A20 ubiquitin binding, not its catalytic activity, is important in Rheumatoid Arthritis (RA)
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- Oct 5, 2023
Leveraging SUMOylation To Regulate Immune Response
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- Aug 8, 2023
MTSS1 Curtails Lung Adenocarcinoma Immune Evasion by Promoting AIP4-Mediated PD-L1 Monoubiquitination and Lysosomal Degradation
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- Jun 20, 2023
Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation
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- Feb 14, 2023
Regulation of Chromatin Accessibility in Cellular Reprogramming: Pioneer Transcription Factors, Epigenetics and Nuclear Actin
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- Jul 6, 2022
Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
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- Jun 23, 2022
Controlling Ubiquitination is Key in the War with Bacteria
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- May 4, 2022
SARS-CoV-2 Evades Innate Immunity: Focusing on Ubiquitination
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- Dec 2, 2021
Therapeutic targeting of the Ubiquitin Pathway
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- Jul 22, 2021
O2-Dependent Protein Internalization Underlies Astrocytic Sensing of Acute Hypoxia by Restricting Multimodal TRPA1 Channel Responses
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- Jul 8, 2021
Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy
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- Oct 22, 2020
Citation Spotlight: Mechanical Regulation of Glycolysis via Cytoskeleton Architecture
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- Jul 28, 2020
Citation Spotlight: Ubiquitination of renal ENaC subunits in vivo
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- Apr 15, 2020
Citation Spotlight: Stability of HTLV-2 antisense protein is controlled by PML nuclear bodies in a SUMO-dependent manner
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- Aug 19, 2019
June Newsletter: Actin Methionine Oxidation: The Next Level of Dynamic Regulation
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- Jul 15, 2019
Citation Spotlight: Myeloid-Specific Deletion of Epsins 1 and 2 Reduces Atherosclerosis by Preventing LRP-1 Downregulation
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- May 23, 2019
July Newsletter: SUMO Wrestling: All About Balance
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- Jul 10, 2018
Citation Spotlight: Identifying Potential PTM Crosstalk of Acetylated Mitochondrial Proteins
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- Jun 18, 2018
May Newsletter: Ubiquitin-Proteasome System as a Therapeutic Target: Does Tubulin Care?
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- Apr 30, 2018
March Newsletter: Post-translational Modifications of β-catenin and TCF/LEF-1 Regulate Canonical Wnt Signaling
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- Mar 13, 2018
February Newsletter: Post-translational Modifications Modulate p53 Tumor Suppressor Functions
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- Feb 20, 2018
Citation Spotlight: Tools and Protocols for Successful PTM Investigation for Target Proteins
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- Feb 8, 2018
Citation Spotlight: Acetylated Microtubule Bundling, MAP Binding, and Functional Regulation of Kinesin-1
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- Jan 3, 2018
November Newsletter: Mitochondrial Acetylation: Emerging Concepts and Therapeutic Potential
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- Dec 11, 2017
September Newsletter: Microtubule Stabilization by the Post-translational Modification of Acetylation
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- Sep 11, 2017
Citation Spotlight: Toolsets to Define PTMs for Any Target Protein
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- Aug 8, 2017
July Newsletter: Post-translational Regulation of Mdm2, an E3 Ubiquitin Ligase for Tumor Suppressor p53
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- Jul 26, 2017
June Newsletter: Posttranslational Regulation of Key Transcription Factors in Pluripotent Stem Cells
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- Jun 13, 2017
April Newsletter: Post-translational Regulation of Phosphatase and Tensin Homolog (PTEN)
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- Apr 18, 2017
Citation Spotlight: PD-L1: Regulation by the Post-Translational Modification of Monoubiquitination
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- Mar 29, 2017
August Newsletter: Tyrosine phosphorylation regulates Rho family GTPase activity
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- Aug 3, 2016
July Newsletter: PTMs Regulate Cytoskeletal Proteins in Heart Disease
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- Jul 12, 2016
Lysine Acetyltransferase p300 and Its Role in Skeletal Muscle Biology
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- Mar 24, 2016
SUMOylation: Functional Regulator of Cytoskeletal Proteins
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- Mar 9, 2016
Vimentin Intermediate Filaments: Regulation by Phosphorylation
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- Jan 21, 2016
Post-translational Modifications - Essential for Protein Regulation
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- Aug 3, 2015
SUMOylation of Mitotic Proteins: Localization and Function
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- Jun 2, 2015
Citrullination: Taking the Charge out of Arg
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- Oct 23, 2014
SUMOylation: A Post-translational Modification Targeting Cytoskeletal Proteins
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- Aug 4, 2014
Lysine Acetylation - Regulator of Diverse Cellular Processes
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- Apr 3, 2014
Neurodegeneration: Rhes, SUMOylation, and Huntington's Disease
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- Sep 27, 2013
Monoubiquitination and Protein Regulation
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- Sep 10, 2013
Tau PTMs as Therapeutic Targets
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- Mar 31, 2013
Ubiquitination and the Regulation of Rho Family Pathways
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- Oct 1, 2012