• Perform live cell RNA imaging

SPYRHO 555 is a spirocyclic rhodamine probe designed for aptamer-based super-resolution microscopy.

Key features

• Ab: 562 nm, Em: 581 nm – yellow/orange
• High affinity & fast on/off kinetics
• Works for live or fixed cells
• Cell permeable
• Fluorogenic character: enhanced fluorescence when bound to aptamer
• Compatible with super-resolution microscopy (STED & SMLM)

The biological activity of CY-SC018 is assessed by the ability of the probe to efficiently stain RhoBAST RNA in live cell culture.