This newsletter describes the pros and cons of commonly used fluorescent membrane probes and provides an overview of the latest probe breakthroughs. Luminescent membrane probes delineate the periphery of a cell by binding close to or within the plasma membrane. There are, broadly speaking, five classes of membrane probes, which are; wheat germ agglutinin (WGA) conjugates, lipid conjugates, lipophilic dyes, covalent binding probes, and biophysical reporter probes. Recently, new fluorogenic probes have been developed including MemGlow™ (MemBright™ family), Flipper-TR5a and Nile Red-based probes, which bestow researchers unprecedented resolution of membrane structure and function, and with the latter two acting as biophysical sensors.
Also included in this newsletter:
- Tubulin and Actin Live Cell Reagents, G-LISA Activation Assay Kits, Tubulin Kits, Actin Biochem Kits
- Related Publications