Microtubules and Motor-Driven Cargo Delivery

Microtubules, composed of alpha- and beta-tubulin heterodimers, are one of the most recognizable filamentous structural proteins in the dynamic cytoskeleton network.  Its function in mitosis and cell division is integral to growth and viability, but its essential role in intracellular organization during interphase is just as important.  One core function is its role in cargo transport where microtubule networks have been compared to highways and byways utilized by motor proteins to transport cargo such as vesicles, organelles, protein complexes and many other cell components (1).  So what’s new in the world of microtube/motor-driven cargo transport and what’s regulating it?  Exciting new research is adding to our understanding of the dynamic microtubule/motor cargo system and its effect on disease.

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Also included in this newsletter:

• PTM Detection, Tubulin Live Cell Imaging, Tubulin and Motor Proteins
• Related Publications