Spirochrome: SPY™ Probes

In 2015, Cytoskeleton introduced multiple live cell imaging probes from Spirochrome Ltd. These revolutionary probes simplified and streamlined live cell imaging. Cytoskeleton is excited to introduce the next generation of Spirochrome’s live cell imaging probes - the SPY™ probes. SPY™ probes improve upon the SiR and SiR700 live cell imaging probes in the far-red channels while also expanding the fluorophore labeling options for the study of F-actin, microtubules, and DNA in living cells.

Spirochrome’s SPY™ probes Advantages:
• Increased cell membrane permeability
• Verapamil no longer needed for consistent staining
• Improved compatibility across more cell lines
• Less cytotoxic than SiR probes
• Increased spectra range: FITC, TRITC, and Texas Red

Click Here to see a recent newsletter highlighting our iive cell probes

Cytoskeleton, Inc. is the exclusive provider of Spirochrome, Ltd. products in North America.

Click Here to see a spotlight of these SPY™ tools

  1. Actin Test Kit Spirochrome Bioprobe CY-SC500

    Fluorescent actin probes kit for F-actin live cell imaging. 

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  2. CPY-CA CY-SC306

    Carbopyronine-chloroalkane ligand for Halotag™ labeling

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  3. Halo-Flipper CY-SC026

    Localizable Flipper-TR® membrane tension

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  4. SiR-CA CY-SC506

    SiR-chloroalkane ligand for Halotag™ labeling 

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  5. SPY505-CA CY-SC106

    SPY505-ChloroAlkane ligand for Halotag™ labeling

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  6. SPY555-CA CY-SC206

    SPY555-ChloroAlkane ligand for Halotag™ labeling 

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  7. SPY700-CA CY-SC606

    SPY700-ChloroAlkane ligand for Halotag™ labeling

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  8. SPY650-FastAct_X CY-SC502

    Live Cell Fluorogenic F-actin Labelling Probe

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