia, Zanetta et al.The laminin–keratin link shields the nucleus from mechanical deformation and signallingNature Materials2023
Frenzel, Jan et al.Laminin Adsorption and Adhesion of Neurons and Glial Cells on Carbon Implanted Titania Nanotube Scaffolds for Neural Implant ApplicationsNanomaterials2022
Coelho-Sampaio, Tatiana et al.Type IV collagen conforms to the organization of polylaminin adsorbed on planar substrataActa Biomaterialia2020
Zeng, Jinfeng et al.In Situ Cross-Linking of Artificial Basement Membranes in 3D Tissues and Their Size-Dependent Molecular PermeabilityBiomacromolecules2020
Fiore, Vincent F. et al.Mechanics of a multilayer epithelium instruct tumour architecture and functionNature2020
Zeng, Jinfeng et al.Fabrication of Artificial Nanobasement Membranes for Cell Compartmentalization in 3D TissuesSmall2020
Maechler, Florian A. et al.Curvature-dependent constraints drive remodeling of epitheliaJournal of Cell Science2019
Melero, Cristina et al.Light-induced molecular adsorption of proteins using the primo system for micro-patterning to study cell responses to extracellular matrix proteinsJournal of Visualized Experiments2019
Alessandri, Kevin et al.A 3D printed microfluidic device for production of functionalized hydrogel microcapsules for culture and differentiation of human Neuronal Stem Cells (hNSC)Lab on a Chip2016
Lantoine, Joséphine et al.Matrix stiffness modulates formation and activity of neuronal networks of controlled architecturesBiomaterials2016
Kim, Jiyun et al.Three-dimensional patterning of the ECM microenvironment using magnetic nanoparticle self assemblyCurrent Protocols in Cell Biology2016
Kim, Jiyun et al.Independent Control of Topography for 3D Patterning of the ECM MicroenvironmentAdvanced Materials2016
Hinüber, C. et al.Hierarchically structured nerve guidance channels based on poly-3-hydroxybutyrate enhance oriented axonal outgrowthActa Biomaterialia2014

LMN02: Green Fluorescent Laminin

AuthorTitleJournalYearArticle Link
Islam, Md Mydul et al.Single-pericyte nanomechanics measured by contraction cytometryAPL Bioengineering2024
Stinson, Matthew W. et al.Macrophage migration is differentially regulated by fibronectin and laminin through altered adhesion and myosin II localizationMolecular Biology of the Cell2024
Mattiassi, Sabrina et al.The Combined Effects of Topography and Stiffness on Neuronal Differentiation and Maturation Using a Hydrogel PlatformCells2023
Coelho-Sampaio, Tatiana et al.Type IV collagen conforms to the organization of polylaminin adsorbed on planar substrataActa Biomaterialia2020

LMN03: Biotinylated Laminin

AuthorTitleJournalYearArticle Link
Kechagia, Zanetta et al.The laminin–keratin link shields the nucleus from mechanical deformation and signallingNature Materials2023
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