Spirochrome: SiR700 Probes

The SiR700 series of probes is based on the far-red silicon rhodamine (SiR) fluorophore analogue SiR700. These live-cell imaging probes developed by Spirochrome are cell-permeable compounds which stain microtubules (SiR700-Tubulin), F-actin (SiR700-Actin), Lysosomes (SiR700-Lysosome) and chromosomal DNA (SiR700-DNA) in living cells similarly to the original SiR probes.  In combination with standard SiR-probes, SiR700-actin allows dual colour imaging experiments in live cells.