Live Cell Imaging Reagents
Dyes/Substrates

Bioimaging substrates & reactive dyes

At Cyto, we are proud to offer an extensive selection of high-performance Spirochrome™ dyes and substrates, designed to elevate your cell biology and biochemical research.

  • SNAP-tag® reagents – SiR and SPY-derivatized benzylguanine (BG) substrates offer superior SNAP reagents for live cell imaging of your SNAP-tag® fusion protein of interest (POI).
  • Halo-tag® reagents – SiR and SPY-derivatized chloroalkane (CA) substrates offer superior HALO reagents for live cell imaging of your HALO-Tag® fusion protein of interest (POI).
  • RNA markers - SPYRHO 555 provides fast-binding kinetics, photostable fluorescence for advanced live cell RNA imaging.
  • Reactive dyes for protein labeling and click chemistry – The Spirochrome line of reactive dyes include amine (NHS ester), thiol (maleimide), and carboxylic acid labels for proteins and biomolecules, plus clickable azide, alkyne, and tetrazine reagents for versatile bioconjugation and click chemistry.

SNAP-tag® is a registered trademark of New England Biolabs, Inc.

HaloTag® is a registered trademark of Promega

At Cyto, we are proud to offer an extensive selection of high-performance Spirochrome™ dyes and substrates, designed to elevate your cell biology and biochemical research.

  • SNAP-tag® reagents – SiR and SPY-derivatized benzylguanine (BG) substrates offer superior SNAP reagents for live cell imaging of your SNAP-tag® fusion protein of interest (POI).
  • Halo-tag® reagents – SiR and SPY-derivatized chloroalkane (CA) substrates offer superior HALO reagents for live cell imaging of your HALO-Tag® fusion protein of interest (POI).
  • RNA markers - SPYRHO 555 provides fast-binding kinetics, photostable fluorescence for advanced live cell RNA imaging.
  • Reactive dyes for protein labeling and click chemistry – The Spirochrome line of reactive dyes include amine (NHS ester), thiol (maleimide), and carboxylic acid labels for proteins and biomolecules, plus clickable azide, alkyne, and tetrazine reagents for versatile bioconjugation and click chemistry.

SNAP-tag® is a registered trademark of New England Biolabs, Inc.

HaloTag® is a registered trademark of Promega

Cytoskeleton, Inc
Contact UsMy Account

Tel: 303-322-2254

  • Blogs
  • FAQ's
  • Datasheets and MSDS
  • Protocols
  • Learning Documents
  • Videos
  • About Us
  • Careers
  • Distributors
  • All Services
  • Compound Screening
  • Protein Purification
  • Assay Development
  • Post-Translational Modification (PTM) Tools
  • Motor Protein Products
  • Live Cell Imaging Reagents
  • Actin Products
  • ECM Proteins
  • Small G-protein Products
  • Tubulin & FtsZ Products
  • General Protein Tools
Linkedin

© 2026 Cytoskeleton, Inc All Rights Reserved.

Privacy Policy

TEL: 303-322-2254

Log in to your Account
Cytoskeleton, IncCytoskeleton, Inc
Your quote is empty.
My Cart
( Items)
  • Cytoskeleton, Inc
  • Products
    • Featured New Product
    • Small G-protein Products
      • Small G-protein Activators & Inhibitors
      • Small G-protein Activation Assays
      • Small GTPase Affinity Beads
      • Small G-protein GEF/GAP and ELISA Kits
      • Small G-proteins
      • Modulator Proteins
      • Small G-protein Antibodies
      • Small G-protein Buffers
    • Post-Translational Modification (PTM) Products
      • Ubiquitination Tools
      • Acetyl-Lysine Tools
      • SUMOylation Tools
      • Phosphotyrosine Tools
      • Actin Oxidation Tools
      • Antibodies: PTMtrue™
      • Cell Lysis Tools
    • Tubulin & FtsZ Products
      • Tubulin Kits
      • Microtubules & Tubulin Proteins
      • Fluorescent and Labeled Tubulins
      • Microtubule-Associated Proteins (MAPs)
      • Live Cell Tubulin Reagents
      • Tubulin Antibodies
      • FtsZ Proteins
      • Tubulin Drugs and Buffers
    • Actin Products
      • Acti-stain™ Fluorescent Phalloidins
      • Actin Assays & Kits
      • Actin Proteins
      • Fluorescent and Labeled Actin
      • Actin Binding Proteins
      • Live Cell Actin Reagents
      • Actin Oxidation Tools
      • Actin Antibodies
      • Actin Drugs & Buffers
    • Live Cell Imaging Reagents
      • Live Cell Actin Reagents
      • Live Cell Tubulin Reagents
      • Small G-protein Activators & Inhibitors
      • Nuclear DNA Probes
      • Live Cell Membrane Probes
        • Plasma Membrane Probes
        • Membrane Tension Probes
        • Membrane Polarity Probes
      • Live Cell Mitochondrial Reagents
      • ECM Proteins
        • Fluorescent Fibronectin
        • Fluorescent Laminin
      • Live Cell Lipid Droplets
      • Other Organelles
      • Dyes/Substrates
    • ECM Proteins
      • Fluorescent Fibronectin
      • Fluorescent Laminin
    • Motor Protein Products
      • Motor Kits and Assays
      • Kinesin Proteins
      • Myosin Proteins
      • Dynein Proteins
      • Motor Protein Drugs & Buffers
    • General Protein Tools
      • Protein Quantitation
      • Cell Lysis Tools
      • ATPase & GTPase Assays
      • Other Protein Tools
    • GO-Blot V2 - Fully Automated And Programmable Western Blot Processor
  • Custom Services
    • All Services
    • Compound Screening
      • Tubulin Polymerization Assay Services
      • Kinesin ATPase Screening Services
      • Myosin ATPase Screening Services
      • GTP Exchange Factor (GEF) Assay Services
      • GTPase Activating Protein (GAP) Assay Services
      • FtsZ GTPase and Polymerization Assay Services
      • GTPase Activation Screening Services
    • Protein Purification
    • Assay Development
  • Resources
    • Resource Hub
      • Blogs
      • Videos
      • Protocols
      • Learning Documents
        • Ebook
    • FAQs
    • Datasheets and MSDS
  • About Us
    • About Us
    • Careers
    • Distributors
  • Contact Us
Your cart is empty.