• Fluorogenic, far-red stain for DNA in live cells and tissues
• Fluorogenic, far-red stain for DNA in fixed cells
• Fluorogenic, far-red stain for nuclear staining in fixed and live cells
• Compatible with multicolor imaging

SPY700-DNA probe comprises SPY™ dye conjugated the DNA minor groove binder bisbenzimide (Hoechst). SPY700-DNA allows the labelling of DNA/nucleus in live cells with high specificity and low background.

Key features

• Ab: 696 nm, Em: 718 nm- far-red spectrum
• Emission in far-red minimizes phototoxicity and sample autofluorescence
• Cell permeable
• Bright
• Works on live or fixed cells
• Fluorogenic character: enhanced fluorescence when bound to DNA
• Compatible with widefield, confocal, STED & SIM imaging

The biological activity of CY-SC601 is assessed by the ability of the probe to efficiently label DNA (nucleus) in live cell HeLa culture. After an optional wash step, cell staining is visible for several hours. If performing time lapse it is recommended to omit the wash step.