• Fluorogenic far-red stain for microtubules in live cells and tissues
• Supports multicolor imaging

SPY™650-tubulin probe comprises SPY™ dye conjugated to the microtubule-binding drug docetaxel. Its fluorogenic nature allows the labelling of microtubules in live cells with high specificity and low background.

Key features

• Ab: 652 nm, Em: 674 nm – far-red spectrum
• Cell-permeable
• Works on live cells and tissues
• Fluorogenic character: enhanced fluorescence when bound to microtubules
• Compatible with widefield, confocal, SIM, and STED imaging

The biological activity of CY-SC503 is assessed by the ability of the probe to efficiently label microtubules in live HeLa cell culture. After a wash step, cell staining is visible for several hours. If performing longer term time-laps readings it is recommended to keep the probe in the image media with no wash step.