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MICAL-Oxidized Actin Tools: Discover the Next Level of Actin Regulation

Physiologic and reversible methionine oxidation of actin at Met44 and Met47 by the redox protein Mical and the reductase MsrB has been shown to drastically affect actin depolymerization as well as actin dependent cellular and physiological processes.

Actin Met 44 and Met 47 physiological redox system

Figure legend: A schematic diagram of the enzymes that control the physiological and reversible oxidation and reduction of methionines 44 and 47 of actin.

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Cytoskeleton provides many kits for basic research including kits to study cofilin, vinculin, actin binding proteins, cortactin, dynein, kinesin, cell migration, cell division, mitosis, meiosis, cytokinesis, plasma-membrane, fluorescence, actin, tubulin, phagocytosis, we also supply SiR-actin, Flipper-TR, GEFs such as SOS1, Tiam, Vav1 and Vav2 and small g-proteins such as Ras, K-Ras, Rho, Rac1 and Cdc42, in elisa and glisa formats..

Select from the categories below:

  1. Flipper-TR Kit for fluorescence cell membrane microscopy CY-SC020
    Flipper-TR Kit, a probe for measuring plasma-membrane tension.
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