KIF4 (chromokinesin) is a kinesin motor protein involved in chromosome condensation, spindle formation, and cytokinesis during cell division. It plays a crucial role in intracellular transport and proper segregation of genetic material, making it essential for maintaining genomic stability.
The wild-type human motor domain of KIF4 is produced in a bacterial expression system.
Protein purity is assessed by scanning densitometry of Coomassie Blue-stained protein on a4-20% polyacrylamide gel. Purity is determined to be >50% pure.
Biological activity of KIF10 is measured using a microtubule-activated ATPase assay. Under the conditions stated (see datasheet) KIF20A exhibits a microtubule-stimulated ATPase activity with a Vmax of ≥ 300 nmol of ATP produced per minute per mg of KIF4.
Cat. #CR01
