April Newsletter: Rac1 in Diabetes: The Good and Bad

Elevations in blood glucose levels are sensed in pancreatic b-cells, which respond through a complex signaling pathway involving mitochondrial-dependent glucose metabolism1. The culmination of this pathway is the mobilization of intracellular insulin-loaded vesicles that fuse with the cell membrane releasing their contents into the...

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Also included in this newsletter:

• Rac1 Activation Assays, Antibodies, Custom GEF Screenings and New Signal Seeker Kits
• Related Publications