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Small G-protein products

Since 1994, Cyto has been at the forefront of small G-protein research.

In consultation with Dr. Alan Hall—a pioneer in the field—we launched the first line of small GTPase reagents. With over 4,000 citations and decades of innovation, we are proud to have contributed to the advancement of small G-protein research.

Today, we continue to support scientists with quality, innovative tools, and expert technical support.

Small G-protein Activators & Inhibitors

Cell-permeable reagents to study Rac, Rho, or Cdc42 functions in live cells.

Small G-protein Activation Assays

Easy-to-use pull-down or G-LISA® kits to detect active GTP-bound small GTPases.

Small GTPase Affinity Beads

Discover versatile affinity beads to capture active GTP-bound small G-proteins.

Small G-protein GEF/GAP and ELISA Kits

In vitro kits for measuring modulation of GTPase activity and protein levels.

Small G-proteins

High-purity, biologically active Ras superfamily proteins—wild type & mutant—ideal for reliable in vitro assays.

Modulator Proteins

High-purity, biologically active GTPase modulators, such as SOS1, are ideal for in vitro assays.

Small G-protein Antibodies

Rac1 & Cdc42 mAbs – each Lot QC'd for trusted results.

Small G-protein Buffers

Ready-to-use buffers and reagents designed to streamline and support your small GTPase research workflows.

Featured products

Feedback from the bench

In biology, we need consistency and reproducibility in our assays and experiments. Whenever I see a product from Cytoskeleton, in my brain it's already fixed — okay, good, I know I will get the consistency I need.”
Satya Malasala, PhD

Satya Malasala, PhD

Postdoctoral Scholar

University of South Carolina

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Tel: 303-322-2254

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