ECM Resource Directory

Formation of the extracellular matrix (ECM) requires cells to secrete ECM proteins. Assembly is achieved by following a strict hierarchical assembly pattern which begins with the deposition of fibronectin filaments on the cell surface, a process known as fibrillogenesis (1).  Cells continue to remodel the ECM by degradation and reassembly mechanisms, the dynamic nature of the ECM being... (Read more about ECM here).