• Label proteins containing unnatural amino acids (UAAs) through click chemistry
• Visualize targeted proteins with site specific, super-resolution microscopy

SiR-tetrazine is a clickable derivative of SiR dye. CY-SC008 rapidly reacts with dienophiles such as trans-cyclooctene (TCO) or bicyclononyne (BCN) derivatives that are commonly used in the design of UAAs.

Key features

Ab: 652 nm, Em: 674 nm – far-red spectrum

• Emission in far-red minimizes phototoxicity and sample autofluorescence
• High specificity and speed of reaction with UAAs
• Live cell compatible, cell permeable
• High extinction coefficient
• Fluorogenic character
• High photostability
• Compatible with widefield, confocal, STED and SIM microscopy