Cytoskeleton Inc Kit and Assay Validation Data and Citations

Kit Citations

AuthorTitleJournalYearArticle Link
Duan, Xudong et al.Essential role of the endocytic site-associated protein Ecm25 in stress-induced cell elongationCell Reports2021ISSN 2211-1247
Yan, Yanling et al.RTKN-1/rhotekin shields endosome-associated F-actin from disassembly to ensure endocytic recyclingJournal of Cell Biology2021ISSN 1540-8140
Lu, Yi Ju et al.Arabidopsis calcium-dependent protein kinase 3 regulates actin cytoskeleton organization and immunityNature Communications2020ISSN 2041-1723
Park, Jin Suk et al.Mechanical regulation of glycolysis via cytoskeleton architectureNature2020ISSN 1476-4687
Gabel, Marion et al.Phosphorylation cycling of Annexin A2 Tyr23 is critical for calcium-regulated exocytosis in neuroendocrine cellsBiochimica et Biophysica Acta - Molecular Cell Research2019ISSN 1879-2596
Afreen, Sana et al.Altered Cytoskeletal Composition and Delayed Neurite Elongation in tau45–230-Expressing Hippocampal NeuronsNeuroscience2019ISSN 1873-7544
Krueger, Daniel et al.Cross-linker–mediated regulation of actin network organization controls tissue morphogenesisJournal of Cell Biology2019ISSN 1540-8140
Mao, Bai Ping et al.CaMSAP2 is a microtubule minus-end targeting protein that regulates BTB dynamics through cytoskeletal organizationEndocrinology2019ISSN 1945-7170
Zhang, Min et al.Axonogenesis Is Coordinated by Neuron-Specific Alternative Splicing Programming and Splicing Regulator PTBP2Neuron2019ISSN 1097-4199
Wen, Qing et al.Actin nucleator Spire 1 is a regulator of ectoplasmic specialization in the testisCell Death and Disease2018ISSN 2041-4889
Bardai, Farah H. et al.A conserved cytoskeletal signaling cascade mediates neurotoxicity of FTDP-17 tau mutations in vivoJournal of Neuroscience2018ISSN 1529-2401
Kschonsak, Yvonne T. et al.Activated ezrin controls MISP levels to ensure correct NuMA polarization and spindle orientationJournal of Cell Science2018ISSN 1477-9137
Leelarasamee, Natthanon et al.The root-knot nematode effector MiPFN3 disrupts plant actin filaments and promotes parasitismPLoS Pathogens2018ISSN 1553-7374
Gong, Ting et al. PTRN ‐1/ CAMSAP promotes CYK ‐1/formin‐dependent actin polymerization during endocytic recycling The EMBO Journal2018ISSN 0261--4189
Shioda, Norifumi et al.Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome articleNature Medicine2018ISSN 1546-170X
Loukil, Abdelhalim et al.Foci of cyclin A2 interact with actin and RhoA in mitosisScientific Reports2016ISSN 2045-2322
Feng, Di et al.Functional validation of an alpha-actinin-4 mutation as a potential cause of an aggressive presentation of adolescent focal segmental glomerulosclerosis: Implications for genetic testingPLoS ONE2016ISSN 1932-6203
Gao, Ying et al.Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cellsScientific Reports2016ISSN 2045-2322
Wang, Peixiang et al.RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling EndosomesPLoS Genetics2016ISSN 1553-7404
Tie, S. R. et al.Regulation of sarcoma cell migration, invasion and invadopodia formation by AFAP1L1 through a phosphotyrosine-dependent pathwayOncogene2016ISSN 1476-5594
Li, Nan et al.Overexpression of plastin 3 in Sertoli cells disrupts actin microfilament bundle homeostasis and perturbs the tight junction barrierSpermatogenesis2016Article Link
Gabel, Marion et al.Annexin A2-dependent actin bundling promotes secretory granule docking to the plasma membrane and exocytosisJournal of Cell Biology2015ISSN 1540-8140
Li, Nan et al.Formin 1 regulates ectoplasmic specialization in the rat testis through its actin nucleation and bundling activityEndocrinology (United States)2015ISSN 1945-7170
Li, Nan et al.Actin-bundling protein plastin 3 is a regulator of ectoplasmic specialization dynamics during spermatogenesis in the rat testisFASEB Journal2015ISSN 1530-6860
Calvo, Fernando et al.Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated FibroblastsCell Reports2015ISSN 2211-1247
Lin, Wei Chi et al.Actin-binding protein G (AbpG) participates in modulating the actin cytoskeleton and cell migration in Dictyostelium discoideumMolecular Biology of the Cell2015ISSN 1939-4586
Delorme-Walker, Violaine et al.Chronophin coordinates cell leading edge dynamics by controlling active cofilin levelsProceedings of the National Academy of Sciences of the United States of America2015ISSN 1091-6490
Kang, Yongsung et al.HopW1 from Pseudomonas syringae Disrupts the Actin Cytoskeleton to Promote Virulence in ArabidopsisPLoS Pathogens2014ISSN 1553-7374
Clarke, Joseph P. et al.Cell Stress Promotes the Association of Phosphorylated HspB1 with F-ActinPLoS ONE2013ISSN 1932-6203
Zhu, Mei et al.MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progressionJournal of Cell Biology2013ISSN 0021-9525
Kitagawa, Mayumi et al.Targeting Aurora B to the Equatorial Cortex by MKlp2 Is Required for CytokinesisPLoS ONE2013ISSN 1932-6203
Wolter, Patrick et al.GAS2L3, a target gene of the DREAM complex, is required for proper cytokinesis and genomic stabilityJournal of cell science2012ISSN 1477--9137
Munsie, Lise Nicole et al.Cofilin nuclear-cytoplasmic shuttling affects cofilin-actin rod formation during stressJournal of Cell Science2012ISSN 0021-9533
Marat, Andrea L. et al.Connecdenn 3/DENND1C binds actin linking Rab35 activation to the actin cytoskeletonMolecular Biology of the Cell2012ISSN 1059-1524
Trulsson, Maria et al.HAMLET Binding to α-Actinin Facilitates Tumor Cell DetachmentPLOS ONE2011ISSN 1932--6203
Pang, Te Ling et al.Costars, a Dictyosteliumprotein similar to the C-terminal domain of STARS, regulates the actin cytoskeleton and motilityJournal of Cell Science2010ISSN 0021-9533
Davis, David A. et al.Capzb2 interacts with β-tubulin to regulate growth cone morphology and neurite outgrowthPLoS Biology2009ISSN 1544-9173
Gohla, Antje et al.Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamicsNature cell biology2005ISSN 1465--7392
Falcón-Pérez, Juan M. et al.BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granulesThe Journal of biological chemistry2002ISSN 0021--9258
Zhai, Liwei et al.Tyrosine phosphorylation of villin regulates the organization of the actin cytoskeletonThe Journal of biological chemistry2001ISSN 0021--9258
Leung, Conrad L. et al.Microtubule Actin Cross-Linking Factor (Macf)A Hybrid of Dystonin and Dystrophin That Can Interact with the Actin and Microtubule CytoskeletonsJournal of Cell Biology1999ISSN 0021--9525
AuthorTitleJournalYearArticle Link
Duan, Xudong et al.Essential role of the endocytic site-associated protein Ecm25 in stress-induced cell elongationCell Reports2021ISSN 2211-1247
Yasuda, Hidenori et al.Tacrolimus ameliorates podocyte injury by restoring FK506 binding protein 12 (FKBP12) at actin cytoskeletonThe FASEB Journal2021ISSN 1530--6860
Cousin, M A et al.Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndromeNature …2021Article Link
Lu, Yi Ju et al.Arabidopsis calcium-dependent protein kinase 3 regulates actin cytoskeleton organization and immunityNature Communications2020ISSN 2041-1723
Alburquerque-González, Begoña et al.New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cellsExperimental and Molecular Medicine2020ISSN 2092-6413
Afreen, Sana et al.Altered Cytoskeletal Composition and Delayed Neurite Elongation in tau 45-230-Expressing Hippocampal NeuronsNeuroscience2019ISSN 1873--7544
Wang, Guang et al.Rab7 regulates primary cilia disassembly through cilia excisionJournal of Cell Biology2019ISSN 1540-8140
Kumar, M. Nagaraj et al.Low water potential and AT14A-like1 (AFL1) effects on endocytosis and actin filament organizationPlant Physiology2019ISSN 1532-2548
Fu, Chuntang et al.JMJD3 regulates CD4+ T cell trafficking by targeting actin cytoskeleton regulatory gene Pdlim4Journal of Clinical Investigation2019ISSN 1558-8238
Balta, Emre et al.Spatial oxidation of L-plastin downmodulates actin-based functions of tumor cellsNature Communications2019ISSN 2041-1723
Laitila, Jenni et al.A nebulin super-repeat panel reveals stronger actin binding toward the ends of the super-repeat regionMuscle and Nerve2019ISSN 1097-4598
Wen, Qing et al.Actin nucleator Spire 1 is a regulator of ectoplasmic specialization in the testisCell Death and Disease2018ISSN 2041-4889
Bardai, Farah H. et al.A conserved cytoskeletal signaling cascade mediates neurotoxicity of FTDP-17 tau mutations in vivoJournal of Neuroscience2018ISSN 1529-2401
Schaffer, Ashleigh E. et al.Biallelic loss of human CTNNA2, encoding αN-catenin, leads to ARP2/3 complex overactivity and disordered cortical neuronal migrationNature Genetics2018ISSN 1546-1718
Da’as, Sahar I. et al.Hypertrophic cardiomyopathy-linked variants of cardiac myosin-binding protein C3 display altered molecular properties and actin interactionBiochemical Journal2018ISSN 1470-8728
Cervero, Pasquale et al.Lymphocyte-specific protein 1 regulates mechanosensory oscillation of podosomes and actin isoform-based actomyosin symmetry breakingNature Communications2018ISSN 2041-1723
Wu, Tongbin et al.HSPB7 is indispensable for heart development by modulating actin filament assemblyProceedings of the National Academy of Sciences of the United States of America2017ISSN 1091-6490
Guan, Liying et al.The Calponin Family Member CHDP-1 Interacts with Rac/CED-10 to Promote Cell ProtrusionsPLoS Genetics2016ISSN 1553-7404
Szeto, Sandy G.Y. et al.Phosphorylation of filamin A by Cdk1 regulates filamin A localization and daughter cell separationExperimental Cell Research2015ISSN 1090-2422
Yan, Yi et al.Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5Nature Communications2015ISSN 2041-1723
Kumeta, Masahiro et al.Caprice/MISP is a novel F-actin bundling protein critical for actin-based cytoskeletal reorganizationsGenes to Cells2014ISSN 1365-2443
Mokbel, Nancy et al.K7del is a common TPM2 gene mutation associated with nemaline myopathy and raised myofibre calcium sensitivityBrain2013ISSN 1460-2156
Wang, Tzu Fan et al.Identification and characterization of the actin-binding motif of PhostensinInternational Journal of Molecular Sciences2012ISSN 1422-0067
Lai, Ning Sheng et al.Phostensin caps to the pointed end of actin filaments and modulates actin dynamicsBiochemical and Biophysical Research Communications2009ISSN 0006-291X
Meira, Maria et al.Memo is a cofilin-interacting protein that influences PLCγ1 and cofilin activities, and is essential for maintaining directionality during ErbB2-induced tumor-cell migrationJournal of Cell Science2009ISSN 0021-9533
McCloskey, Diana T. et al.Hypotonic activation of short ClC3 isoform is modulated by direct interaction between its cytosolic C-terminal tail and subcortical actin filamentsJournal of Biological Chemistry2007ISSN 0021-9258
Takeshita, Norio et al.CsmA, a Class V Chitin Synthase with a Myosin Motor-like Domain, Is Localized through Direct Interaction with the Actin Cytoskeleton in Aspergillus nidulansMolecular Biology of the Cell2005ISSN 1059-1524
Terry-Lorenzo, Ryan T. et al.Neurabin/protein phosphatase-1 complex regulates dendritic spine morphogenesis and maturationMolecular Biology of the Cell2005ISSN 1059-1524
Torgler, Catherine N. et al.Tensin Stabilizes Integrin Adhesive Contacts in DrosophilaDevelopmental Cell2004ISSN 1534--5807
Kumar, Narendra et al.Association of villin with phosphatidylinositol 4,5-bisphosphate regulates the actin cytoskeletonThe Journal of biological chemistry2004ISSN 0021--9258
Banerjee, Jayashree et al.Identification of a Novel Sequence in PDZ-RhoGEF That Mediates Interaction with the Actin CytoskeletonMolecular Biology of the Cell2004ISSN 1059-1524
Goryunov, Dmitry et al.Studying cytolinker proteinsMethods in Cell Biology2004ISSN 0091-679X
Oliver, Carey J. et al.Targeting Protein Phosphatase 1 (PP1) to the Actin Cytoskeleton: the Neurabin I/PP1 Complex Regulates Cell MorphologyMolecular and Cellular Biology2002ISSN 0270--7306
Hildebrand, Jeffrey D. et al.Shroom, a PDZ Domain–Containing Actin-Binding Protein, Is Required for Neural Tube Morphogenesis in MiceCell1999ISSN 0092--8674
AuthorTitleJournalYearArticle Link
Bogucka-Janczi, Katarzyna et al.ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization.eLife2023ISSN 2050--084X
Ángeles-Robles, Gabriela et al.Actin protein inside DMPC GUVs and its mechanical response to AC electric fieldsBiochimica et Biophysica Acta (BBA) - Biomembranes2022
Geng, Mengxin et al.Synthesis and characterization of semisynthetic analogs of the antifungal occidiofunginFrontiers in Microbiology2022
Chen, Binghong et al.Cleavage of tropomodulin-3 by asparagine endopeptidase promotes cancer malignancy by actin remodeling and SND1/RhoA signalingJournal of Experimental and Clinical Cancer Research2022ISSN 1756-9966
Wang, Baolei et al.Numb and Numblike regulate sarcomere assembly and maintenanceJournal of Clinical Investigation2022ISSN 1558-8238
Hsiao, Bo Yuan et al.Human costars family protein abracl modulates actin dynamics and cell migration and associates with tumorigenic growthInternational Journal of Molecular Sciences2021ISSN 1422-0067
Misra, Suniti et al.Periostin/Filamin-A: A Candidate Central Regulatory Axis for Valve Fibrogenesis and Matrix CompactionFrontiers in Cell and Developmental Biology2021ISSN 2296-634X
Bock, Fabian et al.Rac1 promotes kidney collecting duct integrity by limiting actomyosin activityJournal of Cell Biology2021ISSN 1540-8140
Yan, Yanling et al.RTKN-1/rhotekin shields endosome-associated F-actin from disassembly to ensure endocytic recyclingJournal of Cell Biology2021ISSN 1540-8140
Sarkar, Souvarish et al.Oligomerization of Lrrk controls actin severing and α-synuclein neurotoxicity in vivoMolecular Neurodegeneration2021ISSN 1750-1326
Shimura, Daisuke et al.Protective mitochondrial fission induced by stress-responsive protein GJA1-20keLife2021ISSN 2050-084X
Chen, Yuewen et al.Coronin 2B regulates dendrite outgrowth by modulating actin dynamicsFEBS Letters2020ISSN 1873-3468
Kang, Dong Hee et al.Down-regulation of diesel particulate matter-induced airway inflammation by the PDZ motif peptide of ZO-1Journal of Cellular and Molecular Medicine2020ISSN 1582-1838
Lamm, Noa et al.Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stressNature Cell Biology2020ISSN 1476-4679
Schneidewind, Tabea et al.The Pseudo Natural Product Myokinasib Is a Myosin Light Chain Kinase 1 Inhibitor with Unprecedented ChemotypeCell Chemical Biology2019ISSN 2451-9448
Limatola, Nunzia et al.Nicotine Induces Polyspermy in Sea Urchin Eggs through a Non-Cholinergic Pathway Modulating Actin DynamicsCells2019ISSN 2073-4409
Li, Linxi et al.Planar cell polarity protein Dishevelled 3 (Dvl3) regulates ectoplasmic specialization (ES) dynamics in the testis through changes in cytoskeletal organizationCell Death and Disease2019ISSN 2041-4889
Liu, Juan et al.CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated GlycolysisImmunity2019ISSN 1097-4180
Li, Lin Xi et al.Regulation of blood-testis barrier dynamics by the mTORC1/rpS6 signaling complex: An in vitro studyAsian Journal of Andrology2019ISSN 1745-7262
Lang, Lei et al.ATM-Mediated phosphorylation of cortactin involved in actin polymerization promotes breast cancer cells migration and invasionCellular Physiology and Biochemistry2019ISSN 1421-9778
Zhang, Min et al.Axonogenesis Is Coordinated by Neuron-Specific Alternative Splicing Programming and Splicing Regulator PTBP2Neuron2019ISSN 1097-4199
Ravichandran, Akshaya et al.A novel actin binding drug with in vivo efficacyAntimicrobial Agents and Chemotherapy2019ISSN 1098-6596
Kommaddi, Reddy Peera et al.Aβ mediates F-actin disassembly in dendritic spines leading to cognitive deficits in alzheimer’s diseaseJournal of Neuroscience2018ISSN 1529-2401
Wen, Qing et al.Actin nucleator Spire 1 is a regulator of ectoplasmic specialization in the testisCell Death and Disease2018ISSN 2041-4889
Bardai, Farah H. et al.Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamicsPLoS Biology2018ISSN 1545-7885
Gau, David et al.Structure-based virtual screening identifies a small-molecule inhibitor of the profilin 1–actin interactionJournal of Biological Chemistry2018ISSN 1083-351X
Shioda, Norifumi et al.Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome articleNature Medicine2018ISSN 1546-170X
Kim, Mi Seon et al.Src is the primary target of aripiprazole, an atypical antipsychotic drug, in its anti-tumor actionOncotarget2018ISSN 1949-2553
Patel, Vaibhav B. et al.PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart diseaseNature Communications2018ISSN 2041-1723
Kumar, Dhivya et al.Microvillar and ciliary defects in zebrafish lacking an actin-binding bioactive peptide amidating enzymeScientific Reports2018ISSN 2045-2322
Sarowar, Tasnuva et al.Object phobia and altered RhoA signaling in amygdala of mice lacking RICH2Frontiers in Molecular Neuroscience2017ISSN 1662-5099
Misiak, Majus et al.Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7Oncotarget2017ISSN 1949-2553
Tormos, Ana M. et al.P38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and agingPLoS ONE2017ISSN 1932-6203
Wu, Tongbin et al.HSPB7 is indispensable for heart development by modulating actin filament assemblyProceedings of the National Academy of Sciences of the United States of America2017ISSN 1091-6490
Kumar, Raj et al.A new role for cofilin in retinal neovascularizationJournal of Cell Science2016ISSN 1477-9137
Sarowar, Tasnuva et al.Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2Molecular Brain2016ISSN 1756-6606
Kpetemey, Marilyne et al.MIEN1 drives breast tumor cell migration by regulating cytoskeletal-focal adhesion dynamicsOncotarget2016ISSN 1949-2553
Rondina, M. T. et al.Non-genomic activities of retinoic acid receptor alpha control actin cytoskeletal events in human plateletsJournal of Thrombosis and Haemostasis2016ISSN 1538-7836
Chakraborty, Sayan et al.An oncogenic role of Agrin in regulating focal adhesion integrity in hepatocellular carcinomaNature Communications2015ISSN 2041-1723
Jiang, Shiyou et al.A group of ent-Kaurane diterpenoids inhibit hedgehog signaling and induce cilia elongationPLoS ONE2015ISSN 1932-6203
Henkels, Karen M. et al.S6K is a morphogenic protein with a mechanism involving Filamin-A phosphorylation and phosphatidic acid bindingFASEB Journal2015ISSN 1530-6860
Lin, Wei Chi et al.Actin-binding protein G (AbpG) participates in modulating the actin cytoskeleton and cell migration in Dictyostelium discoideumMolecular Biology of the Cell2015ISSN 1939-4586
Odermatt, Pascal D. et al.High-Resolution Correlative Microscopy: Bridging the Gap between Single Molecule Localization Microscopy and Atomic Force MicroscopyNano Letters2015ISSN 1530-6992
Lutz, Vanessa et al.SAR studies on hydropentalene derivatives - Important core units of biologically active tetramic acid macrolactams and ptychanolidesBioorganic and Medicinal Chemistry2014ISSN 1464-3391
Chan, Eddie et al.The acetylenic tricyclic bis(cyano enone), TBE-31 inhibits non-small cell lung cancer cell migration through direct binding with actinCancer Prevention Research2014ISSN 1940-6215
Speranza, Francis et al.The molecular basis of leukocyte adhesion involving phosphatidic acid and phospholipase DJournal of Biological Chemistry2014ISSN 1083-351X
La Clair, James J. et al.In Situ natural product discovery via an artificial marine spongePLoS ONE2014ISSN 1932-6203
Nievergelt, Adrian P. et al.High-frequency multimodal atomic force microscopyBeilstein Journal of Nanotechnology2014ISSN 2190-4286
Yuan, Baiyin et al.A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in miceAmerican Journal of Pathology2014ISSN 1525-2191
Taniuchi, Keisuke et al.RUVBL1 directly binds actin filaments and induces formation of cell protrusions to promote pancreatic cancer cell invasionInternational Journal of Oncology2014ISSN 1791-2423
Xiao, Xiang et al.c-Yes regulates cell adhesion at the apical ectoplasmic specialization-blood-testis barrier axis via its effects on protein recruitment and distribution2013PMID 23169788
Jiwani, Shahanawaz et al.Chlamydia trachomatis Tarp cooperates with the Arp2/3 complex to increase the rate of actin polymerizationBiochemical and Biophysical Research Communications2012ISSN 0006-291X
Fan, Jianguo et al.A role for γs-crystallin in the organization of actin and fiber cell maturation in the mouse lensFEBS Journal2012ISSN 1742-464X
Butler, Suzanne C. et al.Inhibitory effects of pectenotoxins from marine algae on the polymerization of various actin isoformsToxicology in Vitro2012ISSN 0887-2333
Perisic, Ljubica et al.Plekhh2, a novel podocyte protein downregulated in human focal segmental glomerulosclerosis, is involved in matrix adhesion and actin dynamicsKidney International2012ISSN 1523-1755
Xavier, Charles Peter et al.Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migrationScientific Reports2012ISSN 2045-2322
Trigili, Chiara et al.Mechanism of Action of the Cytotoxic Macrolides Amphidinolide X and JChemBioChem2011ISSN 1439-4227
Tsai, Chih Chien et al.7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel ROCK inhibitor blocks cytoskeleton function and cell migrationBiochemical Pharmacology2011ISSN 0006-2952
Peterson, Jon E. et al.Normal ranges of angiogenesis regulatory proteins in human plateletsAmerican Journal of Hematology2010ISSN 0361-8609
Lai, Ning Sheng et al.Phostensin caps to the pointed end of actin filaments and modulates actin dynamicsBiochemical and Biophysical Research Communications2009ISSN 0006-291X
Chellaiah, Meenakshi A. et al.Phosphorylation of a Wiscott-Aldrich syndrome protein-associated signal complex is critical in osteoclast bone resorptionJournal of Biological Chemistry2007ISSN 0021-9258
Nusco, Gilda A. et al.Modulation of calcium signalling by the actin-binding protein cofilinBiochemical and Biophysical Research Communications2006ISSN 0006-291X
Takamiya, Rina et al.Overexpression of mutated Cu,Zn-SOD in neuroblastoma cells results in cytoskeletal changeAmerican journal of physiology. Cell physiology2005ISSN 0363--6143
Chellaiah, Meenakshi A.Regulation of actin ring formation by Rho GTPases in osteoclastsJournal of Biological Chemistry2005ISSN 0021-9258
Kumar, Narendra et al.Functional dissection and molecular characterization of calcium-sensitive actin-capping and actin-depolymerizing sites in villinThe Journal of biological chemistry2004ISSN 0021--9258
Nielsen, Finn C. et al.Cytoplasmic trafficking of IGF-II mRNA-binding protein by conserved KH domainsJournal of Cell Science2002ISSN 0021-9533
Zhai, Liwei et al.Tyrosine phosphorylation of villin regulates the organization of the actin cytoskeletonThe Journal of biological chemistry2001ISSN 0021--9258
Fontao, Lionel et al.The interaction of plectin with actin: evidence for cross-linking of actin filaments by dimerization of the actin-binding domain of plectinJournal of cell science2001ISSN 0021--9533
Blader, Ira J. et al.GCS1, an Arf guanosine triphosphatase-activating protein in Saccharomyces cerevisiae, is required for normal actin cytoskeletal organization in vivo and stimulates actin polymerization in vitroMolecular Biology of the Cell1999ISSN 1059-1524
AuthorTitleJournalYearArticle Link
Daso, Rachel E. et al.Self-Assembled Peptide-Based Biocomposites for Near-Infrared Light Triggered Drug Release to Tumor CellsBiotechnology Journal2020ISSN 1860--7314
Lucas, Erin D. et al.PD-L1 Reverse Signaling in Dermal Dendritic Cells Promotes Dendritic Cell Migration Required for Skin ImmunityCell Reports2020ISSN 2211-1247
Choi, Seungho et al.Asymmetric dimethylarginine exacerbates cognitive dysfunction associated with cerebrovascular pathologyFASEB Journal2020ISSN 1530-6860
Verboon, Jeffrey M. et al.Infantile Myelofibrosis and Myeloproliferation with CDC42 DysfunctionJournal of Clinical Immunology2020ISSN 1573-2592
Choi, Seungho et al.Regulation of endothelial barrier integrity by redox-dependent nitric oxide signaling: Implication in traumatic and inflammatory brain injuriesNitric Oxide - Biology and Chemistry2019ISSN 1089-8611
Gao, Chong et al.Context-dependent roles of MDMX (MDM4) and MDM2 in breast cancer proliferation and circulating tumor cellsBreast Cancer Research2019ISSN 1465-542X
Hu, Ruixi et al.RNA-binding protein PUM2 suppresses osteosarcoma progression via partly and competitively binding to STARD13 3′UTR with miRNAsCell Proliferation2018ISSN 1365-2184
Gao, Fei et al.STARD13 is positively correlated with good prognosis and enhances 5-FU sensitivity via suppressing cancer stemness in hepatocellular carcinoma cellsOncoTargets and Therapy2018ISSN 1178-6930
Kundu, Nandini et al.Estrogen-activated MDM2 disrupts mammary tissue architecture through a p53-independent pathwayOncotarget2017ISSN 1949-2553
Jenkins, Edmund C. et al.Na+/H+ exchanger 1 (NHE1) function is necessary for maintaining mammary tissue architectureDevelopmental Dynamics2014ISSN 1058-8388
Asahara, S. et al.Ras-related C3 botulinum toxin substrate 1 (RAC1) regulates glucose-stimulated insulin secretion via modulation of F-actinDiabetologia2013PMID 23412604
Arita, Ryoichi et al.A key role for ROCK in TNF-α-mediated diabetic microvascular damageInvestigative Ophthalmology and Visual Science2013ISSN 0146-0404
Valtcheva, Nadejda et al.The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42Journal of Biological Chemistry2013ISSN 0021-9258
Ren, Wen Wen et al.Stimulation of α2A-adrenoceptors promotes the maturation of dendritic spines in cultured neurons of the medial prefrontal cortexMolecular and Cellular Neuroscience2012ISSN 1044--7431
Spangler, Barbara et al.ETS-1/RhoC signaling regulates the transcription factor c-Jun in melanomaInternational Journal of Cancer2012ISSN 1097--0215
Haidari, Mehran et al.Inhibition of MLC phosphorylation restricts replication of influenza virus-a mechanism of action for anti-influenza agentsPLoS ONE2011ISSN 1932-6203
Isik, Nilgun et al.An Elmo-like Protein Associated with Myosin II Restricts Spurious F-Actin Events to Coordinate Phagocytosis and ChemotaxisDevelopmental Cell2008ISSN 1534-5807
AuthorTitleJournalYearArticle Link
Wu, Qiaoyun et al.Electroacupuncture inhibits dendritic spine remodeling through the srGAP3-Rac1 signaling pathway in rats with SNLBiological Research2023ISSN 0717-6287
Wang, Caiqin et al.Induction of filopodia formation by α-Actinin-2 via RelA with a feedforward activation loop promoting overt bone marrow metastasis of gastric cancerJournal of Translational Medicine 2023 21:12023ISSN 1479--5876
Correa, Francisco et al.Actin-Cytoskeleton Drives Caveolae Signaling to Mitochondria during PostconditioningCells2023ISSN 2073-4409
Bogucka-Janczi, Katarzyna et al.ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization.eLife2023ISSN 2050--084X
Li, Linxi et al.PCP Protein Inversin Regulates Testis Function Through Changes in Cytoskeletal Organization of Actin and MicrotubulesEndocrinology2022ISSN 0013--7227
Si, Hongjiang et al.A Highlights from MBoC Selection: Noncanonical Wnt/Ror2 signaling regulates cell–matrix adhesion to prompt directional tumor cell invasion in breast cancerMolecular Biology of the Cell2022ISSN 1939-4586
Flores-Muñoz, Carolina et al.The Long-Term Pannexin 1 Ablation Produces Structural and Functional Modifications in Hippocampal NeuronsCells2022ISSN 2073-4409
Lohraseb, Iman et al.Global ubiquitinome profiling identifies NEDD4 as a regulator of Profilin 1 and actin remodelling in neural crest cellsNature Communications 2022 13:12022ISSN 2041--1723
Fang, Shi et al.RhoBTB1 reverses established arterial stiffness in angiotensin II–induced hypertension by promoting actin depolymerizationJCI Insight2022ISSN 0021--9738
He, Zheng Quan et al.Pharmacological regulation of tissue fibrosis by targeting the mechanical contraction of myofibroblastsFundamental Research2022ISSN 2667-3258
Zhang, Yan et al.Different changes in pre- and postsynaptic components in the hippocampal CA1 subfield after transient global cerebral ischemiaBrain Structure and Function2022ISSN 1863-2661
Garcia, Alix et al.miR-204-5p and Platelet Function Regulation: Insight into a Mechanism Mediated by CDC42 and GPIIbIIIaThrombosis and haemostasis2021ISSN 2567--689X
Misra, Suniti et al.Periostin/Filamin-A: A Candidate Central Regulatory Axis for Valve Fibrogenesis and Matrix CompactionFrontiers in Cell and Developmental Biology2021ISSN 2296-634X
Saal, Kim Ann et al.Rho-kinase inhibition by fasudil modulates pre-synaptic vesicle dynamicsJournal of Neurochemistry2021ISSN 1471--4159
Balbi, Carolina et al.An exosomal-carried short periostin isoform induces cardiomyocyte proliferationTheranostics2021ISSN 1838--7640
Zhang, Chong et al.Fibrinogen/AKT/Microfilament Axis Promotes Colitis by Enhancing Vascular PermeabilityCellular and molecular gastroenterology and hepatology2021ISSN 2352--345X
Gupta, Richa et al.Ectopic expression of 35 kDa and knocking down of 78 kDa SG2NAs induce cytoskeletal reorganization, alter membrane sialylation, and modulate the markers of EMTMolecular and cellular biochemistry2021ISSN 1573--4919
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Kanazawa, Yasushi et al.The Rho-kinase inhibitor fasudil restores normal motor nerve conduction velocity in diabetic rats by assuring the proper localization of adhesion-related molecules in myelinating Schwann cellsExperimental neurology2013ISSN 1090--2430
DiScipio, Richard G. et al.Complement C3a signaling mediates production of angiogenic factors in mesenchymal stem cellsJournal of Biomedical Science and Engineering2013ISSN 1937--6871
Chen, Guang et al.Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells (Journal of Biological Chemistry (2012) 2Journal of Biological Chemistry2012ISSN 0021-9258
Greco, Carolina M. et al.Chemotactic effect of prorenin on human aortic smooth muscle cells: a novel function of the (pro)renin receptorCardiovascular Research2012ISSN 0008--6363
Dhaliwal, Anandika et al.Cellular Cytoskeleton Dynamics Modulates Non-Viral Gene Delivery through RhoGTPases2012PMID 22509380
Ramsay, Alan G. et al.Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenali******: Establishing a reversible immune evasion mechanism in human cancerBlood2012ISSN 1528-0020
Chen, Si Meng et al.Inhibition of tumor cell growth, proliferation and migration by X-387, a novel active-site inhibitor of mTORBiochemical Pharmacology2012ISSN 0006-2952
Howe, Grant A. et al.RhoB controls endothelial cell morphogenesis in part via negative regulation of RhoAVascular Cell2012ISSN 2045--824X
Yang, Seungwon et al.The RhoA-ROCK-PTEN pathway as a molecular switch for anchorage dependent cell behaviorBiomaterials2012ISSN 1878--5905
Garrido‐Gómez, Tamara et al.Annexin A2 is critical for embryo adhesiveness to the human endometrium by RhoA activation through F‐actin regulationThe FASEB Journal2012ISSN 0892--6638
Zhou, Zhigang et al.HSV-mediated gene transfer of C3 transferase inhibits Rho to promote axonal regenerationExperimental Neurology2012ISSN 0014--4886
McCoy, Kelly L. et al.Protease-activated receptor 1 (PAR1) coupling to G(q/11) but not to G(i/o) or G(12/13) is mediated by discrete amino acids within the receptor second intracellular loopCellular signalling2012ISSN 1873--3913
Ramseyer, Vanesa D. et al.Tumor necrosis factor α decreases nitric oxide synthase type 3 expression primarily via Rho/Rho kinase in the thick ascending limbHypertension (Dallas, Tex. : 1979)2012ISSN 1524--4563
Takefuji, Mikito et al.G13-mediated signaling pathway is required for pressure overload-induced cardiac remodeling and heart failureCirculation2012ISSN 0009-7322
Jin, Wanzhu et al.Increased SRF transcriptional activity in human and mouse skeletal muscle is a signature of insulin resistanceJournal of Clinical Investigation2011ISSN 0021-9738
Aguilar, Hector N. et al.Phos-tag-based analysis of myosin regulatory light chain phosphorylation in human uterine myocytesPLoS ONE2011ISSN 1932-6203
Ganguly, Riya et al.Adiponectin Increases LPL Activity via RhoA/ROCK-Mediated Actin Remodelling in Adult Rat CardiomyocytesEndocrinology2011ISSN 0013--7227
Musso, Alessandra et al.Relevance of the mevalonate biosynthetic pathway in the regulation of bone marrow mesenchymal stromal cell-mediated effects on T-cell proliferation and B-cell survivalHaematologica2011ISSN 1592--8721
Lichtenstein, Mathieu P. et al.Secretase-independent and RhoGTPase/PAK/ERK-dependent regulation of cytoskeleton dynamics in astrocytes by NSAIDs and derivativesJournal of Alzheimer's disease : JAD2010ISSN 1875--8908
Ridgway, Lon D. et al.Modulation of GEF-H1 Induced Signaling by Heparanase in Brain Metastatic Melanoma CellsJournal of cellular biochemistry2010ISSN 0730-2312
Rapier, Rebecca et al.The extracellular matrix microtopography drives critical changes in cellular motility and Rho A activity in colon cancer cellsCancer Cell International2010ISSN 1475-2867
Romero, Ana M. et al.Chronic ethanol exposure alters the levels, assembly, and cellular organization of the actin cytoskeleton and microtubules in hippocampal neurons in primary cultureToxicological Sciences2010ISSN 1096-6080
Nini, Lylia et al.Accurate and reproducible measurements of RhoA activation in small samples of primary cellsAnalytical biochemistry2010ISSN 1096--0309
Yang, Enyue et al.Fluoride induces vascular contraction through activation of RhoA/Rho kinase pathway in isolated rat aortasEnvironmental toxicology and pharmacology2010ISSN 1872--7077
Hammar, Eva et al.Role of the Rho-ROCK (Rho-Associated Kinase) Signaling Pathway in the Regulation of Pancreatic β-Cell FunctionEndocrinology2009ISSN 0013--7227
Chastre, Eric et al.TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasivenessThe FASEB Journal2009ISSN 1530--6860
Seifert, Jennifer L. et al.Differential activation of Rac1 and RhoA in neuroblastoma cell fractionsNeuroscience letters2009ISSN 0304--3940
Ramirez, Servio H. et al.Activation of Peroxisome Proliferator-Activated Receptor γ (PPARγ) Suppresses Rho GTPases in Human Brain Microvascular Endothelial Cells and Inhibits Adhesion and Transendothelial Migration of HIV-1 Infected MonocytesThe Journal of Immunology2008ISSN 0022--1767
Kinoshita, Nagatoki et al.Apical Accumulation of Rho in the Neural Plate Is Important for Neural Plate Cell Shape Change and Neural Tube FormationMolecular Biology of the Cell2008ISSN 1059-1524
Mercer, Jason et al.Vaccinia virus uses macropinocytosis and apoptotic mimicry to enter host cellsScience (New York, N.Y.)2008ISSN 1095--9203
Sequeira, Linda et al.Rho GTPases in PC-3 prostate cancer cell morphology, invasion and tumor cell diapedesisClinical & experimental metastasis2008ISSN 0262--0898
Moore, Simon W. et al.Rho inhibition recruits DCC to the neuronal plasma membrane and enhances axon chemoattraction to netrin 1Development2008ISSN 0950--1991
Korobova, Farida et al.Arp2/3 complex is important for filopodia formation, growth cone motility, and neuritogenesis in neuronal cellsMolecular biology of the cell2008ISSN 1939--4586
Tanaka, Shigeru et al.Neural expression of G protein-coupled receptors GPR3, GPR6, and GPR12 up-regulates cyclic AMP levels and promotes neurite outgrowthThe Journal of biological chemistry2007ISSN 0021--9258
Schreibelt, Gerty et al.Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signalingFASEB journal : official publication of the Federation of American Societies for Experimental Biology2007ISSN 1530--6860
Keely, Patricia J. et al.Investigating integrin regulation and signaling events in three-dimensional systemsMethods in enzymology2007ISSN 0076--6879
Rupp, Paul A. et al.A role for RhoA in the two-phase migratory pattern of post-otic neural crest cellsDevelopmental Biology2007ISSN 0012-1606
Bradley, William D. et al.Integrin Signaling through Arg Activates p190RhoGAP by Promoting Its Binding to p120RasGAP and Recruitment to the MembraneMolecular Biology of the Cell2006ISSN 1059-1524
AuthorTitleJournalYearArticle Link
Zhang, Jiahui et al.Phillygenin prevents osteoclast differentiation and bone loss by targeting RhoAPhytotherapy Research2024ISSN 1099--1573
Bock, Fabian et al.Rac1 promotes kidney collecting duct repair by mechanically coupling cell morphology to mitotic entryScience advances2024ISSN 2375-2548
Moztarzadeh, Sina et al.Cortactin is in a complex with VE-cadherin and is required for endothelial adherens junction stability through Rap1/Rac1 activationScientific Reports 2024 14:12024ISSN 2045--2322
González, Yasmilde Rodríguez et al.PFTK1 kinase regulates axogenesis during development via RhoA activationBMC Biology2023ISSN 1741-7007
Ye, Qian et al.Deficiency of gluconeogenic enzyme PCK1 promotes metabolic-associated fatty liver disease through PI3K/AKT/PDGF axis activation in male miceNature Communications 2023 14:12023ISSN 2041--1723
Werder, Rhiannon B. et al.The COPD GWAS gene ADGRG6 instructs function and injury response in human iPSC-derived type II alveolar epithelial cellsAmerican journal of human genetics2023ISSN 1537--6605
Toffali, Lara et al.An isoform of the giant protein titin is a master regulator of human T lymphocyte traffickingCell reports2023ISSN 2211--1247
Bartos, Katalin et al.Renal FGF23 signaling depends on redox protein Memo1 and promotes orthovanadate-sensitive protein phosphotyrosyl phosphatase activityJournal of Cell Communication and Signaling2023ISSN 1873-961X
Escuin, Sarah et al.Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouseDMM Disease Models and Mechanisms2023ISSN 1754-8411
Dang, Iren et al.Key role for Rac in the early transcriptional response to extracellular matrix stiffness and stiffness-dependent repression of ATF3Journal of Cell Science2023ISSN 1477-9137
Martínez-Rendón, Jacqueline et al.Ouabain Induces Transcript Changes and Activation of RhoA/ROCK Signaling in Cultured Epithelial Cells (MDCK)Current Issues in Molecular Biology2023ISSN 1467-3045
Rogg, Manuel et al.A YAP/TAZ–ARHGAP29–RhoA Signaling Axis Regulates Podocyte Protrusions and Integrin AdhesionsCells2023ISSN 2073-4409
Choi, Hyehun et al.LRRC8A anion channels modulate vascular reactivity via association with Myosin Phosphatase Rho Interacting Protein (MPRIP)FASEB journal : official publication of the Federation of American Societies for Experimental Biology2023ISSN 1530-6860
Lopes-Rodrigues, Vanessa et al.AraC interacts with p75NTR transmembrane domain to induce cell death of mature neuronsCell Death & Disease 2023 14:72023ISSN 2041--4889
Zhai, Ruoyang et al.Effects of sevoflurane on lung epithelial permeability in experimental models of acute respiratory distress syndromeJournal of Translational Medicine2023ISSN 1479-5876
Crespo, Grace Velez et al.The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancerMolecular Medicine2023ISSN 1528-3658
Morishita, Jun et al.Identification of a small RhoA GTPase inhibitor effective in fission yeast and human cellsOpen Biology2023ISSN 2046-2441
Anastasaki, Corina et al.Generation of human induced pluripotent stem cell-derived cerebral organoids for cellular and molecular characterizationSTAR Protocols2022ISSN 2666--1667
Zanin, Juan P. et al.p75NTR prevents the onset of cerebellar granule cell migration via RhoA activationeLife2022ISSN 2050-084X
Sánchez-de la Torre, Aníbal et al.Cannabinoid CB1 receptor gene inactivation in oligodendrocyte precursors disrupts oligodendrogenesis and myelination in miceCell Death & Disease 2022 13:72022ISSN 2041--4889
Weder, Bruce et al.New Therapeutic Approach for Intestinal Fibrosis Through Inhibition of pH-Sensing Receptor GPR4Inflammatory Bowel Diseases2022ISSN 1078--0998
Yadav, Vikas et al.Increased MARCKS Activity in BRAF Inhibitor-Resistant Melanoma Cells Is Essential for Their Enhanced Metastatic Behavior Independent of Elevated WNT5A and IL-6 SignalingCancers2022ISSN 2072-6694
Kumar, Akhilesh et al.Essential role of Rnd1 in innate immunity during viral and bacterial infectionsCell Death & Disease 2022 13:62022ISSN 2041--4889
Wang, Kankai et al.PTBP1 knockdown promotes neural differentiation of glioblastoma cells through UNC5B receptorTheranostics2022ISSN 1838-7640
de Vallière, Cheryl et al.pH-Sensing G Protein-Coupled Receptor OGR1 (GPR68) Expression and Activation Increases in Intestinal Inflammation and FibrosisInternational Journal of Molecular Sciences2022ISSN 1422-0067
Meng, Zhipeng et al.The Hippo pathway mediates Semaphorin signalingScience Advances2022ISSN 2375-2548
Darp, Revati et al.Oncogenic BRAF induces whole-genome doubling through suppression of cytokinesisNature Communications 2022 13:12022ISSN 2041--1723
Vadakumchery, Anila et al.The Small GTPase RHOA Links SLP65 Activation to PTEN Function in Pre B Cells and Is Essential for the Generation and Survival of Normal and Malignant B CellsFrontiers in Immunology2022ISSN 1664-3224
Hauke, Michael et al.Active RhoA Exerts an Inhibitory Effect on the Homeostasis and Angiogenic Capacity of Human Endothelial CellsJournal of the American Heart Association2022ISSN 2047-9980
Xue, Tan et al.Effects of Aster B-mediated intracellular accumulation of cholesterol on inflammatory process and myocardial cells in acute myocardial infarctionHellenic Journal of Cardiology2022
Francis, Caitlin R. et al.Rab35 governs apicobasal polarity through regulation of actin dynamics during sprouting angiogenesisNature Communications 2022 13:12022ISSN 2041--1723
Kumar, Akhilesh et al.Essential role of Rnd1 in innate immunity during viral and bacterial infectionsCell Death & Disease2022Article Link
Ma, Yuanyuan et al.Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during tooth root developmentDevelopment (Cambridge)2021ISSN 1477-9129
Jozic, Ivan et al.Glucocorticoid-mediated induction of caveolin-1 disrupts cytoskeletal organization, inhibits cell migration and re-epithelialization of non-healing woundsCommunications Biology2021ISSN 2399-3642
Gurusamy, Malarvizhi et al.G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediatorsNature Communications2021ISSN 2041-1723
Zhou, Qun et al.Inflammatory Immune Cytokine TNF-α Modulates Ezrin Protein Activation via FAK/RhoA Signaling Pathway in PMVECs HyperpermeabilityFrontiers in Pharmacology2021ISSN 1663-9812
Porter, Lauren et al.SUN1/2 Are Essential for RhoA/ROCK-Regulated Actomyosin Activity in Isolated Vascular Smooth Muscle CellsCells2020ISSN 2073-4409
Krueger, Irena et al.Reelin amplifies glycoprotein VI activation and alphaiib beta3 integrin outside-in signaling via PLC Gamma 2 and Rho GTPasesArteriosclerosis, Thrombosis, and Vascular Biology2020ISSN 1524-4636
Hasan, Wan Nuraini Wan et al.Annatto-derived tocotrienol promotes mineralization of MC3T3-E1 cells by enhancing BMP-2 protein expression via inhibiting RhoA activation and HMG-CoA reductase gene expressionDrug Design, Development and Therapy2020ISSN 1177-8881
Rong, Zhouyi et al.Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aβ42 in triggering receptor expressed on myeloid cells 2 loss-of-function murine modelsFASEB Journal2020ISSN 1530-6860
Lachowski, Dariusz et al.G Protein-Coupled Estrogen Receptor Regulates Actin Cytoskeleton Dynamics to Impair Cell PolarizationFrontiers in Cell and Developmental Biology2020ISSN 2296-634X
Salgado-Lucio, Monica L. et al.FAK regulates actin polymerization during sperm capacitation via the ERK2/GEF-H1/RhoA signaling pathwayJournal of Cell Science2020ISSN 1477-9137
Dias Gomes, Martim et al.Polarity signaling ensures epidermal homeostasis by coupling cellular mechanics and genomic integrityNature Communications2019ISSN 2041-1723
Majolée, Jisca et al.CSN5 inhibition triggers inflammatory signaling and Rho/ROCK-dependent loss of endothelial integrityScientific Reports2019ISSN 2045-2322
Santhana Kumar, Karthiga et al.TGF-β Determines the Pro-migratory Potential of bFGF Signaling in MedulloblastomaCell Reports2018ISSN 2211-1247
Li, Xu et al.A positive feedback loop of profilin-1 and RhoA/ROCK1 promotes endothelial dysfunction and oxidative stressOxidative Medicine and Cellular Longevity2018ISSN 1942-0994
Patra, Vijay Kumar et al.The Skin Microbiome: Is It Affected by UV-induced Immune Suppression?Frontiers in Microbiology2016ISSN 1664-302X
Lu, Wen Juan et al.Senescence Mediated by p16INK4a Impedes Reprogramming of Human Corneal Endothelial Cells into Neural Crest ProgenitorsScientific Reports2016ISSN 2045-2322
Yu, Yonghao et al.Hydrogen-rich medium ameliorates lipopolysaccharide-induced barrier dysfunction via rhoa-mdia1 signaling in caco-2 cellsShock2016ISSN 1540-0514
López-Posadas, Rocío et al.Rho-A prenylation and signaling link epithelial homeostasis to intestinal inflammationJournal of Clinical Investigation2016ISSN 1558-8238
Rom, Slava et al.The dual action of poly(ADP-ribose) polymerase -1 (PARP-1) inhibition in HIV-1 infection: HIV-1 ltr inhibition and diminution in Rho GTPase activityFrontiers in Microbiology2015ISSN 1664-302X
Tang, Xiao et al.HCLOCK Causes Rho-Kinase-Mediated Endothelial Dysfunction and NF-κ B-Mediated Inflammatory ResponsesOxidative Medicine and Cellular Longevity2015ISSN 1942-0994
Manukyan, Arkadi et al.A complex of p190RhoGAP-A and anillin modulates RhoA-GTP and the cytokinetic furrow in human cellsJournal of Cell Science2015ISSN 1477-9137
Rom, Slava et al.Poly(ADP-ribose) polymerase-1 inhibition in brain endothelium protects the blood-brain barrier under physiologic and neuroinflammatory conditionsJournal of Cerebral Blood Flow and Metabolism2015ISSN 1559-7016
Herr, Michael J. et al.Tetraspanin CD9 regulates cell contraction and actin arrangement via RhoA in human vascular smooth muscle cellsPLoS ONE2014ISSN 1932-6203
Biechler V., Stefanie V. et al.The impact of flow-induced forces on the morphogenesis of the outflow tractFrontiers in Physiology2014ISSN 1664-042X
Mackay, Joanna L. et al.Simultaneous and independent tuning of RhoA and Rac1 activity with orthogonally inducible promotersIntegrative Biology (United Kingdom)2014ISSN 1757-9708
Chen, Xiaofei et al.The TMEFF2 tumor suppressor modulates integrin expression, RhoA activation and migration of prostate cancer cellsBiochimica et Biophysica Acta - Molecular Cell Research2014ISSN 1879-2596
Zhu, Ying Ting et al.Knockdown of both p120 catenin and kaiso promotes expansion of human corneal endothelial monolayers via rhoa-rock-noncanonical BMP-NFκB pathwayInvestigative Ophthalmology and Visual Science2014ISSN 1552-5783
Papke, Christina L. et al.Smooth muscle hyperplasia due to loss of smooth muscle α-actin is driven by activation of focal adhesion kinase, altered p53 localization and increased levels of platelet-derived growth factor receptor-βHuman Molecular Genetics2013ISSN 0964-6906
Tan, Hong et al.Fluid flow forces and rhoA regulate fibrous development of the atrioventricular valvesDevelopmental Biology2013ISSN 1095-564X
Kalia, Manjula et al.Japanese Encephalitis Virus Infects Neuronal Cells through a Clathrin-Independent Endocytic MechanismJournal of Virology2013ISSN 0022--538X
Kanazawa, Yasushi et al.The Rho-kinase inhibitor fasudil restores normal motor nerve conduction velocity in diabetic rats by assuring the proper localization of adhesion-related molecules in myelinating Schwann cellsExperimental neurology2013ISSN 1090--2430
DiScipio, Richard G. et al.Complement C3a signaling mediates production of angiogenic factors in mesenchymal stem cellsJournal of Biomedical Science and Engineering2013ISSN 1937--6871
Chen, Guang et al.Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells (Journal of Biological Chemistry (2012) 2Journal of Biological Chemistry2012ISSN 0021-9258
Greco, Carolina M. et al.Chemotactic effect of prorenin on human aortic smooth muscle cells: a novel function of the (pro)renin receptorCardiovascular Research2012ISSN 0008--6363
Dhaliwal, Anandika et al.Cellular Cytoskeleton Dynamics Modulates Non-Viral Gene Delivery through RhoGTPases2012PMID 22509380
Ramsay, Alan G. et al.Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenali******: Establishing a reversible immune evasion mechanism in human cancerBlood2012ISSN 1528-0020
Chen, Si Meng et al.Inhibition of tumor cell growth, proliferation and migration by X-387, a novel active-site inhibitor of mTORBiochemical Pharmacology2012ISSN 0006-2952
Howe, Grant A. et al.RhoB controls endothelial cell morphogenesis in part via negative regulation of RhoAVascular Cell2012ISSN 2045--824X
Yang, Seungwon et al.The RhoA-ROCK-PTEN pathway as a molecular switch for anchorage dependent cell behaviorBiomaterials2012ISSN 1878--5905
Garrido‐Gómez, Tamara et al.Annexin A2 is critical for embryo adhesiveness to the human endometrium by RhoA activation through F‐actin regulationThe FASEB Journal2012ISSN 0892--6638
Zhou, Zhigang et al.HSV-mediated gene transfer of C3 transferase inhibits Rho to promote axonal regenerationExperimental Neurology2012ISSN 0014--4886
McCoy, Kelly L. et al.Protease-activated receptor 1 (PAR1) coupling to G(q/11) but not to G(i/o) or G(12/13) is mediated by discrete amino acids within the receptor second intracellular loopCellular signalling2012ISSN 1873--3913
Ramseyer, Vanesa D. et al.Tumor necrosis factor α decreases nitric oxide synthase type 3 expression primarily via Rho/Rho kinase in the thick ascending limbHypertension (Dallas, Tex. : 1979)2012ISSN 1524--4563
Takefuji, Mikito et al.G13-mediated signaling pathway is required for pressure overload-induced cardiac remodeling and heart failureCirculation2012ISSN 0009-7322
Jin, Wanzhu et al.Increased SRF transcriptional activity in human and mouse skeletal muscle is a signature of insulin resistanceJournal of Clinical Investigation2011ISSN 0021-9738
Aguilar, Hector N. et al.Phos-tag-based analysis of myosin regulatory light chain phosphorylation in human uterine myocytesPLoS ONE2011ISSN 1932-6203
Ganguly, Riya et al.Adiponectin Increases LPL Activity via RhoA/ROCK-Mediated Actin Remodelling in Adult Rat CardiomyocytesEndocrinology2011ISSN 0013--7227
Musso, Alessandra et al.Relevance of the mevalonate biosynthetic pathway in the regulation of bone marrow mesenchymal stromal cell-mediated effects on T-cell proliferation and B-cell survivalHaematologica2011ISSN 1592--8721
Lichtenstein, Mathieu P. et al.Secretase-independent and RhoGTPase/PAK/ERK-dependent regulation of cytoskeleton dynamics in astrocytes by NSAIDs and derivativesJournal of Alzheimer's disease : JAD2010ISSN 1875--8908
Ridgway, Lon D. et al.Modulation of GEF-H1 Induced Signaling by Heparanase in Brain Metastatic Melanoma CellsJournal of cellular biochemistry2010ISSN 0730-2312
Rapier, Rebecca et al.The extracellular matrix microtopography drives critical changes in cellular motility and Rho A activity in colon cancer cellsCancer Cell International2010ISSN 1475-2867
Romero, Ana M. et al.Chronic ethanol exposure alters the levels, assembly, and cellular organization of the actin cytoskeleton and microtubules in hippocampal neurons in primary cultureToxicological Sciences2010ISSN 1096-6080
Nini, Lylia et al.Accurate and reproducible measurements of RhoA activation in small samples of primary cellsAnalytical biochemistry2010ISSN 1096--0309
Yang, Enyue et al.Fluoride induces vascular contraction through activation of RhoA/Rho kinase pathway in isolated rat aortasEnvironmental toxicology and pharmacology2010ISSN 1872--7077
Hammar, Eva et al.Role of the Rho-ROCK (Rho-Associated Kinase) Signaling Pathway in the Regulation of Pancreatic β-Cell FunctionEndocrinology2009ISSN 0013--7227
Chastre, Eric et al.TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasivenessThe FASEB Journal2009ISSN 1530--6860
Seifert, Jennifer L. et al.Differential activation of Rac1 and RhoA in neuroblastoma cell fractionsNeuroscience letters2009ISSN 0304--3940
Ramirez, Servio H. et al.Activation of Peroxisome Proliferator-Activated Receptor γ (PPARγ) Suppresses Rho GTPases in Human Brain Microvascular Endothelial Cells and Inhibits Adhesion and Transendothelial Migration of HIV-1 Infected MonocytesThe Journal of Immunology2008ISSN 0022--1767
Kinoshita, Nagatoki et al.Apical Accumulation of Rho in the Neural Plate Is Important for Neural Plate Cell Shape Change and Neural Tube FormationMolecular Biology of the Cell2008ISSN 1059-1524
Mercer, Jason et al.Vaccinia virus uses macropinocytosis and apoptotic mimicry to enter host cellsScience (New York, N.Y.)2008ISSN 1095--9203
Sequeira, Linda et al.Rho GTPases in PC-3 prostate cancer cell morphology, invasion and tumor cell diapedesisClinical & experimental metastasis2008ISSN 0262--0898
Moore, Simon W. et al.Rho inhibition recruits DCC to the neuronal plasma membrane and enhances axon chemoattraction to netrin 1Development2008ISSN 0950--1991
Korobova, Farida et al.Arp2/3 complex is important for filopodia formation, growth cone motility, and neuritogenesis in neuronal cellsMolecular biology of the cell2008ISSN 1939--4586
Tanaka, Shigeru et al.Neural expression of G protein-coupled receptors GPR3, GPR6, and GPR12 up-regulates cyclic AMP levels and promotes neurite outgrowthThe Journal of biological chemistry2007ISSN 0021--9258
Schreibelt, Gerty et al.Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signalingFASEB journal : official publication of the Federation of American Societies for Experimental Biology2007ISSN 1530--6860
Keely, Patricia J. et al.Investigating integrin regulation and signaling events in three-dimensional systemsMethods in enzymology2007ISSN 0076--6879
Rupp, Paul A. et al.A role for RhoA in the two-phase migratory pattern of post-otic neural crest cellsDevelopmental Biology2007ISSN 0012-1606
Bradley, William D. et al.Integrin Signaling through Arg Activates p190RhoGAP by Promoting Its Binding to p120RasGAP and Recruitment to the MembraneMolecular Biology of the Cell2006ISSN 1059-1524
AuthorTitleJournalYearArticle Link
Escuin, Sarah et al.Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouseDMM Disease Models and Mechanisms2023ISSN 1754-8411
Zhai, Ruoyang et al.Effects of sevoflurane on lung epithelial permeability in experimental models of acute respiratory distress syndromeJournal of Translational Medicine2023ISSN 1479-5876
Lee, Sang Joon et al.AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defenceNature2021ISSN 1476-4687
Porter, Lauren et al.SUN1/2 Are Essential for RhoA/ROCK-Regulated Actomyosin Activity in Isolated Vascular Smooth Muscle CellsCells2020ISSN 2073-4409
Lachowski, Dariusz et al.G Protein-Coupled Estrogen Receptor Regulates Actin Cytoskeleton Dynamics to Impair Cell PolarizationFrontiers in Cell and Developmental Biology2020ISSN 2296-634X
Chronopoulos, Antonios et al.Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathwayNature Materials2020ISSN 1476-4660
Ngai, David et al.DDR1 (Discoidin Domain Receptor-1)-RhoA (Ras Homolog Family Member A) Axis Senses Matrix Stiffness to Promote Vascular CalcificationArteriosclerosis, Thrombosis, and Vascular Biology2020ISSN 1524-4636
Haq, Naila et al.Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neuronsPLoS Biology2019ISSN 1545-7885
Dér, Bálint et al.NK2 receptor-mediated detrusor muscle contraction involves Gq/11-dependent activation of voltage-dependent Ca2+ channels and the RhoA-Rho kinase pathwayAmerican Journal of Physiology - Renal Physiology2019ISSN 1522-1466
Peng, Jing Hua et al.Geniposide and Chlorogenic Acid Combination Ameliorates Non-alcoholic Steatohepatitis Involving the Protection on the Gut Barrier Function in Mouse Induced by High-Fat DietFrontiers in Pharmacology2018ISSN 1663-9812
Giannini, Marianna et al.Nano-topography: Quicksand for cell cycle progression?Nanomedicine: Nanotechnology, Biology, and Medicine2018ISSN 1549-9642
Zhang, Xiaoqing et al.Alterations of MEK1/2-ERK1/2, IFNγ and Smad2/3 associated Signalling pathways during cryopreservation of ASCs affect their differentiation towards VSMC-like cellsStem Cell Research2018ISSN 1876-7753
Tod, Jo et al.Pro-migratory and TGF-β-activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switchJournal of Pathology2017ISSN 1096-9896
Schillaci, Odessa et al.Exosomes from metastatic cancer cells transfer amoeboid phenotype to non-metastatic cells and increase endothelial permeability: Their emerging role in tumor heterogeneityScientific Reports2017ISSN 2045-2322
Kempf, Anissa et al.Control of Cell Shape, Neurite Outgrowth, and Migration by a Nogo-A/HSPG InteractionDevelopmental Cell2017ISSN 1878-1551
Dyberg, Cecilia et al.Rho-associated kinase is a therapeutic target in neuroblastomaProceedings of the National Academy of Sciences of the United States of America2017ISSN 1091-6490
Yuan, Xue et al.Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiationNature Communications2016ISSN 2041-1723
Jiang, Lisheng et al.Selective activation of CB2 receptor improves efferocytosis in cultured macrophagesLife Sciences2016ISSN 1879-0631
Al-Shboul, OthmanThe role of the RhoA/ROCK pathway in gender-dependent differences in gastric smooth muscle contractionJournal of Physiological Sciences2016ISSN 1880-6546
Park, Yong Hwan et al.Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDSNature Immunology2016ISSN 1529-2916
Skrbic, Biljana et al.Lack of collagen VIII reduces fibrosis and promotes early mortality and cardiac dilatation in pressure overload in miceCardiovascular Research2015ISSN 1755-3245
Escuin, Sarah et al.Rho-kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closureJournal of Cell Science2015ISSN 1477-9137
Herr, Michael J. et al.Tetraspanin CD9 regulates cell contraction and actin arrangement via RhoA in human vascular smooth muscle cellsPLoS ONE2014ISSN 1932-6203
Biechler V., Stefanie V. et al.The impact of flow-induced forces on the morphogenesis of the outflow tractFrontiers in Physiology2014ISSN 1664-042X
Suen, J. Y. et al.Pathway-selective antagonism of proteinase activated receptor 2British Journal of Pharmacology2014ISSN 1476-5381
Tan, Hong et al.Fluid flow forces and rhoA regulate fibrous development of the atrioventricular valvesDevelopmental Biology2013ISSN 1095-564X
Valtcheva, Nadejda et al.The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42Journal of Biological Chemistry2013ISSN 0021-9258
AuthorTitleJournalYearArticle Link
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Activation of RhoA in Alcohol-Induced Intestinal Barrier Dysfunction | Request PDFArticle Link
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