Introducing the new SPY Probes
In 2015, Cytoskeleton introduced multiple live cell imaging probes from Spirochrome company. These revolutionary probes simplified and stream-lined live cell imaging. Now in 2019, Cytoskeleton is excited to introduce the next generation of Spirochrome's live cell imaging probes - the SPY probes. SPY probes improve upon the SiR and SiR700 live cell imaging probes in the far-red channels while also expanding the fluorophore labeling options for the study of F-actin, microtubules, and DNA in living cells. Here is the new list of probes:
SPY probes capitalize on all of the benefits and advantages of SiR probes, while also offering substantial improvements including:
Fluorogenic - background is even less than that of SiR and SIR700 probes
Multiple Fluorophore Options (e.g., far-red, orange, red, and green)
Sensitive and Selective
Improved Cell Permeability (i.e. no longer need verapamil)
Follows the same protocols as for SiR with shorter incubation times and lower concentrations
Increased intracellular stability i.e. probes last longer
HeLa cell in mitosis using Spirochrome probes.
Cytoskeleton provides many kits for basic research including kits to study cofilin, vinculin, actin binding proteins, cortactin, dynein, kinesin, cell migration, cell division, mitosis, meiosis, cytokinesis, plasma-membrane, fluorescence, actin, tubulin, phagocytosis, we also supply SiR-actin, SiR-DNA, SiR-Tubulin, SiR-Lysosome, SPY-actin, SPY-DNA, SPY-Tubulin, Flipper-TR, GEFs such as SOS1, Tiam, Vav1 and Vav2 and small g-proteins such as Ras, K-Ras, Rho, Rac1 and Cdc42, in elisa and glisa formats.