• Sign In
  • Create an Account
  • Contact Us
  • Quick Order
  • Compare ()
Toggle Nav
Cart 0
Menu
Account

Cytoskeleton Inc Tubulin Validation Data and Citations

Tubulin Product Citations

Antibodies

ATN02: Anti-alpha/beta Tubulin - Sheep Polycloncal

AuthorTitleJournalYearArticle Link
Guo, Yujin et al.Design, synthesis and biological evaluation of novel podophyllotoxin derivatives as tubulin-targeting anticancer agentsPharmaceutical Biology2024
Subbiah, Abirami et al.CP110 and CEP135 Localize Near the Proximal Centriolar Remnants of Mice SpermatozoamicroPublication Biology2024
Gao, Da Peng et al.Chronic Alcohol Exposure Alters the Levels and Assembly of the Actin Cytoskeleton and Microtubules in the Adult Mouse HippocampusJournal of Integrative Neuroscience2024
Brand, Nathan R et al.Novel dual action PARP and microtubule polymerization inhibitor AMXI-5001 powerfully inhibits growth of esophageal carcinoma both alone and in combination with radiotherapyAmerican Journal of Cancer Research2024
DeTemple, Viola K. et al.Anti-tumor effects of tirbanibulin in squamous cell carcinoma cells are mediated via disruption of tubulin-polymerizationArchives of Dermatological Research2024
Stonyte, Vilte et al. The GCN2 / eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity EMBO reports2023
Cree, Tabitha et al.FKBP25 regulates myoblast viability and migration and is differentially expressed in in vivo models of muscle adaptationThe FEBS Journal2023
Pust, Sascha et al.Vesicle-mediated transport of ALIX and ESCRT-III to the intercellular bridge during cytokinesisCellular and Molecular Life Sciences 2023 80:82023
Turner, Katerina A. et al.CP110 and CEP135 localize near the proximal and distal centrioles of cattle and human spermatozoamicroPublication Biology2023
Turner, Katerina A. et al.Tubulin posttranslational modifications modify the atypical spermatozoon centriolemicroPublication Biology2022
Alata, Milvia et al.H-ABC tubulinopathy revealed by label-free second harmonic generation microscopyScientific Reports 2022 12:12022
Guerra San Juan, Irune et al.Loss of mouse Stmn2 function causes motor neuropathyNeuron2022
Kriek, Neline et al.Cucurbitacins elicit anti-platelet activity via perturbation of the actin cytoskeleton and integrin function.Thrombosis and Haemostasis2022
Ibarrola-Vannucci, Ana K. et al.Characterization and functional analysis of the proteins Prohibitin 1 and 2 in Trypanosoma cruziPLOS Neglected Tropical Diseases2021
Dixon, Charles R. et al.STING nuclear partners contribute to innate immune signaling responsesiScience2021
Creighton, Blake A. et al.Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3AeLife2021
Xie, Xuan et al.α-TubK40me3 is required for neuronal polarization and migration by promoting microtubule formationNature Communications2021
Kumar Gaire, Sunil et al.Accelerating multicolor spectroscopic single-molecule localization microscopy using deep learningBiomedical Optics Express2020
Batlle, Cristina et al.hnRNPDL Phase Separation Is Regulated by Alternative Splicing and Disease-Causing Mutations Accelerate Its AggregationCell Reports2020
Samson, Andre L. et al.MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosisNature Communications2020
Song, Ki Hee et al.Symmetrically dispersed spectroscopic single-molecule localization microscopyLight: Science and Applications2020
Lemjabbar-Alaoui, Hassan et al.AMXI-5001, a novel dual parp1/2 and microtubule polymerization inhibitor for the treatment of human cancers.American journal of cancer research2020
Yang, Yu et al.Identification of the repressive domain of the negative circadian clock component CHRONOInternational Journal of Molecular Sciences2020
Hirst, William G. et al.Differences in Intrinsic Tubulin Dynamic Properties Contribute to Spindle Length Control in Xenopus SpeciesCurrent Biology2020
Roldán, Adrian Saul Jimenez et al.3,3′-Thiodipropanol As a Versatile Refractive Index-Matching Mounting Medium for Fluorescence MicroscopyBiomedical Optics Express2019
Fu, Meng meng et al.The Golgi Outpost Protein TPPP Nucleates Microtubules and Is Critical for MyelinationCell2019
Sasaki, Takema et al.A Novel Katanin-Tethering Machinery Accelerates CytokinesisCurrent Biology2019
Song, Ki-Hee et al.Three-dimensional biplane spectroscopic single-molecule localization microscopy: erratumOptica2019
Even, Aviel et al.ATAT1-enriched vesicles promote microtubule acetylation via axonal transportScience Advances2019
Lie-Jensen, Anette et al.Centralspindlin Recruits ALIX to the Midbody during Cytokinetic Abscission in Drosophila via a Mechanism Analogous to Virus BuddingCurrent Biology2019
Schopfer, Lawrence M. et al.Chlorpyrifos oxon promotes tubulin aggregation via isopeptide cross-linking between diethoxyphospho-Lys and Glu or ASP: Implications for neurotoxicityJournal of Biological Chemistry2018
Morelli, Giovanni et al.p27Kip1 Modulates Axonal Transport by Regulating α-Tubulin Acetyltransferase 1 StabilityCell Reports2018
Xu, Xiaoxue et al.Probenecid disrupts a novel pannexin 1-collapsin response mediator protein 2 interaction and increases microtubule stabilityFrontiers in Cellular Neuroscience2018
Stojkov, Darko et al.ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formationJournal of Cell Biology2017
Winfree, Lilly M. et al.Protein phosphatase 4 coordinates glial membrane recruitment and phagocytic clearance of degenerating axons in DrosophilaCell Death and Disease2017
Lee, Yuh Ru Julie et al.The Mitotic Function of Augmin Is Dependent on Its Microtubule-Associated Protein Subunit EDE1 in Arabidopsis thalianaCurrent Biology2017
Horita, Henrick et al.Identifying Regulatory Posttranslational Modifications of PD-L1: A Focus on MonoubiquitinatonNeoplasia (United States)2017
Zhang, Yu Shrike et al.Hybrid Microscopy: Enabling Inexpensive High-Performance Imaging through Combined Physical and Optical MagnificationsScientific Reports2016
Westmoreland, D. et al.Super-resolution microscopy as a potential approach to diagnosis of platelet granule disordersJournal of Thrombosis and Haemostasis2016
Zimmermann, Maike et al.Cyclin G2 promotes cell cycle arrest in breast cancer cells responding to fulvestrant and metformin and correlates with patient survivalCell Cycle2016
Bouge, Anne Laure et al.Tau excess impairs mitosis and kinesin-5 function, leading to aneuploidy and cell deathDMM Disease Models and Mechanisms2016
Ferraro, Francesco et al.Weibel-Palade body size modulates the adhesive activity of its von Willebrand Factor cargo in cultured endothelial cellsScientific Reports2016
Tillberg, Paul W. et al.Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodiesNature Biotechnology2016
Berruti, Giovanna et al.USP8/UBPy-regulated sorting and the development of sperm acrosome: The recruitment of METReproduction2015
Petrini, Stefania et al.Intracellular distribution of glutathionylated proteins in cultured dermal fibroblasts by immunofluorescenceMethods in Molecular Biology2015
Valenzuela-Iglesias, A. et al.Profilin1 regulates invadopodium maturation in human breast cancer cellsEuropean Journal of Cell Biology2015
McLane, Joshua S. et al.Palladin Mediates Stiffness-Induced Fibroblast Activation in the Tumor MicroenvironmentBiophysical Journal2015
Piroli, Gerardo G. et al.Identification of protein succination as a novel modification of tubulinBiochemical Journal2014
Lepicard, Simon et al.A presynaptic role of microtubule-associated protein 1/Futsch in Drosophila: Regulation of active zone number and neurotransmitter releaseJournal of Neuroscience2014
Zimmermann, Maike et al.Elevated cyclin G2 expression intersects with DNA damage checkpoint signaling and is required for a potent G2/M checkpoint arrest response to doxorubicinJournal of Biological Chemistry2012
Racedo, S. E. et al.Dynamic changes of the Golgi apparatus during bovine in vitro oocyte maturationReproduction2012
Ho, Chin Min Kimmy et al.Augmin plays a critical role in organizing the spindle and phragmoplast microtubule arrays in ArabidopsisThe Plant cell2011
Davis, Ashley et al.A tubulin polymerization microassay used to compare ligand efficacyMethods in Cell Biology2010
Parrotta, Luigi et al.Changes in the accumulation of α- and β-tubulin during bud development in Vitis vinifera L.Planta2010
Del Duca, Stefano et al.Effects of post-translational modifications catalysed by pollen transglutaminase on the functional properties of microtubulesand actin filamentsBiochemical Journal2009
Jin, Li Qing et al.Axon regeneration in the absence of growth cones: Acceleration by cyclic AMPJournal of Comparative Neurology2009
Fujikake, Nobuhiro et al.Heat shock transcription factor 1-activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperonesThe Journal of biological chemistry2008
Hanson, Susan M. et al.Arrestin Mobilizes Signaling Proteins to the Cytoskeleton and Redirects their ActivityJournal of Molecular Biology2007
Semenova, Irina et al.Fluorescence microscopy of microtubules in cultured cells.Methods in molecular medicine2007
Van De Wetering, C. I. et al.Erratum: Chromosomal instability and supernumerary centrosomes represent precursor defects in a mouse model of T-cell lymphoma (Cancer Research (2007) 67, (8081-8088))Cancer Research2007
Ganot, Philippe et al.Comparative organization of follicle, accessory cells and spawning anlagen in dynamic semelparous clutch manipulators, the urochordate OikopleuridaeBiology of the Cell2006
Morito, Yuki et al.Dynamics of microtubules and positioning of female pronucleus during bovine parthenogenesisBiology of Reproduction2005
Sanbe, Atsushi et al.Desmin-related cardiomyopathy in transgenic mice: A cardiac amyloidosisProceedings of the National Academy of Sciences of the United States of America2004
Payne, Christopher et al.Preferentially localized dynein and perinuclear dynactin associate with nuclear pore complex proteins to mediate genomic union during mammalian fertilizationJournal of Cell Science2003

AAC03: Acetyl-lysine Antibody Mouse Monoclonal (19C4B2.1)

AuthorTitleJournalYearArticle Link
Ahmed, Farjana et al.Human N-Alpha-Acetyltransferase 60 Promotes Influenza A Virus Infection by Dampening the Interferon Alpha SignalingFrontiers in Immunology2022
Ahmed, Farjana et al.Human N-Alpha-Acetyltransferase 60 Promotes Influenza A Virus Infection by Dampening the Interferon Alpha SignalingFrontiers in Immunology2022
Vega, Maria E. et al.Stimulation of Fibronectin Matrix Assembly by Lysine AcetylationCells2020
Aon, Miguel A. et al.Untangling Determinants of Enhanced Health and Lifespan through a Multi-omics Approach in MiceCell Metabolism2020
Elhassan, Yasir S. et al.Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory SignaturesCell Reports2019
Horita, Henrick et al.Utilizing optimized tools to investigate PTM crosstalk: Identifying potential PTM crosstalk of acetylated mitochondrial proteinsProteomes2018

Drugs and Buffers

TXD01: Paclitaxel (Taxol)

AuthorTitleJournalYearArticle Link
Robinson, Benjamin P. et al.Septin-coated microtubules promote maturation of multivesicular bodies by inhibiting their motilityJournal of Cell Biology2024
Babcock, N. S. et al.Ultraviolet Superradiance from Mega-Networks of Tryptophan in Biological ArchitecturesJournal of Physical Chemistry B2024
Ceglowski, Julia et al.TTLL12 is required for primary ciliary axoneme formation in polarized epithelial cellsEMBO Reports2024
Fan, Yuanwei et al.A divergent tumor overexpressed gene domain and oligomerization contribute to SPIRAL2 function in stabilizing microtubule minus endsThe Plant Cell2024
Narwanti, Iin et al.6-Regioisomeric 5,8-quinolinediones as potent CDC25 inhibitors against colorectal cancersEuropean Journal of Medicinal Chemistry2023
Pyrpassopoulos, Serapion et al.KIF1A is kinetically tuned to be a superengaging motor under hindering loadsProceedings of the National Academy of Sciences2023
Bleiler, Marina et al.Incorporation of 53BP1 into phase-separated bodies in cancer cells during aberrant mitosisJournal of Cell Science2023
Ortmann, Simon et al.A conserved microtubule-binding region in Xanthomonas XopL is indispensable for induced plant cell death reactionsPLOS Pathogens2023
Hsieh, Yao Yu et al.Repositioning VU-0365114 as a novel microtubule-destabilizing agent for treating cancer and overcoming drug resistanceMolecular Oncology2023
Hoshino, Asumi et al.The microtubule-severing protein UNC-45A preferentially binds to curved microtubules and counteracts the microtubule-straightening effects of TaxolJournal of Biological Chemistry2023
Hoti, Qendresa et al.Avermectin B1a Shows Potential Anti-Proliferative and Anticancer Effects in HCT-116 Cells via Enhancing the Stability of MicrotubulesCurrent Issues in Molecular Biology 2023
Guerra San Juan, Irune et al.Loss of mouse Stmn2 function causes motor neuropathyNeuron2022
Feizabadi, Mitra Shojania et al.The Effect of Tau and Taxol on Polymerization of MCF7 Microtubules In VitroInternational Journal of Molecular Sciences2022
Gibson, James M et al.Coil-to-α-helix transition at the Nup358-BicD2 interface activates BicD2 for dynein recruitmenteLife2022
Pizzi, Rita et al.Evidences of new biophysical properties of microtubulesFocus on Artificial Neural Networks2021
Sinclair, Amy N. et al.The Trypanosoma brucei subpellicular microtubule array is organized into functionally discrete subdomains defined by microtubule associated proteinsPLOS Pathogens2021
Chang, Ting Yu et al.A novel histone deacetylase inhibitor MPT0L184 dysregulates cell-cycle checkpoints and initiates unscheduled mitotic signalingBiomedicine and Pharmacotherapy2021
Habicht, Juri et al.UNC-45A breaks the microtubule lattice independently of its effects on non-muscle myosin IIJournal of Cell Science2021
Qiu, Rongde et al.Dynein activation in vivo is regulated by the nucleotide states of its AAA3 domainCurrent Biology2021
Kaur, Simranpreet et al.Expansion of the phenotypic spectrum of de novo missense variants in kinesin family member 1A (KIF1A)Human Mutation2020
Li, Faxiang et al.Cryo-em structure of vash1-svbp bound to microtubuleseLife2020
Hao, Huiwen et al.Golgi‐associated microtubules are fast cargo tracks and required for persistent cell migrationEMBO reports2020
Ait-Bouziad, Nadine et al.Phosphorylation of the overlooked tyrosine 310 regulates the structure, aggregation, and microtubule- And lipid-binding properties of TauJournal of Biological Chemistry2020
Kalra, Aarat P. et al.Investigation of the electrical properties of microtubule ensembles under cell-like conditionsNanomaterials2020
Chiolerio, Alessandro et al.On resistance switching and oscillations in tubulin microtubule dropletsJournal of Colloid and Interface Science2020
Zhou, Chen et al.Structural basis of tubulin detyrosination by VASH2/SVBP heterodimerNature Communications2019
Schimert, Kristin I. et al.Intracellular cargo transport by single-headed kinesin motorsProceedings of the National Academy of Sciences of the United States of America2019
Huang, Chao et al.FoxM1 Induced Pac******* Resistance via Activation of the FoxM1/PHB1/RAF-MEK-ERK Pathway and Enhancement of the ABCA2 TransporterMolecular Therapy - Oncolytics2019
Guedes-Dias, Pedro et al.Kinesin-3 Responds to Local Microtubule Dynamics to Target Synaptic Cargo Delivery to the PresynapseCurrent Biology2019
Li, Feiran et al.Local direction change of surface gliding microtubulesBiotechnology and Bioengineering2019
Tjioe, Marco et al.Multiple kinesins induce tension for smooth cargo transporteLife2019
Budaitis, Breane G. et al.Neck linker docking is critical for kinesin-1 force generation in cells but at a cost to motor speed and processivityeLife2019
Cloer, E. W. et al.p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2Molecular and Cellular Biology2018
Qiang, Liang et al.Tau Does Not Stabilize Axonal Microtubules but Rather Enables Them to Have Long Labile DomainsCurrent Biology2018
Ganguly, Anindya et al.Importin-β Directly Regulates the Motor Activity and Turnover of a Kinesin-4Developmental Cell2018
Sladewski, Thomas E. et al.Recruitment of two dyneins to an mRNA-dependent bicaudal D transport complexeLife2018
McIntosh, Betsy B. et al.Opposing Kinesin and Myosin-I Motors Drive Membrane Deformation and Tubulation along Engineered Cytoskeletal NetworksCurrent Biology2018
Reinemann, Dana N. et al.Processive Kinesin-14 HSET Exhibits Directional Flexibility Depending on Motor TrafficCurrent Biology2018
Melo, Esther et al.HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease ModelEBioMedicine2018
Chen, Yang et al.Visualizing Autophagic Lysosome Reformation in Cells Using In Vitro Reconstitution SystemsCurrent Protocols in Cell Biology2018
Bajaj, Rakhi et al.KNL1 Binding to PP1 and Microtubules Is Mutually ExclusiveStructure2018
Zhu, Yili et al.An in vitro Microscopy-based Assay for Microtubule-binding and Microtubule-crosslinking by Budding Yeast Microtubule-associated ProteinBio-Protocol2018
Su, Qian Peter et al.Corrigendum: Vesicle Size Regulates Nanotube Formation in the CellScientific reports2017
Kandel, Mikhail E. et al.Label-Free Imaging of Single Microtubule Dynamics Using Spatial Light Interference MicroscopyACS Nano2017
Howes, Stuart C. et al.Structural differences between yeast and mammalian microtubules revealed by cryo-EMJournal of Cell Biology2017
Reinemann, Dana N. et al.Collective Force Regulation in Anti-parallel Microtubule Gliding by Dimeric Kif15 Kinesin MotorsCurrent Biology2017
Zollo, Massimo et al.PRUNE is crucial for normal brain development and mutated in microcephaly with neurodevelopmental impairmentBrain2017
Kellogg, Elizabeth H. et al.Near-atomic cryo-EM structure of PRC1 bound to the microtubuleProceedings of the National Academy of Sciences of the United States of America2016
Du, Wanqing et al.Kinesin 1 Drives Autolysosome TubulationDevelopmental Cell2016
Matsuyama, Tomonori et al.Midaz(olam) inhibits the hypoxia-induced up-regulation of erythropoietin in the central nervous systemEuropean Journal of Pharmacology2015
Wang, Chong et al.Dynamic tubulation of mitochondria drives mitochondrial network formationCell Research2015
Batalla Mayoral, J. et al.Potencial zeta en la determinación de carga superficial de liposomas.Latin-American Journal of Physics Education2014
Howes, Stuart C. et al.Effects of tubulin acetylation and tubulin acetyltransferase binding on microtubule structureMolecular Biology of the Cell2014
Szyk, Agnieszka et al.Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferaseCell2014
Makrantoni, Vasso et al.Phosphorylation of Sli15 by Ipl1 is important for proper CPC localization and chromosome stability in Saccharomyces cerevisiaePLoS ONE2014
Kadakkuzha, Beena M. et al.High-throughput screening for small molecule modulators of motor protein kinesinAssay and Drug Development Technologies2014
Lee, Dongmin et al.Enhanced expression and purification of inositol 1,4,5-trisphosphate 3-kinase A through use of the pCold1-GST vector and a C-terminal hexahistidine tag in Escherichia coliProtein Expression and Purification2014
Hernández Candia, Carmen Noemí et al.A Minimal Optical Trapping and Imaging Microscopy SystemPLoS ONE2013
Lee, D et al.Inositol 1, 4, 5-Trisphosphate 3-Kinase A Is a Novel Microtubule-associated ProteinJournal of Biological …2012
Dempsey, Graham T. et al.Evaluation of fluorophores for optimal performance in localization-based super-resolution imagingNature Methods2011
Gutiérrez-Medina, Braulio et al.Visualizing individual microtubules by bright field microscopyAmerican Journal of Physics2010
Teckchandani, Anjali M. et al.The multidomain protooncogenic protein c-Cbl binds to tubulin and stabilizes microtubulesExperimental cell research2005
Kosturko, Linda D. et al.The Microtubule-associated Protein Tumor Overexpressed Gene Binds to the RNA Trafficking Protein Heterogeneous Nuclear Ribonucleoprotein A2Molecular Biology of the Cell2005
Nair, K. Saidas et al.Direct Binding of Visual Arrestin to Microtubules Determines the Differential Subcellular Localization of Its Splice Variants in Rod Photoreceptors *Journal of Biological Chemistry2004
Ligon, Lee A. et al.The Microtubule Plus-End Proteins EB1 and Dynactin Have Differential Effects on Microtubule PolymerizationMolecular Biology of the Cell2003
Benink, H. A. et al.Analysis of Cortical Flow Models In VivoMolecular Biology of the Cell2000
Korinek, William S. et al.Molecular linkage underlying microtubule orientation toward cortical sites in yeastScience (New York, N.Y.)2000

BST01: General Tubulin Buffer

AuthorTitleJournalYearArticle Link
Lucas, Lathan et al.Alternatively Spliced MAP4 Isoforms Have Key Roles in Maintaining Microtubule Organization and Skeletal Muscle FunctioniScience2024
Singh, Sudhir K. et al.Noncanonical interaction with microtubules via the N-terminal nonmotor domain is critical for the functions of a bidirectional kinesinScience Advances2024
Hammarin, Greger et al.No observable non-thermal effect of microwave radiation on the growth of microtubulesScientific Reports2024
Singh, Rajendra K. et al.Coordinated Biophysical Stimulation of MSCs via Electromagnetized Au-Nanofiber Matrix Regulates Cytoskeletal-to-Nuclear Mechanoresponses and Lineage SpecificationAdvanced Functional Materials2023
Feizabadi, Mitra Shojania et al.The Effect of Tau and Taxol on Polymerization of MCF7 Microtubules In VitroInternational Journal of Molecular Sciences2022
Wu, R. et al.Thermal hysteresis in microtubule assembly/disassembly dynamics: The aging-induced degradation of tubulin dimersBiochemistry and Biophysics Reports2022
Pizzi, Rita et al.Evidences of new biophysical properties of microtubulesFocus on Artificial Neural Networks2021
Hough, Cameron M. et al.Disassembly of microtubules by intense terahertz pulsesBiomedical Optics Express2021
Li, Yaxin et al.Small-Molecule HSP27 Inhibitor Abolishes Androgen Receptors in GlioblastomaJournal of Medicinal Chemistry2021
Lin, Jong Wei et al.Dexamethasone accelerates muscle regeneration by modulating kinesin-1-mediated focal adhesion signalsCell Death Discovery2021
McElmurry, Kristi et al.Dynein-mediated microtubule translocation powering neurite outgrowth in chick and Aplysia neurons requires microtubule assemblyJournal of Cell Science2020
Tuszynski, Jack A. et al.Microtubules as Sub-Cellular MemristorsScientific Reports2020
Kalra, Aarat P. et al.Behavior of α, β tubulin in DMSO-containing electrolytesNanoscale Advances2019
Melo, Esther et al.HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease ModelEBioMedicine2018
Chen, Yang et al.Visualizing Autophagic Lysosome Reformation in Cells Using In Vitro Reconstitution SystemsCurrent Protocols in Cell Biology2018
Lukinavičius, Gražvydas et al.Fluorescent dyes and probes for super-resolution microscopy of microtubules and tracheoles in living cells and tissuesChemical Science2018
Mangiatordi, Giuseppe Felice et al.Automated identification of structurally heterogeneous and patentable antiproliferative hits as potential tubulin inhibitorsChemical Biology and Drug Design2018
Santelices, Iara B. et al.Response to Alternating Electric Fields of Tubulin Dimers and Microtubule Ensembles in Electrolytic SolutionsScientific Reports2017
Tantak, Mukund P. et al.Design and synthesis of bis(indolyl)ketohydrazide-hydrazones: Identification of potent and selective novel tubulin inhibitorsEuropean Journal of Medicinal Chemistry2017
Mangiatordi, Giuseppe Felice et al.Novel chemotypes targeting tubulin at the colch***** binding site and unbiasing P-glycoproteinEuropean Journal of Medicinal Chemistry2017
DeBruhl, Heather et al.Rop, the Sec1/Munc18 homolog in Drosophila, is required for furrow ingression and stable cell shape during cytokinesisJournal of Cell Science2016
Lee, Dongmin et al.Enhanced expression and purification of inositol 1,4,5-trisphosphate 3-kinase A through use of the pCold1-GST vector and a C-terminal hexahistidine tag in Escherichia coliProtein Expression and Purification2014
Hartley, R. M. et al.Polygamain, a New Microtubule Depolymerizing Agent That Occupies a Unique Pharmacophore in the Colch***** SiteMolecular Pharmacology2012
Chen, Chun Han et al.Protopine, a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell linesCancer Letters2012
Carletti, B. et al.Effect of protein glutathionylation on neuronal cytoskeleton: a potential link to neurodegenerationNeuroscience2011
Risinger, A. L. et al.ELR510444, a novel microtubule disruptor with multiple mechanisms of actionThe Journal of pharmacology and experimental therapeutics2011
Faridi, Uzma et al.Proteomics indicates modulation of tubulin polymerization by L-menthol inhibiting human epithelial colorectal adenocarcinoma cell proliferationProteomics2011
Chang, Chia Hao et al.Mycotoxin citrinin induced cell cycle G2/M arrest and numerical chromosomal aberration associated with disruption of microtubule formation in human cellsToxicological sciences : an official journal of the Society of Toxicology2011
Ratnikova, Tatsiana A. et al.In vitro polymerization of microtubules with a fullerene derivativeACS Nano2011
Kawaratani, Yasuyuki et al.New microtubule polymerization inhibitors comprising a nitrooxymethylphenyl groupBioorganic and Medicinal Chemistry2011
O'Boyle, Niamh M. et al.Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agentsJournal of Medicinal Chemistry2010
Gutiérrez-Medina, Braulio et al.Visualizing individual microtubules by bright field microscopyAmerican Journal of Physics2010
Davis, Ashley et al.A tubulin polymerization microassay used to compare ligand efficacyMethods in Cell Biology2010
Kushkuley, Jacob et al.Neurofilament cross-bridging competes with kinesin-dependent association of neurofilaments with microtubulesJournal of cell science2009
Prager-Khoutorsky, Masha et al.Allicin inhibits cell polarization, migration and division via its direct effect on microtubulesCell Motility and the Cytoskeleton2007
Huang, Yao Ting et al.CIL-102 interacts with microtubule polymerization and causes mitotic arrest following apoptosis in the human prostate cancer PC-3 cell lineThe Journal of biological chemistry2005
Chen, Zehan et al.A-432411, a novel indolinone compound that disrupts spindle pole formation and inhibits human cancer cell growth2005

BST05: Tubulin Glycerol Buffer - Cushion Buffer

AuthorTitleJournalYearArticle Link
Sharma, Sachin et al.Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancerJournal of Enzyme Inhibition and Medicinal Chemistry2023
Lagunas-Rangel, Francisco Alejandro et al.Interaction between environmental pollutants and cancer drug efficacy: Bisphenol A, Bisphenol A diglycidyl ether and Perfluorooctanoic acid reduce vincristine cytotoxicity in acute lymphoblastic leukemia cellsJournal of Applied Toxicology2023
Hough, Cameron M. et al.Disassembly of microtubules by intense terahertz pulsesBiomedical Optics Express2021
Li, Yaxin et al.Small-Molecule HSP27 Inhibitor Abolishes Androgen Receptors in GlioblastomaJournal of Medicinal Chemistry2021
Melo, Esther et al.HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease ModelEBioMedicine2018
Bajaj, Rakhi et al.KNL1 Binding to PP1 and Microtubules Is Mutually ExclusiveStructure2018
Hartley, R. M. et al.Polygamain, a New Microtubule Depolymerizing Agent That Occupies a Unique Pharmacophore in the Colch***** SiteMolecular Pharmacology2012
Chen, Chun Han et al.Protopine, a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell linesCancer Letters2012
Carletti, B. et al.Effect of protein glutathionylation on neuronal cytoskeleton: a potential link to neurodegenerationNeuroscience2011
Risinger, A. L. et al.ELR510444, a novel microtubule disruptor with multiple mechanisms of actionThe Journal of pharmacology and experimental therapeutics2011
Faridi, Uzma et al.Proteomics indicates modulation of tubulin polymerization by L-menthol inhibiting human epithelial colorectal adenocarcinoma cell proliferationProteomics2011
Chang, Chia Hao et al.Mycotoxin citrinin induced cell cycle G2/M arrest and numerical chromosomal aberration associated with disruption of microtubule formation in human cellsToxicological sciences : an official journal of the Society of Toxicology2011
O'Boyle, Niamh M. et al.Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agentsJournal of Medicinal Chemistry2010
Kushkuley, Jacob et al.Neurofilament cross-bridging competes with kinesin-dependent association of neurofilaments with microtubulesJournal of cell science2009
Huang, Yao Ting et al.CIL-102 interacts with microtubule polymerization and causes mitotic arrest following apoptosis in the human prostate cancer PC-3 cell lineThe Journal of biological chemistry2005
Chen, Zehan et al.A-432411, a novel indolinone compound that disrupts spindle pole formation and inhibits human cancer cell growth2005

BST06: GTP

AuthorTitleJournalYearArticle Link
Robinson, Benjamin P. et al.Septin-coated microtubules promote maturation of multivesicular bodies by inhibiting their motilityJournal of Cell Biology2024
Lucas, Lathan et al.Alternatively Spliced MAP4 Isoforms Have Key Roles in Maintaining Microtubule Organization and Skeletal Muscle FunctioniScience2024
Zhang, Guohui et al.Metabolic profiling identifies Qrich2 as a novel glutamine sensor that regulates microtubule glutamylation and mitochondrial function in mouse spermCellular and Molecular Life Sciences2024
Ballmer, Daniel et al.Dynamic localization of the chromosomal passenger complex in trypanosomes is controlled by the orphan kinesins KIN-A and KIN-BeLife2024
Seo, Dahee et al.Poxvirus A51R proteins regulate microtubule stability and antagonize a cell-intrinsic antiviral responseCell Reports2024
Pyrpassopoulos, Serapion et al.KIF1A is kinetically tuned to be a superengaging motor under hindering loadsProceedings of the National Academy of Sciences2023
Garg, Ritu et al.B-type Plexins promote the GTPase activity of Ran to affect androgen receptor nuclear translocation in prostate cancerCancer Gene Therapy2023
Piroli, Gerardo G. et al.Defective function of α-ketoglutarate dehydrogenase exacerbates mitochondrial ATP deficits during complex I deficiencyRedox Biology2023
Singh, Rajendra K. et al.Coordinated Biophysical Stimulation of MSCs via Electromagnetized Au-Nanofiber Matrix Regulates Cytoskeletal-to-Nuclear Mechanoresponses and Lineage SpecificationAdvanced Functional Materials2023
Feizabadi, Mitra Shojania et al.The Effect of Tau and Taxol on Polymerization of MCF7 Microtubules In VitroInternational Journal of Molecular Sciences2022
Wu, R. et al.Thermal hysteresis in microtubule assembly/disassembly dynamics: The aging-induced degradation of tubulin dimersBiochemistry and Biophysics Reports2022
Pizzi, Rita et al.Evidences of new biophysical properties of microtubulesFocus on Artificial Neural Networks2021
Hough, Cameron M. et al.Disassembly of microtubules by intense terahertz pulsesBiomedical Optics Express2021
Qiu, Rongde et al.Dynein activation in vivo is regulated by the nucleotide states of its AAA3 domainCurrent Biology2021
Li, Yaxin et al.Small-Molecule HSP27 Inhibitor Abolishes Androgen Receptors in GlioblastomaJournal of Medicinal Chemistry2021
Kaur, Simranpreet et al.Expansion of the phenotypic spectrum of de novo missense variants in kinesin family member 1A (KIF1A)Human Mutation2020
Baker, Stacey J. et al.A Contaminant Impurity, Not Rigosertib, Is a Tubulin Binding AgentMolecular Cell2020
Kalra, Aarat P. et al.Investigation of the electrical properties of microtubule ensembles under cell-like conditionsNanomaterials2020
Budaitis, Breane G. et al.Neck linker docking is critical for kinesin-1 force generation in cells but at a cost to motor speed and processivityeLife2019
Reinemann, Dana N. et al.Processive Kinesin-14 HSET Exhibits Directional Flexibility Depending on Motor TrafficCurrent Biology2018
Melo, Esther et al.HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease ModelEBioMedicine2018
Chen, Yang et al.Visualizing Autophagic Lysosome Reformation in Cells Using In Vitro Reconstitution SystemsCurrent Protocols in Cell Biology2018
Bajaj, Rakhi et al.KNL1 Binding to PP1 and Microtubules Is Mutually ExclusiveStructure2018
Zhu, Yili et al.An in vitro Microscopy-based Assay for Microtubule-binding and Microtubule-crosslinking by Budding Yeast Microtubule-associated ProteinBio-Protocol2018
Su, Qian Peter et al.Corrigendum: Vesicle Size Regulates Nanotube Formation in the CellScientific reports2017
Reinemann, Dana N. et al.Collective Force Regulation in Anti-parallel Microtubule Gliding by Dimeric Kif15 Kinesin MotorsCurrent Biology2017
Du, Wanqing et al.Kinesin 1 Drives Autolysosome TubulationDevelopmental Cell2016
Wang, Chong et al.Dynamic tubulation of mitochondria drives mitochondrial network formationCell Research2015
Makrantoni, Vasso et al.Phosphorylation of Sli15 by Ipl1 is important for proper CPC localization and chromosome stability in Saccharomyces cerevisiaePLoS ONE2014
Lee, Dongmin et al.Enhanced expression and purification of inositol 1,4,5-trisphosphate 3-kinase A through use of the pCold1-GST vector and a C-terminal hexahistidine tag in Escherichia coliProtein Expression and Purification2014
Xiao, Xiang et al.c-Yes regulates cell adhesion at the apical ectoplasmic specialization-blood-testis barrier axis via its effects on protein recruitment and distribution2013
Hartley, R. M. et al.Polygamain, a New Microtubule Depolymerizing Agent That Occupies a Unique Pharmacophore in the Colch***** SiteMolecular Pharmacology2012
Chen, Chun Han et al.Protopine, a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell linesCancer Letters2012
Butler, Suzanne C. et al.Inhibitory effects of pectenotoxins from marine algae on the polymerization of various actin isoformsToxicology in Vitro2012
Lee, D et al.Inositol 1, 4, 5-Trisphosphate 3-Kinase A Is a Novel Microtubule-associated ProteinJournal of Biological …2012
Carletti, B. et al.Effect of protein glutathionylation on neuronal cytoskeleton: a potential link to neurodegenerationNeuroscience2011
Risinger, A. L. et al.ELR510444, a novel microtubule disruptor with multiple mechanisms of actionThe Journal of pharmacology and experimental therapeutics2011
Faridi, Uzma et al.Proteomics indicates modulation of tubulin polymerization by L-menthol inhibiting human epithelial colorectal adenocarcinoma cell proliferationProteomics2011
Chang, Chia Hao et al.Mycotoxin citrinin induced cell cycle G2/M arrest and numerical chromosomal aberration associated with disruption of microtubule formation in human cellsToxicological sciences : an official journal of the Society of Toxicology2011
Dempsey, Graham T. et al.Evaluation of fluorophores for optimal performance in localization-based super-resolution imagingNature Methods2011
Ratnikova, Tatsiana A. et al.In vitro polymerization of microtubules with a fullerene derivativeACS Nano2011
Kawaratani, Yasuyuki et al.New microtubule polymerization inhibitors comprising a nitrooxymethylphenyl groupBioorganic and Medicinal Chemistry2011
O'Boyle, Niamh M. et al.Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agentsJournal of Medicinal Chemistry2010
Gutiérrez-Medina, Braulio et al.Visualizing individual microtubules by bright field microscopyAmerican Journal of Physics2010
Davis, Ashley et al.A tubulin polymerization microassay used to compare ligand efficacyMethods in Cell Biology2010
Kushkuley, Jacob et al.Neurofilament cross-bridging competes with kinesin-dependent association of neurofilaments with microtubulesJournal of cell science2009
Huang, Yao Ting et al.CIL-102 interacts with microtubule polymerization and causes mitotic arrest following apoptosis in the human prostate cancer PC-3 cell lineThe Journal of biological chemistry2005
Chen, Zehan et al.A-432411, a novel indolinone compound that disrupts spindle pole formation and inhibits human cancer cell growth2005

PIC02: Protease Inhibitor Cocktail

AuthorTitleJournalYearArticle Link
Gao, Da Peng et al.Chronic Alcohol Exposure Alters the Levels and Assembly of the Actin Cytoskeleton and Microtubules in the Adult Mouse HippocampusJournal of Integrative Neuroscience2024
Ha, Cuong P. et al.Humanin activates integrin αV–TGFβ axis and leads to glioblastoma progressionCell Death & Disease2024
Otani, Takahito et al.The role of adhesion molecules in osteocalcin-induced effects on glucose and lipid metabolism in adipocytesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research2024
Hotani, Takuma et al.Involvement of Protein Kinase R in Double-Stranded RNA-Induced Proteasomal Degradation of Hypoxia Inducible Factor-1αInflammation2023
Chen, Shanlin et al.Aloe-emodin targets multiple signaling pathways by blocking ubiquitin-mediated degradation of DUSP1 in nasopharyngeal carcinoma cellsPhytotherapy Research2023
Yau, Eric et al.SP-R210 isoforms of Myosin18A modulate endosomal sorting and recognition of influenza A virus infection in macrophagesMicrobes and Infection2023
Wang, Yuan et al.MTSS1 curtails lung adenocarcinoma immune evasion by promoting AIP4-mediated PD-L1 monoubiquitination and lysosomal degradationCell Discovery 2023
Saldías, María Paz et al.The Cytoplasmic Region of SARAF Reduces Triple-Negative Breast Cancer Metastasis through the Regulation of Store-Operated Calcium EntryInternational Journal of Molecular Sciences2023
Román-Fernández, Alvaro et al.Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic functionScience Advances2023
Liang, Chen et al.Carboxypeptidase E Independently Changes Microtubule Glutamylation, Dendritic Branching, and Neuronal MigrationASN Neuro2022
Zhang, Yan et al.Different changes in pre- and postsynaptic components in the hippocampal CA1 subfield after transient global cerebral ischemiaBrain Structure and Function2022
Ma, Yuanyuan et al.Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during tooth root developmentDevelopment (Cambridge)2021
Fernandez, Christian et al.TMPRSS11a is a novel age-altered, tissue specific regulator of migration and wound healingFASEB Journal2021
Berganza, Eider et al.A multiplexed phospholipid membrane platform for curvature sensitive protein screeningNanoscale2021
Gu, Chunming et al.Identification of berberine as a novel drug for the treatment of multiple myeloma via targeting UHRF1BMC Biology2020
Rivas, José et al.KCTD5, a novel TRPM4-regulatory protein required for cell migration as a new predictor for breast cancer prognosisFASEB Journal2020
Park, Jin Suk et al.Mechanical regulation of glycolysis via cytoskeleton architectureNature2020
Sodhi, Chhinder P. et al. A Dynamic Variation of Pulmonary ACE2 Is Required to Modulate Neutrophilic Inflammation in Response to Pseudomonas aeruginosa Lung Infection in Mice The Journal of Immunology2019
Blanco, Constanza et al.EB1- and EB2-dependent anterograde trafficking of TRPM4 regulates focal adhesion turnover and cell invasionFASEB Journal2019
Dér, Bálint et al.NK2 receptor-mediated detrusor muscle contraction involves Gq/11-dependent activation of voltage-dependent Ca2+ channels and the RhoA-Rho kinase pathwayAmerican Journal of Physiology - Renal Physiology2019
Martin, Jennifer A. et al.A novel role for the actin-binding protein drebrin in regulating opiate addictionNature Communications2019
Tong, Jing et al.Qiliqiangxin Rescues Mouse Cardiac Function by Regulating AGTR1/TRPV1-Mediated Autophagy in STZ-Induced Diabetes MellitusCellular Physiology and Biochemistry2018
Riquelme, Denise et al.Subcellular localization and activity of TRPM4 in medial prefrontal cortex layer 2/3Frontiers in Cellular Neuroscience2018
Weise-Cross, Laura et al.Actin polymerization contributes to enhanced pulmonary vasoconstrictor reactivity after chronic hypoxiaAmerican Journal of Physiology - Heart and Circulatory Physiology2018
Horita, Henrick et al.Utilizing a comprehensive immunoprecipitation enrichment system to identify an endogenous post-translational modification profile for target proteinsJournal of Visualized Experiments2018
Horita, Henrick et al.Utilizing optimized tools to investigate PTM crosstalk: Identifying potential PTM crosstalk of acetylated mitochondrial proteinsProteomes2018
Pérez-Núñez, Ramón et al.Overexpressed Down Syndrome Cell Adhesion Molecule (DSCAM) Deregulates P21-Activated Kinase (PAK) Activity in an In Vitro Neuronal Model of Down Syndrome: Consequences on Cell Process Formation and ExtensionNeurotoxicity Research2016
Jia, Hongpeng et al.Pulmonary Epithelial TLR4 Activation Leads to Lung Injury in Neonatal Necrotizing EnterocolitisThe Journal of Immunology2016
Wang, J. et al.Erratum: The small GTPase RhoA, but not Rac1, is essential for conditioned aversive memory formation through regulation of actin rearrangements in rat dorsal hippocampus (Acta Pharmacol Sin (2013) 34 (811-8) Doi: 10.1038/aps.2013.3 )Acta Pharmacologica Sinica2014
Munnamalai, Vidhya et al.Bidirectional interactions between NOX2-type NADPH oxidase and the F-actin cytoskeleton in neuronal growth conesJournal of neurochemistry2014
Vindin, Howard et al.Validation of an algorithm to quantify changes in actin cytoskeletal organizationJournal of biomolecular screening2014
Tan, Hong et al.Fluid flow forces and rhoA regulate fibrous development of the atrioventricular valvesDevelopmental Biology2013
Yang, Jian et al.Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced cardiac hypertrophy and fibrosis in vivoInternational Journal of Biochemistry and Cell Biology2013

FtsZ Proteins

FTZ02: FtsZ protein - S. aureus recombinant 6xHis-tagged

FTZ03: FtsZ protein - S. pneumoniae recombinant 6xHis-tagged

FTZ04: FtsZ protein - E. faecalis recombinant 6xHis-tagged

AuthorTitleJournalYearArticle Link
Lu, Xi et al. Antibacterial Activity of an FtsZ Inhibitor Celastrol and Its Synergistic Effect with Vancomycin against Enterococci In Vitro and In Vivo Microbiology Spectrum2023

FTZ02: FtsZ protein - E. coli recombinant 6xHis-tagged

Kits

BK004P: Tubulin Polymerization HTS Assay, OD Based

AuthorTitleJournalYearArticle Link
Le, Thi Hung et al.Effects of Social Defeat Stress on Microtubule Regulating Proteins and Tubulin PolymerizationClinical Psychopharmacology and Neuroscience2024
Kuo, Hsiao-Hui et al.Thiostrepton induces spindle abnormalities and enhances Taxol cytotoxicity in MDA-MB-231 cellsMolecular Biology Reports2024
Seo, Dahee et al.Poxvirus A51R proteins regulate microtubule stability and antagonize a cell-intrinsic antiviral responseCell Reports2024
Jędrzejczyk, Marta et al.Novel Combretastatin A-4 Analogs—Design, Synthesis, and Antiproliferative and Anti-Tubulin ActivityMolecules2024
Guerreiro, Íris et al.The Dietary Isothiocyanate Erucin Reduces Kidney Cell Motility by Disturbing Tubulin PolymerizationMolecular Nutrition & Food Research2023
Robles-Escajeda, Elisa et al.Discovery of Ureido-Based Apcin Analogues as Cdc20-specific Inhibitors against CancerPharmaceuticals2023
Zhong, Yiming et al.Suppression of alpha-tubulin acetylation potentiates therapeutic efficacy of Eribulin in liver cancerAmerican Journal of Cancer Research2023
Argirova, Maria et al.Modulation Effect on Tubulin Polymerization, Cytotoxicity and Antioxidant Activity of 1H-Benzimidazole-2-Yl HydrazonesMolecules2023
Hoti, Qendresa et al.Avermectin B1a Shows Potential Anti-Proliferative and Anticancer Effects in HCT-116 Cells via Enhancing the Stability of MicrotubulesCurrent Issues in Molecular Biology 2023
Imamura, Yukio et al.Quantum-dot-labeled synuclein seed assay identifies drugs modulating the experimental prion-like transmissionCommunications Biology 2022
Zhou, Xiang et al.Discovery of Simple Diacylhydrazine-Functionalized Cinnamic Acid Derivatives as Potential Microtubule StabilizersInternational Journal of Molecular Sciences2022
Fang, Chieh Ting et al.Mdivi-1 induces spindle abnormalities and augments taxol cytotoxicity in MDA-MB-231 cellsCell Death Discovery 2021
Laisne, Marie Catherine et al.Characterization of microtubule destabilizing drugs: A quantitative cell‐based assay that bridges the gap between tubulin based‐ and cytotoxicity assaysCancers2021
Santelices, Iara B. et al.Response to Alternating Electric Fields of Tubulin Dimers and Microtubule Ensembles in Electrolytic SolutionsScientific Reports2017
Yi, Jun Mei et al.Dual targeting of microtubule and topoisomerase II by α-carboline derivative YCH337 for tumor proliferation and growth inhibitionOncotarget2015
Nagarajan, Shanthi et al.Tubulin Inhibitor Identification by Bioactive Conformation Alignment Pharmacophore-Guided Virtual ScreeningChemical Biology and Drug Design2015
Fu, Ying et al.Mirror-image organometallic osmium arene iminopyridine halido complexes exhibit similar potent anticancer activityChemistry - A European Journal2013
Lamberth, Clemens et al.Synthesis and fungicidal activity of tubulin polymerisation promoters. Part 2: pyridazinesBioorganic & medicinal chemistry2012
Kamal, Ahmed et al.3-substituted 2-phenylimidazo[2,1-b]benzothiazoles: synthesis, anticancer activity, and inhibition of tubulin polymerizationChemMedChem2012
Ahn, Sunjoo et al.A novel bis-indole destabilizes microtubules and displays potent in vitro and in vivo antitumor activity in prostate cancerCancer chemotherapy and pharmacology2011
Butler, Tracy R. et al.Neurodegenerative effects of recombinant HIV-1 Tat(1-86) are associated with inhibition of microtubule formation and oxidative stress-related reductions in microtubule-associated protein-2(a,b)Neurochemical research2011
Lee, Sangku et al.Biological evaluation of KRIBB3 analogs as a microtubule polymerization inhibitorBioorganic & Medicinal Chemistry Letters2011

BK006P: Tubulin Polymerization Assay >99% Pure Tubulin, OD Based

AuthorTitleJournalYearArticle Link
Shan, Peipei et al.First total synthesis, antitumor evaluation and target identification of mornaphthoate E: A new tubulin inhibitor template acting on PI3K/Akt signaling pathwayActa Pharmaceutica Sinica B2024
Wu, Yi Wen et al.Identification of selective dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors and their effects on tau and microtubuleInternational Journal of Biological Macromolecules2024
Karwt, Rawdah et al.Anticancer Potential of Pyridoxine-Based Doxorubicin Derivatives: An In Vitro StudyLife2024
Hu, Kaishun et al.CYR61 Acts as an Intracellular Microtubule-Associated Protein and Coordinates Mitotic Progression via PLK1-FBW7 PathwayInternational Journal of Biological Sciences2024
Fan, Weijing et al.A novel conductive microtubule hydrogel for electrical stimulation of chronic wounds based on biological electrical wiresJournal of Nanobiotechnology2024
Koh, Byumseok et al.Anti-cancer effects of benzimidazole derivative BNZ-111 on paclitaxel-resistant ovarian cancerGynecologic Oncology2024
Bózsity, Noémi et al.Synthesis of Estrone Heterodimers and Evaluation of Their In Vitro Antiproliferative ActivityInternational journal of molecular sciences2024
Zoroddu, Stefano et al.Identification of 3-Aryl-1-benzotriazole-1-yl-acrylonitrile as a Microtubule-Targeting Agent (MTA) in Solid TumorsInternational Journal of Molecular Sciences2024
Park, Su Jeong et al.The microtubule cytoskeleton: A validated target for the development of 2-Aryl-1H-benzo[d]imidazole derivatives as potential anticancer agentsBiomedicine & Pharmacotherapy2024
Njangiru, Isaac Kinyua et al.A Novel 2-Methoxyestradiol Derivative: Disrupting Mitosis Inhibiting Cell Motility and Inducing Apoptosis in HeLa Cells In VitroPharmaceutics2024
Yancheva, Denitsa et al.Antiproliferative and Pro-Apoptotic Activity and Tubulin Dynamics Modulation of 1H-Benzimidazol-2-yl Hydrazones in Human Breast Cancer Cell Line MDA-MB-231Molecules2024
Park, Jaebeom et al.Synthesis and evaluation of tirbanibulin derivatives: a detailed exploration of the structure–activity relationship for anticancer activityRSC Advances2023
Nagy, Viktória et al.Investigation of Anticancer Properties of Monoterpene-Aminopyrimidine Hybrids on A2780 Ovarian Cancer CellsInternational Journal of Molecular Sciences2023
Yang, Dong Lin et al.Pyrrolyldihydropyrazino[1,2-a]indoletrione Analogue Microtubule Inhibitor Induces Cell-Cycle Arrest and Apoptosis in Colorectal Cancer CellsMolecules2023
Zoroddu, Stefano et al.RNAseq Analysis of Novel 1,3,4-Oxadiazole Chalcogen Analogues Reveals Anti-Tubulin Properties on Cancer Cell LinesInternational Journal of Molecular Sciences2023
Song, In ho et al.Not all benzimidazole derivatives are microtubule destabilizing agentsBiomedicine & Pharmacotherapy2023
Tu, Huang Ju et al.Urolithin A exhibits a neuroprotective effect against Alzheimer’s disease by inhibiting DYRK1A activityJournal of Food and Drug Analysis2023
De Abreu, Isadora Rocha et al.A molecular analysis of substituted phenylethylamines as potential microtubule targeting agents through in silico methods and in vitro microtubule-polymerization activityScientific Reports 2023
Sharma, Sachin et al.Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancerJournal of Enzyme Inhibition and Medicinal Chemistry2023
Ana, Gloria et al.Synthesis and biological evaluation of 1‐(Diarylmethyl)‐1h‐1,2,4‐triazoles and 1‐(diarylmethyl)‐1h‐imidazoles as a novel class of anti‐mitotic agent for activity in breast cancerPharmaceuticals2021
Khayyat, Ahdab N. et al.Design, synthesis, and antipoliferative activities of novel substituted imidazole-thione linked benzotriazole derivativesMolecules2021
Malebari, Azizah M. et al.Synthesis and antiproliferative evaluation of 3‐chloroazetidin‐2‐ones with antimitotic activity: Heterocyclic bridged analogues of combretastatin a‐4Pharmaceuticals2021
Ibrahim, Tarek S. et al.Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effectJournal of Enzyme Inhibition and Medicinal Chemistry2021
Malebari, Azizah M. et al.β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cellsEuropean Journal of Medicinal Chemistry2020
Ibrahim, T S et al.Potent quinoline-containing combretastatin a-4 analogues: design, synthesis, antiproliferative, and anti-tubulin activityPharmaceuticals2020
Wang, Shu et al.3-Vinylazetidin-2-Ones: Synthesis, antiproliferative and tubulin destabilizing activity in MCF-7 and MDA-MB-231 Breast Cancer CellsPharmaceuticals2019
Schneidewind, Tabea et al.The Pseudo Natural Product Myokinasib Is a Myosin Light Chain Kinase 1 Inhibitor with Unprecedented ChemotypeCell Chemical Biology2019
Malebari, Azizah M. et al.β-Lactam analogues of combretastatin A-4 prevent metabolic inactivation by glucuronidation in chemoresistant HT-29 colon cancer cellsEuropean Journal of Medicinal Chemistry2017
Majellaro, Maria et al.Investigating Structural Requirements for the Antiproliferative Activity of Biphenyl NicotinamidesChemMedChem2017
Ayoub, Ahmed Taha et al.Antitumor Activity of Lankacidin Group Antibiotics Is Due to Microtubule Stabilization via a Pac*******-like MechanismJournal of Medicinal Chemistry2016
Chan, Eddie et al.The acetylenic tricyclic bis(cyano enone), TBE-31, targets microtubule dynamics and cell polarity in migrating cellsBiochimica et Biophysica Acta - Molecular Cell Research2016
Tsai, An Chi et al.In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cellsBritish Journal of Pharmacology2014
Tsai, A. C. et al.Orally active microtubule-targeting agent, MPT0B271, for the treatment of human non-small cell lung cancer, alone and in combination with erlotinibCell Death & Disease 2014
Jackson, Steven J.T. et al.Curcumin binds tubulin, induces mitotic catastrophe, and impedes normal endothelial cell proliferationFood and Chemical Toxicology2013
Hartley, R. M. et al.Polygamain, a New Microtubule Depolymerizing Agent That Occupies a Unique Pharmacophore in the Colch***** SiteMolecular Pharmacology2012
Chen, Chun Han et al.Protopine, a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell linesCancer Letters2012
Brachmann, Saskia M. et al.Characterization of the mechanism of action of the pan class i PI3K inhibitor NVP-BKM120 across a broad range of concentrationsMolecular Cancer Therapeutics2012
Carletti, B. et al.Effect of protein glutathionylation on neuronal cytoskeleton: a potential link to neurodegenerationNeuroscience2011
Risinger, A. L. et al.ELR510444, a novel microtubule disruptor with multiple mechanisms of actionThe Journal of pharmacology and experimental therapeutics2011
Faridi, Uzma et al.Proteomics indicates modulation of tubulin polymerization by L-menthol inhibiting human epithelial colorectal adenocarcinoma cell proliferationProteomics2011
Chang, Chia Hao et al.Mycotoxin citrinin induced cell cycle G2/M arrest and numerical chromosomal aberration associated with disruption of microtubule formation in human cellsToxicological sciences : an official journal of the Society of Toxicology2011
O'Boyle, Niamh M. et al.Synthesis, evaluation and structural studies of antiproliferative tubulin-targeting azetidin-2-onesBioorganic and Medicinal Chemistry2011
Geng, Feng et al.Allyl isothiocyanate arrests cancer cells in mitosis, and mitotic arrest in turn leads to apoptosis via Bcl-2 protein phosphorylationJournal of Biological Chemistry2011
O'Boyle, Niamh M. et al.Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agentsJournal of Medicinal Chemistry2010
Yang, Jai Sing et al.MJ-29 inhibits tubulin polymerization, induces mitotic arrest, and triggers apoptosis via cyclin-dependent kinase 1-mediated Bcl-2 phosphorylation in human leukemia U937 cellsJournal of Pharmacology and Experimental Therapeutics2010
Tovar, Christian et al.Small-molecule inducer of cancer cell polyploidy promotes apoptosis or senescence: Implications for therapyCell Cycle2010
Kushkuley, Jacob et al.Neurofilament cross-bridging competes with kinesin-dependent association of neurofilaments with microtubulesJournal of cell science2009
Kien, Voon Kong et al.Osmium carbonyl clusters containing labile ligands hyperstabilize microtubulesChemical Research in Toxicology2009
Huang, Yao Ting et al.CIL-102 interacts with microtubule polymerization and causes mitotic arrest following apoptosis in the human prostate cancer PC-3 cell lineThe Journal of biological chemistry2005
Jackson, Steven J.T. et al.Sulforaphane inhibits human MCF-7 mammary cancer cell mitotic progression and tubulin polymerizationJournal of Nutrition2004
Jackson, Steven J.T. et al.Sulforaphane: A naturally occuring mammary carcinoma mitotic inhibitor, which disrupts tubulin polymerizationCarcinogenesis2004

BK011: Tubulin Polymerization Assay > 99% Pure Tubulin, Fluorescence Based

AuthorTitleJournalYearArticle Link
Aggarwal, Ranjana et al.Design, Synthesis, and In Vitro Cytotoxic Studies of Some Novel Arylidene-Hydrazinyl-Thiazoles as Anticancer and Apoptosis-Inducing AgentsACS Omega2024
Zou, Zheng et al.Pocket-based lead optimization strategy for the design and synthesis of tubulin polymerization inhibitorsResults in Chemistry2024
Pospíšilová, Jana et al.Atropisomeric 1-phenylbenzimidazoles affecting microtubule organization: influence of axial chiralityOrganic & Biomolecular Chemistry2024
Abdelmegeed, Heba et al.Exploring the antitumor potential of novel quinoline derivatives via tubulin polymerization inhibition in breast cancer; design, synthesis and molecular dockingRSC Advances2024
Řehulka, Jiří et al.Click estradiol dimers with novel aromatic bridging units: synthesis and anticancer evaluationJournal of Enzyme Inhibition and Medicinal Chemistry2024
Wang, Chao et al.Design, synthesis, and bioevaluation of 1h-pyrrolo[3,2-c]pyridine derivatives as colchicine-binding site inhibitors with potent anticancer activitiesJournal of Enzyme Inhibition and Medicinal Chemistry2024
Ezelarab, Hend A.A. et al.New antiproliferative 3-substituted oxindoles inhibiting EGFR/VEGFR-2 and tubulin polymerizationMolecular Diversity2024
El-Zoghbi, Mona S. et al.Design, Synthesis and Mechanistic Study of New Dual Targeting HDAC/Tubulin InhibitorsFuture Medicinal Chemistry2024
Shahjahan, S. et al.Oxindoline Containing Thiazolidine-4-one Tethered Triazoles Act as Antimitotic Agents by Targeting Microtubule DynamicsChemistrySelect2024
Wang, Chao et al.3-aryl-4-(3,4,5-trimethoxyphenyl)pyridines inhibit tubulin polymerisation and act as anticancer agentsJournal of Enzyme Inhibition and Medicinal Chemistry2024
Xiu, Yutao et al.Design, synthesis, and bioevaluation of diarylpyrimidine derivatives as novel microtubule destabilizersFrontiers in Chemistry2024
El-Sayed, Ashraf S.A. et al.Bioprocessing of Epothilone B from Aspergillus fumigatus under solid state fermentation: Antiproliferative activity, tubulin polymerization and cell cycle analysisBMC Microbiology2024
Sun, Ning et al.The study of hon***** as a natural product-based antimicrobial agent and its potential interaction with FtsZ proteinFrontiers in Microbiology2024
Patrón, Lilian A. et al.Novel Brain-Penetrant, Small-Molecule Tubulin Destabilizers for the Treatment of GlioblastomaBiomedicines2024
Bouzriba, Chahrazed et al.Design, synthesis and biological evaluation of new 2,6-difluorinated phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new antimicrotubule agentsBioorganic Chemistry2024
Lin, H.-Y ; et al.From Sea to Science: Coral Aquaculture for Sustainable Anticancer Drug DevelopmentMarine Drugs 2024
Patterson, Jesse C. et al.Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor SignalingCancer Research2023
Payton, Marc et al.Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancersNature Cancer2023
Grzywa, Renata et al.Isothiocyanates as Tubulin Polymerization Inhibitors—Synthesis and Structure–Activity Relationship StudiesInternational Journal of Molecular Sciences2023
Hou, Zhenyan et al.S-72, a Novel Orally Available Tubulin Inhibitor, Overcomes Pac******* Resistance via Inactivation of the STING Pathway in Breast CancerPharmaceuticals2023
Liang, Baoxia et al.Novel Indole-Containing Hybrids Derived from Millepachine: Synthesis, Biological Evaluation and Antitumor Mechanism StudyMolecules2023
Wang, Chao et al.Design, synthesis, and biological evaluation of 4-aryl-9H-carbazoles as tubulin polymerization inhibitors with potent anticancer activitiesArabian Journal of Chemistry2023
Horgan, Mark James et al.Identification of Novel β-Tubulin Inhibitors Using a Combined In Silico/In Vitro ApproachJournal of Chemical Information and Modeling2023
Li, Yuan-Yuan et al.Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) impairs Postnatal Testis Development in Mice: The Microtubule Cytoskeleton as a Sensitive TargetEnvironment & Health2023
Dong, Haiyang et al.Design, synthesis and biological evaluation of tetrahydroquinoxaline sulfonamide derivatives as colch***** binding site inhibitorsRSC Advances2023
Morishita, Jun et al.Identification of a small RhoA GTPase inhibitor effective in fission yeast and human cellsOpen Biology2023
Yao, Yongfang et al.Angiogenesis and anti-leukaemia activity of novel indole derivatives as potent colch***** binding site inhibitorsJournal of Enzyme Inhibition and Medicinal Chemistry2022
Wang, Zhan et al.Design, synthesis and biological evaluation of colch***** glycoconjugates as tubulin polymerization inhibitorsBioorganic and Medicinal Chemistry2022
Ma, Juan et al.Discovery of Novel 3,4-Dihydro-2(1H)-Quinolinone Sulfonamide Derivatives as New Tubulin Polymerization Inhibitors with Anti-Cancer ActivityMolecules2022
Liu, Chao et al.Synthesis and biological evaluation of BU-4664L derivatives as potential anticancer agentsBioorganic and Medicinal Chemistry Letters2022
Kumar N, Manoj et al.Benzothiazole-[1,2,3]triazolo[5,1-a]isoindoles: Synthesis, anticancer activity, bioavailability and in silico studies against Gama-Tubulin proteinJournal of Molecular Structure2022
Woo, Jung AA et al.β-arrestin1 promotes tauopathy by transducing GPCR signaling, disrupting microtubules and autophagyLife science alliance2021
Yang, Mei et al.C118P, a novel microtubule inhibitor with anti-angiogenic and vascular disrupting activities, exerts anti-tumor effects against hepatocellular carcinomaBiochemical Pharmacology2021
Sun, Chiao Yin et al.LMBD1 protein participates in cell mitosis by regulating microtubule assemblyBiochemical Journal2021
Liang, Dong et al.Identification of anthelmintic parbendazole as a therapeutic molecule for HNSCC through connectivity map-based drug repositioningActa Pharmaceutica Sinica B2021
Rahimzadeh Oskuei, Sara et al.Design, synthesis and biological evaluation of novel imidazole-chalcone derivatives as potential anticancer agents and tubulin polymerization inhibitorsBioorganic Chemistry2021
Wang, Chao et al.Design, synthesis and biological evaluation of 1-Aryl-5-(4-arylpiperazine-1-carbonyl)-1H-tetrazols as novel microtubule destabilizersJournal of Enzyme Inhibition and Medicinal Chemistry2021
Patel, Onisha et al.Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1Communications Biology2021
Fareed, Momen R. et al.New multi-targeted antiproliferative agents: Design and synthesis of ic261-based oxindoles as potential tubulin, ck1 and egfr inhibitorsPharmaceuticals2021
Zhernov, Ilia et al.Intrinsically Disordered Domain of Kinesin-3 Kif14 Enables Unique Functional DiversityCurrent Biology2020
Baker, Stacey J. et al.A Contaminant Impurity, Not Rigosertib, Is a Tubulin Binding AgentMolecular Cell2020
Skidmore, Lillian et al.ARX788, a site-specific anti-HER2 antibody–drug conjugate, demonstrates potent and selective activity in HER2-low and T-DM1–resistant breast and gastric cancersMolecular Cancer Therapeutics2020
Wang, Yanming et al.Antibody-drug conjugate using ionized CYS-linker-mmae as the potent payload shows optimal therapeutic safetyCancers2020
Morita, Ken et al.Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2Cell2020
Dillon, Gregory M. et al.Acute inhibition of the CNS-specific kinase TTBK1 significantly lowers tau phosphorylation at several disease relevant sitesPLoS ONE2020
Ullah, Imran et al.An Antiparasitic Compound from the Medicines for Malaria Venture Pathogen Box Promotes Leishmania Tubulin PolymerizationACS Infectious Diseases2020
Song, Ming Yu et al.Exploring diverse-ring analogues on combretastatin a4 (Ca-4) olefin as microtubule-targeting agentsInternational Journal of Molecular Sciences2020
Chen, Shih Yin et al.Exosomal 2′,3′-CNP from mesenchymal stem cells promotes hippocampus CA1 neurogenesis/neuritogenesis and contributes to rescue of cognition/learning deficiencies of damaged brainStem Cells Translational Medicine2020
Zdioruk, Mykola et al.A new inhibitor of tubulin polymerization kills multiple cancer cell types and reveals p21-mediated mechanism determining cell death after mitotic catastropheCancers2020
Mirzaei, Salimeh et al.Synthesis, structure-activity relationship and molecular docking studies of novel quinoline-chalcone hybrids as potential anticancer agents and tubulin inhibitorsJournal of Molecular Structure2020
Palumbo, Valeria et al.Drosophila Morgana is an Hsp90-interacting protein with a direct role in microtubule polymerizationJournal of Cell Science2020
Barnes, Natalie G. et al.A 2-step synthesis of Combretastatin A-4 and derivatives as potent tubulin assembly inhibitorsBioorganic and Medicinal Chemistry2020
Mao, Bai Ping et al.CaMSAP2 is a microtubule minus-end targeting protein that regulates BTB dynamics through cytoskeletal organizationEndocrinology2019
Behbahani, Fatemeh Shaebani et al.Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitorsArchiv der Pharmazie2019
Cui, Ying Jie et al.Synthesis of novel pyrazole derivatives and their tumor cell growth inhibitory activityMolecules2019
Xia, Xiaoyu et al.Leukemia Cell Cycle Chemical Profiling Identifies the G2-Phase Leukemia Specific Inhibitor Leusin-1ACS Chemical Biology2019
Wang, Yanming et al.Novel silyl ether-based acid-cleavable antibody-MMAE conjugates with appropriate stability and efficacyCancers2019
Shaik, Thoukhir B. et al.Evaluation of Anticancer and Anti-Mitotic Properties of Quinazoline and Quinazolino-Benzothiadiazine DerivativesAnti-Cancer Agents in Medicinal Chemistry2019
Nixon, Gemma L. et al.Repurposing and reformulation of the antiparasitic agent flubendazole for treatment of cryptococcal meningoencephalitis, a neglected fungal diseaseAntimicrobial Agents and Chemotherapy2018
Qi, Jianguo et al.Synthesis and biological evaluation of N-substituted 3-oxo-1,2,3,4-tetrahydro-quinoxaline-6-carboxylic acid derivatives as tubulin polymerization inhibitorsEuropean Journal of Medicinal Chemistry2018
Simpkins, Scott W. et al.Predicting bioprocess targets of chemical compounds through integration of chemical-genetic and genetic interactionsPLoS Computational Biology2018
Sato-Kaneko, Fumi et al.Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer ImmunotherapyBioMed Research International2018
Dilworth, David et al.The prolyl isomerase FKBP25 regulates microtubule polymerization impacting cell cycle progression and genomic stabilityNucleic Acids Research2018
Tian, Zhenhua et al.Biological activity and interaction mechanism of the diketopiperazine derivatives as tubulin polymerization inhibitorsRSC Advances2018
Huan, L C et al.Exploration of Some Thiazolidine-2, 4-dione and 2-Oxoindoline Derivatives Incorporating 3, 4, 5-Trimethoxybenzyl Moiety as Novel Anticancer AgentsLetters in Drug …2018
Lukinavičius, Gražvydas et al.Fluorescent dyes and probes for super-resolution microscopy of microtubules and tracheoles in living cells and tissuesChemical Science2018
Chen, Minfeng et al.Pericyte-targeting prodrug overcomes tumor resistance to vascular disrupting agentsJournal of Clinical Investigation2017
Wieczorek, Anna et al.Synthesis and evaluation of biological properties of ferrocenyl-podophyllotoxin conjugatesDalton Transactions2017
Zollo, Massimo et al.PRUNE is crucial for normal brain development and mutated in microcephaly with neurodevelopmental impairmentBrain2017
Kowalczyk, Karolina et al.Colch***** metallocenyl bioconjugates showing high antiproliferative activities against cancer cell linesDalton Transactions2017
Tantak, Mukund P. et al.Design and synthesis of bis(indolyl)ketohydrazide-hydrazones: Identification of potent and selective novel tubulin inhibitorsEuropean Journal of Medicinal Chemistry2017
Sun, Maolin et al.Synthesis and bioevaluation of N,4-diaryl-1,3-thiazole-2-amines as tubulin inhibitors with potent antiproliferative activityPLoS ONE2017
Wu, Yue et al.Design and synthesis of 5-aryl-4-(4-arylpiperazine-1-carbonyl)-2H-1,2,3-triazole derivatives as colch***** binding site inhibitorsScientific Reports2017
Pearson, Brandon L. et al.Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegenerationNature Communications2016
Fukuda, Yasunori et al.Tubulin is a molecular target of the Wnt-activating chemical probeBMC Biochemistry2016
Thapa, Pritam et al.Far-Red Light-Activatable Prodrug of Pac******* for the Combined Effects of Photodynamic Therapy and Site-Specific Pac******* ChemotherapyJournal of Medicinal Chemistry2016
Yoshitake, Jun et al.Modification of tau by 8-nitroguanosine 3′,5′-cyclic monophosphate (8-nitro-cGMP): Effects of nitric oxide-linked chemical modification on tau aggregationJournal of Biological Chemistry2016
Hasanpourghadi, Mohadeseh et al.Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cellJournal of Experimental and Clinical Cancer Research2016
Cai, De et al.YSL-12, a novel microtubule-destabilizing agent, exerts potent anti-tumor activity against colon cancer in vitro and in vivoCancer Chemotherapy and Pharmacology2016
Remers, William A. et al.Synthesis and Antitumor Activity of Heterocycles Related to CarbendazimJournal of Heterocyclic Chemistry2015
Fawzy, Iten M. et al.Newly Designed and Synthesized Curcumin Analogs with in vitro Cytotoxicity and Tubulin Polymerization ActivityChemical biology & drug design2015
Seashore-Ludlow, Brinton et al.Harnessing connectivity in a large-scale small-molecule sensitivity datasetCancer Discovery2015
Yan, Jun et al.A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cellsBiochemical Pharmacology2015
Sheldon, Jonathon E. et al.Photoswitchable anticancer activity via trans-cis isomerization of a combretastatin A-4 analogOrganic and Biomolecular Chemistry2015
Calles, Antonio et al.Tivantinib (ARQ 197) efficacy is independent of MET inhibition in non-small-cell lung cancer cell linesMolecular Oncology2015
Choi, Bo Hwa et al.Suprafenacine, an Indazole-Hydrazide Agent, Targets Cancer Cells Through Microtubule DestabilizationPLOS ONE2014
Shigehiro, Tsukasa et al.Efficient Drug Delivery of Pac******* Glycoside: A Novel Solubility Gradient Encapsulation into Liposomes Coupled with Immunoliposomes PreparationPLOS ONE2014
Senese, S. et al.Chemical dissection of the cell cycle: Probes for cell biology and anti-cancer drug developmentCell Death and Disease2014
Bio, Moses et al.Far-red light activatable, multifunctional prodrug for fluorescence optical imaging and combinational treatmentJournal of Medicinal Chemistry2014
Mäki-Jouppila, Jenni H.E. et al.Centmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular interaction field and antimitotic cellular phenotype as rigosertib, on 01910.NaMolecular Cancer Therapeutics2014
Bio, Moses et al.Site-specific and far-red-light-activatable prodrug of combretastatin A-4 using photo-unclick chemistryJournal of Medicinal Chemistry2013
Sidhaye, Venkataramana K. et al.A Novel Role for Aquaporin-5 in Enhancing Microtubule Organization and StabilityPLOS ONE2012
Zach, Frank et al.The retinitis pigmentosa 28 protein FAM161A is a novel ciliary protein involved in intermolecular protein interaction and microtubule associationHuman molecular genetics2012
Fitzgerald, Daniel P. et al.TPI-287, a new taxane family member, reduces the brain metastatic colonization of breast cancer cellsMolecular Cancer Therapeutics2012
Nguyen, Tam Luong et al.Evading Pgp activity in drug-resistant cancer cells: A structural and functional study of antitubulin furan metotica compoundsMolecular Cancer Therapeutics2012
Dyrager, Christine et al.Inhibitors and promoters of tubulin polymerization: synthesis and biological evaluation of chalcones and related dienones as potential anticancer agentsBioorganic & medicinal chemistry2011
Hwang, Ji Hwan et al.Induction of tubulin polymerization and apoptosis in malignant mesothelioma cells by a new compound JBIR-23Cancer letters2011
Kim, Insook et al.Zinc stimulates tau S214 phosphorylation by the activation of Raf/mitogen-activated protein kinase-kinase/extracellular signal-regulated kinase pathwayNeuroReport2011
Kawaratani, Yasuyuki et al.New microtubule polymerization inhibitors comprising a nitrooxymethylphenyl groupBioorganic and Medicinal Chemistry2011
Oussenko, Irina A. et al.Effect of on 01910.Na, an anticancer mitotic inhibitor, on cell-cycle progression correlates with RanGAP1 hyperphosphorylationCancer Research2011

BK038: Microtubule/Tubulin In Vivo Assay Biochem Kit

AuthorTitleJournalYearArticle Link
Gao, Da Peng et al.Chronic Alcohol Exposure Alters the Levels and Assembly of the Actin Cytoskeleton and Microtubules in the Adult Mouse HippocampusJournal of Integrative Neuroscience2024
Damuka, Naresh et al.Exploring microtubule dynamics in Alzheimer's disease: Longitudinal assessment using [11C]MPC-6827 PET imaging in rodent models of Alzheimer's-related pathologyAlzheimer's & Dementia2024
DeTemple, Viola K. et al.Anti-tumor effects of tirbanibulin in squamous cell carcinoma cells are mediated via disruption of tubulin-polymerizationArchives of Dermatological Research2024
Wang, Lingling et al.Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actinReproductive Biology and Endocrinology 2024
Hwang, Hyun Jung et al.YTHDF2 facilitates aggresome formation via UPF1 in an m6A-independent mannerNature Communications 2023
Arora, Vipin et al.Capsaicin-induced depolymerization of axonal microtubules mediates analgesia for trigeminal neuropathic painPain2022
Li, Linxi et al.PCP Protein Inversin Regulates Testis Function Through Changes in Cytoskeletal Organization of Actin and MicrotubulesEndocrinology2022
Guerra San Juan, Irune et al.Loss of mouse Stmn2 function causes motor neuropathyNeuron2022
Damuka, Naresh et al.Initial Evaluations of the Microtubule-Based PET Radiotracer, [11C]MPC-6827 in a Rodent Model of Cocaine AbuseFrontiers in Medicine2022
Sun, Chiao Yin et al.LMBD1 protein participates in cell mitosis by regulating microtubule assemblyBiochemical Journal2021
Wu, Siwen et al.KIF15 supports spermatogenesis via its effects on Sertoli cell microtubule, actin, vimentin, and septin cytoskeletonsEndocrinology (United States)2021
Li, Huitao et al.NC1-Peptide from collagen α3 (IV) chains in the basement membrane of testes regulates spermatogenesis via p-FAK-Y407Endocrinology (United States)2020
Wen, Qing et al.Myosin VIIa supports spermatid/organelle transport and cell adhesion during spermatogenesis in the rat testisEndocrinology2019
Mao, Bai Ping et al.CaMSAP2 is a microtubule minus-end targeting protein that regulates BTB dynamics through cytoskeletal organizationEndocrinology2019
Eberle-Singh, Jaime A. et al.Effective delivery of a microtubule polymerization inhibitor synergizes with standard regimens in models of pancreatic ductal adenocarcinomaClinical Cancer Research2019
Su, Wenhui et al.Cdc42 is involved in NC1 peptide-regulated BTB dynamics through actin and microtubule cytoskeletal reorganizationFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019
Li, Linxi et al.Planar cell polarity protein Dishevelled 3 (Dvl3) regulates ectoplasmic specialization (ES) dynamics in the testis through changes in cytoskeletal organizationCell Death and Disease2019
Li, Lin Xi et al.Regulation of blood-testis barrier dynamics by the mTORC1/rpS6 signaling complex: An in vitro studyAsian Journal of Andrology2019
Wen, Qing et al.Actin nucleator Spire 1 is a regulator of ectoplasmic specialization in the testisCell Death and Disease2018
Wen, Qing et al.Dynein 1 supports spermatid transport and spermiation during spermatogenesis in the rat testisAmerican Journal of Physiology - Endocrinology and Metabolism2018
Zhang, Guanyi et al.Androgen receptor splice variants circumvent AR blockade by microtubule-targeting agentsOncotarget2015
Niesman, Ingrid R. et al.Caveolin isoform switching as a molecular, structural, and metabolic regulator of microgliaMolecular and Cellular Neuroscience2013
Fan, Jianguo et al.A role for γs-crystallin in the organization of actin and fiber cell maturation in the mouse lensFEBS Journal2012
Kapur, Mridu et al.Calcium tips the balance: A microtubule plus end to lattice binding switch operates in the carboxyl terminus of BPAG1n4EMBO Reports2012
Liu, Jian J. et al.A mechanism of Rap1-induced stabilization of endothelial cell-cell junctionsMolecular Biology of the Cell2011
Mourad, Nizar I. et al.Metabolic amplification of insulin secretion by glucose is independent of β-cell microtubulesAmerican journal of physiology. Cell physiology2011
Roth, Daniela Martino et al.Mechanism of microtubule-facilitated "fast track" nuclear importJournal of Biological Chemistry2011
Romero, Ana M. et al.Chronic ethanol exposure alters the levels, assembly, and cellular organization of the actin cytoskeleton and microtubules in hippocampal neurons in primary cultureToxicological Sciences2010
Moseley, Gregory W. et al.Dual modes of rabies P-protein association with microtubules: A novel strategy to suppress the antiviral responseJournal of Cell Science2009
Roth, Daniela Martino et al.A microtubule-facilitated nuclear import pathway for cancer regulatory proteinsTraffic2007
Rayala, Suresh K. et al.Dynamic interplay between nitration and phosphorylation of tubulin cofactor B in the control of microtubule dynamicsProceedings of the National Academy of Sciences of the United States of America2007
Davis, Francesca J. et al.Concurrent opposite effects of trichostatin A, an inhibitor of histone deacetylases, on expression of α-MHC and cardiac tubulins: Implication for gain in cardiac muscle contractilityAmerican Journal of Physiology - Heart and Circulatory Physiology2005
Reiter-Funk, Cindy K. et al.Chronic ethanol exposure increases microtubule content in PC12 cellsBMC Neuroscience2005
Vogl, Thomas et al.MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytesBlood2004

BK029: Microtubule Binding Protein Spin-Down Assay Biochem Kit

AuthorTitleJournalYearArticle Link
Höhler, Mona et al.Direct targeting of host microtubule and actin cytoskeletons by a chlamydial pathogenic effector proteinJournal of cell science2024
Verrillo, Giulia et al.Non-canonical role for the BAF complex subunit DPF3 in mitosis and ciliogenesisJournal of Cell Science2024
Chang, Chia Jung et al.The microtubule-dynamin binding inhibitor peptide PHDP5 rescues spatial learning and memory deficits in Alzheimer’s disease model miceBrain Research2024
Muhs, Stefanie et al.Centrosomal Protein 55 Regulates Chromosomal Instability in Cancer Cells by Controlling Microtubule DynamicsCells 2024
Ceglowski, Julia et al.TTLL12 is required for primary ciliary axoneme formation in polarized epithelial cellsEMBO Reports2024
Liu, Junnan et al.Impairment of α-tubulin and F-actin interactions of GJB3 induces aneuploidy in urothelial cells and promotes bladder cancer cell invasionCellular and Molecular Biology Letters2024
Ortmann, Simon et al.A conserved microtubule-binding region in Xanthomonas XopL is indispensable for induced plant cell death reactionsPLOS Pathogens2023
Mehta, Virja et al.SPECC1L binds the myosin phosphatase complex MYPT1/PP1β and can regulate its distribution between microtubules and filamentous actinJournal of Biological Chemistry2023
Adrian, Max et al.Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine releaseNature Communications2023
Wolf, Marc et al.S100A8/S100A9 Integrates F-Actin and Microtubule Dynamics to Prevent Uncontrolled Extravasation of LeukocytesBiomedicines2023
Ren, Xinyi et al.Hax1 regulate focal adhesion dynamics through IQGAP1Cell Communication and Signaling2023
Wang, Xue et al.Loss of ORP3 induces aneuploidy and promotes bladder cancer cell invasion through deregulated microtubule and actin dynamicsCellular and Molecular Life Sciences2023
Hori, Tetsuya et al.Microtubule assembly by tau impairs endocytosis and neurotransmission via dynamin sequestration in Alzheimer's disease synapse modeleLife2022
Woo, Jung AA et al.β-arrestin1 promotes tauopathy by transducing GPCR signaling, disrupting microtubules and autophagyLife science alliance2021
Grubisha, M. J. et al.MAP2 is differentially phosphorylated in schizophrenia, altering its functionMolecular Psychiatry 2021
Miquel, M. et al.Microtubule interaction of LICC1, a maize homologue of a component of the human muskelin/RanBPM/CTLH protein complexBiologia Plantarum2021
Huang, Ning et al.Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemiaCurrent Biology2021
Li, Yan et al.The domain of unknown function 4005 (DUF4005) in an Arabidopsis IQD protein functions in microtubule bindingJournal of Biological Chemistry2021
Wortzel, Inbal et al.Mitotic HOOK3 phosphorylation by ERK1c drives microtubule-dependent Golgi destabilization and fragmentationiScience2021
Ait-Bouziad, Nadine et al.Phosphorylation of the overlooked tyrosine 310 regulates the structure, aggregation, and microtubule- And lipid-binding properties of TauJournal of Biological Chemistry2020
Martinez, Pablo et al.TANGLED1 mediates microtubule interactions that may promote division plane positioning in maizeJournal of Cell Biology2020
Shih, Pu Yun et al.Autism-linked mutations of CTTNBP2 reduce social interaction and impair dendritic spine formation via diverse mechanismsActa neuropathologica communications2020
La, The Mon et al.Dynamin 1 is important for microtubule organization and stabilization in glomerular podocytesFASEB Journal2020
Kappelmann-Fenzl, Melanie et al.Complex formation with monomeric α-tubulin and importin 13 fosters c-jun protein stability and is required for c-jun’s nuclear translocation and activityCancers2019
Liang, Hong et al.The microtubule-associated protein IQ67 DOMAIN5 modulates microtubule dynamics and pavement cell shapePlant Physiology2018
Bajaj, Rakhi et al.KNL1 Binding to PP1 and Microtubules Is Mutually ExclusiveStructure2018
Pellacani, Claudia et al.Splicing factors Sf3A2 and Prp31 have direct roles in mitotic chromosome segregationeLife2018
Vasileva, Ekaterina et al.The role of microtubules in the regulation of epithelial junctionsTissue Barriers2018
Renna, Luciana et al.TGNap1 is required for microtubule-dependent homeostasis of a subpopulation of the plant trans-Golgi networkNature Communications2018
Perchey, R T et al.p27Kip1 regulates the microtubule bundling activity of PRC1… et Biophysica Acta (BBA …2018
Zhang, Xiang et al.Palladin is a novel microtubule-associated protein responsible for spindle orientationScientific Reports2017
Sun, Tao et al.JIP1 and JIP3 cooperate to mediate TrkB anterograde axonal transport by activating kinesin-1Cellular and Molecular Life Sciences2017
Golub, Ognjen et al.Activation of discs large by aPKC aligns the mitotic spindle to the polarity axis during asymmetric cell divisioneLife2017
Becher, Alexander et al.The armadillo protein p0071 controls KIF3 motor transportJournal of Cell Science2017
Liu, Zengyu et al.Cellulose-Microtubule Uncoupling Proteins Prevent Lateral Displacement of Microtubules during Cellulose Synthesis in ArabidopsisDevelopmental Cell2016
Wang, Peixiang et al.RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling EndosomesPLoS Genetics2016
Kim, Juri et al.Identification of a novel microtubule-binding protein in Giardia lambliaKorean Journal of Parasitology2016
Kesten, Christopher et al.In vitro Microtubule Binding Assay and Dissociation Constant EstimationBio-Protocol2016
Endler, Anne et al.A Mechanism for Sustained Cellulose Synthesis during Salt StressCell2015
Hamm, Matthew et al.Physiologically relevant factors influence tau phosphorylation by leucine-rich repeat kinase 2Journal of Neuroscience Research2015
Colbert, Paul L. et al.EphrinB1: Novel microtubule associated protein whose expression affects taxane sensitivityOncotarget2015
Kitagawa, Mayumi et al.Cdk1 coordinates timely activation of MKlp2 kinesin with relocation of the chromosome passenger complex for cytokinesisCell Reports2014
Rajgor, Dipen et al.Mammalian microtubule P-body dynamics are mediated by nesprin-1Journal of Cell Biology2014
Kim, Juri et al.Characterization of microtubule-binding and dimerization activity of Giardia lamblia end-binding 1 proteinPLoS ONE2014
Lee, Dongmin et al.Enhanced expression and purification of inositol 1,4,5-trisphosphate 3-kinase A through use of the pCold1-GST vector and a C-terminal hexahistidine tag in Escherichia coliProtein Expression and Purification2014
Shih, Pu Yun et al.Cortactin-binding protein 2 increases microtubule stability and regulates dendritic arborizationJournal of Cell Science2014
He, Ze et al.Cytoplasmic retention of a nucleocytoplasmic protein TBC1D3 by microtubule network is required for enhanced EGFR signalingPLoS ONE2014
Jiang, Hao et al.A Microtubule-Associated Zinc Finger Protein, BuGZ, Regulates Mitotic Chromosome Alignment by Ensuring Bub3 Stability and Kinetochore TargetingDevelopmental Cell2014
Alev, Cantas et al.Proteomic approaches for the study of electrical synapses and associated protein-interaction complexesNeuromethods2013
Zhu, Mei et al.MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progressionJournal of Cell Biology2013
Fugelstad, Johanna et al.Functional characterization of the pleckstrin homology domain of a cellulose synthase from the oomycete Saprolegnia monoicaBiochemical and biophysical research communications2012
Urbé, Sylvie et al.Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome-and microtubule-associated functionsMolecular Biology of the Cell2012
Lee, D et al.Inositol 1, 4, 5-Trisphosphate 3-Kinase A Is a Novel Microtubule-associated ProteinJournal of Biological …2012
Roth, Daniela Martino et al.Mechanism of microtubule-facilitated "fast track" nuclear importJournal of Biological Chemistry2011
Azakir, Bilal A. et al.Dysferlin interacts with tubulin and microtubules in mouse skeletal musclePLoS ONE2010
Nishi, Mayuko et al.Requirement for microtubule integrity in the SOCS1-mediated intracellular dynamics of HIV-1 GagFEBS Letters2009
Sackett, Dan L. et al.Intracellular proadrenomedullin-derived peptides decorate the microtubules and contribute to cytoskeleton functionEndocrinology2008
Moshnikova, Anna et al.Interaction of the growth and tumour suppressor NORE1A with microtubules is not required for its growth-suppressive functionBMC Research Notes2008
Cho, Hyekyung P. et al.The dual-specificity phosphatase CDC14B bundles and stabilizes microtubulesMolecular and cellular biology2005
Monzo, Pascale et al.Clues to CD2-associated protein involvement in cytokinesisMolecular Biology of the Cell2005
Lansbergen, Gideon et al.Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localizationThe Journal of Cell Biology2004
Yanagisawa, Masahiro et al.A Novel Interaction between Kinesin and p120 Modulates p120 Localization and FunctionJournal of Biological Chemistry2004
Kim, Kyung Tae et al.Function of Drg1/Rit42 in p53-dependent mitotic spindle checkpointJournal of Biological Chemistry2004
Goryunov, Dmitry et al.Studying cytolinker proteinsMethods in Cell Biology2004
Schmidt, Mirko H.H. et al.SETA/CIN85/Ruk and its binding partner AIP1 associate with diverse cytoskeletal elements, including FAKs, and modulate cell adhesionJournal of Cell Science2003
Pennetta, Giuseppa et al.Drosophila VAP-33A directs bouton formation at neuromuscular junctions in a dosage-dependent mannerNeuron2002
Nielsen, Finn C. et al.Cytoplasmic trafficking of IGF-II mRNA-binding protein by conserved KH domainsJournal of Cell Science2002
Ziegelbauer, Joseph et al.Transcription Factor MIZ-1 Is Regulated via Microtubule AssociationMolecular Cell2001

Live Cell Imaging

TL440M: Tubulin Protein (Fluorescent AMCA)

AuthorTitleJournalYearArticle Link
Robinson, Benjamin P. et al.Septin-coated microtubules promote maturation of multivesicular bodies by inhibiting their motilityJournal of Cell Biology2024
Kalra, Aarat P. et al.Electronic Energy Migration in MicrotubulesACS Central Science2023
Vandelinder, Virginia et al.Photodamage and the Importance of Photoprotection in Biomolecular-Powered Device ApplicationsAnalytical Chemistry2014
Cho, Sangyeon et al.Simple super-resolution live-cell imaging based on diffusion-assisted Förster resonance energy transferScientific Reports2013

TL488M: Tubulin Protein (Fluorescent HiLyte488)

AuthorTitleJournalYearArticle Link
Zhou, Qing et al.An orphan kinesin in Trypanosoma brucei regulates hook complex assembly and Golgi biogenesismBio2024
Sun, Shuangshuang et al.Metabolic regulation of cytoskeleton functions by HDAC6-catalyzed α-tubulin lactylationNature Communications 2024 15:12024
Salvador-Garcia, David et al.A force-sensitive mutation reveals a non-canonical role for dynein in anaphase progressionThe Journal of cell biology2024
Singh, Kashish et al.Molecular mechanism of dynein-dynactin complex assembly by LIS1Science2024
Rai, Dipti et al.CAMSAPs and nucleation-promoting factors control microtubule release from γ-TuRCNature Cell Biology2024
Polley, Soumitra et al. Stable kinetochore‐microtubule attachment requires loop‐dependent Ndc80‐Ndc80 binding The EMBO Journal2023
Nishida, Kohei et al.Effects of three microtubule-associated proteins (MAP2, MAP4, and Tau) on microtubules’ physical properties and neurite morphologyScientific Reports2023
De Abreu, Isadora Rocha et al.A molecular analysis of substituted phenylethylamines as potential microtubule targeting agents through in silico methods and in vitro microtubule-polymerization activityScientific Reports 2023
Singh, Rajendra K. et al.Coordinated Biophysical Stimulation of MSCs via Electromagnetized Au-Nanofiber Matrix Regulates Cytoskeletal-to-Nuclear Mechanoresponses and Lineage SpecificationAdvanced Functional Materials2023
Castrogiovanni, Cédric et al.Evidence for a HURP/EB free mixed-nucleotide zone in kinetochore-microtubulesNature Communications2022
Masucci, Erin M. et al.Microtubule dynamics influence the retrograde biased motility of kinesin-4 motor teams in neuronal dendritesMolecular Biology of the Cell2022
Henty-Ridilla, Jessica L.Visualizing Actin and Microtubule Coupling Dynamics In Vitro by Total Internal Reflection Fluorescence (TIRF) MicroscopyJoVE (Journal of Visualized Experiments)2022
Sasanpour, Mehrzad et al.Reconstituting and Characterizing Actin-Microtubule Composites with Tunable Motor-Driven Dynamics and MechanicsJoVE (Journal of Visualized Experiments)2022
Baron, Desiree M et al.ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function.Cell reports2022
Cheng, Xianrui et al.Xenopus laevis egg extract preparation and live imaging methods for visualizing dynamic cytoplasmic organizationJournal of Visualized Experiments2021
Goldstein-Levitin, Alina et al.Intracellular functions and motile properties of bi-directional kinesin-5 cin8 are regulated by neck linker dockingeLife2021
Lee, Gloria et al.Active cytoskeletal composites display emergent tunable contractility and restructuringSoft Matter2021
Aher, Amol et al.CLASP Mediates Microtubule Repair by Restricting Lattice Damage and Regulating Tubulin IncorporationCurrent Biology2020
Nolet, Felix E. et al.Nuclei determine the spatial origin of mitotic waveseLife2020
Chen, Keyu et al.Giant ankyrin-B suppresses stochastic collateral axon branching through direct interaction with microtubulesJournal of Cell Biology2020
Rodríguez-García, Ruddi et al.Mechanisms of Motor-Independent Membrane Remodeling Driven by Dynamic MicrotubulesCurrent Biology2020
Farhadi, Leila et al.Actin and microtubule crosslinkers tune mobility and control co-localization in a composite cytoskeletal networkSoft Matter2020
Nakos, Konstantinos et al.Regulation of microtubule plus end dynamics by septin 9Cytoskeleton2019
Guedes-Dias, Pedro et al.Kinesin-3 Responds to Local Microtubule Dynamics to Target Synaptic Cargo Delivery to the PresynapseCurrent Biology2019
Nakos, Konstantinos et al.Septin 2/6/7 complexes tune microtubule plus-end growth and EB1 binding in a concentration- And filament-dependent mannerMolecular Biology of the Cell2019
Fan, Yuanwei et al.The Arabidopsis SPIRAL2 Protein Targets and Stabilizes Microtubule Minus EndsCurrent Biology2018
Colin, Alexandra et al.Actin-Network Architecture Regulates Microtubule DynamicsCurrent Biology2018
McClintock, Mark A. et al.RNA-directed activation of cytoplasmic dynein-1 in reconstituted transport RNPseLife2018
Aher, Amol et al.CLASP Suppresses Microtubule Catastrophes through a Single TOG DomainDevelopmental Cell2018
Melo, Esther et al.HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease ModelEBioMedicine2018
Zhu, Yili et al.An in vitro Microscopy-based Assay for Microtubule-binding and Microtubule-crosslinking by Budding Yeast Microtubule-associated ProteinBio-Protocol2018
Zhang, Rui et al.Interplay of structure, elasticity, and dynamics in actin-based nematic materialsProceedings of the National Academy of Sciences of the United States of America2017
Kandel, Mikhail E. et al.Label-Free Imaging of Single Microtubule Dynamics Using Spatial Light Interference MicroscopyACS Nano2017
Arellano-Santoyo, Hugo et al.A Tubulin Binding Switch Underlies Kip3/Kinesin-8 Depolymerase ActivityDevelopmental Cell2017
Britto, Mishan et al.Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanismProceedings of the National Academy of Sciences of the United States of America2016
Taberner, Núria et al.Reconstituting Functional Microtubule-Barrier InteractionsMethods in Cell Biology2014
DeBerg, Hannah A. et al.Motor domain phosphorylation modulates kinesin-1 transportJournal of Biological Chemistry2013
Rostovtseva, Tatiana K. et al.Membrane Lipid Composition Regulates Tubulin Interaction with Mitochondrial Voltage-dependent Anion Channel *Journal of Biological Chemistry2012
Hara, Masatoshi et al.Greatwall kinase and cyclin B-Cdk1 are both critical constituents of M-phase-promoting factorNature Communications2012

TL590M: Tubulin Protein (Rhodamine)

AuthorTitleJournalYearArticle Link
Zhou, Qing et al.An orphan kinesin in Trypanosoma brucei regulates hook complex assembly and Golgi biogenesismBio2024
Sun, Shuangshuang et al.Metabolic regulation of cytoskeleton functions by HDAC6-catalyzed α-tubulin lactylationNature Communications 2024 15:12024
Lucas, Lathan et al.Alternatively Spliced MAP4 Isoforms Have Key Roles in Maintaining Microtubule Organization and Skeletal Muscle FunctioniScience2024
Queen, Katelyn A. et al.Modification of the neck-linker of KIF18A alters Microtubule subpopulation preferenceMolecular biology of the cell2024
Muhs, Stefanie et al.Centrosomal Protein 55 Regulates Chromosomal Instability in Cancer Cells by Controlling Microtubule DynamicsCells 2024
Luchniak, Anna et al.Tubulin CFEOM mutations both inhibit or activate kinesin motor activityMolecular Biology of the Cell2024
Fan, Yuanwei et al.A divergent tumor overexpressed gene domain and oligomerization contribute to SPIRAL2 function in stabilizing microtubule minus endsThe Plant Cell2024
Liu, Xinglei et al.Kinesin-14 HSET and KlpA are non-processive microtubule motors with load-dependent power strokesNature Communications2024
Mahalingan, Kishore K. et al.Structural basis for α-tubulin-specific and modification state-dependent glutamylationNature Chemical Biology2024
Chauhan, Prashali et al.Ionic strength alters crosslinker-driven self-organization of microtubulesCytoskeleton2024
Jijumon, A. S. et al.A Platform for Medium-Throughput Cell-Free Analyses of Microtubule-Interacting Proteins Using Mammalian Cell LysatesCurrent Protocols2024
Hu, Huiqing et al.A kinesin-13 family kinesin in Trypanosoma brucei regulates cytokinesis and cytoskeleton morphogenesis by promoting microtubule bundlingPLOS Pathogens2024
Gluszek‐Kustusz, Agata et al. Phosphorylation controls spatial and temporal activities of motor‐PRC1 complexes to complete mitosis The EMBO Journal2023
Memarian, Fereshteh L. et al.Forming, Confining, and Observing Microtubule-Based Active NematicsJournal of Visualized Experiments (JoVE)2023
van den Berg, Cyntha M. et al.CSPP1 stabilizes growing microtubule ends and damaged lattices from the luminal sideJournal of Cell Biology2023
McGorty, Ryan J. et al.Kinesin and myosin motors compete to drive rich multiphase dynamics in programmable cytoskeletal compositesPNAS Nexus2023
Nithianantham, Stanley et al.The kinesin-5 tail and bipolar minifilament domains are the origin of its microtubule crosslinking and sliding activityMolecular biology of the cell2023
McHugh, Toni et al.Potent microtubule-depolymerizing activity of a mitotic Kif18b–MCAK–EB networkJournal of Cell Science2023
Yang, Shuzhen et al.EB1 decoration of microtubule lattice facilitates spindle-kinetochore lateral attachment in Plasmodium male gametogenesisNature Communications2023
Hoshino, Asumi et al.The microtubule-severing protein UNC-45A preferentially binds to curved microtubules and counteracts the microtubule-straightening effects of TaxolJournal of Biological Chemistry2023
Oda, Haruka et al.Actin filaments accumulated in the nucleus remain in the vicinity of condensing chromosomes in the zebrafish early embryoBiology Open2023
Palumbo, Jacob et al.Directly Measuring Forces Within Reconstituted Active Microtubule BundlesJoVE (Journal of Visualized Experiments)2022
Qian, Pengge et al.Apical anchorage and stabilization of subpellicular microtubules by apical polar ring ensures Plasmodium ookinete infection in mosquitoNature Communications 2022
Henty-Ridilla, Jessica L.Visualizing Actin and Microtubule Coupling Dynamics In Vitro by Total Internal Reflection Fluorescence (TIRF) MicroscopyJoVE (Journal of Visualized Experiments)2022
Sasanpour, Mehrzad et al.Reconstituting and Characterizing Actin-Microtubule Composites with Tunable Motor-Driven Dynamics and MechanicsJoVE (Journal of Visualized Experiments)2022
Planelles-Herrero, Vicente Jose et al.Elongator stabilizes microtubules to control central spindle asymmetry and polarized trafficking of cell fate determinantsNature Cell Biology 2022
Kuzmić, Mira et al.Septin-microtubule association via a motif unique to isoform 1 of septin 9 tunes stress fibersJournal of Cell Science2022
Lee, Gloria et al.Myosin-driven actin-microtubule networks exhibit self-organized contractile dynamicsScience Advances2021
Hough, Cameron M. et al.Disassembly of microtubules by intense terahertz pulsesBiomedical Optics Express2021
Habicht, Juri et al.UNC-45A breaks the microtubule lattice independently of its effects on non-muscle myosin IIJournal of Cell Science2021
Kundu, Tanushree et al.Coupling of dynamic microtubules to F-actin by Fmn2 regulates chemotaxis of neuronal growth conesJournal of Cell Science2021
Saper, Gadiel et al.Robotic end-to-end fusion of microtubules powered by kinesinScience Robotics2021
Alfieri, Angus et al.Two modes of PRC1-mediated mechanical resistance to kinesin-driven microtubule network disruptionCurrent Biology2021
Kaur, Simranpreet et al.Expansion of the phenotypic spectrum of de novo missense variants in kinesin family member 1A (KIF1A)Human Mutation2020
Ricketts, Shea N. et al.Triggering Cation-Induced Contraction of Cytoskeleton Networks via MicrofluidicsFrontiers in Physics2020
Pyrpassopoulos, Serapion et al.Modulation of Kinesin’s Load-Bearing Capacity by Force Geometry and the Microtubule TrackBiophysical Journal2020
Aher, Amol et al.CLASP Mediates Microtubule Repair by Restricting Lattice Damage and Regulating Tubulin IncorporationCurrent Biology2020
Chen, Keyu et al.Giant ankyrin-B suppresses stochastic collateral axon branching through direct interaction with microtubulesJournal of Cell Biology2020
Rodríguez-García, Ruddi et al.Mechanisms of Motor-Independent Membrane Remodeling Driven by Dynamic MicrotubulesCurrent Biology2020
Saper, Gadiel et al.Kinesin-propelled label-free microtubules imaged with interference reflection microscopyNew Journal of Physics2020
Adriaans, Ingrid E. et al.MKLP2 Is a Motile Kinesin that Transports the Chromosomal Passenger Complex during AnaphaseCurrent Biology2020
Gaska, Ignas et al.The Mitotic Crosslinking Protein PRC1 Acts Like a Mechanical Dashpot to Resist Microtubule SlidingDevelopmental Cell2020
Kalra, Aarat P. et al.Investigation of the electrical properties of microtubule ensembles under cell-like conditionsNanomaterials2020
Tuszynski, Jack A. et al.Microtubules as Sub-Cellular MemristorsScientific Reports2020
Francis, Madison L. et al.Non-monotonic dependence of stiffness on actin crosslinking in cytoskeleton compositesSoft Matter2019
Leong, Su Ling et al.Reconstitution of Microtubule Nucleation In Vitro Reveals Novel Roles for Mzt1Current Biology2019
Lopes, Joseph et al.Membrane mediated motor kinetics in microtubule gliding assaysScientific Reports2019
Faltova, Lenka et al.Crystal Structure of a Heterotetrameric Katanin p60:p80 ComplexStructure2019
Grueb, Saskia S. et al.The formin Drosophila homologue of Diaphanous2 (Diaph2) controls microtubule dynamics in colorectal cancer cells independent of its FH2-domainScientific Reports2019
Chudinova, Elena M. et al.On the interaction of ribosomal protein RPL22e with microtubulesCell Biology International2019
Fu, Meng meng et al.The Golgi Outpost Protein TPPP Nucleates Microtubules and Is Critical for MyelinationCell2019
Ricketts, Shea N. et al.Varying crosslinking motifs drive the mesoscale mechanics of actin-microtubule compositesScientific Reports2019
Nakos, Konstantinos et al.Septin 2/6/7 complexes tune microtubule plus-end growth and EB1 binding in a concentration- And filament-dependent mannerMolecular Biology of the Cell2019
Karasmanis, Eva P. et al.Erratum: Polarity of Neuronal Membrane Traffic Requires Sorting of Kinesin Motor Cargo during Entry into Dendrites by a Microtubule-Associated Septin (Developmental Cell (2018) 46(2) (204–218.e7), (S1534580718304982) (10.1016/j.devcel.2018.06.013))Developmental Cell2018
Ganguly, Anindya et al.Importin-β Directly Regulates the Motor Activity and Turnover of a Kinesin-4Developmental Cell2018
Fan, Yuanwei et al.The Arabidopsis SPIRAL2 Protein Targets and Stabilizes Microtubule Minus EndsCurrent Biology2018
Romé, Pierre et al.A novel microtubule nucleation pathway for meiotic spindle assembly in oocytesJournal of Cell Biology2018
Colin, Alexandra et al.Actin-Network Architecture Regulates Microtubule DynamicsCurrent Biology2018
Rao, Lu et al.Combining structure–function and single-molecule studies on cytoplasmic dyneinMethods in Molecular Biology2018
Aher, Amol et al.CLASP Suppresses Microtubule Catastrophes through a Single TOG DomainDevelopmental Cell2018
Hilton, Nicholas A. et al.Identification of TOEFAZ1-interacting proteins reveals key regulators of Trypanosoma brucei cytokinesisMolecular Microbiology2018
Höing, Susanne et al.Dynarrestin, a Novel Inhibitor of Cytoplasmic DyneinCell Chemical Biology2018
Reinemann, Dana N. et al.Processive Kinesin-14 HSET Exhibits Directional Flexibility Depending on Motor TrafficCurrent Biology2018
Ricketts, Shea N. et al.Co-Entangled Actin-Microtubule Composites Exhibit Tunable Stiffness and Power-Law Stress RelaxationBiophysical Journal2018
Zhu, Yili et al.An in vitro Microscopy-based Assay for Microtubule-binding and Microtubule-crosslinking by Budding Yeast Microtubule-associated ProteinBio-Protocol2018
Murray, John W. et al.Reduction of organelle motility by removal of potassium and other solutesPLoS ONE2017
Shim, Albert et al.Gliding Assay to Analyze Microtubule-based Motor Protein DynamicsBio-Protocol2017
Arellano-Santoyo, Hugo et al.A Tubulin Binding Switch Underlies Kip3/Kinesin-8 Depolymerase ActivityDevelopmental Cell2017
Reinemann, Dana N. et al.Collective Force Regulation in Anti-parallel Microtubule Gliding by Dimeric Kif15 Kinesin MotorsCurrent Biology2017
Britto, Mishan et al.Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanismProceedings of the National Academy of Sciences of the United States of America2016
Shapira, Ofer et al.Motile properties of the bi-directional kinesin-5 Cin8 are affected by phosphorylation in its motor domainScientific Reports2016
Zitouni, Sihem et al.CDK1 Prevents Unscheduled PLK4-STIL Complex Assembly in Centriole BiogenesisCurrent Biology2016
Bartsch, Tobias F. et al.Nanoscopic imaging of thick heterogeneous soft-matter structures in aqueous solutionNature Communications2016
Kim, Kyongwan et al.Electric field-induced reversible trapping of microtubules along metallic glass microwire electrodesJournal of Applied Physics2015
Szyk, Agnieszka et al.Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferaseCell2014
Volkov, Vladimir A. et al.Preparation of segmented microtubules to study motions driven by the disassembling microtubule endsJournal of Visualized Experiments2014
Kitagawa, Mayumi et al.Cdk1 coordinates timely activation of MKlp2 kinesin with relocation of the chromosome passenger complex for cytokinesisCell Reports2014
Hawkins, Taviare L. et al.Mechanical properties of doubly stabilized microtubule filamentsBiophysical Journal2013
McVicker, Derrick P. et al.The nucleotide-binding state of microtubules modulates kinesin processivity and the ability of Tau to inhibit kinesin-mediated transportJournal of Biological Chemistry2011
Mori, Masashi et al.Intracellular Transport by an Anchored Homogeneously Contracting F-Actin MeshworkCurrent Biology2011
Mukhopadhyay, Aparna et al.Proteomic analysis of endocytic vesicles: Rab1a regulates motility of early endocytic vesiclesJournal of Cell Science2011

TL620M: Tubulin Protein (X-rhodamine)

AuthorTitleJournalYearArticle Link
Liu, Tianyang et al.Mechanochemical tuning of a kinesin motor essential for malaria parasite transmissionNature Communications 2022
Gibson, James M et al.Coil-to-α-helix transition at the Nup358-BicD2 interface activates BicD2 for dynein recruitmenteLife2022
Cook, Alexander D. et al.Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibitionJournal of Biological Chemistry2021
Qiu, Rongde et al.Dynein activation in vivo is regulated by the nucleotide states of its AAA3 domainCurrent Biology2021
Zhernov, Ilia et al.Intrinsically Disordered Domain of Kinesin-3 Kif14 Enables Unique Functional DiversityCurrent Biology2020
McElmurry, Kristi et al.Dynein-mediated microtubule translocation powering neurite outgrowth in chick and Aplysia neurons requires microtubule assemblyJournal of Cell Science2020
Peña, Alejandro et al.Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron MicroscopyStructure2020
Nakos, Konstantinos et al.Regulation of microtubule plus end dynamics by septin 9Cytoskeleton2019
Jiang, Shuo et al.Interplay between the Kinesin and Tubulin Mechanochemical Cycles Underlies Microtubule Tip Tracking by the Non-motile Ciliary Kinesin Kif7Developmental Cell2019
Sladewski, Thomas E. et al.Recruitment of two dyneins to an mRNA-dependent bicaudal D transport complexeLife2018
Haase, Julian et al.Distinct Roles of the Chromosomal Passenger Complex in the Detection of and Response to Errors in Kinetochore-Microtubule AttachmentDevelopmental Cell2017
Maciejowski, John et al.Mps1 Regulates Kinetochore-Microtubule Attachment Stability via the Ska Complex to Ensure Error-Free Chromosome SegregationDevelopmental Cell2017
Leslie, Kris et al.Going Solo: Measuring the motions of microtubules with an in vitro assay for tirf microscopy.Methods in Cell Biology2013

TL670M: Tubulin Protein (Fluorescent HiLyte 647)

AuthorTitleJournalYearArticle Link
Robinson, Benjamin P. et al.Septin-coated microtubules promote maturation of multivesicular bodies by inhibiting their motilityJournal of Cell Biology2024
Xu, Yixin et al.Partial closure of the γ-tubulin ring complex by CDK5RAP2 activates microtubule nucleationDevelopmental Cell2024
Takagishi, Maki et al.Motor protein Kif6 regulates cilia motility and polarity in brain ependymal cellsDMM Disease Models and Mechanisms2024
Seo, Dahee et al.Poxvirus A51R Proteins Negatively Regulate Microtubule-Dependent Transport by Kinesin-1International Journal of Molecular Sciences2024
Rai, Dipti et al.CAMSAPs and nucleation-promoting factors control microtubule release from γ-TuRCNature Cell Biology2024
Aquino-Perez, Cecilia et al.FAM110A promotes mitotic spindle formation by linking microtubules with actin cytoskeletonProceedings of the National Academy of Sciences2024
Nithianantham, Stanley et al.The kinesin-5 tail and bipolar minifilament domains are the origin of its microtubule crosslinking and sliding activityMolecular biology of the cell2023
McHugh, Toni et al.Potent microtubule-depolymerizing activity of a mitotic Kif18b–MCAK–EB networkJournal of Cell Science2023
Tsukita, Kazuto et al.Phase separation of an actin nucleator by junctional microtubules regulates epithelial functionScience Advances2023
Palumbo, Jacob et al.Directly Measuring Forces Within Reconstituted Active Microtubule BundlesJoVE (Journal of Visualized Experiments)2022
Havelka, Daniel et al.Lab-on-chip microscope platform for electro-manipulation of a dense microtubules networkScientific Reports2022
Tsitkov, Stanislav et al.The rate of microtubule breaking increases exponentially with curvatureScientific Reports 2022
Castrogiovanni, Cédric et al.Evidence for a HURP/EB free mixed-nucleotide zone in kinetochore-microtubulesNature Communications2022
Henty-Ridilla, Jessica L.Visualizing Actin and Microtubule Coupling Dynamics In Vitro by Total Internal Reflection Fluorescence (TIRF) MicroscopyJoVE (Journal of Visualized Experiments)2022
Planelles-Herrero, Vicente Jose et al.Elongator stabilizes microtubules to control central spindle asymmetry and polarized trafficking of cell fate determinantsNature Cell Biology 2022
Hochmair, Janine et al.Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensatesThe EMBO Journal2022
Havelka, Daniel et al.Lab-on-chip microscope platform for electro-manipulation of a dense microtubules networkScientific Reports2022
Watson, Joseph L. et al.High-efficacy subcellular micropatterning of proteins using fibrinogen anchorsJournal of Cell Biology2021
Cheng, Xianrui et al.Xenopus laevis egg extract preparation and live imaging methods for visualizing dynamic cytoplasmic organizationJournal of Visualized Experiments2021
Saper, Gadiel et al.Robotic end-to-end fusion of microtubules powered by kinesinScience Robotics2021
Diwaker, Drishya et al.Deletion of the Pseudorabies virus gE/gI-US9p complex disrupts kinesin KIF1A and KIF5C recruitment during egress, and alters the properties of microtubule-dependent transport in vitroPLoS Pathogens2020
Aher, Amol et al.CLASP Mediates Microtubule Repair by Restricting Lattice Damage and Regulating Tubulin IncorporationCurrent Biology2020
Tseng, Kuo Fu et al.The Tail of Kinesin-14a in Giardia Is a Dual Regulator of MotilityCurrent Biology2020
Bassir Kazeruni, Neda M. et al.Microtubule Detachment in Gliding Motility Assays Limits the Performance of Kinesin-Driven Molecular ShuttlesLangmuir2020
Rodríguez-García, Ruddi et al.Mechanisms of Motor-Independent Membrane Remodeling Driven by Dynamic MicrotubulesCurrent Biology2020
Gaska, Ignas et al.The Mitotic Crosslinking Protein PRC1 Acts Like a Mechanical Dashpot to Resist Microtubule SlidingDevelopmental Cell2020
Zehr, Elena A. et al.Katanin Grips the β-Tubulin Tail through an Electropositive Double Spiral to Sever MicrotubulesDevelopmental Cell2020
von Appen, Alexander et al.LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformationNature2020
Farhadi, Leila et al.Actin and microtubule crosslinkers tune mobility and control co-localization in a composite cytoskeletal networkSoft Matter2020
Nakos, Konstantinos et al.Regulation of microtubule plus end dynamics by septin 9Cytoskeleton2019
Guedes-Dias, Pedro et al.Kinesin-3 Responds to Local Microtubule Dynamics to Target Synaptic Cargo Delivery to the PresynapseCurrent Biology2019
Kazeruni, Neda M.Bassir et al.Assembling molecular shuttles powered by reversibly attached kinesinsJournal of Visualized Experiments2019
Siddiqui, Nida et al.PTPN21 and Hook3 relieve KIF1C autoinhibition and activate intracellular transportNature Communications2019
Jiang, Shuo et al.Interplay between the Kinesin and Tubulin Mechanochemical Cycles Underlies Microtubule Tip Tracking by the Non-motile Ciliary Kinesin Kif7Developmental Cell2019
Li, Feiran et al.Local direction change of surface gliding microtubulesBiotechnology and Bioengineering2019
Nakos, Konstantinos et al.Septin 2/6/7 complexes tune microtubule plus-end growth and EB1 binding in a concentration- And filament-dependent mannerMolecular Biology of the Cell2019
Karasmanis, Eva P. et al.Erratum: Polarity of Neuronal Membrane Traffic Requires Sorting of Kinesin Motor Cargo during Entry into Dendrites by a Microtubule-Associated Septin (Developmental Cell (2018) 46(2) (204–218.e7), (S1534580718304982) (10.1016/j.devcel.2018.06.013))Developmental Cell2018
Colin, Alexandra et al.Actin-Network Architecture Regulates Microtubule DynamicsCurrent Biology2018
Wang, Pan et al.The Central Stalk Determines the Motility of Mitotic Kinesin-14 HomodimersCurrent Biology2018
Aher, Amol et al.CLASP Suppresses Microtubule Catastrophes through a Single TOG DomainDevelopmental Cell2018
McIntosh, Betsy B. et al.Opposing Kinesin and Myosin-I Motors Drive Membrane Deformation and Tubulation along Engineered Cytoskeletal NetworksCurrent Biology2018
Pesenti, Marion E. et al.Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80Molecular Cell2018
Chen, Yang et al.Visualizing Autophagic Lysosome Reformation in Cells Using In Vitro Reconstitution SystemsCurrent Protocols in Cell Biology2018
Arellano-Santoyo, Hugo et al.A Tubulin Binding Switch Underlies Kip3/Kinesin-8 Depolymerase ActivityDevelopmental Cell2017
Gramlich, Michael W. et al.Single molecule investigation of kinesin-1 motility using engineered microtubule defectsScientific Reports2017
Maciejowski, John et al.Mps1 Regulates Kinetochore-Microtubule Attachment Stability via the Ska Complex to Ensure Error-Free Chromosome SegregationDevelopmental Cell2017
Zhang, Kai et al.Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and ActivatedCell2017
Britto, Mishan et al.Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanismProceedings of the National Academy of Sciences of the United States of America2016
DeBruhl, Heather et al.Rop, the Sec1/Munc18 homolog in Drosophila, is required for furrow ingression and stable cell shape during cytokinesisJournal of Cell Science2016
Dumont, Emmanuel L.P. et al.Molecular wear of microtubules propelled by surface-adhered kinesinsNature Nanotechnology 2015
Norris, Stephen R. et al.Influence of fluorescent tag on the motility properties of kinesin-1 in single-molecule assaysBiophysical Journal2015
Hara, Yuki et al.Dynein-Based Accumulation of Membranes Regulates Nuclear Expansion in Xenopus laevis Egg ExtractsDevelopmental Cell2015
Roth-Johnson, Elizabeth A. et al.Interaction between microtubules and the drosophila formin cappuccino and its effect on actin assemblyJournal of Biological Chemistry2014
Leslie, Kris et al.Going Solo: Measuring the motions of microtubules with an in vitro assay for tirf microscopy.Methods in Cell Biology2013

CY-SC002: SiR-Tubulin Kit

AuthorTitleJournalYearArticle Link
Huang, Jo Hsi et al.Robust trigger wave speed in Xenopus cytoplasmic extractsNature Communications 2024 15:12024
Li, Diyin et al.Bacterial toxins induce non-canonical migracytosis to aggravate acute inflammationCell Discovery 2024 10:12024
Tran, Minh Thi et al.Morphological Changes of 3T3 Cells under Simulated MicrogravityCells2024
Hueschen, Christina L. et al.Emergent actin flows explain distinct modes of gliding motilityNature Physics 20242024
Becker, Isabelle C. et al.Cell cycle–dependent centrosome clustering precedes proplatelet formationScience Advances2024
Hirashima, Tsuyoshi et al.ERK-mediated curvature feedback regulates branching morphogenesis in lung epithelial tissueCurrent Biology2024
Hou, Yiwei et al.Multi-resolution analysis enables fidelity-ensured deconvolution for fluorescence microscopyeLight2024
Chen, Ye et al.Dynamic nanomechanical characterization of cells in exosome therapyMicrosystems & Nanoengineering 2024
Joseph, Ivor et al.RAB11A and RAB11B control mitotic spindle function in intestinal epithelial progenitor cellsEMBO reports2023
Sanchini, Caterina et al.Protocol for observing microtubules and microtubule ends in both fixed and live primary microglia cellsSTAR Protocols2023
Richter, Manuela et al.Kinetochore-fiber lengths are maintained locally but coordinated globally by poles in the mammalian spindleeLife2023
Dang, David et al.Deep learning techniques and mathematical modeling allow 3D analysis of mitotic spindle dynamicsThe Journal of cell biology2023
Dunkley, Sam et al.Actin limits egg aneuploidies associated with female reproductive agingScience Advances2023
Alvelid, Jonatan et al.Event-triggered STED imagingNature Methods 2022 19:102022
Králová, J et al.Sterolight as imaging tool to study sterol uptake, trafficking and efflux in living cellsScientific Reports2022
Dema, Alessandro et al.Optogenetic EB1 inactivation shortens metaphase spindles by disrupting cortical force-producing interactions with astral microtubulesCurrent Biology2022
Kemble, Samuel et al.Analysis of Preplatelets and Their Barbell Platelet Derivatives by Imaging Flow CytometryBlood Advances2022
Safieddine, Adham et al.A choreography of centrosomal mRNAs reveals a conserved localization mechanism involving active polysome transportNature Communications 2021 12:12021
Scherer, Katharina M. et al.A fluorescent reporter system enables spatiotemporal analysis of host cell modification during herpes simplex virus-1 replication2021
Tsuchiya, Kenta et al.Ran-GTP Is Non-essential to Activate NuMA for Mitotic Spindle-Pole Focusing but Dynamically Polarizes HURP Near ChromosomesCurrent Biology2021
Kalargyrou, Aikaterini A et al.Nanotube‐like processes facilitate material transfer between photoreceptorsEMBO reports2021
Watson, Joseph L. et al.High-efficacy subcellular micropatterning of proteins using fibrinogen anchorsJournal of Cell Biology2021
Ho, Chi Nguyen Quynh et al.Simulated Microgravity Inhibits the Proliferation of Chang Liver Cells by Attenuation of the Major Cell Cycle Regulators and Cytoskeletal ProteinsInternational Journal of Molecular Sciences 2021, Vol. 22, Page 45502021
Gurianov, D. S. et al.PH domain of BCR provides colocalization of full-length BCR with centrosome together with cortactin to facilitate actin-organizing functionBiopolymers and Cell2021
Fiege, Jessica K. et al.Single cell resolution of SARS-CoV-2 tropism, antiviral responses, and susceptibility to therapies in primary human airway epitheliumPLOS Pathogens2021
Wolf, Bas de et al.Chromosomal instability by mutations in the novel minor spliceosome component CENATACThe EMBO Journal2021
Siddiqui, Sana et al.Epithelial miR-141 regulates IL-13–induced airway mucus productionJCI Insight2021
Blengini, Cecilia S. et al.Aurora kinase A is essential for meiosis in mouse oocytesPLOS Genetics2021
Hao, Kai et al.Cilia locally synthesize proteins to sustain their ultrastructure and functionsNature Communications2021
Miao, Shumin et al.DIAPH1 regulates chromosomal instability of cancer cells by controlling microtubule dynamicsEuropean Journal of Cell Biology2021
Singh, Divya et al.Destabilization of Long Astral Microtubules via Cdk1-Dependent Removal of GTSE1 from Their Plus Ends Facilitates Prometaphase Spindle OrientationCurrent Biology2021
Buijs, Robin R. et al.WDR47 protects neuronal microtubule minus ends from katanin-mediated severingCell Reports2021
Hoffmann, Patrick C. et al.Electron cryo-tomography reveals the subcellular architecture of growing axons in human brain organoidseLife2021
Jagrić, Mihaela et al.Optogenetic control of prc1 reveals its role in chromosome alignment on the spindle by overlap length-dependent forceseLife2021
Chinen, Takumi et al.Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assemblyJournal of Cell Biology2021
Quidwai, Tooba et al.A WDR35-dependent coat protein complex transports ciliary membrane cargo vesicles to ciliaeLife2021
Klemm, Lucas C. et al.Centriole and Golgi microtubule nucleation are dispensable for the migration of human neutrophil-like cellsMolecular Biology of the Cell2021
Zhao, Huijie et al.Fibrogranular materials function as organizers to ensure the fidelity of multiciliary assemblyNature Communications2021
Ordureau, Alban et al.Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagyMolecular Cell2021
Schiweck, Juliane et al.Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane traffickingNature Communications2021
Vukušić, Kruno et al.Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongationDevelopmental Cell2021
Lv, Qi et al.RNA-binding protein SORBS2 suppresses clear cell renal cell carcinoma metastasis by enhancing MTUS1 mRNA stabilityCell Death & Disease 2020 11:122020
Tabdanov, Erdem D. et al.Engineering Elastic Nano- and Micro-Patterns and Textures for Directed Cell MotilitySTAR Protocols2020
Ueki, Hiroshi et al.Multicolor two-photon imaging of in vivo cellular pathophysiology upon influenza virus infection using the two-photon IMPRESSNature Protocols2020
Park, Yeonkyoung et al.Nonsense-mediated mRNA decay factor UPF1 promotes aggresome formationNature Communications2020
Drutovic, David et al. Ran GTP and importin β regulate meiosis I spindle assembly and function in mouse oocytes The EMBO Journal2020
Cao, Yujie et al.Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule OrganizationCurrent Biology2020
Afanzar, Oshri et al.The nucleus serves as the pacemaker for the cell cycleeLife2020
Chinen, Takumi et al. Nu MA assemblies organize microtubule asters to establish spindle bipolarity in acentrosomal human cells The EMBO Journal2020
Hégarat, Nadia et al.Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin BThe EMBO Journal2020
Tona, Yosuke et al.Live imaging of hair bundle polarity acquisition demonstrates a critical timeline for transcription factor EMX2eLife2020
Domart, Florelle et al.Correlating sted and synchrotron xrf nano-imaging unveils cosegregation of metals and cytoskeleton proteins in dendriteseLife2020
Stiff, Tom et al.Prophase-Specific Perinuclear Actin Coordinates Centrosome Separation and Positioning to Ensure Accurate Chromosome SegregationCell Reports2020
Frontalini, F. et al.Foraminiferal Ultrastructure: A perspective From Fluorescent and Fluorogenic ProbesJournal of Geophysical Research: Biogeosciences2019
Dudka, Damian et al.Spindle-Length-Dependent HURP Localization Allows Centrosomes to Control Kinetochore-Fiber Plus-End DynamicsCurrent Biology2019
Wagner, Fabienne et al.Armadillo repeat-containing protein 1 is a dual localization protein associated with mitochondrial intermembrane space bridging complexPLoS ONE2019
Hu, Junyan et al.Distinct roles of two myosins in C. Elegans spermatid differentiationPLoS Biology2019
Drpic, Danica et al.Chromosome Segregation Is Biased by Kinetochore SizeCurrent Biology2018
Nguyen, Alexandra L. et al.Genetic Interactions between the Aurora Kinases Reveal New Requirements for AURKB and AURKC during Oocyte MeiosisCurrent Biology2018
Khatri, Natasha et al.The autism protein Ube3A/E6AP remodels neuronal dendritic arborization via caspase-dependent microtubule destabilizationJournal of Neuroscience2018
Larsson, Veronica J. et al.Mitotic spindle assembly and γ-tubulin localisation depend on the integral nuclear membrane protein Samp1Journal of Cell Science2018
Du Toit, André et al.The precision control of autophagic flux and vesicle dynamics—A micropattern approachCells2018
Bennabi, Isma et al.Shifting meiotic to mitotic spindle assembly in oocytes disrupts chromosome alignmentEMBO reports2018
Okumura, Masako et al.Dynein–dynactin–NuMA clusters generate cortical spindle-pulling forces as a multiarm ensembleeLife2018
Elting, Mary Williard et al.Mapping Load-Bearing in the Mammalian Spindle Reveals Local Kinetochore Fiber Anchorage that Provides Mechanical Isolation and RedundancyCurrent Biology2017
Sampson, Josephina et al.Hsp72 and Nek6 cooperate to cluster amplified centrosomes in cancer cellsCancer Research2017
Long, Alexandra F. et al.Hec1 Tail Phosphorylation Differentially Regulates Mammalian Kinetochore Coupling to Polymerizing and Depolymerizing MicrotubulesCurrent Biology2017
Kollareddy, Madhu et al.The small molecule inhibitor YK-4-279 disrupts mitotic progression of neuroblastoma cells, overcomes drug resistance and synergizes with inhibitors of mitosisCancer Letters2017
Hsu, Hsiang Ting et al.Measurement of lytic granule convergence after formation of an NK cell immunological synapseMethods in Molecular Biology2017
Magliocca, Valentina et al.Identifying the dynamics of actin and tubulin polymerization in iPSCs and in iPSC-derived neuronsOncotarget2017
Stojkov, Darko et al.ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formationJournal of Cell Biology2017
Segal, Dagan et al.Adhesion and Fusion of Muscle Cells Are Promoted by FilopodiaDevelopmental Cell2016

CY-SC006: Cytoskeleton Kit (SiR-Actin and SiR-Tubulin)

AuthorTitleJournalYearArticle Link
Kalargyrou, Aikaterini A et al.Nanotube‐like processes facilitate material transfer between photoreceptorsEMBO reports2021
Crozet, Flora et al.Myosin-X is dispensable for spindle morphogenesis and positioning in the mouse oocyteDevelopment (Cambridge, England)2021
Adamczyk, Olga et al.Substrate Stiffness Mediates Formation of Novel Cytoskeletal Structures in Fibroblasts during Cell–Microspheres InteractionInternational Journal of Molecular Sciences 2021, Vol. 22, Page 9602021
Liu, Jiahao et al.Deep learning–enhanced fluorescence microscopy via degeneration decouplingOptics Express, Vol. 28, Issue 10, pp. 14859-148732020
Rafati, Yousef et al.Effect of microtubule resonant frequencies on neuronal cellshttps://doi.org/10.1117/12.25465692020
Hagemann, Philipp et al.Correlative Stimulated Emission Depletion and Scanning Ion Conductance MicroscopyACS Nano2018
Osborne, Suzanne E. et al.Type I interferon promotes cell-to-cell spread of Listeria monocytogenesCellular Microbiology2017

CY-SC014: SiR700-Tubulin Kit

AuthorTitleJournalYearArticle Link
Chang, Chih Chia et al.Regulatable assembly of synthetic microtubule architectures using engineered microtubule-associated protein-IDR condensatesJournal of Biological Chemistry2024
Tsuchiya, Kenta et al.Ran-GTP Is Non-essential to Activate NuMA for Mitotic Spindle-Pole Focusing but Dynamically Polarizes HURP Near ChromosomesCurrent Biology2021

CY-SC203: SPY555-tubulin

AuthorTitleJournalYearArticle Link
Jongsma, Marlieke L.M. et al.Systems mapping of bidirectional endosomal transport through the crowded cellCurrent Biology2024
Machado, Marta et al.Plasmodium falciparum CRK4 links early mitotic events to the onset of S-phase during schizogonymBio2023
So, Chun et al.Mechanism of spindle pole organization and instability in human oocytesScience2022
Dema, Alessandro et al.Optogenetic EB1 inactivation shortens metaphase spindles by disrupting cortical force-producing interactions with astral microtubulesCurrent Biology2022
Simon, Caroline S. et al.An extended DNA-free intranuclear compartment organizes centrosome microtubules in malaria parasitesLife Science Alliance2021

CY-SC503: SPY650-tubulin

AuthorTitleJournalYearArticle Link
De Pace, Raffaella et al.Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degenerationNature Neuroscience 2024 27:62024
Zhang, Zichao et al.Tight Junction Component Occludin Binds to FIP5 to Regulate Endosome Trafficking and Mitotic Spindle FunctionAdvanced Science2024
Jongsma, Marlieke L.M. et al.Systems mapping of bidirectional endosomal transport through the crowded cellCurrent Biology2024
Machado, Marta et al.Plasmodium falciparum CRK4 links early mitotic events to the onset of S-phase during schizogonymBio2023
Houthaeve, Gaëlle et al.Transient nuclear lamin A/C accretion aids in recovery from vapor nanobubble-induced permeabilisation of the plasma membraneCellular and Molecular Life Sciences2022

MAP Proteins

BM01: BimC Kinesin Motor Domain Protein

AuthorTitleJournalYearArticle Link
Rickert, Keith W. et al.Discovery and biochemical characterization of selective ATP competitive inhibitors of the human mitotic kinesin KSPArchives of Biochemistry and Biophysics2008
Funk, C. Joel et al.Development of high-throughput screens for discovery of kinesin adenosine triphosphatase modulatorsAnalytical Biochemistry2004
Wada, Yuuko et al.Evidence for a Novel Affinity Mechanism of Motor-assisted Transport Along MicrotubulesMolecular Biology of the Cell2000
Endow, Sharyn A. et al.Determinants of Kinesin Motor PolarityScience1998

CP01: CENP-E Kinesin Motor Domain Protein

AuthorTitleJournalYearArticle Link
Payton, Marc et al.Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancersNature Cancer2023
Labrière, Christophe et al.New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluationsBioorganic and Medicinal Chemistry2016
Funk, C. Joel et al.Development of high-throughput screens for discovery of kinesin adenosine triphosphatase modulatorsAnalytical Biochemistry2004
Wada, Yuuko et al.Evidence for a Novel Affinity Mechanism of Motor-assisted Transport Along MicrotubulesMolecular Biology of the Cell2000
Endow, Sharyn A. et al.Determinants of Kinesin Motor PolarityScience1998

CR01: Chromokinesin Kinesin Motor Domain Protein

AuthorTitleJournalYearArticle Link
Payton, Marc et al.Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancersNature Cancer2023
Labrière, Christophe et al.New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluationsBioorganic and Medicinal Chemistry2016
Funk, C. Joel et al.Development of high-throughput screens for discovery of kinesin adenosine triphosphatase modulatorsAnalytical Biochemistry2004
Wada, Yuuko et al.Evidence for a Novel Affinity Mechanism of Motor-assisted Transport Along MicrotubulesMolecular Biology of the Cell2000
Endow, Sharyn A. et al.Determinants of Kinesin Motor PolarityScience1998

EG02: Eg5 Homolog Kinesin Motor Domain Protein - A. fumigatis Recombinant

AuthorTitleJournalYearArticle Link
Funk, C. Joel et al.Development of high-throughput screens for discovery of kinesin adenosine triphosphatase modulatorsAnalytical Biochemistry2004
Wada, Yuuko et al.Evidence for a Novel Affinity Mechanism of Motor-assisted Transport Along MicrotubulesMolecular Biology of the Cell2000
Endow, Sharyn A. et al.Determinants of Kinesin Motor PolarityScience1998

EG01: Eg5 Kinesin Motor Domain Protein - Homo sapien Recombinant

AuthorTitleJournalYearArticle Link
Payton, Marc et al.Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancersNature Cancer2023
Saint-Dizier, François et al.Discovery of 2-(3-Benzamidopropanamido)thiazole-5-carboxylate Inhibitors of the Kinesin HSET (KIFC1) and the Development of Cellular Target Engagement ProbesJournal of Medicinal Chemistry2023
Fukai, Ryota et al.Design, synthesis, and evaluation of a novel prodrug, a S-trityl-L-cysteine derivative targeting kinesin spindle proteinEuropean Journal of Medicinal Chemistry2021
Labrière, Christophe et al.New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluationsBioorganic and Medicinal Chemistry2016
Carbajales, Carlos et al.Structure-based design of new KSP-Eg5 inhibitors assisted by a targeted multicomponent reactionChemBioChem2014
Funk, C. Joel et al.Development of high-throughput screens for discovery of kinesin adenosine triphosphatase modulatorsAnalytical Biochemistry2004
Wada, Yuuko et al.Evidence for a Novel Affinity Mechanism of Motor-assisted Transport Along MicrotubulesMolecular Biology of the Cell2000
Endow, Sharyn A. et al.Determinants of Kinesin Motor PolarityScience1998

KF01: KIF3C Kinesin Motor Domain Protein

AuthorTitleJournalYearArticle Link
Payton, Marc et al.Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancersNature Cancer2023
Wada, Yuuko et al.Evidence for a Novel Affinity Mechanism of Motor-assisted Transport Along MicrotubulesMolecular Biology of the Cell2000
Endow, Sharyn A. et al.Determinants of Kinesin Motor PolarityScience1998

KC01: KIFC3 Kinesin Motor Domain Protein

AuthorTitleJournalYearArticle Link
Payton, Marc et al.Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancersNature Cancer2023
Labrière, Christophe et al.New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluationsBioorganic and Medicinal Chemistry2016
Funk, C. Joel et al.Development of high-throughput screens for discovery of kinesin adenosine triphosphatase modulatorsAnalytical Biochemistry2004
Wada, Yuuko et al.Evidence for a Novel Affinity Mechanism of Motor-assisted Transport Along MicrotubulesMolecular Biology of the Cell2000
Endow, Sharyn A. et al.Determinants of Kinesin Motor PolarityScience1998

KR01: Kinesin Heavy Chain Motor Domain Protein

AuthorTitleJournalYearArticle Link
Minckley, Taylor F. et al.Zn2+ decoration of microtubules arrests axonal transport and displaces tau, doublecortin, and MAP2CJournal of Cell Biology2023
Perdomo, Doranda et al. TbKINX1B: a novel BILBO1 partner and an essential protein in bloodstream form Trypanosoma brucei Parasite2022
Lin, Jong Wei et al.Dexamethasone accelerates muscle regeneration by modulating kinesin-1-mediated focal adhesion signalsCell Death Discovery2021
Labrière, Christophe et al.New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluationsBioorganic and Medicinal Chemistry2016
Kadakkuzha, Beena M. et al.High-throughput screening for small molecule modulators of motor protein kinesinAssay and Drug Development Technologies2014
Abnous, Khalil et al.Synthesis and molecular modeling of six novel monastrol analogues: Evaluation of cytotoxicity and kinesin inhibitory activity against HeLa cell lineDARU, Journal of Pharmaceutical Sciences2013
Soppina, Virupakshi et al.Luminal Localization of α-tubulin K40 Acetylation by Cryo-EM Analysis of Fab-Labeled MicrotubulesPLoS ONE2012
Gutiérrez-Medina, Braulio et al.Visualizing individual microtubules by bright field microscopyAmerican Journal of Physics2010
Del Duca, Stefano et al.Effects of post-translational modifications catalysed by pollen transglutaminase on the functional properties of microtubulesand actin filamentsBiochemical Journal2009
Funk, C. Joel et al.Development of high-throughput screens for discovery of kinesin adenosine triphosphatase modulatorsAnalytical Biochemistry2004
Wada, Yuuko et al.Evidence for a Novel Affinity Mechanism of Motor-assisted Transport Along MicrotubulesMolecular Biology of the Cell2000
Endow, Sharyn A. et al.Determinants of Kinesin Motor PolarityScience1998

MK01: MCAK Kinesin Motor Domain Protein

AuthorTitleJournalYearArticle Link
Payton, Marc et al.Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancersNature Cancer2023
Arellano-Santoyo, Hugo et al.A Tubulin Binding Switch Underlies Kip3/Kinesin-8 Depolymerase ActivityDevelopmental Cell2017
Rickert, Keith W. et al.Discovery and biochemical characterization of selective ATP competitive inhibitors of the human mitotic kinesin KSPArchives of Biochemistry and Biophysics2008
Funk, C. Joel et al.Development of high-throughput screens for discovery of kinesin adenosine triphosphatase modulatorsAnalytical Biochemistry2004
Wada, Yuuko et al.Evidence for a Novel Affinity Mechanism of Motor-assisted Transport Along MicrotubulesMolecular Biology of the Cell2000
Endow, Sharyn A. et al.Determinants of Kinesin Motor PolarityScience1998

MAPF: Microtubule Associated Portein Rich Fraction

AuthorTitleJournalYearArticle Link
Ait-Bouziad, Nadine et al.Phosphorylation of the overlooked tyrosine 310 regulates the structure, aggregation, and microtubule- And lipid-binding properties of TauJournal of Biological Chemistry2020
Liang, Hong et al.The microtubule-associated protein IQ67 DOMAIN5 modulates microtubule dynamics and pavement cell shapePlant Physiology2018
Gumy, Laura F. et al.MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus KIF5-Dependent Cargo Transport in Sensory NeuronsNeuron2017
Zhang, Xiang et al.Palladin is a novel microtubule-associated protein responsible for spindle orientationScientific Reports2017
Kesten, Christopher et al.In vitro Microtubule Binding Assay and Dissociation Constant EstimationBio-Protocol2016
Endler, Anne et al.A Mechanism for Sustained Cellulose Synthesis during Salt StressCell2015
He, Ze et al.Cytoplasmic retention of a nucleocytoplasmic protein TBC1D3 by microtubule network is required for enhanced EGFR signalingPLoS ONE2014
Wu, Jianchun et al.Caspase-mediated cleavage of C53/LZAP protein causes abnormal microtubule bundling and rupture of the nuclear envelopeCell Research2013
De La Mora-Rey, Teresa et al.The structure of the TOG-like domain of Drosophila melanogaster Mast/OrbitActa Crystallographica Section F: Structural Biology and Crystallization Communications2013
Zhu, Mei et al.MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progressionJournal of Cell Biology2013
Tu-Sekine, Becky et al.Dual regulation of diacylglycerol kinase (DGK)-θ: Polybasic proteins promote activation by phospholipids and increase substrate affinityJournal of Biological Chemistry2012
Mei, Yu et al.The Arabidopsis ARCP protein, CSI1, which is required for microtubule stability, is necessary for root and anther developmentPlant Cell2012
Azakir, Bilal A. et al.Dysferlin interacts with tubulin and microtubules in mouse skeletal musclePLoS ONE2010
Sackett, Dan L. et al.Intracellular proadrenomedullin-derived peptides decorate the microtubules and contribute to cytoskeleton functionEndocrinology2008
Smith, Jason G. et al.Neutralizing Antibody Blocks Adenovirus Infection by Arresting Microtubule-Dependent Cytoplasmic TransportJournal of Virology2008
Farooqui, Akhlaq A. et al.Inhibitors of brain phospholipase A2 activity: Their neuropharmacological effects and therapeutic importance for the treatment of neurologic disordersPharmacological Reviews2006
Teckchandani, Anjali M. et al.The multidomain protooncogenic protein c-Cbl binds to tubulin and stabilizes microtubulesExperimental cell research2005
Cho, Hyekyung P. et al.The dual-specificity phosphatase CDC14B bundles and stabilizes microtubulesMolecular and cellular biology2005
Satish, Latha et al.Interferon-Inducible Protein 9 (CXCL11)-Induced Cell Motility in Keratinocytes Requires Calcium Flux-Dependent Activation of μ-CalpainMolecular and Cellular Biology2005
Mamoune, Asmaa et al.DU145 human prostate carcinoma invasiveness is modulated by urokinase receptor (uPAR) downstream of epidermal growth factor receptor (EGFR) signaling.Experimental cell research2004
Sato, Hiromi et al.The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoUEMBO Journal2003
Nielsen, Finn C. et al.Cytoplasmic trafficking of IGF-II mRNA-binding protein by conserved KH domainsJournal of Cell Science2002

MP01: MKLP Kinesin Motor Domain Protein

AuthorTitleJournalYearArticle Link
Payton, Marc et al.Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancersNature Cancer2023
Funk, C. Joel et al.Development of high-throughput screens for discovery of kinesin adenosine triphosphatase modulatorsAnalytical Biochemistry2004
Wada, Yuuko et al.Evidence for a Novel Affinity Mechanism of Motor-assisted Transport Along MicrotubulesMolecular Biology of the Cell2000
Endow, Sharyn A. et al.Determinants of Kinesin Motor PolarityScience1998

TA01: Tau Protein

AuthorTitleJournalYearArticle Link
Selvarasu, Karthikeyan et al.Interaction of Tau with Kinesin-1: Effect of Kinesin-1 Heavy Chain Elimination on Autophagy-Mediated Mutant Tau DegradationBiomedicines2024
Henty-Ridilla, Jessica L.Visualizing Actin and Microtubule Coupling Dynamics In Vitro by Total Internal Reflection Fluorescence (TIRF) MicroscopyJoVE (Journal of Visualized Experiments)2022
Feizabadi, Mitra Shojania et al.The Effect of Tau and Taxol on Polymerization of MCF7 Microtubules In VitroInternational Journal of Molecular Sciences2022
Neal, C. L. et al.Microtubule-associated protein tau: A marker of pac******* sensitivity in breast cancerBreast Diseases2006
Roger, Benoit et al.MAP2c, but not tau, binds and bundles F-actin via its microtubule binding domain2004

Microtubules

MT002: Tubulin Protein (Pre-formed Microtubules) - Porcine Brain

AuthorTitleJournalYearArticle Link
Schutt, Katherine L. et al.Identification of the KIF18A alpha-4 helix as a therapeutic target for chromosomally unstable tumor cellsFrontiers in Molecular Biosciences2024
Babcock, N. S. et al.Ultraviolet Superradiance from Mega-Networks of Tryptophan in Biological ArchitecturesJournal of Physical Chemistry B2024
Kalashova, Julia et al.The Aurora kinase B relocation blocker LXY18 triggers mitotic catastrophe selectively in malignant cellsPLOS ONE2023
Saint-Dizier, François et al.Discovery of 2-(3-Benzamidopropanamido)thiazole-5-carboxylate Inhibitors of the Kinesin HSET (KIFC1) and the Development of Cellular Target Engagement ProbesJournal of Medicinal Chemistry2023
Perdomo, Doranda et al. TbKINX1B: a novel BILBO1 partner and an essential protein in bloodstream form Trypanosoma brucei Parasite2022
Zhang, Wenxu et al.Fano resonance line shapes in the Raman spectra of tubulin and microtubules reveal quantum effectsBiophysical Reports2022
Sharma, A. et al.Structural stability of SARS-CoV-2 virus like particles degrades with temperatureBiochemical and Biophysical Research Communications2021
Mok, Jung Wan et al.Novel function of N-acetyltransferase for microtubule stability and JNK signaling in Drosophila organ developmentProceedings of the National Academy of Sciences of the United States of America2021
Sandberg, Alexander et al.Fibrillation and molecular characteristics are coherent with clinical and pathological features of 4-repeat tauopathy caused by MAPT variant G273RNeurobiology of Disease2020
Chiolerio, Alessandro et al.On resistance switching and oscillations in tubulin microtubule dropletsJournal of Colloid and Interface Science2020
von Appen, Alexander et al.LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformationNature2020
Patterson, Jesse C. et al.VISAGE Reveals a Targetable Mitotic Spindle Vulnerability in Cancer CellsCell Systems2019
Labrière, Christophe et al.New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluationsBioorganic and Medicinal Chemistry2016
Sato, T. et al.JSAP1/JIP3 and JLP regulate kinesin-1-dependent axonal transport to prevent neuronal degenerationCell Death and Differentiation2015
Hanson, Susan M. et al.Arrestin Mobilizes Signaling Proteins to the Cytoskeleton and Redirects their ActivityJournal of Molecular Biology2007

Tubulin Proteins

T240: Tubulin Protein (>99% Pure) Lyophilized - Porcine Brain

AuthorTitleJournalYearArticle Link
Zhou, Qing et al.An orphan kinesin in Trypanosoma brucei regulates hook complex assembly and Golgi biogenesismBio2024
Babcock, N. S. et al.Ultraviolet Superradiance from Mega-Networks of Tryptophan in Biological ArchitecturesJournal of Physical Chemistry B2024
Benoit, Matthieu P.M.H. et al.Cryo-EM unveils kinesin KIF1A’s processivity mechanism and the impact of its pathogenic variant P305LNature Communications2024
Ballmer, Daniel et al.Dynamic localization of the chromosomal passenger complex in trypanosomes is controlled by the orphan kinesins KIN-A and KIN-BeLife2024
Lucero, Bobby et al.Design, Synthesis, and Evaluation of An Anti-trypanosomal [1,2,4]Triazolo[1,5-a]pyrimidine Probe for Photoaffinity Labeling StudiesChemMedChem2024
Singh, Sudhir K. et al.Noncanonical interaction with microtubules via the N-terminal nonmotor domain is critical for the functions of a bidirectional kinesinScience Advances2024
Heber, Simone et al.Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transportNature Structural & Molecular Biology 2024
Ceglowski, Julia et al.TTLL12 is required for primary ciliary axoneme formation in polarized epithelial cellsEMBO Reports2024
Fan, Yuanwei et al.A divergent tumor overexpressed gene domain and oligomerization contribute to SPIRAL2 function in stabilizing microtubule minus endsThe Plant Cell2024
Adler, Agnes et al.A structural and dynamic visualization of the interaction between MAP7 and microtubulesNature Communications2024
Liu, Xinglei et al.Kinesin-14 HSET and KlpA are non-processive microtubule motors with load-dependent power strokesNature Communications2024
Mahalingan, Kishore K. et al.Structural basis for α-tubulin-specific and modification state-dependent glutamylationNature Chemical Biology2024
Rai, Dipti et al.CAMSAPs and nucleation-promoting factors control microtubule release from γ-TuRCNature Cell Biology2024
Chauhan, Prashali et al.Ionic strength alters crosslinker-driven self-organization of microtubulesCytoskeleton2024
Yeh, Hung Wei et al.Cep57 regulates human centrosomes through multivalent interactionsProceedings of the National Academy of Sciences2024
Seo, Dahee et al.Poxvirus A51R proteins regulate microtubule stability and antagonize a cell-intrinsic antiviral responseCell Reports2024
Liang, Xiaolin et al.LncRNA TubAR complexes with TUBB4A and TUBA1A to promote microtubule assembly and maintain myelinationCell Discovery2024
Hu, Huiqing et al.A kinesin-13 family kinesin in Trypanosoma brucei regulates cytokinesis and cytoskeleton morphogenesis by promoting microtubule bundlingPLOS Pathogens2024
Tezuka, Toshiki et al.Clinical characteristics and pathophysiological properties of newly discovered LRRK2 variants associated with Parkinson's diseaseNeurobiology of Disease2024
Di Gregorio, Elisabetta et al.Raman Spectroscopy Reveals Photobiomodulation-Induced α-Helix to β-Sheet Transition in Tubulins: Potential Implications for Alzheimer’s and Other Neurodegenerative DiseasesNanomaterials2024
Fan, Weijing et al.A novel conductive microtubule hydrogel for electrical stimulation of chronic wounds based on biological electrical wiresJournal of Nanobiotechnology2024
Patrón, Lilian A. et al.Novel Brain-Penetrant, Small-Molecule Tubulin Destabilizers for the Treatment of GlioblastomaBiomedicines2024
Ranaivoson, Fanomezana Moutse et al.Nucleotide-free structures of KIF20A illuminate atypical mechanochemistry in this kinesin-6Open Biology2023
Gritsina, Galina et al.Chemokine receptor CXCR7 activates Aurora Kinase A and promotes neuroendocrine prostate cancer growthThe Journal of Clinical Investigation2023
Memarian, Fereshteh L. et al.Forming, Confining, and Observing Microtubule-Based Active NematicsJournal of Visualized Experiments (JoVE)2023
van den Berg, Cyntha M. et al.CSPP1 stabilizes growing microtubule ends and damaged lattices from the luminal sideJournal of Cell Biology2023
Wang, Yujuan et al.CCP5 and CCP6 retain CP110 and negatively regulate ciliogenesisBMC Biology2023
Bahri, Salima et al.1H-detected characterization of carbon–carbon networks in highly flexible protonated biomolecules using MAS NMRJournal of Biomolecular NMR2023
Minckley, Taylor F. et al.Zn2+ decoration of microtubules arrests axonal transport and displaces tau, doublecortin, and MAP2CJournal of Cell Biology2023
McGorty, Ryan J. et al.Kinesin and myosin motors compete to drive rich multiphase dynamics in programmable cytoskeletal compositesPNAS Nexus2023
Nithianantham, Stanley et al.The kinesin-5 tail and bipolar minifilament domains are the origin of its microtubule crosslinking and sliding activityMolecular biology of the cell2023
Hsieh, Yao Yu et al.Repositioning VU-0365114 as a novel microtubule-destabilizing agent for treating cancer and overcoming drug resistanceMolecular Oncology2023
Hoshino, Asumi et al.The microtubule-severing protein UNC-45A preferentially binds to curved microtubules and counteracts the microtubule-straightening effects of TaxolJournal of Biological Chemistry2023
Kalra, Aarat P. et al.Electronic Energy Migration in MicrotubulesACS Central Science2023
Hagita-Tatsumoto, Ayaka et al.Quantitative Microtubule Fractionation Technique to Separate Stable Microtubules, Labile Microtubules, and Free Tubulin in Mouse TissuesJoVE (Journal of Visualized Experiments)2023
McMillan, Pamela J. et al.Tau–RNA complexes inhibit microtubule polymerization and drive disease-relevant conformation changeBrain2023
Morishita, Jun et al.Identification of a small RhoA GTPase inhibitor effective in fission yeast and human cellsOpen Biology2023
Sharma, Sachin et al.Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancerJournal of Enzyme Inhibition and Medicinal Chemistry2023
Palumbo, Jacob et al.Directly Measuring Forces Within Reconstituted Active Microtubule BundlesJoVE (Journal of Visualized Experiments)2022
Henty-Ridilla, Jessica L.Visualizing Actin and Microtubule Coupling Dynamics In Vitro by Total Internal Reflection Fluorescence (TIRF) MicroscopyJoVE (Journal of Visualized Experiments)2022
Sasanpour, Mehrzad et al.Reconstituting and Characterizing Actin-Microtubule Composites with Tunable Motor-Driven Dynamics and MechanicsJoVE (Journal of Visualized Experiments)2022
Planelles-Herrero, Vicente Jose et al.Elongator stabilizes microtubules to control central spindle asymmetry and polarized trafficking of cell fate determinantsNature Cell Biology 2022
Feizabadi, Mitra Shojania et al.The Effect of Tau and Taxol on Polymerization of MCF7 Microtubules In VitroInternational Journal of Molecular Sciences2022
Yang, Yun et al.Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer’s diseaseNature Communications2022
Kuzmić, Mira et al.Septin-microtubule association via a motif unique to isoform 1 of septin 9 tunes stress fibersJournal of Cell Science2022
Capizzi, Mariacristina et al.Developmental defects in Huntington's disease show that axonal growth and microtubule reorganization require NUMA1Neuron2022
Lee, Gloria et al.Myosin-driven actin-microtubule networks exhibit self-organized contractile dynamicsScience Advances2021
Hough, Cameron M. et al.Disassembly of microtubules by intense terahertz pulsesBiomedical Optics Express2021
Watson, Joseph L. et al.High-efficacy subcellular micropatterning of proteins using fibrinogen anchorsJournal of Cell Biology2021
Elahi, Montasir et al.High-fat diet–induced activation of SGK1 promotes Alzheimer’s disease–associated tau pathologyHuman Molecular Genetics2021
Zhou, Libin et al.Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegenerationScientific Reports 2021
Budaitis, Breane G. et al.Pathogenic mutations in the kinesin-3 motor KIF1A diminish force generation and movement through allosteric mechanismsJournal of Cell Biology2021
Habicht, Juri et al.UNC-45A breaks the microtubule lattice independently of its effects on non-muscle myosin IIJournal of Cell Science2021
Gao, Li et al.A Robust, GFP-Orthogonal Photoswitchable Inhibitor Scaffold Extends Optical Control over the Microtubule CytoskeletonCell Chemical Biology2021
Nakayama, Shogo et al.Planar cell polarity induces local microtubule bundling for coordinated ciliary beatingJournal of Cell Biology2021
Ludzia, Patryk et al.Structural characterization of KKT4, an unconventional microtubule-binding kinetochore proteinStructure2021
Kundu, Tanushree et al.Coupling of dynamic microtubules to F-actin by Fmn2 regulates chemotaxis of neuronal growth conesJournal of Cell Science2021
Kaur, Simranpreet et al.Expansion of the phenotypic spectrum of de novo missense variants in kinesin family member 1A (KIF1A)Human Mutation2020
Baker, Stacey J. et al.A Contaminant Impurity, Not Rigosertib, Is a Tubulin Binding AgentMolecular Cell2020
Ricketts, Shea N. et al.Triggering Cation-Induced Contraction of Cytoskeleton Networks via MicrofluidicsFrontiers in Physics2020
Diwaker, Drishya et al.Deletion of the Pseudorabies virus gE/gI-US9p complex disrupts kinesin KIF1A and KIF5C recruitment during egress, and alters the properties of microtubule-dependent transport in vitroPLoS Pathogens2020
Ouyang, Changhan et al.Autophagic degradation of KAT2A/GCN5 promotes directional migration of vascular smooth muscle cells by reducing TUBA/α-tubulin acetylationAutophagy2020
Müller-Deku, Adrian et al.Photoswitchable pac*******-based microtubule stabilisers allow optical control over the microtubule cytoskeletonNature Communications2020
Alatrash, Nagham et al.Disruption of microtubule function in cultured human cells by a cytotoxic ruthenium(ii) polypyridyl complexChemical Science2020
Kraus, Yvonne et al.Isoquinoline-based biaryls as a robust scaffold for microtubule inhibitorsEuropean Journal of Medicinal Chemistry2020
Aher, Amol et al.CLASP Mediates Microtubule Repair by Restricting Lattice Damage and Regulating Tubulin IncorporationCurrent Biology2020
Gunji, Shizuka et al.Excess Pyrophosphate Restrains Pavement Cell Morphogenesis and Alters Organ Flatness in Arabidopsis thalianaFrontiers in Plant Science2020
Francis, Madison L. et al.Non-monotonic dependence of stiffness on actin crosslinking in cytoskeleton compositesSoft Matter2019
Leong, Su Ling et al.Reconstitution of Microtubule Nucleation In Vitro Reveals Novel Roles for Mzt1Current Biology2019
Lopes, Joseph et al.Membrane mediated motor kinetics in microtubule gliding assaysScientific Reports2019
Nakos, Konstantinos et al.Regulation of microtubule plus end dynamics by septin 9Cytoskeleton2019
Ng, Cai Tong et al.Electron cryotomography analysis of Dam1C/DASH at the kinetochore-spindle interface in situJournal of Cell Biology2019
Guzman-Sepulveda, Jose Rafael et al.Tubulin Polarizability in Aqueous SuspensionsACS Omega2019
Karasmanis, Eva P. et al.Erratum: Polarity of Neuronal Membrane Traffic Requires Sorting of Kinesin Motor Cargo during Entry into Dendrites by a Microtubule-Associated Septin (Developmental Cell (2018) 46(2) (204–218.e7), (S1534580718304982) (10.1016/j.devcel.2018.06.013))Developmental Cell2018
Ganguly, Anindya et al.Importin-β Directly Regulates the Motor Activity and Turnover of a Kinesin-4Developmental Cell2018
Fan, Yuanwei et al.The Arabidopsis SPIRAL2 Protein Targets and Stabilizes Microtubule Minus EndsCurrent Biology2018
Romé, Pierre et al.A novel microtubule nucleation pathway for meiotic spindle assembly in oocytesJournal of Cell Biology2018
Tripathy, Ratna et al.Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical MalformationsNeuron2018
Murray, John W. et al.Reduction of organelle motility by removal of potassium and other solutesPLoS ONE2017
Kandel, Mikhail E. et al.Label-Free Imaging of Single Microtubule Dynamics Using Spatial Light Interference MicroscopyACS Nano2017
Okeyoshi, Kosuke et al.Methods for the self-integration of megamolecular biopolymers on the drying air-LC interfaceJournal of Visualized Experiments2017
Majellaro, Maria et al.Investigating Structural Requirements for the Antiproliferative Activity of Biphenyl NicotinamidesChemMedChem2017
Onder, Seda et al.Monoclonal Antibody That Recognizes Diethoxyphosphotyrosine-Modified Proteins and Peptides Independent of Surrounding Amino AcidsChemical Research in Toxicology2017
Monda, Julie K. et al.Microtubule Tip Tracking by the Spindle and Kinetochore Protein Ska1 Requires Diverse Tubulin-Interacting SurfacesCurrent Biology2017
Howes, Stuart C. et al.Structural differences between yeast and mammalian microtubules revealed by cryo-EMJournal of Cell Biology2017
Ghaly, Peter E. et al.A new antiproliferative noscapine analogue: Chemical synthesis and biological evaluationOncotarget2016
Lor, Chai et al.A simple experimental model to investigate force range for membrane nanotube formationFrontiers in Materials2016
Ayoub, Ahmed Taha et al.Antitumor Activity of Lankacidin Group Antibiotics Is Due to Microtubule Stabilization via a Pac*******-like MechanismJournal of Medicinal Chemistry2016
Matsuyama, Tomonori et al.Midaz(olam) inhibits the hypoxia-induced up-regulation of erythropoietin in the central nervous systemEuropean Journal of Pharmacology2015
Hara, Yuki et al.Dynein-Based Accumulation of Membranes Regulates Nuclear Expansion in Xenopus laevis Egg ExtractsDevelopmental Cell2015
Kim, Kyongwan et al.Electric field-induced reversible trapping of microtubules along metallic glass microwire electrodesJournal of Applied Physics2015
Taberner, Núria et al.Reconstituting Functional Microtubule-Barrier InteractionsMethods in Cell Biology2014
Hosono, Hitomi et al.The murine Gcap14 gene encodes a novel microtubule binding and bundling proteinFEBS letters2012
Kawakami, Fumitaka et al.LRRK2 phosphorylates tubulin-associated tau but not the free molecule: LRRK2-mediated regulation of the tau-tubulin association and neurite outgrowthPloS one2012
Berezniuk, Iryna et al.Cytosolic Carboxypeptidase 1 Is Involved in Processing α- and β-TubulinThe Journal of Biological Chemistry2012
Wu, Hui Yuan et al.A structural and functional analysis of Nna1 in Purkinje cell degeneration (pcd) miceThe FASEB Journal2012
Wells, David B. et al.Mechanical properties of a complete microtubule revealed through molecular dynamics simulationBiophysical Journal2010
Iuchi, Katsuya et al.heterocyclic organobismuth(III) compound targets tubulin to induce G 2/M arrest in hela cellsJournal of Pharmacological Sciences2009
Ligon, Lee A. et al.The Microtubule Plus-End Proteins EB1 and Dynactin Have Differential Effects on Microtubule PolymerizationMolecular Biology of the Cell2003
Faivre-Moskalenko, Cendrine et al.Dynamics of microtubule asters in microfabricated chambers: The role of catastrophesProceedings of the National Academy of Sciences of the United States of America2002

T238P: Tubulin Protein (>99% Pure) Frozen - Porcine Brain

AuthorTitleJournalYearArticle Link
Robinson, Benjamin P. et al.Septin-coated microtubules promote maturation of multivesicular bodies by inhibiting their motilityJournal of Cell Biology2024
Mahalingan, Kishore K. et al.Structural basis for α-tubulin-specific and modification state-dependent glutamylationNature Chemical Biology2024
Chen, Jiayi et al.Tubulin code eraser CCP5 binds branch glutamates by substrate deformationNature2024
Yang, Shuzhen et al.EB1 decoration of microtubule lattice facilitates spindle-kinetochore lateral attachment in Plasmodium male gametogenesisNature Communications2023
Qian, Pengge et al.Apical anchorage and stabilization of subpellicular microtubules by apical polar ring ensures Plasmodium ookinete infection in mosquitoNature Communications 2022
Yim, Junhyeong et al.Phenotype-based screening rediscovered benzopyran-embedded microtubule inhibitors as anti-neuroinflammatory agents by modulating the tubulin–p65 interactionExperimental & Molecular Medicine 2022
Chen, Jiayi et al.Α-Tubulin Tail Modifications Regulate Microtubule Stability Through Selective Effector Recruitment, Not Changes in Intrinsic Polymer DynamicsDevelopmental Cell2021
Karki, Menuka et al.A cytoskeletal function for PBRM1 reading methylated microtubulesScience Advances2021
Qiu, Rongde et al.Dynein activation in vivo is regulated by the nucleotide states of its AAA3 domainCurrent Biology2021
Zehr, Elena A. et al.Katanin Grips the β-Tubulin Tail through an Electropositive Double Spiral to Sever MicrotubulesDevelopmental Cell2020
Gudimchuk, Nikita B. et al.Mechanisms of microtubule dynamics and force generation examined with computational modeling and electron cryotomographyNature Communications2020
von Appen, Alexander et al.LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformationNature2020
Fees, Colby P. et al.A unified model for microtubule rescueMolecular Biology of the Cell2019
Richard McIntosh, J. et al.Microtubules grow by the addition of bent guanosine triphosphate tubulin to the tips of curved protofilamentsJournal of Cell Biology2018
Zhang, Kai et al.Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and ActivatedCell2017
Miyake, Yasuyuki et al.Structural insights into HDAC6 tubulin deacetylation and its selective inhibitionNature Chemical Biology2016
Yang, Jianhong et al.Pironetin reacts covalently with cysteine-316 of α-tubulin to destabilize microtubuleNature Communications2016
Yi, Jun Mei et al.Dual targeting of microtubule and topoisomerase II by α-carboline derivative YCH337 for tumor proliferation and growth inhibitionOncotarget2015
Yan, Jun et al.A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cellsBiochemical Pharmacology2015
Szyk, Agnieszka et al.Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferaseCell2014
Volkov, Vladimir A. et al.Preparation of segmented microtubules to study motions driven by the disassembling microtubule endsJournal of Visualized Experiments2014
King, S. J. et al.Dynactin increases the processivity of the cytoplasmic dynein motorNature cell biology2000
Gradin, Helena Melander et al.Regulation of Microtubule Dynamics by Extracellular Signals: cAMP-dependent Protein Kinase Switches Off the Activity of Oncoprotein 18 in Intact CellsThe Journal of Cell Biology1998
Lee Virginia, M. Y. et al.Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17Science (New York, N.Y.)1998
Sosa, Hernando et al.A Model for the Microtubule-Ncd Motor Protein Complex Obtained by Cryo-Electron Microscopy and Image AnalysisCell1997

HTS03: Tubulin Protein (97% Pure) - Porcine Brain

AuthorTitleJournalYearArticle Link
Zhang, Guohui et al.Metabolic profiling identifies Qrich2 as a novel glutamine sensor that regulates microtubule glutamylation and mitochondrial function in mouse spermCellular and Molecular Life Sciences2024
Tsuji, Chisato et al.CryoET reveals actin filaments within platelet microtubulesNature Communications2024
Hino, Mizuki et al.Tubulin/microtubules as novel clozapine targetsNeuropsychopharmacology Reports2022
Tjioe, Marco et al.Multiple kinesins induce tension for smooth cargo transporteLife2019
Chen, Yang et al.Visualizing Autophagic Lysosome Reformation in Cells Using In Vitro Reconstitution SystemsCurrent Protocols in Cell Biology2018
Qi, Jianguo et al.Synthesis and biological evaluation of N-substituted 3-oxo-1,2,3,4-tetrahydro-quinoxaline-6-carboxylic acid derivatives as tubulin polymerization inhibitorsEuropean Journal of Medicinal Chemistry2018
Khatra, Harleen et al.Hedgehog Antagonist Pyrimidine–Indole Hybrid Molecule Inhibits Ciliogenesis through Microtubule DestabilisationChemBioChem2018
Su, Qian Peter et al.Corrigendum: Vesicle Size Regulates Nanotube Formation in the CellScientific reports2017
Zhang, Rui et al.Interplay of structure, elasticity, and dynamics in actin-based nematic materialsProceedings of the National Academy of Sciences of the United States of America2017
Francis, Joshua W. et al.A trimer consisting of the Tubulin-specific Chaperone D (TBCD), regulatory GTPase ARL2, and β-tubulin is required for maintaining the microtubule networkJournal of Biological Chemistry2017
Du, Wanqing et al.Kinesin 1 Drives Autolysosome TubulationDevelopmental Cell2016
Magalhaes, Luma G. et al.Discovery of a series of acridinones as mechanism-based tubulin assembly inhibitors with anticancer activityPLoS ONE2016
Wang, Chong et al.Dynamic tubulation of mitochondria drives mitochondrial network formationCell Research2015
Talà, Adelfia et al.Serogroup-specific interaction of Neisseria meningitidis capsular polysaccharide with host cell microtubules and effects on tubulin polymerizationInfection and Immunity2014
Li, Chien Ming et al.Orally Bioavailable Tubulin Antagonists for Pac*******-Refractory CancerPharmaceutical Research 2012 29:112012
Samson, Andre L. et al.Nucleocytoplasmic Coagulation: An Injury-Induced Aggregation Event that Disulfide Crosslinks Proteins and Facilitates Their Removal by PlasminCell Reports2012
Sackett, Dan L. et al.Intracellular proadrenomedullin-derived peptides decorate the microtubules and contribute to cytoskeleton functionEndocrinology2008

H003: Tubulin Protein (Biotin Labeled) - Hela Cancer Cell

F001: Tubulin Protein - A. bisporus

ML116: Tubulin Protein - MAP Rich - Porcine Brain

AuthorTitleJournalYearArticle Link
Li, Xiaofan et al.Discovery of STRO-002, a Novel Homogeneous ADC Targeting Folate Receptor Alpha, for the Treatment of Ovarian and Endometrial CancersMolecular Cancer Therapeutics2023
Chang, Chi I. et al.Synthesis and Structure–Activity Relationship of Salvinal Derivatives as Potent Microtubule InhibitorsInternational Journal of Molecular Sciences2023
Muñoz-Torrero, Diego et al.Chlorpyrifos Oxon Activates Glutamate and Lysine for Protein Cross-linkingChemical Research in Toxicology2023
Schopfer, Lawrence M. et al.Organophosphorus Pesticides Promote Protein Cross-LinkingChemical Research in Toxicology2022
Schopfer, Lawrence M. et al.Evaluation of mass spectrometry MS/MS spectra for the presence of isopeptide crosslinked peptidesPLoS ONE2021
Baker, Stacey J. et al.A Contaminant Impurity, Not Rigosertib, Is a Tubulin Binding AgentMolecular Cell2020
You, Zhiyuan et al.Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stressNature Communications2019
Tripathy, Ratna et al.Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical MalformationsNeuron2018
Rath, S. et al.Anti-angiogenic effects of the tubulysin precursor pretubulysin and of simplified pretubulysin derivativesBritish journal of pharmacology2012
Hsieh, Cheng Chih et al.Chamaecypanone C, a novel skeleton microtubule inhibitor, with anticancer activity by trigger caspase 8-Fas/FasL dependent apoptotic pathway in human cancer cellsBiochemical Pharmacology2010

CS-TAC01: Acetylated Tubulin Protein - Porcine Brain

Tubulin Info
Tubulin Info Resources
Technical Support