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The Ras GTPase superfamily, which includes Ras, Rho, Rab, Arf, and Ran subfamilies (among others), has been shown to regulate a wide spectrum of cellular functions. GTPases function as molecular switches, cycling between an inactive GDP-bound form and an active GTP-bound form. The Rho GTPase subfamily includes Rho, Rac, and CDC42, and is believed to be involved primarily in the regulation of cytoskeletal organization in response to extracellular growth factors...

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Also included in this newsletter:

 

  • Antibodies, G-Switch Activators and Inhibitors, Activation Assays, G-protein Effector Proteins and Kits, NEW Signal Seeker Kits

 

  • Related Publications

 

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alex castellanos