Lipibright™ Fluorogeneic Lipid Droplet Probes

Cytoskeleton is proud to announce 3 new bright fluorogenic probes to visualize lipid droplets. LipiBright™ live cell probes fluoresce 300 to 1000 times brighter in an oily/lipid environment compared to aqueous solutions and effectively label lipid droplets1.  

Advantages:

  1. LipiBright probes are photostable and possess narrow absorption and emission bands, a distinct advantage over the traditional Nile Red probe; thus, multicolor imaging is possible.
  2. These probes exhibit ideal characteristics for microscopy and have been validated with multiple techniques including epifluorescent (widefield), confocal, and two photon.

LipiBright™ 530 SMCy3.5: Fluorogenic Lipid Droplet Probe (MG11)

LipiBright™ 650 SMCy5.5: Fluorogenic Lipid Droplet Probe (MG12  

LipiBright™ 700 SMCy7.0: Fluorogenic Lipid Droplet Probe (MG13)  

Figure. Swiss3T3 cell monolayer labeled with LipiBright™ SMCy3.5. Widefield fluorescent imaging of live Swiss3T3 labeled with LipiBright™ SMCy3.5 (Pink), a live cell actin cytoskeleton stain (Green, SPY650), and a live cell DNA probe (Blue, SPY505-DNA).

Figure.Swiss3T3 cell monolayer labeled with LipiBright™ SMCy3.5. Widefield fluorescent imaging of live Swiss3T3 labeled with LipiBright™ SMCy3.5 (Pink), a live cell actin cytoskeleton stain (Green, SiR-Actin), and a live cell DNA probe (Blue, SPY505-DNA).