New Signal-Seeker™: PTM detection kits, antibodies, and reagents

Simplicity

Comprehensive kit minimizes optimization time, while maximizing PTM detection

Quality

Unparalleled sensitivity and precision to confidently identify low abundance PTMs

Integration

Study multiple PTMs using the same system

Browse through the products, resources, and background options below to see how Signal-Seeker™ kits and reagents can enhance your protein modification detection research.

Cytoskeleton's products have been cited hundreds of times over the past 29 years. Example citations for the BK161 Ubiquitination Detection kit, BK161, is shown, but more citations are available on individual product pages. Please use the "Citations" tab on each individual product page.


AuthorTitleJournalYearArticle Link
Afrin, Sadia et al.Simvastatin modulates estrogen signaling in uterine leiomyoma via regulating receptor palmitoylation, trafficking and degradationPharmacological Research2021ISSN 1096-1186
Tumova, Lucie et al.The ubiquitin-proteasome system does not regulate the degradation of porcine β-microseminoprotein during sperm capacitationInternational Journal of Molecular Sciences2020ISSN 1422-0067
Gu, Chunming et al.Identification of berberine as a novel drug for the treatment of multiple myeloma via targeting UHRF1BMC Biology2020ISSN 1741-7007
Chu, Yi et al.O-GlcNAcylation of SIX1 enhances its stability and promotes hepatocellular carcinoma proliferationTheranostics2020ISSN 1838-7640
Uchiyama, Makoto et al.O2-Dependent Protein Internalization Underlies Astrocytic Sensing of Acute Hypoxia by Restricting Multimodal TRPA1 Channel ResponsesCurrent Biology2020ISSN 1879-0445
Sen, Arpita et al.The Na+ pump Ena1 is a yeast epsin-specific cargo requiring its ubiquitylation and phosphorylation sites for internalizationJournal of Cell Science2020ISSN 1477-9137
Park, Jin Suk et al.Mechanical regulation of glycolysis via cytoskeleton architectureNature2020ISSN 1476-4687

Signal-Seeker PTM Detection Kits

  1. Signal-Seeker™ Ubiquitination Detection Kit (30 assay) BK161
    Signal-Seeker Ubquitination Detection Kit (30 assays, immunoprecipitation format) Learn More
  1. Signal-Seeker™ Acetyl-Lysine Detection Kit (30 assay) BK163
    Signal Seeker Acetylation Detection Kit (30 assays, immunoprecipitation format) Learn More
  1. Signal-Seeker™ SUMOylation 2/3 Detection Kit (30 assay) BK162
    Signal Seeker SUMOylation 2/3 Detection Kit (30 assays, immunoprecipitation format) Learn More
  1. NEW Signal-Seeker™ SUMOylation 1 Detection Kit (30 assay) BK165
    Signal Seeker SUMOylation 1 Detection Kit (30 assays, immunoprecipitation format) Learn More
  1. Signal-Seeker™ Phosphotyrosine Detection Kit (30 assay) BK160
    Signal Seeker Phosphotyrosine Detection Kit (30 assays, immunoprecipitation format)
    Learn More
  1. Signal-Seeker™ Ubiquitination Detection Kit (10 assay) BK161-S
    Signal-Seeker Ubquitination Detection Kit (10 assays, immunoprecipitation format) Learn More
  1. Signal-Seeker™ Acetyl-Lysine Detection Kit (10 assay) BK163-S
    Signal Seeker Acetylation Detection Kit (10 assays, immunoprecipitation format) Learn More
  1. Signal-Seeker™ SUMOylation 2/3 Detection Kit (10 assay) BK162-S
    Signal Seeker SUMOylation 2/3 Detection Kit (10 assays, immunoprecipitation format) Learn More
  1. NEW Signal-Seeker™ SUMOylation 1 Detection Kit (10 assay) BK165-S
    Signal Seeker SUMOylation 1 Detection Kit (10 assays, immunoprecipitation format) Learn More
  1. Signal-Seeker™ Phosphotyrosine Detection Kit (10 assay) BK160-S
    Signal Seeker Phosphotyrosine Detection Kit (10 assays, immunoprecipitation format) Learn More

Signal-Seeker PTM Affinity Beads

  1. Ubiquitination Affinity Beads UBA01-beads
    Ubiquitination Affinity Beads (40 assays) Learn More
  1. Acetyl-Lysine Affinity Beads AAC04-Beads
    Acetyl-lysine Affinity Beads (40 Assays) Learn More
  1. SUMOylation 2/3 Affinity Beads ASM24-Beads
    SUMO-2/3 Antibody Mouse Monoclonal (20 assays) (Agarose bead conjugate) Learn More
  1. NEW SUMOylation 1 Affinity Beads ASM11-beads
    SUMO1 Antibody Mouse Monoclonal (30 assays) (Agarose bead conjugate) Learn More
  1. Phosphotyrosine Affinity Beads APY03-Beads
    Phosphotyrosine AffinityBeads (40 Assays) Learn More
  1. Ubiquitination Control Beads CUB02-beads
    Ubiquitination Control Beads (10 assays) Learn More
  1. IgG Control Beads CIG01-beads
    IgG Control Beads (10 assays) Learn More
  1. Acetyl-Lysine Control Beads CIG02-beads
    Acetyl Lysine Control Beads (10 assays) Learn More
  1. SUMO1 IP Control Beads CIG03-beads
    SUMO1 IP Control Beads (12 assays) Learn More

Signal-Seeker PTM True Antibodies

  1. Ubiquitin-HRP Antibody Mouse Monoclonal AUB01-HRP
    Ubiquitin-HRP Mouse Monoclonal Antibody Learn More
  1. Acetyl Lysine Antibody Mouse Monoclonal AAC01
    Acetyl Lysine Mouse Monoclonal Antibody
    Learn More
  1. SUMO-2/3 Antibody Mouse Monoclonal (Clone 12F3) ASM23
    SUMO-2/3 Antibody Mouse Monoclonal (Clone 12F3) Learn More
  1. SUMO-2/3-HRP Antibody Mouse Monoclonal (Clone 12F3) ASM23-HRP
    SUMO-2/3-HRP Antibody Mouse Monoclonal (Clone 12F3) Learn More
  1. NEW SUMO1 Antibody Mouse Monoclonal (Clone 5D8B16) ASM01
    SUMO1 Antibody Mouse Monoclonal (Clone 5D8B16) Learn More
  1. Phosphotyrosine Antibody Mouse Monoclonal 27B10 APY03
    Phosphotyrosine Mouse Monoclonal Antibody 27B10
    Learn More
  1. Phosphotyrosine-HRP Mouse Monoclonal Antibody 27B10 APY03-HRP
    Phosphotyrosine-HRP Mouse Monoclonal Antibody 27B10 Learn More

Signal-Seeker Actin Oxidation Tools

  1. MICAL-Oxidized Actin Protein (>95% pure): Rabbit Skeletal Muscle MXA95
    MICAL-Oxidized Actin Protein (>95% pure): Rabbit Skeletal Muscle (250 micrograms) Learn More
  1. MICAL-Oxidized (Pyrene labeled) Actin Protein (>95% pure): Rabbit Skeletal Muscle MPAX1
    MICAL-Oxidized Pyrene Actin Protein (>95% pure): Rabbit Skeletal Muscle (250 micrograms) Learn More
  1. MICAL-1 Protein 6xHis MIC01
    6xHis MICAL-1 Protein Redox-CH domains (2 x 50 micrograms) Learn More
  1. MsrB2 Protein 6xHis MB201
    6xHis MsrB2 Protein aa: 42-182 (2 x 50 micrograms) Learn More

Signal-Seeker BlastR Lysis System

  1. BlastR Rapid Lysate Prep Kit BLR01
    BlastR Rapid Lysate Prep Kit (50 filters) Learn More
  1. BlastR Rapid Filtration Kit BLR02
    BlastR Rapid Filtration Kit (50 filters) Learn More