Spirochrome: PKmito™ Probes
We are proud to announce that the PKmito™ probes for gentle imaging of mitochondria in live cells have been developed and published by the lab of Zhixing Chen from Peking University1,2). They were carefully designed to reduce the generation of reactive oxygen species during imaging and allow long-term imaging or timelapse STED imaging in live cells.
Advantages:
- PKmito™ probes are ideal for gentle mitochondria imaging
- due to the low phototoxicity, long term live cell imaging with confocal or widefield is allowed
- PKmito ORANGE is the ideal STED probe for mitochondria, staining the inner membrane and therefore revealing mitochondrial cristae
Click Here to See These Probes in Action
1. Liu Tianyan et al. “Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain” PNAS (2022):119 (52).
2. Yang, Zhongtian, et al. “Cyclooctatetraene-conjugated cyanine mitochondrial probes minimize phototoxicity in fluorescence and nanoscopic imaging.” Chemical science 11.32 (2020): 8506-8516.
Cytoskeleton, Inc. is the exclusive provider of Spirochrome, Ltd. products in North America.
Click Here to see videos of this probe in action