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Custom assay development

Drive your research forward with Cytoskeleton’s custom assay development services. With over 30 years of expertise in cytoskeletal biology, signal transduction, and protein biochemistry, we have what it takes to deliver reliable assays that accelerate your discovery, target validation, and lead optimization efforts.

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Expert assay development services

From novel cancer targets to microtubule dynamics, Cyto’s assay development services are designed to meet the rigorous demands of protein-centric research.

Whether you need a bridge solution while building in-house capabilities or a specialized partner to develop assays outside your core expertise, we’re ready to help you achieve your project goals.

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Why choose us?

Cytoskeleton partners closely with your team to deliver custom assays, leveraging deep expertise in cytoskeletal biology and protein biochemistry. Our high-quality data supports key project decisions, while our focus on collaboration and reliability keeps leading pharma and biotech companies returning year after year.

Proven expertise

  • For 30+ years, a trusted name in protein biochemistry
  • Broad portfolio of validated custom biochemical assays
  • Proven track record supporting drug discovery pipelines
  • Rapid formulation of lyophilized reagents optimized for HTS use

Reliable, robust results

  • Low variability (CV <6%) ensures highly reproducible data
  • Rigorous, multi-parameter, QC protocol
  • Detailed documentation

Collaborative approach

  • Dedicated, PhD-level, assay development specialists
  • Proactive, responsive technical support
  • Expert scientific collaboration tailored to project needs
  • Weekly meetings with assay developer lead and project manager

Fast, reliable delivery

  • Rapid custom assay development, often with 6–8 week turnarounds
  • Efficient project management
  • Reliable, timely data to support critical research decisions
  • >97% client satisfaction, >80% returning customers

Assay development in action

K-Ras inhibitor profiling

A Fortune 500 biopharmaceutical company needed a fast, sensitive immunoassay to characterize K-Ras inhibitors.

Our team developed a customized K-Ras G-LISA assay optimized for cell lysate inputs. We delivered lyophilized reagents, complete protocols, and an easy-to-interpret assay. Our custom G-LISA assay became a reliable decision-making tool during hit-to-lead evaluation and was used to profile compounds in their search for novel anti-cancer drug development candidates.

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Targeting mitotic kinesins

A biotech company sought comprehensive tools to characterize inhibitors targeting a mitotic kinesin linked to cancer progression. Our custom services team collaborated closely with the client to deliver a complete solution, including functional protein production, custom assay development, and compound screening.

This integrated solution allowed rapid identification and validation of hits, streamlined lead refinement, and delivered reproducible, high-quality data. As a result, the client gained a robust platform to accelerate inhibitor optimization and advance their cancer therapeutics pipeline.

Download case study

Our clients

We proudly support leading research teams across pharma, biotech, and academia. Our assay development services have helped advance discovery and preclinical programs in oncology, neuroscience, cardiology, and beyond.

  • Merck & Co., Inc.
  • Astra-Zeneca plc
  • Eli Lilly & Co.
  • GlaxoSmithKline plc
  • Amgen, Inc.
  • Genentech, Inc.
  • Abbott Laboratories
  • Johnson & Johnson
  • Pfizer, Inc.
  • Bristol-Myers Squibb

Ready to start your custom assay development project?

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