• Fluorogenic far-red stain for microtubules in live cells and tissues
• Supports multicolor imaging

SiR700-tubulin is based on the silicon rhodamine (SiR) fluorophore analogue SiR700 and the microtubule-binding drug Docetaxel. SiR700-tubulin allows the labelling of microtubules in live cells with high specificity and low background.

Key features

• Ab: 689 nm, Em: 716 nm – far-red spectrum
• Emission in far-red minimizes phototoxicity and sample autofluorescence
• Cell permeable
• Non-toxic
• Fluorogenic character: enhanced fluorescence when bound to microtubules
• Compatible with super-resolution microscopy (STED & SIM)

The biological activity of CY-SC014 is assessed by the ability of the probe to efficiently label microtubules in live cell culture. After a wash step, cell staining is visible for several hours. SiR700-tubulin is not recommended for fixed cells.