Spirochrome: Flipper-TR Membrane Tension Probes

Flipper-TR® (by Spirchrome) is a live cell fluorescent membrane tension probe that simplifies the methodology for investigating changes in membrane tension when used in combination with standard fluorescence lifetime measurements (see Flipper-TR FAQ for practical details). 

Qualities of the probe:

    • Bright and fluorogenic
    • Lipophilic plasma membrane probes
    • Measure live cell tension in real-time
    • Measure endoplasmic reticulum, mitochondria, and lysosome tension

Click Here to learn more about Flipper-TR® fluorescent cell membrane tension probes

Click Here to learn more about Organelle Specific Flipper-TR® membrane tension probes

Cytoskeleton, Inc. is the exclusive provider of Spirochrome, Ltd. products in North America.

LT-organelle-flipper-v4.0

Legend:Changes in plasma membrane tension alter the planarizable Flipper-TR probe. Altering the position of the fluorescent groups produces different fluorescent lifetimes, which are quantified with FLIM microscopy.

  1. Flipper-TR Kit for fluorescence cell membrane microscopy CY-SC020
    Flipper-TR Kit, a probe for measuring plasma-membrane tension.
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  2. Mito Flipper-TR Kit for fluorescence cell membrane microscopy CY-SC023

    Mito Flipper-TR Kit, a probe for measuring plasma-membrane tension.

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  3. Lyso Flipper-TR Kit for fluorescence cell membrane microscopy CY-SC022

    Lyso Flipper-TR Kit, a probe for measuring plasma-membrane tension.

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  4. ER Flipper-TR Kit for fluorescence cell membrane microscopy CY-SC021

    ER Flipper-TR Kit, a probe for measuring plasma-membrane tension.

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