Cytoskeleton, Inc. has been a trusted provider of recombinant and native protein production services for 30+ years. What sets us apart is our focus on consistent quality—we deliver uniform protein batches to support your project from discovery to scale-up. Consistency isn’t just our goal, it’s our guarantee.
We support diagnostic development, HTS workflows, and exploratory discovery with custom protein production services. Beyond monomeric recombinant proteins, clients rely on Cyto for complex purifications like specialized tubulins, multiprotein complexes (e.g., actin thin filaments, Arp2/3), and native proteins (e.g., myosins, dynein). Each project includes validated activity assays to ensure bio-functionality—an essential component of our end-to-end workflow.
Cytoskeleton partners closely with your team to deliver custom protein production according to your specifications, leveraging deep expertise in cytoskeletal biology and protein biochemistry. Our high-quality service supports key project decisions, while our focus on collaboration and reliability keeps leading pharma and biotech companies returning year after year.
Parameter | Cyto expertise available | Inquire |
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Protein type |
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Recombinant expression system |
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Construct design |
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Amount required |
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Purity required |
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Biological activity determination |
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Target protein modification |
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A Fortune 500 biopharmaceutical company required a reproducible, high-purity source of actin thin filaments along with the corresponding skeletal muscle myosin subfragment-1 (S1) to develop and validate a calcium-regulated myosin ATPase assay. This assay was designed to accurately reflect the calcium sensitivity of actomyosin interactions in a controlled, in vitro setting.
Our team strategically structured the work into five clear phases, delivering results at each stage over a period of seven months. We successfully isolated and validated six native proteins with confirmed biological activity, and co-developed robust, validated assays with the client. Deliverables included user-friendly lyophilized proteins and a reliable, easy-to-interpret assay system. Our custom proteins enabled the client to generate hits and refine lead compounds targeting cardiomyopathies.
We proudly support leading research teams across pharma, biotech, and academia. Our custom services have helped advance discovery and preclinical programs in oncology, neuroscience, cardiology, and beyond.