Small GTPase affinity beads
Isolate active, GTP-bound forms of small G-proteins—such as Rac1, RhoA, Cdc42, RalA, Arf1 & Arf6—using agarose affinity beads conjugated to specific effector domains. These affinity beads selectively bind GTPases in their active conformation directly from cell lysates. Following affinity enrichment, proteins are analyzed by SDS-PAGE and western blot using GTPase-specific antibodies.
This tool is ideal for investigating signaling pathways, cytoskeletal dynamics, and disease-related processes such as cancer progression, metastasis, and immune cell activation.
Isolate active, GTP-bound forms of small G-proteins—such as Rac1, RhoA, Cdc42, RalA, Arf1 & Arf6—using agarose affinity beads conjugated to specific effector domains. These affinity beads selectively bind GTPases in their active conformation directly from cell lysates. Following affinity enrichment, proteins are analyzed by SDS-PAGE and western blot using GTPase-specific antibodies.
This tool is ideal for investigating signaling pathways, cytoskeletal dynamics, and disease-related processes such as cancer progression, metastasis, and immune cell activation.
