New bright fluorogenic MemGlow™ probes* for cell membranes now available!
Cytoskeleton is proud to announce 3 new bright fluorogenic probes to visualize the cellular plasma membrane. Originally developed as the MemBright™ probes, MemGlow™ probes provide high photostability, exhibit excellent fluorescent quantum yields, and some of them are super-resolution compatible.
MemGlow™ probes are chemically composed of cyanine or BODIPY dyes bearing zwitterionic amphiphilic anchors for enhanced retention in the plasma membrane.
The fluorogenic nature of MemGlow™ probes translates to minimal fluorescent emission until their contact with the plasma membrane elicits integration into the lipid bilayer. This characteristic creates minimal background, bright plasma membrane localization, and a no-wash-required application.
MemGlow™ probes are highly efficient and allow scientists to visualize cellular nanostructures with nanomolar probe concentrations.
Features and advantages of MemGlow™ probes:
For an in-depth look at MemGlow™ probes (part of the MemBright™ family) view their groundbreaking publication by clicking this link.
Turn-on mechanism of MemGlow™ probes. MemGlow™ probes are self-quenched nanoparticles until integration with the plasma membrane enables their excitation.