Small G-protein GEF/GAP & ELISA kits
Three classes of proteins tightly regulate small G-proteins: Guanine Nucleotide Exchange Factors (GEFs), GTPase-Activating Proteins (GAPs), and Guanine Nucleotide Dissociation Inhibitors (GDIs).
- GEFs activate small GTPases by facilitating the exchange of GDP for GTP.
- GAPs inactivate GTPases by accelerating the hydrolysis of GTP to GDP
- GDIs maintain GTPases in their inactive GDP-bound state by preventing GDP dissociation.
Cyto offers a range of in vitro assay kits for quantitatively measuring GEF and GAP activity. The kits are ideal for biochemical characterization and high-throughput drug discovery screening. Additionally, we offer a RhoA ELISA assay for the specific detection and quantification of total RhoA.
Three classes of proteins tightly regulate small G-proteins: Guanine Nucleotide Exchange Factors (GEFs), GTPase-Activating Proteins (GAPs), and Guanine Nucleotide Dissociation Inhibitors (GDIs).
- GEFs activate small GTPases by facilitating the exchange of GDP for GTP.
- GAPs inactivate GTPases by accelerating the hydrolysis of GTP to GDP
- GDIs maintain GTPases in their inactive GDP-bound state by preventing GDP dissociation.
Cyto offers a range of in vitro assay kits for quantitatively measuring GEF and GAP activity. The kits are ideal for biochemical characterization and high-throughput drug discovery screening. Additionally, we offer a RhoA ELISA assay for the specific detection and quantification of total RhoA.
